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MTSHRERGARAGASSRRDSVRGEQKLRTRTALMEAALELSRTQAFSGLSLRDVARGAGISPTAFYRHFSS LDDLGVALAEEGMRIARGIAREIRRREPATLAESMRILAEQVQENPDQLRFVVTERYTAPTEVRRAVNIE MRLLAGELAIDLARRDQMRLWDSADLTTAANLILSIAANAVAELVQPDTDTTEVVDSASNALTMAFVGLQ NWKPAQR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1589 | - | - | 100% (217) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1424c | - | 5e-34 | 40.33% (181) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3300c | - | 2e-07 | 29.84% (124) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0798 | - | 8e-07 | 29.24% (171) | hypothetical protein Mb0798 |
| M. gilvum PYR-GCK | Mflv_4816 | - | 1e-32 | 39.35% (216) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0775 | - | 8e-07 | 29.24% (171) | hypothetical protein Rv0775 |
| M. leprae Br4923 | MLBr_02457 | - | 7e-05 | 24.53% (159) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_0334 | - | 2e-29 | 39.32% (206) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5169 | - | 3e-27 | 35.92% (206) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1741 | - | 2e-30 | 39.44% (213) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_0258 | - | 3e-09 | 28.17% (142) | transcriptional repressor, TetR family protein, putative |
| M. ulcerans Agy99 | MUL_4787 | - | 2e-29 | 38.64% (220) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1626 | - | 8e-32 | 38.91% (221) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0798|M.bovis_AF2122/97 ------------------------------MGVT--------AAVTPKGE
Rv0775|M.tuberculosis_H37Rv ------------------------------MGVT--------AAVTPKGE
MMAR_0334|M.marinum_M ----------------MNERTPSSRPHRS--GRSRD-----SPSREERKE
MUL_4787|M.ulcerans_Agy99 ----------------MNERTPSSRPHRS--SRSRD-----SPSREERKE
MAV_5169|M.avium_104 -----------------------MRGSGR--ERSRE-----SQSREERKE
MSMEG_1741|M.smegmatis_MC2_155 ----------------MNRRTPSTRTRRSETSRSRD-----TLTREERKE
Mflv_4816|M.gilvum_PYR-GCK MGSRQEISAACGRFHTVNSRTPSSRRGHSSRSRSKDGNSRETLSREERKE
Mvan_1626|M.vanbaalenii_PYR-1 ----------------MNSRTPSSRSGRS-RSREKD-----TLSREERKE
MAB_1589|M.abscessus_ATCC_1997 ------------------MTSHRERGARAGASSRRD------SVRGEQKL
TH_0258|M.thermoresistible__bu -------------------------VSRADGGQRRA------SYQRARSR
MLBr_02457|M.leprae_Br4923 ------------------MAEHIPAVAVKTDGRKRR--------WHQHKV
:
Mb0798|M.bovis_AF2122/97 RRRYALVSAAAELLGEGGFEAVRHRAVARRAGLPLASTTYYFSSLDDLIA
Rv0775|M.tuberculosis_H37Rv RRRYALVSAAAELLGEGGFEAVRHRAVARRAGLPLASTTYYFSSLDDLIA
MMAR_0334|M.marinum_M ATRRAIIAAALKLVHDRSFSALSLREVTREAGIVPAAFYRHFESMEALGL
MUL_4787|M.ulcerans_Agy99 ATRRAIIAAALKLVHDRSFSALSLREVTREAGIVPAAFYRHFESMEALGL
MAV_5169|M.avium_104 ATRRAIIAAALKLLQDRSFSSLSLREVTREVGIVPAAFYRHFESMESLGL
MSMEG_1741|M.smegmatis_MC2_155 ATRRALIAAALKLLKDHSFSALSLREVTREAGIVPAAFYRHFDSMDALGL
Mflv_4816|M.gilvum_PYR-GCK ATRRAIVDAALHLLAERGFSALSLREVTREAGIVPAAFYRHFDSMEALGL
Mvan_1626|M.vanbaalenii_PYR-1 ATRRAIVAAALSLLAERSFSGLSLREVTREAGIVPAAFYRHFESMEALGL
MAB_1589|M.abscessus_ATCC_1997 RTRTALMEAALELSRTQAFSGLSLRDVARGAGISPTAFYRHFSSLDDLGV
TH_0258|M.thermoresistible__bu ETKRALVQAAMALWRTNGYANTTVADICRAAGVSRALFYFYFPAKEDILF
MLBr_02457|M.leprae_Br4923 ERRNELVDGTIDAIRRQGR-FLSMDEIAGKIGVSKTVLYRYFIDKNDLTT
: :: .: . : *: : :* : :
Mb0798|M.bovis_AF2122/97 RAVEHIGMIEVAQLRARVSALSRRRRGPETTAVVLVDLLVGEMSSPGLAE
Rv0775|M.tuberculosis_H37Rv RAVEHIGMIEVAQLRARVSALSRRRRGPETTAVVLVDLLVGEMSSPGLAE
MMAR_0334|M.marinum_M VLIDES----FRTLRDTLRGARAGRLDPNRVIESSVEILIGSVAERREHW
MUL_4787|M.ulcerans_Agy99 VLIDES----FRTLRDTLRGARAGRLDPNRVIESSVEILIGSVAERREHW
MAV_5169|M.avium_104 VLIDES----FRSLRDTLRDARAGKLDPNRVIESSVEILVASVADRREHW
MSMEG_1741|M.smegmatis_MC2_155 VLIDES----FRSLRDMLRGARAGKLDPHHVIESSAEILVSSFNERREHW
Mflv_4816|M.gilvum_PYR-GCK VLIDES----FRSLREMLRGARAGKLDPNRVIESSVDILIDGVQQRREHW
Mvan_1626|M.vanbaalenii_PYR-1 VLIDES----FRALREMLRGARAGKLDPNRVIESSVDILIDSVQQRREHW
MAB_1589|M.abscessus_ATCC_1997 ALAEEG----MRIARGIAREIR--RREPATLAES-MRILAEQVQENPDQL
TH_0258|M.thermoresistible__bu EVGLLS----TQAARRRIRSLLRGDYDVDSVIAAALRSLERSMARNPREL
MLBr_02457|M.leprae_Br4923 AVMMRFA---QTTLIPNMAAALSTNLDGFDLTREIIRVYVKTVAAEPEPY
.
