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TPESLRDRQRAQIRADIRRAAFRLFVERGYDAVTTEEIATAAGVSPRTFFRHVPAKEELLLAPVRYGGAA IVHLLEGRPAGESPDVALINAIITRTRSFEPADTEEWRQALLVAPGLLDKVTVHRPADKERATKLIADRM RVDPHTDIRPGLLVQLAFAAADFGFQQWVLQSGRRWPLDRYVAEALKAVKSPHWRRK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0350 | - | - | 100% (198) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_2391 | - | 3e-31 | 41.40% (186) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_2512 | - | 3e-15 | 32.16% (171) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3860c | - | 7e-09 | 31.18% (170) | transcriptional regulatory protein TetR-family |
| M. gilvum PYR-GCK | Mflv_0350 | - | 2e-12 | 33.33% (171) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3830c | - | 7e-09 | 31.18% (170) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | MLBr_00815 | - | 2e-05 | 25.69% (144) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0248c | - | 5e-08 | 29.52% (166) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3861 | - | 9e-34 | 46.39% (166) | putative regulatory protein |
| M. smegmatis MC2 155 | MSMEG_5673 | - | 4e-09 | 30.00% (150) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_3524 | - | 7e-09 | 60.98% (41) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3793 | - | 1e-31 | 45.18% (166) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_1156 | - | 2e-13 | 54.10% (61) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3861|M.marinum_M ----------------MASEGDGMNPANIGSLRDRRRAELFSLIQQTAHR
MUL_3793|M.ulcerans_Agy99 ----------------MASEGDGMSPANIGSLRDRRRAELFSLIQQTAHR
MAV_0350|M.avium_104 -----------------------MTPE---SLRDRQRAQIRADIRRAAFR
Mb3860c|M.bovis_AF2122/97 -----------------------MVRPPQTARSER----TREALRQAALV
Rv3830c|M.tuberculosis_H37Rv -----------------------MVRPPQTARSER----TREALRQAALV
Mflv_0350|M.gilvum_PYR-GCK ---------------------MEGMNPEQPGLRERKKTRTRETVRREAFR
Mvan_1156|M.vanbaalenii_PYR-1 ---------------------MSGHDRPQS-LRERKKVRTRLAIRREAFR
MSMEG_5673|M.smegmatis_MC2_155 ----------------------MAYQTQQPGLRERKKQRTRATLISAAID
TH_3524|M.thermoresistible__bu ----------------------------------VRGHRNREALIAAAID
MAB_0248c|M.abscessus_ATCC_199 -------------------------MRPASGLREQKKSETKLALSRAALE
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
: *
MMAR_3861|M.marinum_M LFAERG-FDAVTTEDIAAAAGVSISTYFRHAPTKEGLLVDPVRQAITEIV
MUL_3793|M.ulcerans_Agy99 LFAERG-FDAVTTEDIAAAAGVSISTYFRHAPTKEGLLVDPVRQAITEIV
MAV_0350|M.avium_104 LFVERG-YDAVTTEEIATAAGVSPRTFFRHVPAKEELLLAPVRYGGAAIV
Mb3860c|M.bovis_AF2122/97 RFLAQG-VEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGLHWFR
Rv3830c|M.tuberculosis_H37Rv RFLAQG-VEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGLHWFR
Mflv_0350|M.gilvum_PYR-GCK LFELNG-YAQTTVDQIAEAAFVSPRTFFRYFPTKESVLFS--DDLFNPII
Mvan_1156|M.vanbaalenii_PYR-1 LFAKQG-YANTTVEQIAEAADVSPRTFYRYFGVKERLLIS--DDKISPIV
MSMEG_5673|M.smegmatis_MC2_155 LCVRQG-YEQTTVEQIAAAAEVSARTFSRYFATKDAVMLAFLDDVVDLVA
TH_3524|M.thermoresistible__bu LFTVNG-YEQTTVEQIAEAAGVAPRTFFRHFAAKEDILFHGYADRLAEAT
MAB_0248c|M.abscessus_ATCC_199 LALDRGDLAAVTVDDIADAVRVSARTFRNYFTSKEDAVLFSLRGIEDNAV
MLBr_00815|M.leprae_Br4923 VFVDHG-YHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLV
.* . ::** . *: . .: * .
MMAR_3861|M.marinum_M SSYRSWPADESAVEALIALFVSYARDAGDLKLDTWRRAIATAPYLLSKSA
MUL_3793|M.ulcerans_Agy99 SSYRSWPADESAVEASIALFVSYARDAGDLKLDTLRRAIATAPYLLSKSA
MAV_0350|M.avium_104 HLLEGRPAGESPDVALINAIITRTRSFEPADTEEWRQALLVAPGLLDKVT
Mb3860c|M.bovis_AF2122/97 AALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVRHM
Rv3830c|M.tuberculosis_H37Rv AALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVRHM
Mflv_0350|M.gilvum_PYR-GCK EEFLAAPAELSPVAAYRHAAARV-FETMAGSDYDYIIARQRLLYDLPEAK
Mvan_1156|M.vanbaalenii_PYR-1 EAFIAAPKELPIVPAYRHAVGTV-FDGLTQEERDDFVAGEQMMYAIPEAR
MSMEG_5673|M.smegmatis_MC2_155 GELAQQPPELGELDAVFCAHITAFEKTRVAMPGQLTDDRLLAAARIFTSS
TH_3524|M.thermoresistible__bu RRFRAARSGSLWKALAEASEAVATAIAENPGIFLVRARMYGELPALRATM
MAB_0248c|M.abscessus_ATCC_199 ALLRQRPQHEHVVDSLEAVMLDLATSEAFSTTVAVTRLSAQNPG-LAAHD
MLBr_00815|M.leprae_Br4923 SSVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDNITEPRVA
MMAR_3861|M.marinum_M LVSEDDQHRFIEHVASRMG-VDARTDIRPALLVHTSLATVKFVFDRWLST
MUL_3793|M.ulcerans_Agy99 LVSEDDQHRFIEHVASRMG-VDARTDIRPALLVHTSLATVKFVFDRWLST
MAV_0350|M.avium_104 VHRPADKERATKLIADRMR-VDPHTDIRPGLLVQLAFAAADFGFQQWVLQ
Mb3860c|M.bovis_AF2122/97 REVEADFADAIQAQLRRRN-CDIAGAPDARLHIAVTARCVAAAVFGAMEA
Rv3830c|M.tuberculosis_H37Rv REVEADFADAIQAQLRRRN-CDIAGAPDARLHIAVTARCVAAAVFGAMEA
Mflv_0350|M.gilvum_PYR-GCK GALWNEHVGAIR-RLTSAI-AKRLGRPEDDYQARVTAGAIIGVFMAASDD
Mvan_1156|M.vanbaalenii_PYR-1 GLVYTEYVRLID-LIADAL-TDRPDGPTDEMERRVVAGAIVGVLIAASHN
MSMEG_5673|M.smegmatis_MC2_155 PSLMQATMGFRPAPLFEVL-AKRMGVSADDRKIALIASLWNAIMTTALVQ
TH_3524|M.thermoresistible__bu LRINDDWIDQMTTEVARWLGSDAAVDVRPRLAATVINGANRTAIDLWVSA
MAB_0248c|M.abscessus_ATCC_199 AARSEDVGTVVLTEVSRRAGLDPDVDLYPRLVCNAAYAVLATVIQLAVSG
MLBr_00815|M.leprae_Br4923 AQVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGISVDCARYWLDT
.
MMAR_3861|M.marinum_M DPPSSPIFHVQMDQ------------------------------------
MUL_3793|M.ulcerans_Agy99 DPPSSPIFHVQWTRRCGSRSPDSGNAIRHLPSSRETEPNFVVRHDIWVRP
MAV_0350|M.avium_104 SGRRWPLDRYVAEA------------------------------------
Mb3860c|M.bovis_AF2122/97 WMLGSDRSLGELAR------------------------------------
Rv3830c|M.tuberculosis_H37Rv WMLGSDRSLGELAR------------------------------------
Mflv_0350|M.gilvum_PYR-GCK EPMSGEAFLEALDL------------------------------------
Mvan_1156|M.vanbaalenii_PYR-1 NPFPEDVLLRSLEI------------------------------------
MSMEG_5673|M.smegmatis_MC2_155 LVPDVDWATVTVER------------------------------------
TH_3524|M.thermoresistible__bu DGKGDLVELMADAVRLVR--------------------------------
MAB_0248c|M.abscessus_ATCC_199 SKLSKDPGALVAQG------------------------------------
MLBr_00815|M.leprae_Br4923 NRPISKSDAVEGTVQFAWG-------------------------------
MMAR_3861|M.marinum_M -----ALRIALAGFR---------------
MUL_3793|M.ulcerans_Agy99 SGSGSNPRASACSFERMRPCIHHRRHHCTR
MAV_0350|M.avium_104 ------LKAVKSPHWRRK------------
Mb3860c|M.bovis_AF2122/97 ------VCHVALESLRVGISDTWTTLTVSS
Rv3830c|M.tuberculosis_H37Rv ------VCHVALESLRVGISDTWTTLTVSS
Mflv_0350|M.gilvum_PYR-GCK ------LDQALPR-----------------
Mvan_1156|M.vanbaalenii_PYR-1 ------LGRRLT------------------
MSMEG_5673|M.smegmatis_MC2_155 -----IVNQMRTTYAEFLEVAGRRHEFA--
TH_3524|M.thermoresistible__bu ----PTLDRIERESRTVANPVRRRDVV---
MAB_0248c|M.abscessus_ATCC_199 ------FQRLRDGLA---------------
MLBr_00815|M.leprae_Br4923 -----GLSHVPLTRL---------------