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MRIAVTGASGVLGRGLAARLLSKGHDVVGIARHRPDSWSSAADFIEADIRDAAAVNRAVTSADVVAHFAW THDTQERTGSQVNIAGTANVLAAMAETSARRIVFPSSPHVYGGGDTPRSEAEAPAPSAADAVQQARVEEM LVASGLESVTIRCALVVGRNVDNWVRRVLALPAFPGGTVDRPIQLVHLDDALRLLESAVLSHEIPSGTVN LAAPGTTTFRRIAATLRRPVLRLGRPAPAELEPVLSAPLMDTALLHERWGFRPAWQCGECVEDMALAVRG RVTVGRRVVSLPWRLANVADLPAVDAPAQDGVVPVPAGPEGVNGEFDTPIDPRFPTFLATNLSEALPGPF SPSSASATVRGVRAGGVTIAERLRPGGLVQREIALRTVGVFAHRLYGAITSAHFMAETVPFAKPSMIVSN SGFFGPSMASLPVFGEQRPAETGWARRLLRNTRNIGVFGVNLVGLSSGAARDTDDFIADVDRLERLAGDA AELDERRLLSLIALARDQVVHGWVLASASFMLCAAFNVLLRAVCGRDTSAPAGPELVSARSVEAMQRLVV AAQRDPNVARVLTEPGERLDKLAVDAPEFHAAVLAELALIGHRGPAELEMLSTSYADDPELLVRMVAKAM AATAAPPPQHPRIPLQAKLIAALTARQLRDREARRDKVVRANWVLRALLREYGRRLTHAGVFGSADDVFY LLVDELDALPADVAAVVARRRAEHRRLAGIAPPTVFSGSWQPTATSVPALAGGGTLRGVGVCGGRVRGRV RIVRPETIDDLQPGEILVAEATDVGYTAAFCYAAAVVTELGGPMSHAAVVAREFGFPCVVDVQGATKSLP PGALVEVDGATGEIRVLELASEPATGGG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2451 | - | - | 100% (868) | hypothetical protein MAV_2451 |
| M. avium 104 | MAV_2850 | - | 3e-65 | 30.40% (750) | hypothetical protein MAV_2850 |
| M. avium 104 | MAV_5056 | - | 3e-34 | 26.25% (560) | PEP-utilizing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2073c | - | 0.0 | 73.32% (877) | hypothetical protein Mb2073c |
| M. gilvum PYR-GCK | Mflv_0493 | - | 3e-37 | 30.77% (572) | pyruvate, water dikinase |
| M. tuberculosis H37Rv | Rv2047c | - | 0.0 | 73.32% (877) | hypothetical protein Rv2047c |
| M. leprae Br4923 | MLBr_02428 | - | 4e-10 | 27.73% (321) | putative glucose epimerase/dehydratase |
| M. abscessus ATCC 19977 | MAB_4003c | - | 5e-10 | 30.30% (264) | putative UDP-glucose 4-epimerase GalE1 |
| M. marinum M | MMAR_3024 | - | 0.0 | 72.94% (872) | hypothetical protein MMAR_3024 |
| M. smegmatis MC2 155 | MSMEG_3934 | - | 7e-18 | 43.55% (124) | phosphoenolpyruvate synthase |
| M. thermoresistible (build 8) | TH_4555 | - | 5e-26 | 30.10% (299) | PUTATIVE putative phosphoenolpyruvate synthase |
| M. ulcerans Agy99 | MUL_2265 | - | 0.0 | 72.36% (872) | hypothetical protein MUL_2265 |
| M. vanbaalenii PYR-1 | Mvan_2632 | - | 6e-27 | 29.54% (413) | pyruvate, water dikinase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2073c|M.bovis_AF2122/97 ---------------MRIAVTGASGVLGRGLTARLLSQGHEVVGIARHRP
Rv2047c|M.tuberculosis_H37Rv ---------------MRIAVTGASGVLGRGLTARLLSQGHEVVGIARHRP
MMAR_3024|M.marinum_M ---------------MRVAVTGAGGVLGRGLASRLLSQGHEVVGMSRRRP
MUL_2265|M.ulcerans_Agy99 ---------------MRVAVTGAGGVLGRGLASRLLSQGHEVVGMSRRRP
MAV_2451|M.avium_104 ---------------MRIAVTGASGVLGRGLAARLLSKGHDVVGIARHRP
MLBr_02428|M.leprae_Br4923 --------------------------------------------------
MAB_4003c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_2632|M.vanbaalenii_PYR-1 -----------------MTGTMIHWLTDAGAADPSRSGGKGAKLALLVRA
Mflv_0493|M.gilvum_PYR-GCK ------------------MFDASSRIVDLADVLDDSFGGKALGLAELTRL
TH_4555|M.thermoresistible__bu MMTDMSAVTSPNTVEAEHTVSNVIRFADPGATDPRLVGGKGMNLGELVAA
MSMEG_3934|M.smegmatis_MC2_155 --------------MDIMSDRYVRTLDILTIADAEEAGGKGANLGELVAA
Mb2073c|M.bovis_AF2122/97 DSWPSSADFIAADIRDATAVESAMTGADVVAHCAWVRGR------NDHIN
Rv2047c|M.tuberculosis_H37Rv DSWPSSADFIAADIRDATAVESAMTGADVVAHCAWVRGR------NDHIN
MMAR_3024|M.marinum_M DSWPSQADFVAGDIRDAAAVRRAITGADVVAHCAWARNPGPDGRISQQIN
MUL_2265|M.ulcerans_Agy99 DSWPSQADFVAGDIRDAAAVRRAITGADVVAHCAWARNPGPDGRISQQIN
MAV_2451|M.avium_104 DSWSSAADFIEADIRDAAAVNRAVTSADVVAHFAWTHDT--QERTGSQVN
MLBr_02428|M.leprae_Br4923 --------------------------------------------------
MAB_4003c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_2632|M.vanbaalenii_PYR-1 GLPVPAGFVVLTEAYRRFVSDHGLDGLIRQQLGAINTGP-----------
Mflv_0493|M.gilvum_PYR-GCK GLPVPPGFVIADAS---------GTSLGDAVTERFSR-------------
TH_4555|M.thermoresistible__bu GFRVPNGFTVSTEAYAATLADSGAADRIFELLKGLDVAD-----------
MSMEG_3934|M.smegmatis_MC2_155 DLPVPHGFVVMRSAYLDSVRMGGVEAELAALHTEALTHA-----------
Mb2073c|M.bovis_AF2122/97 IDGTANVLKAMAETGTGRIVFTSS-------------------------G
Rv2047c|M.tuberculosis_H37Rv IDGTANVLKAMAETGTGRIVFTSS-------------------------G
MMAR_3024|M.marinum_M IDGTRNVLDAMAACGTGRIVFPSSPHVYRPGVPMPATEHGAVAPASAEGR
MUL_2265|M.ulcerans_Agy99 IDGTRNVLDAMAACGTGRIVFPSSPHVYRPGLPMPATEHGAVAPASAEGR
MAV_2451|M.avium_104 IAGTANVLAAMAETSARRIVFPSSPHVYGGG-DTPRSEAEAPAPSAADAV
MLBr_02428|M.leprae_Br4923 --------------------------------------------------
MAB_4003c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_2632|M.vanbaalenii_PYR-1 -DGDPDVVHAVSARLRAAFESAP-----------------------MSEE
Mflv_0493|M.gilvum_PYR-GCK --------------------------------------------------
TH_4555|M.thermoresistible__bu ----LARLESTAAAIRDVVTAVELP----------------------DKL
MSMEG_3934|M.smegmatis_MC2_155 --ADTARLSELCRRMQSLVNKAGLS----------------------PSV
Mb2073c|M.bovis_AF2122/97 HQPRVEQMLADCGLEWVAVRCALIFGRNVDNWVQRLFALPVLPAGYADRV
Rv2047c|M.tuberculosis_H37Rv HQPRVEQMLADCGLEWVAVRCALIFGRNVDNWVQRLFALPVLPAGYADRV
