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VPDDHPPTGLRQRKKADTRRALSDAALALAFERGLDNVTREDIANVAGVSLRTFNNYFTGKYEALAYRQT ERMRRSIAALRERPAGEPLWTAIAHAVLEPLQADLHEATADEDRLPSRGELAEVRKLLMNPQIREAASRE LLEDWRDAIAERTGTDPENDMYPRLVVAVVRAVGDAAMDTYATADPPVAITELIRAGFASVAAGLPEPAK PGEQRG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2714 | - | - | 100% (216) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_2933 | - | 1e-09 | 25.50% (200) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_3793 | - | 8e-09 | 27.53% (178) | putative regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3860c | - | 4e-09 | 31.25% (144) | transcriptional regulatory protein TetR-family |
| M. gilvum PYR-GCK | Mflv_1728 | - | 2e-13 | 31.22% (221) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3830c | - | 4e-09 | 31.25% (144) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0248c | - | 3e-19 | 32.20% (205) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3438 | - | 1e-121 | 100.00% (216) | TetR family transcriptional regulator |
| M. avium 104 | MAV_2512 | - | 2e-13 | 31.28% (195) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1648 | - | 5e-74 | 70.15% (201) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_3524 | - | 2e-11 | 28.33% (180) | PUTATIVE - |
| M. vanbaalenii PYR-1 | Mvan_5023 | - | 9e-12 | 30.24% (205) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_2714|M.ulcerans_Agy99 --MPDDHPPTGLRQRKKADTRRALSDAALALAFERG-LDNVTREDIANVA
MMAR_3438|M.marinum_M --MPDDHPPTGLRQRKKADTRRALSDAALALAFERG-LDNVTREDIANVA
MSMEG_1648|M.smegmatis_MC2_155 ---------MGLRERKKLDTRRALSDAALHLMFKRGGLENVTREDIAAMA
Mflv_1728|M.gilvum_PYR-GCK MAEPRGEPVLGLRERKKRRTRATLIDAAMGLCDRQG-FDATTVDQIAAIA
Mvan_5023|M.vanbaalenii_PYR-1 -----------MRERKKRRTRATLIDAAVGLCDRQG-YDATTVDQIAHVA
Mb3860c|M.bovis_AF2122/97 -------MVRPPQTARSERTREALRQAALVRFLAQG-VEATSAEQIAEDA
Rv3830c|M.tuberculosis_H37Rv -------MVRPPQTARSERTREALRQAALVRFLAQG-VEATSAEQIAEDA
MAB_0248c|M.abscessus_ATCC_199 -----MRPASGLREQKKSETKLALSRAALELALDRGDLAAVTVDDIADAV
MAV_2512|M.avium_104 -----MANPVGLRERRRRQTSADIRDAAVRLTLERG-FDKVTVDEICAEA
TH_3524|M.thermoresistible__bu --------------VRGHRNREALIAAAIDLFTVNG-YEQTTVEQIAEAA
: . : **: .* .: ::*. .
MUL_2714|M.ulcerans_Agy99 GVSLRTFNNYFTGKYEALAYRQTERMRRSIAALRERPAGEPLWTAIAHAV
MMAR_3438|M.marinum_M GVSLRTFNNYFTGKYEALAYRQTERMRRSIAALRERPAGEPLWTAIAHAV
MSMEG_1648|M.smegmatis_MC2_155 GVSVRTFNNYFTGKYEALAYRQTERMRRSIELLRERPADEPLWTAITEAV
Mflv_1728|M.gilvum_PYR-GCK EVSPRTFSRYFATKDAIALALIDEVLDSAAAELARQPLDIGNFEALRRAY
Mvan_5023|M.vanbaalenii_PYR-1 EVSPRTFSRYFATKDAIALALIDEVLVHTAVELVRQPRYLPHMEALRRAY