Mb0798|M.bovis_AF2122/97 QLISRYERHIACTRLPDLRESMRRSLRQRAEAVAEAIERSG-----RSAQ
Rv0775|M.tuberculosis_H37Rv QLISRYERHIACTRLPDLRESMRRSLRQRAEAVAEAIERSG-----RSAQ
MMAR_0334|M.marinum_M RFIVRER----STGLSVLRYAIRTEIRLITSELATDLARFPGLNEWSTED
MUL_4787|M.ulcerans_Agy99 RFIVRER----STGLSVLRYAIRTDIRLITSELATDLARFPGLNEWSTED
MAV_5169|M.avium_104 RLIARER----NSGLSVLRYAIRTEIRLITSELATDLARFPGLHEWTTED
MSMEG_1741|M.smegmatis_MC2_155 RFIARER----SGGASALRYAIRTEIRLITSELAIDLARFPALKDWSSED
Mflv_4816|M.gilvum_PYR-GCK RFIGRER----STGVTVLRYAIRTEIRLITSELAIDLARFPALNTWSSED
Mvan_1626|M.vanbaalenii_PYR-1 RFIGRER----STGVTVLRYAIRTEIRLITSELAIDLARFPNLNTWSSED
MAB_1589|M.abscessus_ATCC_1997 RFVVTER----YTAPTEVRRAVNIEMRLLAGELAIDLARRDQMRLWDSAD
TH_0258|M.thermoresistible__bu IVQTILEG-----YRHEHRILAGEEDPATGADMFGELFTRAQQDGKLAAG
MLBr_02457|M.leprae_Br4923 QFVMANS-------SASKSKVIADSERIIARMLAVMIRRRMQEAGMDAGG
. . : : :
Mb0798|M.bovis_AF2122/97 IELVCTLICAVDGSVVSALVEGRDP--RAAALATVVDLIDVLAP--VDQR
Rv0775|M.tuberculosis_H37Rv IELVCTLICAVDGSVVSALVEGRDP--RAAALATVVDLIDVLAP--VDQR
MMAR_0334|M.marinum_M LNILATLFVNAMIVTAEAIEDAQSSEALEEIRRIAVKQLRMVAIGVAGWK
MUL_4787|M.ulcerans_Agy99 LNILATMFVNAMIVTAEAIEDAQSSEALEEIRRIAVKQLRMVAIGVAGWK
MAV_5169|M.avium_104 LNVLATLFVNAMIVIAEAIEDSQSAEAREDIRRLAVKQLRMIATGIAGWR
MSMEG_1741|M.smegmatis_MC2_155 LNILANLFVNSMISLAEALEDAADAESIEAIHRTAVKQMRMIAVGVNGWR
Mflv_4816|M.gilvum_PYR-GCK LNILASVFVNSMIAIAEQLEDVTDTASVDEIRRTAVKQLRMITVGVAGWR
Mvan_1626|M.vanbaalenii_PYR-1 LNILASVFVNSMIVIAESLEDATDPASIAEIRRIAIKQLRMITVGVAGWR
MAB_1589|M.abscessus_ATCC_1997 LTTAANLILS--IAANAVAELVQPDTDTTEVVDSASNALTMAFVGLQNWK
TH_0258|M.thermoresistible__bu IDVDHLSRVAQMLVSEGVRHWAAGGFGDRSFTEVVAGDIAALIDGYNLRL
MLBr_02457|M.leprae_Br4923 VEPWAYLIVGGVQLATHSWMSDPRMSADELIDYLTMLSWNALCGIVEVGG
: .
Mb0798|M.bovis_AF2122/97 PVPF----------------
Rv0775|M.tuberculosis_H37Rv PVPF----------------
MMAR_0334|M.marinum_M SRP-----------------
MUL_4787|M.ulcerans_Agy99 SRP-----------------
MAV_5169|M.avium_104 STP-----------------
MSMEG_1741|M.smegmatis_MC2_155 STD-----------------
Mflv_4816|M.gilvum_PYR-GCK SG------------------
Mvan_1626|M.vanbaalenii_PYR-1 SS------------------
MAB_1589|M.abscessus_ATCC_1997 PAQR----------------
TH_0258|M.thermoresistible__bu RR------------------
MLBr_02457|M.leprae_Br4923 SLEKFRKQPHPSPIIPPRGP