MMAR_3024|M.marinum_M HKAGVEQMLQESGAQWVAVRSALIVGRNIDNWVRRLFALPAFPDGSADDV
MUL_2265|M.ulcerans_Agy99 HKAGVEQMLQESGAQWVAVRSALIVGRNIDNWVRRLFALPAFPDGSADDV
MAV_2451|M.avium_104 QQARVEEMLVASGLESVTIRCALVVGRNVDNWVRRVLALPAFPGGTVDRP
MLBr_02428|M.leprae_Br4923 --------------------------------------------------
MAB_4003c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_2632|M.vanbaalenii_PYR-1 LRDQVAAAHSTLGAAASAVRSSATAEDLPEASFAGQQDTFLNIVGAEALC
Mflv_0493|M.gilvum_PYR-GCK --------MRAAGQTPVAVRSSAAGEDGAEHSFAGQYDTVLGVGSVDELT
TH_4555|M.thermoresistible__bu AHDIERAYTELGADVYVAVRSSGTAEDTAEASFAGMHDTYLDIRGTGEVL
MSMEG_3934|M.smegmatis_MC2_155 RDATLAAYRALGTDVVVAVRSSATGEDGRDASFAGMNRTITNVMGEVALL
Mb2073c|M.bovis_AF2122/97 VQVVHSDDAQRLLVRALLDTVIDSGPVNLAAPGELTFRRIAAALGRPMVP
Rv2047c|M.tuberculosis_H37Rv VQVVHSDDAQRLLVRALLDTVIDSGPVNLAAPGELTFRRIAAALGRPMVP
MMAR_3024|M.marinum_M LQVVHLDDVLRLLTRAVSDVGAGTGPVNLAAPGLPTLREIAMALRRPILP
MUL_2265|M.ulcerans_Agy99 LQVVHLDDVLRLLTRAVSDVGAGTGPVNLAAPGLPTLREIATALRRPILP
MAV_2451|M.avium_104 IQLVHLDDALRLLESAVLSHEIPSGTVNLAAPGTTTFRRIAATLRRPVLR
MLBr_02428|M.leprae_Br4923 -------------------MDSSSGQDGGGTGGVVPYPKVVLVTGACRFL
MAB_4003c|M.abscessus_ATCC_199 ---------------------MSAGESN------LHYPRVVLVTGASRFL
Mvan_2632|M.vanbaalenii_PYR-1 EAIKRCWSSLWSARAIAYRRDNDIGHEDIS-IAVVVQSMVPATVAGVLFT
Mflv_0493|M.gilvum_PYR-GCK AAVEKCVRSAGSERAAAYQDGGAAARMH-----LVVQQMVDARAAGVVFT
TH_4555|M.thermoresistible__bu DAVRRCWASMWTARAVAYREEHGFDHREAK-IAVVVQTMAEADVSGVMYT
MSMEG_3934|M.smegmatis_MC2_155 DAVTQCWMSLFSPRVITYR--ASRGFTAAPAMAVVVQQMLSADRAGVAFT
Mb2073c|M.bovis_AF2122/97 IGSPVLRRVTSFAELELLHSAPLMDVTLLRDRWGFQPAWN-AEECLEDFT
Rv2047c|M.tuberculosis_H37Rv IGSPVLRRVTSFAELELLHSAPLMDVTLLRDRWGFQPAWN-AEECLEDFT
MMAR_3024|M.marinum_M VG-AVLRRIGSVAEFQLVQGVPVMDTARLHDEWKFQPAFT-AEESVEDFA
MUL_2265|M.ulcerans_Agy99 VG-AALRRIGSVAEFQLVQGVPVMDTARLHDEWKFQPAFT-AEESVEDFA
MAV_2451|M.avium_104 LG------RPAPAELEPVLSAPLMDTALLHERWGFRPAWQ-CGECVEDMA
MLBr_02428|M.leprae_Br4923 GG-------------------------YLTARLAQNPLIN-AVIAVDAIA
MAB_4003c|M.abscessus_ATCC_199 GG-------------------------YLAARLVQNPMIN-RVIAVDAVA
Mvan_2632|M.vanbaalenii_PYR-1 ADPISGRRDRIVIEAAAEPGEAVVGGGMTPDRWVLDAVTR-RPIDAPERA
Mflv_0493|M.gilvum_PYR-GCK ADPTSGRRDLLVIDAVRGLGESLVDGSTASDHFVLTHAGDTVTTEASSQP
TH_4555|M.thermoresistible__bu ANPLNNRTDEIVINSAYGLGESIVSGAINPDEFTVDLGTLKIKQANVGNK
MSMEG_3934|M.smegmatis_MC2_155 SDPSTGDADHIVIEAAFGQGEVVVSGKVEPDTYVIDKRTLEVRDVRIGFK
.
Mb2073c|M.bovis_AF2122/97 LAVRGRIGLGKRTFSLPWRLANIQDLPAVDSPADDGVAPRLAGPEGANGE
Rv2047c|M.tuberculosis_H37Rv LAVRGRIGLGKRTFSLPWRLANIQDLPAVDSPADDGVAPRLAGPEGANGE
MMAR_3024|M.marinum_M LAVRGRVSLGRRVVSLPWRLANIQDLPAVDAPAQDGVVPRLAGPEGVNGE
MUL_2265|M.ulcerans_Agy99 LAVRGRVSLGRRVVSLPWRLANIQDLPAIDASAQDGVVPRLAGPEGVNGE
MAV_2451|M.avium_104 LAVRGRVTVGRRVVSLPWRLANVADLPAVDAPAQDGVVPVPAGPEGVNGE
MLBr_02428|M.leprae_Br4923 PSKD--------------MLRRMGHAEFVRADIRNPFIAKVIR----NGE
MAB_4003c|M.abscessus_ATCC_199 PSKD--------------LLRRMGRAEFVRADIRNPFIAKVIR----NGE
Mvan_2632|M.vanbaalenii_PYR-1 LLTSEQLDSLVDLGARATAAFGIPQDLEWAVDDDGRCWLLQSRPITSLFP
Mflv_0493|M.gilvum_PYR-GCK ALADDEIDRIRTGALLAAAHWGRPLDLEWAIDRDGLLWWLQARPITTLPG
TH_4555|M.thermoresistible__bu KEKIVRAPDKPSGTVTLAVSEEDAGRLSLTDEQVAELAALGRQVMDHYGG
MSMEG_3934|M.smegmatis_MC2_155 AIKIVRGD---DGADSMVQLERSQAEARVLDDDALRKIATLAVATETHNG
Mb2073c|M.bovis_AF2122/97 FDTPIDPRFPT----YLATNLSEALPGPFSPSSASVTVRGLRAGGVGIAE
Rv2047c|M.tuberculosis_H37Rv FDTPIDPRFPT----YLATNLSEALPGPFSPSSASVTVRGLRAGGVGIAE
MMAR_3024|M.marinum_M FDTPIDPRFPT----FLATNLSEALPGPFSPSSASVTVRGLRAGGVGIAE
MUL_2265|M.ulcerans_Agy99 FDTPIDPRFPT----FLATNLSEALPGPFSPSSASVTVRGLRAGGVGIAE
MAV_2451|M.avium_104 FDTPIDPRFPT----FLATNLSEALPGPFSPSSASATVRGVRAGGVTIAE
MLBr_02428|M.leprae_Br4923 VDTVVHADAAS----YAPR-----------------------SCGSAALK
MAB_4003c|M.abscessus_ATCC_199 VDTVVHTASAS----YSPR-----------------------SGGRAALK
Mvan_2632|M.vanbaalenii_PYR-1 IPPATRPGLRV----YLPVMLIAQG-----------IAEPMTPSGNAFFR
Mflv_0493|M.gilvum_PYR-GCK DPNEMDTPVTG----PTHVYTRCN-------------IGEMMPGAFCPLT
TH_4555|M.thermoresistible__bu LPQDIEWACVDGEFFLLQTRPITGAKFTWPEGFNDWQNGPEDPDTLWTFK
MSMEG_3934|M.smegmatis_MC2_155 CPQDIEWVIADGAVWLVQARPITTLG-------SAGSTAGDEPSVLIRGL
.
Mb2073c|M.bovis_AF2122/97 RLRPSGVIQREIAMRTV-AVFAHRLYGAITSAHFMAATVPFAKP----AT
Rv2047c|M.tuberculosis_H37Rv RLRPSGVIQREIAMRTV-AVFAHRLYGAITSAHFMAATVPFAKP----AT
MMAR_3024|M.marinum_M RLRPGGVIQREIAMRTV-AVFAHRLYGAITSAHFMAETVPFAKP----AM
MUL_2265|M.ulcerans_Agy99 RLRPGGVIQREIAMRTV-AVFAHRLYGAITSAHFMAETVPFAKP----AM
MAV_2451|M.avium_104 RLRPGGLVQREIALRTV-GVFAHRLYGAITSAHFMAETVPFAKP----SM
MLBr_02428|M.leprae_Br4923 ELN---------VMGAM-QLFAA------------CQKAPTVRR----VV
MAB_4003c|M.abscessus_ATCC_199 ELN---------VMGAM-QLFAA------------CQKAPTVQR----VV
Mvan_2632|M.vanbaalenii_PYR-1 TMVGGWFRYWISGRRPR-ASDADPDWMPIVADRLFLDVTPVLQRPRLAAR
Mflv_0493|M.gilvum_PYR-GCK ASVSGHAIDYAMQMVQV-AGGVQERYEDRARQVGYFFGHMFLNMT--EGT
TH_4555|M.thermoresistible__bu YAEQYWTGGITPLFFSVRARETQVGYDRMNARAGFQDLLGQRLYKDKYGT
MSMEG_3934|M.smegmatis_MC2_155 PAAPGVASGRVRVLLAPDDGDKLTDGEILVAPTTNPDWLPTIRR----AA
Mb2073c|M.bovis_AF2122/97 IVSNSGFFGPS-MASLPIFGA---------QRPPSESSRARRWLRTLRNI
Rv2047c|M.tuberculosis_H37Rv IVSNSGFFGPS-MASLPIFGA---------QRPPSESSRARRWLRTLRNI
MMAR_3024|M.marinum_M IVSNSGFFGPS-MGSLPIFGE---------ERPPAESSFVRRQLRTVRNI
MUL_2265|M.ulcerans_Agy99 IVSNSGFFGPS-MGSLPIFGE---------ERPPAESSFVRRQLCTVRNI
MAV_2451|M.avium_104 IVSNSGFFGPS-MASLPVFGE---------QRP-AETGWARRLLRNTRNI
MLBr_02428|M.leprae_Br4923 LKSTSAVYGSG-SRDPVMFTE---------DSSSWRSF--------REGF
MAB_4003c|M.abscessus_ATCC_199 VKSTAQVYGAS-ARDPVMFTE---------EMSARRPP--------ADGF
Mvan_2632|M.vanbaalenii_PYR-1 VLSNFGMKDPAGSAALRKWLSQN---SGRLPRPDRAAPPRGLLVLLPSLL
Mflv_0493|M.gilvum_PYR-GCK ALSSGILGNSLEQFSLSVCGR------VIDELEPGPPKPFVRKLINTVRL
TH_4555|M.thermoresistible__bu VYWNVDMDEKRLRYVLPRFARPAGANVVPADMQEQMFAEPLDVVRWLKAM
MSMEG_3934|M.smegmatis_MC2_155 ALVTETGGMTCHAAIVARELG----------VPCVVGARSATVALAVGSM
. :
Mb2073c|M.bovis_AF2122/97 GVFGVNLVGLSAGSPRDT-------DAYVADVDRLERLAFDNLATHDDRR
Rv2047c|M.tuberculosis_H37Rv GVFGVNLVGLSAGSPRDT-------DAYVADVDRLERLAFDNLATHDDRR
MMAR_3024|M.marinum_M GVFGVNLVGLSAGSALDT-------NDFIADVDRLEQLAGGDVTTLDDRR
MUL_2265|M.ulcerans_Agy99 GVFGVNLVGLSAGSALDT-------NDFIADVDRLEQLAGGDVTTLDDRR
MAV_2451|M.avium_104 GVFGVNLVGLSSGAARDT-------DDFIADVDRLERLAG-DAAELDERR
MLBr_02428|M.leprae_Br4923 AKDSLDIEGYARGLGRRR-------SDIAVTILRLADMIGPAMDTTLSRY
MAB_4003c|M.abscessus_ATCC_199 ARDSIDIESYARGLGRRR-------PDVAVTILRLANLIGPGMDTALARY
Mvan_2632|M.vanbaalenii_PYR-1 AGTVASIAAPTRARRRIV-------AGADAELARLEQQAEMLSAPDEQLR
Mflv_0493|M.gilvum_PYR-GCK STFALSSAPAIRRLPQTI-------AAFPPITSRDPAVVLRHLEAGVDIY
TH_4555|M.thermoresistible__bu ISFSVSPIYSLSRWKKVIREDYLFNEAAVAKANGLSDAELRALSDDELYR
MSMEG_3934|M.smegmatis_MC2_155 VTVDGTRGEVTTGRLPET------VRTTTTPQEPAPHITGEATGTKVYVN
Mb2073c|M.bovis_AF2122/97 LLS--LILLARDHVVHGWVLASGSFMLCAAFNVLLRGLCGRDTAP--AAG
Rv2047c|M.tuberculosis_H37Rv LLS--LILLARDHVVHGWVLASGSFMLCAAFNVLLRGLCGRDTAP--AAG
MMAR_3024|M.marinum_M LLS--LILLARDHVVHGWVLASGSFMLCAAFNVLLRAVSGRDTAP--AAG
MUL_2265|M.ulcerans_Agy99 LLS--LILLARDHVVHGWVLASGSFMLCAAFNVLLRAVSGRDTAP--AAG
MAV_2451|M.avium_104 LLS--LIALARDQVVHGWVLASASFMLCAAFNVLLRAVCGRDTSA--PAG
MLBr_02428|M.leprae_Br4923 LAG--PLVPTMCGRDARLQLLHEQDALGALECAAMTGKAGTFNIG--ASG
MAB_4003c|M.abscessus_ATCC_199 LAG--PVVPTMLGRDARLQLLHEQDALGALERATMAGKAGTFNIA--ADG
Mvan_2632|M.vanbaalenii_PYR-1 FVERELPAATCDMVLRQLAAAYGEWLLRVVIERLVRRWLGSSTGF--APV
Mflv_0493|M.gilvum_PYR-GCK REVT-LIHVRSSSRSAVAANVLESHLVRRAAKRGASDTAGSAEAIRLMTG
TH_4555|M.thermoresistible__bu YQRDLQEYAIDFMDPLWFGAYTAMSMFFSLHAALLAKYYTGTNELLGQDL
MSMEG_3934|M.smegmatis_MC2_155 LAMPDSAEAVAAQDVDGVGLLRAEFMLTEALAGRHPRDLITKGEQ-----
.