Mb3860c|M.bovis_AF2122/97 GVSLRTFYRHFRSKHDLLFADYDAGLHWFRAALDARPADESIIDSVQAAI
Rv3830c|M.tuberculosis_H37Rv GVSLRTFYRHFRSKHDLLFADYDAGLHWFRAALDARPADESIIDSVQAAI
MAB_0248c|M.abscessus_ATCC_199 RVSARTFRNYFTSKEDAVLFSLRGIEDNAVALLRQRPQHEHVVDSLEAVM
MAV_2512|M.avium_104 GISTRTFFNYFPNKESAIAYGPSDIPPELVADFVAAG--PAPYSVVLAEL
TH_3524|M.thermoresistible__bu GVAPRTFFRHFAAKEDILFHGYADRLAEATRRFRAARS-GSLWKALAEAS
:: *** .:* * : :
MUL_2714|M.ulcerans_Agy99 LEPLQADLHEATADEDRLPSRGELAEVRKLLMNPQIREAASRELLEDWRD
MMAR_3438|M.marinum_M LEPLQADLHEATADEDRLPSRGELAEVRKLLMNPQIREAASRELLEDWRD
MSMEG_1648|M.smegmatis_MC2_155 IAPLQEDMDDVYGQENALPTRRQLVEVRKILTIPQIRDVTFRGMFDEWVA
Mflv_1728|M.gilvum_PYR-GCK IAMARNTKLAAAG---ALTSERMLQILRIVMSSGTLRQATVEYRASKVDR
Mvan_5023|M.vanbaalenii_PYR-1 VAMAEASKLAPPG---ALSAQRLLQILRIIVSSPTLRQAAVGYRAGPVDA
Mb3860c|M.bovis_AF2122/97 FSFPYDVDAVTKI---ASLRRGELEPSRIVRHMREVEADFADAIQAQLRR
Rv3830c|M.tuberculosis_H37Rv FSFPYDVDAVTKI---ASLRRGELEPSRIVRHMREVEADFADAIQAQLRR
MAB_0248c|M.abscessus_ATCC_199 LDLATSEAFSTTVAVTRLSAQN--------PGLAAHDAARSEDVGTVVLT
MAV_2512|M.avium_104 IALAAHHLRDVPPR--REHAANMLELAKTSPAVLAAFLADLERFQNQLTD
TH_3524|M.thermoresistible__bu EAVATAIAENPGIFLVRARMYG------ELPALRATMLRINDDWIDQMTT
MUL_2714|M.ulcerans_Agy99 AIAERTGTDPENDMYPRLVVAVVRAVGDAAMDTYAT-------ADPPVAI
MMAR_3438|M.marinum_M AIAERTGTDPENDMYPRLVVAVVRAVGDAAMDTYAT-------ADPPVAI
MSMEG_1648|M.smegmatis_MC2_155 VIAERTGTDP-GDRYPRLVAAVVRAVGDVAMDEYAG-------ADPPVSF
Mflv_1728|M.gilvum_PYR-GCK LLAERMGTSV-HDRRVKLLAAVWGAVLITAMDDLARKHVSGISVDDVISA
Mvan_5023|M.vanbaalenii_PYR-1 VVAERMGATV-DDRRVKLVAAVWGVVLMTALQDVCRSAVD-FGVDDVIAA
Mb3860c|M.bovis_AF2122/97 RNCDIAGAPD-ARLHIAVTARCVAAAVFGAMEAWMLG-----SDRSLGEL
Rv3830c|M.tuberculosis_H37Rv RNCDIAGAPD-ARLHIAVTARCVAAAVFGAMEAWMLG-----SDRSLGEL
MAB_0248c|M.abscessus_ATCC_199 EVSRRAGLDPDVDLYPRLVCNAAYAVLATVIQLAVSG------SKLSKDP
MAV_2512|M.avium_104 IIVRRQGMQP-DDEMAPLISALALTAVRSGIEKWASG-----EASETDDT
TH_3524|M.thermoresistible__bu EVARWLGSDAAVDVRPRLAATVINGANRTAIDLWVSADGKGDLVELMADA
* : . ::
MUL_2714|M.ulcerans_Agy99 TELIRAGFASVAAGLPEPAKPGEQRG--
MMAR_3438|M.marinum_M TELIRAGFASVAAGLPEPAKPGEQRG--
MSMEG_1648|M.smegmatis_MC2_155 PSLLREGFAAVAAGLPEPKARV------
Mflv_1728|M.gilvum_PYR-GCK FDDTYAEFAGEIAGIGQPV---------
Mvan_5023|M.vanbaalenii_PYR-1 VEATYAEFAGEIAGVVQPV---------
Mb3860c|M.bovis_AF2122/97 ARVCHVALESLRVGISDTWTTLTVSS--
Rv3830c|M.tuberculosis_H37Rv ARVCHVALESLRVGISDTWTTLTVSS--
MAB_0248c|M.abscessus_ATCC_199 GALVAQGFQRLRDGLA------------
MAV_2512|M.avium_104 PMPYVERAAALVNSIFTK----------
TH_3524|M.thermoresistible__bu VRLVRPTLDRIERESRTVANPVRRRDVV