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MTGPGNRHEQRRRSTHEALRQAALKSFARKGFANVTVTELAREAGVTERTFFRHFPTKESVLFQDYETQL EWLAEALAQRPPSESLFDAVLASVAAFPHDLEVVRQAATARAELISAERIAGHLRVVQSSFARVLTDFVR ARNPQLANIDLFAEVAGSAVAAALVAAVENWGRRGCSGELGDDVTASLALIRSGLAPLA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2788 | - | - | 100% (199) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_0197 | - | 3e-27 | 37.17% (191) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_2512 | - | 1e-13 | 31.18% (186) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3860c | - | 5e-29 | 37.17% (191) | transcriptional regulatory protein TetR-family |
| M. gilvum PYR-GCK | Mflv_1676 | - | 1e-26 | 35.26% (190) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3830c | - | 5e-29 | 37.17% (191) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | MLBr_00316 | - | 4e-05 | 30.23% (129) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1379c | - | 2e-08 | 25.60% (125) | TetR family transcriptional regulator |
| M. marinum M | MMAR_2812 | - | 4e-86 | 81.41% (199) | TetR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_1420 | - | 4e-13 | 24.75% (198) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_3524 | - | 2e-12 | 28.28% (198) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2933 | - | 7e-87 | 81.91% (199) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0989 | - | 1e-76 | 73.23% (198) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2812|M.marinum_M -----------MTVPTNRHELRRRSTHEALRRAALKSFACKGFAQVTVTE
MUL_2933|M.ulcerans_Agy99 -----------MTVPTNRHELRRRSTHEALRRAALKSFARKGFAQVTVTE
MAV_2788|M.avium_104 -----------MTGPGNRHEQRRRSTHEALRQAALKSFARKGFANVTVTE
Mvan_0989|M.vanbaalenii_PYR-1 -----------MTATPSLHEQRRRSTREALRRAALASFAARGFANVTVTE
Mb3860c|M.bovis_AF2122/97 -----------MVRPP--QTARSERTREALRQAALVRFLAQGVEATSAEQ
Rv3830c|M.tuberculosis_H37Rv -----------MVRPP--QTARSERTREALRQAALVRFLAQGVEATSAEQ
Mflv_1676|M.gilvum_PYR-GCK -----------MVRPA--QTVRSERTREALRQAAVVRFLAQGVEETTAEQ
MSMEG_1420|M.smegmatis_MC2_155 ------------MSEGSRAGRRRSTTQDHIAGVAIDLFAARGFDAVSVDD
TH_3524|M.thermoresistible__bu --------------------VRGHRNREALIAAAIDLFTVNGYEQTTVEQ
MAB_1379c|M.abscessus_ATCC_199 -----------MPEQLSRFERRKQETRREILGAALACFAERGYHATGIAD
MLBr_00316|M.leprae_Br4923 MSVPRSGLSVQMAQPARPLRADAARNRARILGVAYEAFATEGLS-VPIDE
.: : .* * .* . :
MMAR_2812|M.marinum_M LAREAGVTERTFFRHFPTKEAVLFQDYENQLEWLAQA----LAQRPVSE-
MUL_2933|M.ulcerans_Agy99 LAREAGVTERTFFRHFPTKEAVLFQDYENQLEWLARA----LAQRPVSE-
MAV_2788|M.avium_104 LAREAGVTERTFFRHFPTKESVLFQDYETQLEWLAEA----LAQRPPSE-
Mvan_0989|M.vanbaalenii_PYR-1 LARAAGVTERTFFRHFPTKEAVLFQDYETQVEWLAAA----LARRPGSE-
Mb3860c|M.bovis_AF2122/97 IAEDAGVSLRTFYRHFRSKHDLLFADYDAGLHWFRAA----LDARPADE-
Rv3830c|M.tuberculosis_H37Rv IAEDAGVSLRTFYRHFRSKHDLLFADYDAGLHWFRAA----LDARPADE-
Mflv_1676|M.gilvum_PYR-GCK IAADAGVSLRTFYRHFASKHDLLFADYDAGLHWFRAA----LATRSPED-