Mb2073c|M.bovis_AF2122/97 PELVSARSVEAVQRLVAAARRDPVVIRLLAEPGER-------LDKLAVEA
Rv2047c|M.tuberculosis_H37Rv PELVSARSVEAVQRLVAAARRDPVVIRLLAEPGER-------LDKLAVEA
MMAR_3024|M.marinum_M PELVSARSVEAVQRLVAAARHDEAVIRLLSEPGDR-------LGKLAVAA
MUL_2265|M.ulcerans_Agy99 PELVSARSVEAVQRLVDAARHDEAVIRLLSEPGDR-------LGKLAVAA
MAV_2451|M.avium_104 PELVSARSVEAMQRLVVAAQRDPNVARVLTEPGER-------LDKLAVDA
MLBr_02428|M.leprae_Br4923 -------------------------IMMLSQAIRR-------AGRIAVPI
MAB_4003c|M.abscessus_ATCC_199 -------------------------MMMMSQAVRR-------SGQLGIPV
Mvan_2632|M.vanbaalenii_PYR-1 LRWLPHDPTIAMGAALARLAREHAAAGIEPGPESAGV--SEFLATFGHRA
Mflv_0493|M.gilvum_PYR-GCK AGVESALMVEELTAVVSMLRRDGDAAARFLAAPAG------EAVTRLRAA
TH_4555|M.thermoresistible__bu ISGLPTTLQALENRAFFELTSMIRHSKVLSDAFEKHQGAAFFAELENSDE
MSMEG_3934|M.smegmatis_MC2_155 ----------------------DTLVDAMAAAVTR-------IGTAFAPR
.
Mb2073c|M.bovis_AF2122/97 PEFHSAV-LAELTLIGHRGPAEVEMAATSYADNPELLVRMVAKTLRAVPA
Rv2047c|M.tuberculosis_H37Rv PEFHSAV-LAELTLIGHRGPAEVEMAATSYADNPELLVRMVAKTLRAVPA
MMAR_3024|M.marinum_M PHFYDAV-RQELSLIGHRGPAEVEMMSTSYADNPELLVGMVAKTLSTSSV
MUL_2265|M.ulcerans_Agy99 PHFYDAV-RQELSLIGHRGPAEVEMMSTSYADNPELLVGMVAKTLSTSSV
MAV_2451|M.avium_104 PEFHAAV-LAELALIGHRGPAELEMLSTSYADDPELLVRMVAKAMAATAA
MLBr_02428|M.leprae_Br4923 PSFGVWA-LDLLRWV------------NRYTEIT----------------
MAB_4003c|M.abscessus_ATCC_199 PSFAVAA-IASFTKG------------TRYTELS----------------
Mvan_2632|M.vanbaalenii_PYR-1 PDREVDLGLPRLSDDPTYVVELINGYLRSGALDTFETGVHEARAASDGLI
Mflv_0493|M.gilvum_PYR-GCK ETPSGAALRTFLDRHGHRGYRELCMRDPSWADDPDGLGAMMQVMLRGAAP
TH_4555|M.thermoresistible__bu GREFLEKYREFLAEHGHRGHPDRDLIFKRRADDPAVDYEAFKVQLQAPEA
MSMEG_3934|M.smegmatis_MC2_155 PVIYRAMDFRTNEFRGLAGGEQFEPVEHNPMIGYRGCYR-----------
Mb2073c|M.bovis_AF2122/97 -----------------------PQPPTPVIPLRAKPVALLAARQLRDRE
Rv2047c|M.tuberculosis_H37Rv -----------------------PQPPTPVIPLRAKPVALLAARQLRDRE
MMAR_3024|M.marinum_M -----------------------PQPPQPSIPLQAKPIAVLAARQLRDRE
MUL_2265|M.ulcerans_Agy99 -----------------------PQPPQPSIPLQAKPIAVLAARQLRDRE
MAV_2451|M.avium_104 -----------------------PPPQHPRIPLQAKLIAALTARQLRDRE
MLBr_02428|M.leprae_Br4923 ---------------------------------RDQFEYLSYGRVMDTTR
MAB_4003c|M.abscessus_ATCC_199 ---------------------------------SEQRDWLAYGRAMDNTR
Mvan_2632|M.vanbaalenii_PYR-1 -----------------------TGVRRVKGPVRAAVLRNLLARHLALGG
Mflv_0493|M.gilvum_PYR-GCK E---------------------NPAATAPSDPAQSRTLRVLARLAQAGAR
TH_4555|M.thermoresistible__bu TPPIELEERVRARREAAEAEVIENLGRGFLGPVKQQLFKLLQHQIIDFLV
MSMEG_3934|M.smegmatis_MC2_155 ---------------------------------YIKEPDLFALELSALAR
Mb2073c|M.bovis_AF2122/97 VRRDR---MVRAIWVLRALLREYGRRLTEAGVFDTPDDVFYLLVDEIDAL
Rv2047c|M.tuberculosis_H37Rv VRRDR---MVRAIWVLRALLREYGRRLTEAGVFDTPDDVFYLLVDEIDAL
MMAR_3024|M.marinum_M ARRDK---MVRAIWVLRALLREHGRRLAEAGVLHASDDVFYLLVDELDAL
MUL_2265|M.ulcerans_Agy99 ARRDK---MVRAIWVLRALLREHGRRLAEAGVLHASDDVFYLLVDEVDAL
MAV_2451|M.avium_104 ARRDK---VVRANWVLRALLREYGRRLTHAGVFGSADDVFYLLVDELDAL
MLBr_02428|M.leprae_Br4923 MGSEL---GYHPKWTTAGAFDDYVR-------------------------
MAB_4003c|M.abscessus_ATCC_199 MKTEL---GYQPKWTTIGAFGDYVR-------------------------
Mvan_2632|M.vanbaalenii_PYR-1 LRERPKFDMVRAMALGRRTLRRCGAALVERGLLDDADDVFFLDGADVRAA
Mflv_0493|M.gilvum_PYR-GCK GREETKSRMALMAHLLKRGYRHLGEVLHEAGRLPDADLVFFFDRRELPLV
TH_4555|M.thermoresistible__bu LRDDWRHFIDRITYAKRKAFLEVARRCVERGRLEKEDDAFFLGETELFEV
MSMEG_3934|M.smegmatis_MC2_155 AREHTPNIHLMIPFVRTRWELEECLALVDASPLRRHRNLHRWVMAEVPSV
Mb2073c|M.bovis_AF2122/97 PADVSGLVARRRAEQR--------RLAGIVPPTVFSGSWEPSPSSAAALA
Rv2047c|M.tuberculosis_H37Rv PADVSGLVARRRAEQR--------RLAGIVPPTVFSGSWEPSPSSAAALA
MMAR_3024|M.marinum_M PADVAELVARRRAEQR--------RLTAVVPPTVFSGKWEPSTASAAALT
MUL_2265|M.ulcerans_Agy99 PADVAELVARRRAEQR--------RLTAVVPPTVFSGKWEPSTASAAALT
MAV_2451|M.avium_104 PADVAAVVARRRAEHR--------RLAGIAPPTVFSGSWQPTATSVPALA
MLBr_02428|M.leprae_Br4923 --------------------------------------------------
MAB_4003c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_2632|M.vanbaalenii_PYR-1 LAGRACDLRARAAADHRSF-RRELRRRRVPRVLTSEGEAVYGFDTATPGA
Mflv_0493|M.gilvum_PYR-GCK VSGDDVTELVHRARQRR-----EALPFQAALEFGDVSVGRPTPIVRAAVS
TH_4555|M.thermoresistible__bu LNGTAKQPLVQAKIAARRPDFELFESRTFTPPMFMRGETPVDEAAPAAVA
MSMEG_3934|M.smegmatis_MC2_155 VHWLPEYVG---------------------------------------MG
Mb2073c|M.bovis_AF2122/97 AGDTLRGVGVCGGRVRGRVRIVRPETID-DLQPGEILVAEVTDVGYTAAF
Rv2047c|M.tuberculosis_H37Rv AGDTLRGVGVCGGRVRGRVRIVRPETID-DLQPGEILVAEVTDVGYTAAF
MMAR_3024|M.marinum_M AGGTLRGVGVCGGRVRGRVRIVRPETID-ELEPGEILVAEVTDVGYTAAF
MUL_2265|M.ulcerans_Agy99 AEGTLRGVGVCGGRVRGRVRIVRPETID-ELEPGEILVAEVTDVGYTAAF
MAV_2451|M.avium_104 GGGTLRGVGVCGGRVRGRVRIVRPETID-DLQPGEILVAEATDVGYTAAF
MLBr_02428|M.leprae_Br4923 --------------GRGLTPIIDLHRVR-YFEGRAIALAQRWSSRN----
MAB_4003c|M.abscessus_ATCC_199 --------------GRGITPVIEPEWVR-SLGDRAVAFAQKISS------
Mvan_2632|M.vanbaalenii_PYR-1 ETDVLIGTALSPGVHVGTVRVLDSPVGA-NLQPGEVIVAASTDPGWTPLF
Mflv_0493|M.gilvum_PYR-GCK GDGVVAGRPAGHGSVEGVVRVARSVVEARDLQPGEILVAPVTDVGWTPYF
TH_4555|M.thermoresistible__bu GSGAINGVGTSAGQVEGRARVLASMTEIGTLEQGDVLVCNATDPGWSPVF
MSMEG_3934|M.smegmatis_MC2_155 IDGVSIGSNDLTQLMLGVDRDSETCAELFDESDAAVLDAISRIISTANRL
* : .
Mb2073c|M.bovis_AF2122/97 CYAAAVVTELGGPMSHAAVVAREFGFPCVVDAQGATRFLPPGALVEVDGA
Rv2047c|M.tuberculosis_H37Rv CYAAAVVTELGGPMSHAAVVAREFGFPCVVDAQGATRFLPPGALVEVDGA
MMAR_3024|M.marinum_M CYAAAVVTELGGPMSHAAVVAREFGFPCVVDAQGATRFLPPGALIEVDGT
MUL_2265|M.ulcerans_Agy99 CYAAAVVTELGGPMSHAAVVAREFGFPCVVDAQGATRFLPPGALIEVDGT
MAV_2451|M.avium_104 CYAAAVVTELGGPMSHAAVVAREFGFPCVVDVQGATKSLPPGALVEVDGA
MLBr_02428|M.leprae_Br4923 --------------------------------------------------
MAB_4003c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_2632|M.vanbaalenii_PYR-1 LLAGALVMEVGGVMSHGALVAREYGLPAVAGIGNAMTRLRSGQRVRVDGT
Mflv_0493|M.gilvum_PYR-GCK AVIAALVTDIGSSVSHGAVVAREYGLPCVVNTLVGTQVLRTGDRVRVDGD
TH_4555|M.thermoresistible__bu GVISGLIIETGGMLAHGACLSREHGIPAVQIVG-ATQIIPDGAYVRINGT
MSMEG_3934|M.smegmatis_MC2_155 GITSSLCGQAPSTRPEFAEHLVRMGITSVSVNPDAAGAAR--RAVAAAER
Mb2073c|M.bovis_AF2122/97 TGEIHVVELASEDGPALPGSDLSR---------------------
Rv2047c|M.tuberculosis_H37Rv TGEIHVVELASEDGPALPGSDLSR---------------------
MMAR_3024|M.marinum_M TGEIQVLELAAEGDSSVTQSDPADLA-------------------
MUL_2265|M.ulcerans_Agy99 TGEIQVLELAAEGDSSVTQSDPADLA-------------------
MAV_2451|M.avium_104 TGEIRVLELASEPATGGG---------------------------
MLBr_02428|M.leprae_Br4923 ---------------------------------------------
MAB_4003c|M.abscessus_ATCC_199 ---------------------------------------------
Mvan_2632|M.vanbaalenii_PYR-1 AGSVTLLDSVAPDGAAEDPAPTADRAAGSGPRPAPRPRPVSPDSR
Mflv_0493|M.gilvum_PYR-GCK RGLVTVLDSP-----------------------------------
TH_4555|M.thermoresistible__bu TGLVEVLEPAPAGAA------------------------------
MSMEG_3934|M.smegmatis_MC2_155 RLLLDSVRHPRHAPTASPRNPL-----------------------