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MVRPAQTARSERTREALRQAALVRFLAQGVEDTSAEQIAADAGVSLRTFYRHFRSKHDLLFADYTGLHWF RAALDARPADEPIIDSVQAAIFSFPYDVDAVTKIAALRHEELDPGRIVRHIRDVQADFAEAIAAQLQRRG RGAGAPTADQRVRAAVTARCIAAAVFGAMEVWMVGDERSLGELARLCHAALESLRAGITDSWSTATAPQV SS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0197 | - | - | 100% (212) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_2788 | - | 3e-27 | 37.17% (191) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_2657 | - | 3e-12 | 29.86% (211) | transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3860c | - | 7e-90 | 81.25% (208) | transcriptional regulatory protein TetR-family |
| M. gilvum PYR-GCK | Mflv_1676 | - | 2e-75 | 72.14% (201) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3830c | - | 7e-90 | 81.25% (208) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0248c | - | 4e-07 | 28.67% (143) | TetR family transcriptional regulator |
| M. marinum M | MMAR_5384 | - | 2e-91 | 79.07% (215) | TetR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_1648 | - | 3e-08 | 34.03% (144) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_3524 | - | 5e-11 | 30.93% (194) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_5004 | - | 1e-90 | 78.60% (215) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5077 | - | 2e-76 | 73.63% (201) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1676|M.gilvum_PYR-GCK MVRPAQTVRSERTRE---ALRQAAVVRFLAQG-VEETTAEQIAADAGVSL
Mvan_5077|M.vanbaalenii_PYR-1 MVRPAQTARSERTRE---ALRQAAVVRFLAQG-VEDTSAEQIAADAGVSL
Mb3860c|M.bovis_AF2122/97 MVRPPQTARSERTRE---ALRQAALVRFLAQG-VEATSAEQIAEDAGVSL
Rv3830c|M.tuberculosis_H37Rv MVRPPQTARSERTRE---ALRQAALVRFLAQG-VEATSAEQIAEDAGVSL
MAV_0197|M.avium_104 MVRPAQTARSERTRE---ALRQAALVRFLAQG-VEDTSAEQIAADAGVSL
MMAR_5384|M.marinum_M MVRPAQTVRSERTRE---ALRQAAVVRFLAQG-VEETSAEQIAADAGVSL
MUL_5004|M.ulcerans_Agy99 MVRPAQTVRSERTRE---ALRQAAVVRFLAQG-VEETSAEQIAADAGVSL
TH_3524|M.thermoresistible__bu -------VRGHRNRE---ALIAAAIDLFTVNG-YEQTTVEQIAEAAGVAP
MAB_0248c|M.abscessus_ATCC_199 -MRPASGLREQKKSETKLALSRAALELALDRGDLAAVTVDDIADAVRVSA
MSMEG_1648|M.smegmatis_MC2_155 -----MGLRERKKLDTRRALSDAALHLMFKRGGLENVTREDIAAMAGVSV
* .:. : ** **: .* .: ::** . *:
Mflv_1676|M.gilvum_PYR-GCK RTFYRHFASKHDLLFADYDAGLHWFRAALATRSPEDPILDTVQAAIMAAP
Mvan_5077|M.vanbaalenii_PYR-1 RTFYRHFASKHDLLFADYDAGLHWFRSALAARSPEESIFESVQSAIMASP
Mb3860c|M.bovis_AF2122/97 RTFYRHFRSKHDLLFADYDAGLHWFRAALDARPADESIIDSVQAAIFSFP
Rv3830c|M.tuberculosis_H37Rv RTFYRHFRSKHDLLFADYDAGLHWFRAALDARPADESIIDSVQAAIFSFP
MAV_0197|M.avium_104 RTFYRHFRSKHDLLFADY-TGLHWFRAALDARPADEPIIDSVQAAIFSFP
MMAR_5384|M.marinum_M RTFYRHFRSKHDLLFADY-TGLHWFRAALDARPVDETIIDSVQTAIFAFP
MUL_5004|M.ulcerans_Agy99 RTFYRHFRSKHDLLFADY-TGLHWFRAALDARPVDEAIIDSVQTAIFAFP
TH_3524|M.thermoresistible__bu RTFFRHFAAKEDILFHGYADRLAEATRRFRAARSG-SLWKALAEASEAVA