MSMEG_1420|M.smegmatis_MC2_155 VAAAAGISRRTLFRYYASKSAIPWGDFDSHLQHLQNL----LRTLSSEV-
TH_3524|M.thermoresistible__bu IAEAAGVAPRTFFRHFAAKEDILFHGYADRLAEATRR----FRAARSG--
MAB_1379c|M.abscessus_ATCC_199 IVRRVGIAQGTFYLYFQSKREIVEQILDDLMERLSAA----LLDLPPSAP
MLBr_00316|M.leprae_Br4923 IARRAGVGAGTVYRHFPTKEALCAAVIGDRMPHLVDDGYVLLKSAGPGE-
:. .*: *.: :: :* : : :
MMAR_2812|M.marinum_M -PLFDAVLASVAAFP-HDLEVVRQAATARSELISADRIANHLRVVQSSFA
MUL_2933|M.ulcerans_Agy99 -PLFDAVLASVAAFP-HDLEVVRQAATARSELISADRIANHLRVVQSSFA
MAV_2788|M.avium_104 -SLFDAVLASVAAFP-HDLEVVRQAATARAELISAERIAGHLRVVQSSFA
Mvan_0989|M.vanbaalenii_PYR-1 -SVFDAVRAAIAEFP-YDLEVVRQAATARSELISAERIAGHLRVVQSSFA
Mb3860c|M.bovis_AF2122/97 -SIIDSVQAAIFSFP-YDVDAVTKIASLRRGELEPSRIVRHMREVEADFA
Rv3830c|M.tuberculosis_H37Rv -SIIDSVQAAIFSFP-YDVDAVTKIASLRRGELEPSRIVRHMREVEADFA
Mflv_1676|M.gilvum_PYR-GCK -PILDTVQAAIMAAP-YDDWAVTKIAAMRSQELDAGRIVRHIRQVEADFA
MSMEG_1420|M.smegmatis_MC2_155 -SLGDALREALLTFNTYADHEMAEHRQRMRVILETEELQAYSMTMYAGWR
TH_3524|M.thermoresistible__bu -SLWKALAEASEAVATAIAENPGIFLVRARMYGELPALRATMLRINDDWI
MAB_1379c|M.abscessus_ATCC_199 TSLAEYRDQAEHISTSLTGVLSADPQAARFLLLQAAAVDDDMAERVLAFY
MLBr_00316|M.leprae_Br4923 -ALFTYLRSLVLHWGATDRGLVDALAGAG-----GIDILGVAPDAEDAFL
.: : :
MMAR_2812|M.marinum_M QVLTAFVRDR-----YADVANVDLVAEVAGATIAAALVVAVENW--GRNG
MUL_2933|M.ulcerans_Agy99 QVLTAFVRNR-----YADVANVDLVAEVAGATIAAALVVAVENW--GRYG
MAV_2788|M.avium_104 RVLTDFVRAR-----NPQLANIDLFAEVAGSAVAAALVAAVENW--GRRG
Mvan_0989|M.vanbaalenii_PYR-1 DVLTGHIRTR-----YAGTADIDLVADVAGAALAAALVVAVEHW--GRNG
Mb3860c|M.bovis_AF2122/97 DAIQAQLRRRNCD--IAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDR
Rv3830c|M.tuberculosis_H37Rv DAIQAQLRRRNCD--IAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDR
Mflv_1676|M.gilvum_PYR-GCK DAIDEHLARADGA--SPGT-DERMRTTVTARCIAAAVFGAMEVWMLGEDS
MSMEG_1420|M.smegmatis_MC2_155 TVIAEYVADR------LGMSTTDLMPQTVAWLMLGVALSAYENW---LAD
TH_3524|M.thermoresistible__bu DQMTTEVARWLG-----SDAAVDVRPRLAATVINGANRTAIDLW--VSAD
MAB_1379c|M.abscessus_ATCC_199 DAAAAIQATYLQHGISAGYFRSDLDAGHAARAVNGMLLASAFYS--LRDP
MLBr_00316|M.leprae_Br4923 TILSDLLYAAQ----YAGTARTDVGVREVKSILVGCQAMEAYNS------
: . : .
MMAR_2812|M.marinum_M CAVDLGELVAASLDLVRSGLAPLS----------------
MUL_2933|M.ulcerans_Agy99 CAEDLGELVAASLDLVRSGLAPLS----------------
MAV_2788|M.avium_104 CSGELGDDVTASLALIRSGLAPLA----------------
Mvan_0989|M.vanbaalenii_PYR-1 CVDDLGEITSASMAVLRSGFARLT----------------
Mb3860c|M.bovis_AF2122/97 SLGELARVCHVALESLRVGISDTWTTLTVSS---------
Rv3830c|M.tuberculosis_H37Rv SLGELARVCHVALESLRVGISDTWTTLTVSS---------
Mflv_1676|M.gilvum_PYR-GCK SLPELDRLCRHALDLLRTGIADPA----------------
MSMEG_1420|M.smegmatis_MC2_155 ESVSLRGAIAAAFEVARPGLDALQPAH-------------
TH_3524|M.thermoresistible__bu GKGDLVELMADAVRLVRPTLDRIERESRTVANPVRRRDVV
MAB_1379c|M.abscessus_ATCC_199 SPAAFEQLAHAVREILYYGLASDHHPQIAD----------
MLBr_00316|M.leprae_Br4923 ------ALAERVTDVVVDGLRAAR----------------
: