For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
LCQTCRVGKRRDAREQIEAKIVELGRRQLLDHGAAGLSLRAIARNLGMVSSAVYRYVSSRDELLTLLLVD AYSDLADTVDRARDDTVADSWSDDVIAIARAVRGWAVTNPARWALLYGSPVPGYHAPPDRTAGVATRVVG AFFDAIAAGIATGDIRLTDDVAPQPMSSDFEKIRQEFGFPGDDRVVTKCFLLWAGVVGAISLEVFGQYGA DMLTDPGVVFDAQTRLLVAVLAEH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1846 | - | - | 100% (234) | transcriptional regulatory protein |
| M. bovis AF2122 / 97 | Mb0672c | - | 9e-06 | 22.81% (228) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3414 | - | 5e-78 | 61.23% (227) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1816 | - | 1e-132 | 100.00% (234) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4787c | - | 5e-26 | 33.18% (214) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4115 | - | 8e-06 | 30.49% (82) | putative regulatory protein |
| M. avium 104 | MAV_2899 | - | 1e-102 | 80.26% (228) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3659 | - | 6e-75 | 61.23% (227) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_4347 | - | 2e-07 | 25.96% (208) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_0743 | - | 2e-06 | 26.58% (222) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_3167 | - | 2e-81 | 64.91% (228) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1846|M.bovis_AF2122/97 -----MCQTCRVGKRRDAREQIEAKIVELGRRQLLDHGAAGLSLRAIARN
Rv1816|M.tuberculosis_H37Rv -----MCQTCRVGKRRDAREQIEAKIVELGRRQLLDHGAAGLSLRAIARN
MAV_2899|M.avium_104 -----------MGKRQQSREQIEARIIELGRRQLVDRGAAGLSVRAIARD
Mflv_3414|M.gilvum_PYR-GCK -----------MGKRQDTRERIERDIVAIGRRHLVTEGAAGLSLRAIARD
MSMEG_3659|M.smegmatis_MC2_155 -----------MGKRQESRERIEAAIVEIGRQHLVTEGAAGLSMRAVARD
Mvan_3167|M.vanbaalenii_PYR-1 -----MCDTGRVGKRQDTRDRIERQIVEIGRAHLVTHGAAALSLRAIARE
MAB_4787c|M.abscessus_ATCC_199 MPTRTNAADVPATRRARQRAQTTDEIKALARRQLADGGTGALSLRGIARE
TH_4347|M.thermoresistible__bu ----------------VTADDIREKLVDAGVRLLERDGVQALSARNLAAE
MUL_0743|M.ulcerans_Agy99 --------MIGETTSPTQRSGVRDEMLHAAVALLDAHGPDALQTRKVAGA
MMAR_4115|M.marinum_M -----MGGRRVKPGPRDEKGVLAAQILSVARDSFAENGSAGTTVRSVARA
: . : * . * :*
Mb1846|M.bovis_AF2122/97 LGMVSSAVYRYVSSRDELLTLLLVDAYSDLADTVDRARDDTVADS--WSD
Rv1816|M.tuberculosis_H37Rv LGMVSSAVYRYVSSRDELLTLLLVDAYSDLADTVDRARDDTVADS--WSD
MAV_2899|M.avium_104 LGMVSSAVYRYVSSRDELLTLLLVDAYSDLADTVDRAR-ETAGEQ--WSD
Mflv_3414|M.gilvum_PYR-GCK LGMVSSAVYRYVASRDELLTLLLVDAYTDLADTVETARAASTGD---WRE
MSMEG_3659|M.smegmatis_MC2_155 LGMVSSAVYRYVASRDELLTLLVVDAYTELADAVAAAVADVSAAGARWRS
Mvan_3167|M.vanbaalenii_PYR-1 LGMVSSAVYRYVASRDELLTLLLVDAYGELADSVERARDAAAGD---WQD
MAB_4787c|M.abscessus_ATCC_199 MGMAPAALFRYFETQAALITALCVDANGALAQAMSDGQKAAPESD--SAA
TH_4347|M.thermoresistible__bu AGTSTMAVYTRFGGMPGVLEAVAGEIFARFADALTQIPQTGDPVA-----
MUL_0743|M.ulcerans_Agy99 TGTSTMAVYTHFGGMPELIAEVADEGLRQFDTALA-VPPSDDPVA-----
MMAR_4115|M.marinum_M ADVDPSLIYHYFGSKEGLLDAATTPPQRWLDTVAETWTTPKADLG----R
. . :: . :: :
Mb1846|M.bovis_AF2122/97 DVIAIARAVRGWAVTNPARWALLYGSPVPGYHAPPDRTAGVATRVVGAFF
Rv1816|M.tuberculosis_H37Rv DVIAIARAVRGWAVTNPARWALLYGSPVPGYHAPPDRTAGVATRVVGAFF
MAV_2899|M.avium_104 DVIAIARATRRWAVEHPACWALLYGSPVPGYHAPPERTVAAGTRVVAALF
Mflv_3414|M.gilvum_PYR-GCK QLRALGHAIRAWAVRQPASWALLYGSPVPGYHAPRDRTVTPGTRVVAALF
MSMEG_3659|M.smegmatis_MC2_155 QIRAIAHATRNWALDQPARWALLYGSPVPGYHAPAERTVVPGTRVVVALF
Mvan_3167|M.vanbaalenii_PYR-1 RLRAVAHATRAWAVHHPARWALLYGSPVPGYHAPREQTVGPGTRVVGLLF
MAB_4787c|M.abscessus_ATCC_199 RLRAAFVAARRWALAHPGDFALLSGTPIPGYAAQPAETGPAAMRVIASFM
TH_4347|M.thermoresistible__bu DFLLMGAAYREYALTHPQRYLLMFGTATPASIAGSRADLTATGEVSDRTE
MUL_0743|M.ulcerans_Agy99 DLVATGAAYRRYAIERPHMYRLMFGSTSAHGIN-APAQNVLTLTISQIEQ
MMAR_4115|M.marinum_M RLLQTLLDSWADDEIGPSLRAILLTAAHEDATRLKLRRIVESSLIGVSQL
. * :: :. :
Mb1846|M.bovis_AF2122/97 DAIAAGIATGDIRLTDDVAPQPMSS--DFEKIRQEFGFPGD---DRVVTK
Rv1816|M.tuberculosis_H37Rv DAIAAGIATGDIRLTDDVAPQPMSS--DFEKIRQEFGFPGD---DRVVTK
MAV_2899|M.avium_104 DAVAAGITTGDIRLTNDPAPQPMSS--DFERIRHEFGFPGD---DLVIAK
Mflv_3414|M.gilvum_PYR-GCK DVVSAGIAAGDIASGEHPAPQPLSG--DFDRLREQFGFAGD---DVLLGK
MSMEG_3659|M.smegmatis_MC2_155 AAVARGIAEGDIPATEETVAQPLSG--DFARLRAEFGLHVD---DATMAR
Mvan_3167|M.vanbaalenii_PYR-1 SAIAEGVAAGAVRTSKVTVPQSLSS--DFDRLRAEFEFVAD---DDVVAR
MAB_4787c|M.abscessus_ATCC_199 DAYLRAVAAGEAVPRRTRFRPSAPGPLLVAMFGEDTAPPID---PAIIGI
TH_4347|M.thermoresistible__bu WAASFEALRTMVRRMIAAGRIRDDGE---------------------AAI
MUL_0743|M.ulcerans_Agy99 RHPSFAHVVRGVRRSMLAGRITVNGGDDRNRAAAPDGLATDVLDAEIVAT
MMAR_4115|M.marinum_M DTDEDDRLTRSGLIASQLIGLAMTR---YVWQIEPIASMSD---------
Mb1846|M.bovis_AF2122/97 CFLLWAGVVGAISLEVFGQYGADMLTDPGVVFDAQTRLLVAVLAEH----
Rv1816|M.tuberculosis_H37Rv CFLLWAGVVGAISLEVFGQYGADMLTDPGVVFDAQTRLLVAVLAEH----
MAV_2899|M.avium_104 CFLLWAGVLGAISLEVFGQYGADTLTDVEAVFDAQLRLLVDVLTRH----
Mflv_3414|M.gilvum_PYR-GCK CLTLWAALIGAVGLEVFGQYGPDTFADPALAFDTQIAALTEMLCQ-----
MSMEG_3659|M.smegmatis_MC2_155 CFALWAGLIGAVSLEVFGQYGADTLTDPRQLFDLQIDSLTGALTN-----
Mvan_3167|M.vanbaalenii_PYR-1 CLVLWAALVGAISLEVFGQYGADTFADASVVFDAQMDLVIDLFCRQGAN-
MAB_4787c|M.abscessus_ATCC_199 GIFAWASITGYLAGEVFGSLG-DLVADSDALYHDHVDTVLCGMGFAGV--
TH_4347|M.thermoresistible__bu AGRLWSLIHGEVMLELAGFFGAEGHGLTKILTPMTVDMLVGLGD--DRAR
MUL_0743|M.ulcerans_Agy99 AAQFWALIHGFVMLELAGFFGDEGAAIEPVLASMTTNLLVALGDSPELAK
MMAR_4115|M.marinum_M -----SEVLAAITPNLQRYIDGDLHPTKKSPAQRPRRTRRP---------
: : . : :: . :
Mb1846|M.bovis_AF2122/97 --------------
Rv1816|M.tuberculosis_H37Rv --------------
MAV_2899|M.avium_104 --------------
Mflv_3414|M.gilvum_PYR-GCK --------------
MSMEG_3659|M.smegmatis_MC2_155 --------------
Mvan_3167|M.vanbaalenii_PYR-1 --------------
MAB_4787c|M.abscessus_ATCC_199 --------------
TH_4347|M.thermoresistible__bu VEASLTTAAEAHGR
MUL_0743|M.ulcerans_Agy99 RSQRLTTGAG----
MMAR_4115|M.marinum_M --------------