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ASEGDGMNPANIGSLRDRRRAELFSLIQQTAHRLFAERGFDAVTTEDIAAAAGVSISTYFRHAPTKEGLL VDPVRQAITEIVSSYRSWPADESAVEALIALFVSYARDAGDLKLDTWRRAIATAPYLLSKSALVSEDDQH RFIEHVASRMGVDARTDIRPALLVHTSLATVKFVFDRWLSTDPPSSPIFHVQMDQALRIALAGFR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3861 | - | - | 100% (206) | putative regulatory protein |
| M. marinum M | MMAR_4840 | - | 9e-67 | 63.37% (202) | putative regulatory protein |
| M. marinum M | MMAR_3853 | - | 2e-09 | 38.78% (98) | putative regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2534 | - | 9e-10 | 38.24% (102) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2551 | - | 6e-11 | 37.27% (110) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2506 | - | 9e-10 | 38.24% (102) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 4e-06 | 23.86% (176) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0248c | - | 8e-10 | 28.40% (169) | TetR family transcriptional regulator |
| M. avium 104 | MAV_2391 | - | 1e-69 | 67.84% (199) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1420 | - | 2e-10 | 28.98% (176) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_3524 | - | 2e-10 | 28.40% (162) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3793 | - | 1e-104 | 98.45% (193) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0989 | - | 2e-10 | 31.90% (116) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2534|M.bovis_AF2122/97 ------------MTASAPDGRPGQPEATNRRSQ--LKSDRRFQLLAAAER
Rv2506|M.tuberculosis_H37Rv ------------MTASAPDGRPGQPEATNRRSQ--LKSDRRFQLLAAAER
Mflv_2551|M.gilvum_PYR-GCK ---------------MAP------TEISSPRSR--AKSDRRDQLVAAAER
MMAR_3861|M.marinum_M --------------MASEGDGMNPANIGSLRDR--RRAELFSLIQQTAHR
MUL_3793|M.ulcerans_Agy99 --------------MASEGDGMSPANIGSLRDR--RRAELFSLIQQTAHR
MAV_2391|M.avium_104 ---------------------MPSANSSSLRDR--RRAELLSQIQQTAHQ
MSMEG_1420|M.smegmatis_MC2_155 ------------------------MSEGSRAGR--RRSTTQDHIAGVAID
TH_3524|M.thermoresistible__bu -----------------------------VRGH--RNRE---ALIAAAID
Mvan_0989|M.vanbaalenii_PYR-1 -----------------------MTATPSLHEQ--RRRSTREALRRAALA
MAB_0248c|M.abscessus_ATCC_199 -----------------------MRPASGLREQ--KKSETKLALSRAALE
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
. . : .*
Mb2534|M.bovis_AF2122/97 LFAERG-FLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVSARLL
Rv2506|M.tuberculosis_H37Rv LFAERG-FLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVSARLL
Mflv_2551|M.gilvum_PYR-GCK LFAEHG-YLAVRLEDIGSAAGISGPAVYRHFPNKEALLVELLVGISTRLL
MMAR_3861|M.marinum_M LFAERG-FDAVTTEDIAAAAGVSISTYFRHAPTKEGLLVDPVRQAITEIV
MUL_3793|M.ulcerans_Agy99 LFAERG-FDAVTTEDIAAAAGVSISTYFRHAPTKEGLLVDPVRQAITEIV
MAV_2391|M.avium_104 LFAERG-FEAVTTEDIAAAAGISISTYFRYAPTKEGLLVDPAREVAATIV
MSMEG_1420|M.smegmatis_MC2_155 LFAARG-FDAVSVDDVAAAAGISRRTLFRYYASKSAIPWGDFDSHLQHLQ
TH_3524|M.thermoresistible__bu LFTVNG-YEQTTVEQIAEAAGVAPRTFFRHFAAKEDILFHGYADRLAEAT
Mvan_0989|M.vanbaalenii_PYR-1 SFAARG-FANVTVTELARAAGVTERTFFRHFPTKEAVLFQDYETQVEWLA
MAB_0248c|M.abscessus_ATCC_199 LALDRGDLAAVTVDDIADAVRVSARTFRNYFTSKEDAVLFSLRGIEDNAV
MLBr_00815|M.leprae_Br4923 VFVDHG-YHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLV
.* . ::. . :: . .: . *
Mb2534|M.bovis_AF2122/97 AGARDVTTRSANLAAALDGLIEFHLDFALGEADL--IRIQDRDLAHLPAV
Rv2506|M.tuberculosis_H37Rv AGARDVTTRSANLAAALDGLIEFHLDFALGEADL--IRIQDRDLAHLPAV
Mflv_2551|M.gilvum_PYR-GCK AGATDVVGADDDAASTLENLIDFHLDFALDESDL--IRIQDRDLGNLPPA
MMAR_3861|M.marinum_M SSYRSWPADES----AVEALIALFVSYARDAGDL-KLDTWRRAIATAPYL
MUL_3793|M.ulcerans_Agy99 SSYRSWPADES----AVEASIALFVSYARDAGDL-KLDTLRRAIATAPYL
MAV_2391|M.avium_104 GAYRTRPAHES----AVEALIQLFVTHAKEVGAAGDFDTWRHAVATAPHL
MSMEG_1420|M.smegmatis_MC2_155 NLLRTLSSEVSLGDALREALLTFNTYADHEMAEH---RQRMRVILETEEL
TH_3524|M.thermoresistible__bu RRFR-AARSGSLWKALAEASEAVATAIAENPGIF---LVRARMYGELPAL
Mvan_0989|M.vanbaalenii_PYR-1 AALARRPGSES----VFDAVRAAIAEFPYDLEVVRQAATARSELISAERI
MAB_0248c|M.abscessus_ATCC_199 ALLRQRPQHEH----VVDSLEAVMLDLATSEAFS-TTVAVTRLSAQNPGL
MLBr_00815|M.leprae_Br4923 SSVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQG-YRLIFENDNITEPRV
.