MAB_0248c|M.abscessus_ATCC_199 RTFRNYFTSKEDAVLFSLRGIEDNAVALLRQRPQHEHVVDSLEAVMLDLA
MSMEG_1648|M.smegmatis_MC2_155 RTFNNYFTGKYEALAYRQTERMRRSIELLRERPADEPLWTAITEAVIAPL
*** .:* .* : : : : :: .
Mflv_1676|M.gilvum_PYR-GCK YDDWA----VTKIAAMRSQELDAGRIVR--HIRQVEAD-FADAIDEHLAR
Mvan_5077|M.vanbaalenii_PYR-1 YEDWA----VTKIAAMRAKELDTGRIVR--HIRQVEAD-FAEAVEQHMAA
Mb3860c|M.bovis_AF2122/97 YDVDA----VTKIASLRRGELEPSRIVR--HMREVEAD-FADAIQAQLRR
Rv3830c|M.tuberculosis_H37Rv YDVDA----VTKIASLRRGELEPSRIVR--HMREVEAD-FADAIQAQLRR
MAV_0197|M.avium_104 YDVDA----VTKIAALRHEELDPGRIVR--HIRDVQAD-FAEAIAAQLQR
MMAR_5384|M.marinum_M YDVEA----VAKIATLRGGELDPSRIVR--HIQEVQAD-FAEVIAAQLRR
MUL_5004|M.ulcerans_Agy99 YDVEA----VAKIATLRGGELDPSRIVR--HIQEVQAD-FAEVIAAQLLR
TH_3524|M.thermoresistible__bu TAIAE----NPGIFLVRARMYGELPALRA-TMLRINDD-WIDQMTTEVAR
MAB_0248c|M.abscessus_ATCC_199 TSEAF----STTVAVTRLSAQNPG--LAA-HDAARSED-VGTVVLTEVSR
MSMEG_1648|M.smegmatis_MC2_155 QEDMDDVYGQENALPTRRQLVEVRKILTIPQIRDVTFRGMFDEWVAVIAE
* : :
Mflv_1676|M.gilvum_PYR-GCK ADGASPGTD-----ERMRTTVTARCIAAAVFGAMEVWMLGEDSS-----L
Mvan_5077|M.vanbaalenii_PYR-1 AGAAAPGTD-----ERMRTTVTARCIAAAVFGAMEVWMLGEDRS-----L
Mb3860c|M.bovis_AF2122/97 RNCDIAGAP----DARLHIAVTARCVAAAVFGAMEAWMLGSDRS-----L
Rv3830c|M.tuberculosis_H37Rv RNCDIAGAP----DARLHIAVTARCVAAAVFGAMEAWMLGSDRS-----L
MAV_0197|M.avium_104 RGRG-AGAPTA--DQRVRAAVTARCIAAAVFGAMEVWMVGDERS-----L
MMAR_5384|M.marinum_M RSCAAAGTSAQTPDARVRTAVTARCIAAAVFGAMEVWMLGEDRS-----L
MUL_5004|M.ulcerans_Agy99 RSCAAAGTSAQTPDARVRTAVTARCIAAAVFGAMEVWMLGEDRS-----L
TH_3524|M.thermoresistible__bu WLGSDAAVD-------VRPRLAATVINGANRTAIDLWVSADGKGDLVELM
MAB_0248c|M.abscessus_ATCC_199 RAGLDPDVD-------LYPRLVCNAAYAVLATVIQLAVSGSKLS------
MSMEG_1648|M.smegmatis_MC2_155 RTGTDPGDR--------YPRLVAAVVRAVGDVAMDEYAGADPPV------
. :.. .. .:: ..
Mflv_1676|M.gilvum_PYR-GCK PELDRLCRHALDLLRTGIADPA----------
Mvan_5077|M.vanbaalenii_PYR-1 PELDRLCRQALTLLRSGIEDPVG---------
Mb3860c|M.bovis_AF2122/97 GELARVCHVALESLRVGISDTWTTLT---VSS
Rv3830c|M.tuberculosis_H37Rv GELARVCHVALESLRVGISDTWTTLT---VSS
MAV_0197|M.avium_104 GELARLCHAALESLRAGITDSWSTATAPQVSS
MMAR_5384|M.marinum_M GELARVCQLALETLRAGLTNTWCPDRPRTVSS
MUL_5004|M.ulcerans_Agy99 GELARVCQLALETSRAGLTNTWCPDRPRTVSS
TH_3524|M.thermoresistible__bu ADAVRLVRPTLDRIERESRTVANPVRRRDVV-
MAB_0248c|M.abscessus_ATCC_199 KDPGALVAQGFQRLRDGLA-------------
MSMEG_1648|M.smegmatis_MC2_155 -SFPSLLREGFAAVAAGLPEPKARV-------
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