Mb2534|M.bovis_AF2122/97 AERQVRKAQRQYVEVWVGVLRELNP-GLAEADARLMAHAVFGLLNSTPHS
Rv2506|M.tuberculosis_H37Rv AERQVRKAQRQYVEVWVGVLRELNP-GLAEADARLMAHAVFGLLNSTPHS
Mflv_2551|M.gilvum_PYR-GCK AKRQVRRKQRQYVEIWVDVLRRCTP-GLSEADARLMAHGTFGLLNSTAHS
MMAR_3861|M.marinum_M LSKSALVSEDDQHRFIEHVASRMGVDARTDIRPALLVHTSLATVKFVFDR
MUL_3793|M.ulcerans_Agy99 LSKSALVSEDDQHRFIEHVASRMGVDARTDIRPALLVHTSLATVKFVFDR
MAV_2391|M.avium_104 LRKSVLMSETDHSNLIQQVAARMNVTAALDIRPALLVHTSLATVQFVLDG
MSMEG_1420|M.smegmatis_MC2_155 QAYSMTMYAGWRTVIAEYVADRLGM-STTDLMPQTVAWLMLGVALSAYEN
TH_3524|M.thermoresistible__bu RATMLRINDDWIDQMTTEVARWLGSDAAVDVRPRLAATVINGANRTAIDL
Mvan_0989|M.vanbaalenii_PYR-1 AGHLRVVQSSFADVLTGHIRTRYAGTADIDLVADVAGAALAAALVVAVEH
MAB_0248c|M.abscessus_ATCC_199 AAHDAARSEDVGTVVLTEVSRRAGLDPDVDLYPRLVCNAAYAVLATVIQL
MLBr_00815|M.leprae_Br4923 AAQVRVATESCIDAVFALIS---ADSRLDPHRARMVAVGLVGISVDCARY
. : . .
Mb2534|M.bovis_AF2122/97 MKAADSKPARTVRARAVLR-------------------------------
Rv2506|M.tuberculosis_H37Rv MKAADSKPARTVRARAVLR-------------------------------
Mflv_2551|M.gilvum_PYR-GCK MKPGTTKTAEAG-SRTVLR-------------------------------
MMAR_3861|M.marinum_M WLSTDPPSSPIFHVQMDQ--------------------------------
MUL_3793|M.ulcerans_Agy99 WLSTDPPSSPIFHVQWTRRCGSRSPDSGNAIRHLPSSRETEPNFVVRHDI
MAV_2391|M.avium_104 WLSSDSDESRPFHEQLEE--------------------------------
MSMEG_1420|M.smegmatis_MC2_155 WLADESVSLRGAIAAAFE--------------------------------
TH_3524|M.thermoresistible__bu WVSADGKGDLVELMADAVR-------------------------------
Mvan_0989|M.vanbaalenii_PYR-1 WGRNGCVDDLGEITSASMA-------------------------------
MAB_0248c|M.abscessus_ATCC_199 AVSGSKLSKDPG--------------------------------------
MLBr_00815|M.leprae_Br4923 WLDTNRPISKSDAVEGTVQ-------------------------------
Mb2534|M.bovis_AF2122/97 -----------AMTVAALSAADRCL-------------
Rv2506|M.tuberculosis_H37Rv -----------AMTVAALSAADRCL-------------
Mflv_2551|M.gilvum_PYR-GCK -----------EMTVAALTSAERRRG------------
MMAR_3861|M.marinum_M ---------ALRIALAGFR-------------------
MUL_3793|M.ulcerans_Agy99 WVRPSGSGSNPRASACSFERMRPCIHHRRHHCTR----
MAV_2391|M.avium_104 ---------ALRITLAGFDRPSDATPGRR---------
MSMEG_1420|M.smegmatis_MC2_155 ------------VARPGLDALQPAH-------------
TH_3524|M.thermoresistible__bu ------------LVRPTLDRIERESRTVANPVRRRDVV
Mvan_0989|M.vanbaalenii_PYR-1 ------------VLRSGFARLT----------------
MAB_0248c|M.abscessus_ATCC_199 -----------ALVAQGFQRLRDGLA------------
MLBr_00815|M.leprae_Br4923 ------------FAWGGLSHVPLTRL------------
: