For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTTAEAPRRRSEKSRVAIVEATRALLLERGFDGLSIEAVAAKAGVGKQTIYRWWPSRHALVADVLLEDAD KILARMPKTDDVTADLASWAGTLAAALTTRRGHAMLKTLMAASLEHEDTAARLREGFSRPLIESVRDRLR DEDIDADHAQAAADALLGAVVNAVLSEGRSYSRQRAETSARIIVAGLRP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6564 | - | - | 100% (189) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5190 | - | 5e-16 | 32.09% (187) | TetR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_5567 | - | 2e-14 | 37.50% (120) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3192c | - | 3e-10 | 30.43% (161) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2374 | - | 3e-61 | 63.64% (187) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3167c | - | 4e-10 | 30.43% (161) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00717 | - | 7e-06 | 25.68% (222) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3462c | - | 1e-14 | 32.97% (182) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0340 | - | 3e-09 | 30.18% (169) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5267 | - | 4e-62 | 65.38% (182) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3283 | - | 2e-09 | 27.59% (174) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_2482 | - | 2e-09 | 30.87% (149) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4272 | - | 3e-64 | 64.52% (186) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2374|M.gilvum_PYR-GCK -----MTAE-------ISTPRRRSEKSRVAIVDATRGLLLERGFDKLTIE
Mvan_4272|M.vanbaalenii_PYR-1 -----MATD-------IAAPRRRSEKSRTAIVEATRKLLMERGFDKLTIE
MAV_5267|M.avium_104 -----MPTDP----NGPAAPRRRSEKSRTAIVTATRELLLERGFDGLTIE
MSMEG_6564|M.smegmatis_MC2_155 -----MTTA--------EAPRRRSEKSRVAIVEATRALLLERGFDGLSIE
Mb3192c|M.bovis_AF2122/97 -----MKADLPSLDKAPGAGRPRDPRIDSAILSATAELLVQIGYSNLSLA
Rv3167c|M.tuberculosis_H37Rv -----MKADLPSLDKAPGAGRPRDPRIDSAILSATAELLVQIGYSNLSLA
MUL_2482|M.ulcerans_Agy99 -----MKADPSSLDKAPGAGRPRDPRIDFAILSATMELLVQIGYSNLSLA
MMAR_0340|M.marinum_M -----MVAD---------FGRPRDPRIDGAVLRATVELLAETGYAGLLVS
TH_3283|M.thermoresistible__bu -----MPGS-----GARSPGRPRDPALDDAIRAAARDVVVEHGYDATTLA
MAB_3462c|M.abscessus_ATCC_199 MNETVGPGEVDTPRRHFGNRHGRSEAAREAVLHAADDLLVARGYAGVTME
MLBr_00717|M.leprae_Br4923 -----MTTAR---------RRLSPEDRRAELLALGAEVFGKRPYDEVRID
: : :. : :
Mflv_2374|M.gilvum_PYR-GCK AVAARAGVGKQTIYRWWPSRHALVADVILEDADRILRPI---DHTDDVAA
Mvan_4272|M.vanbaalenii_PYR-1 AVAARAGVGKQTIYRWWPSRHALVADVTLEDADRILRPV---ARTDDVAA
MAV_5267|M.avium_104 AVAARAGVGKQTIYRWWPTRPALVADVMLEDADRLLASV---EHSGDLAA
MSMEG_6564|M.smegmatis_MC2_155 AVAAKAGVGKQTIYRWWPSRHALVADVLLEDADKILARM---PKTDDVTA
Mb3192c|M.bovis_AF2122/97 AVAERAGTTKSALYRRWSSKAELVHEAAFPAAPTALQ-----AAAGDIAA
Rv3167c|M.tuberculosis_H37Rv AVAERAGTTKSALYRRWSSKAELVHEAAFPAAPTALQ-----AAAGDIAA
MUL_2482|M.ulcerans_Agy99 AVAERAGTTKSALYRRWSSKAELVHEAAFPVTPSALS-----APAGDFAG
MMAR_0340|M.marinum_M AIAKRAGTSKPAIYRRWPSKAHLVHEAVFPIDAATAV-----PDTGSPVD
TH_3283|M.thermoresistible__bu LIADRAGVSVPTIYRRWQHKHELIEEAVLHLDTFELP-----EPTGDLEA
MAB_3462c|M.abscessus_ATCC_199 GIAKAAGVAKQTVYRWWSSKVDVLMDVFLEDAACQLDP----PDLGGLEA
MLBr_00717|M.leprae_Br4923 EIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLYAATNIPPPAGLTMF
:* **. :*: : : .. . .
Mflv_2374|M.gilvum_PYR-GCK DVCAWATGLAKALTTARGNAMLRILTAAGMEHPDTAARLQAGFSVPLHDT
Mvan_4272|M.vanbaalenii_PYR-1 DLCAWAVTLATALTTVRGNAMLRALTTAGVEHQDTAARLHAGFNQPIHDA
MAV_5267|M.avium_104 DLVGWVGKLVTSLTTPRGSAMLRTLTVACMEHEDTAVKLRAGFSAPLHDS
MSMEG_6564|M.smegmatis_MC2_155 DLASWAGTLAAALTTRRGHAMLKTLMAASLEHEDTAARLREGFSRPLIES
Mb3192c|M.bovis_AF2122/97 DIRMMIAATRDVFTTPVVRAALPGLVADMTADAELNARVLARFADLFAA-
Rv3167c|M.tuberculosis_H37Rv DIRMMIAATRDVFTTPVVRAALPGLVADMTADAELNARVLARFADLFAA-
MUL_2482|M.ulcerans_Agy99 DIRMMVAATRDVFTTPVVRAALPGLVADMTAEADLNARVLSRFTELFAT-
MMAR_0340|M.marinum_M DLREMVRRTTAVLSTPAAKAALPGLIGEMAADPTLHSALLVRFGEIFGHG
TH_3283|M.thermoresistible__bu DLGTWVRLFLTVAMEPAARAAVPGLMSAYSRNPDDYRRLMTRGELPVRAA
MAB_3462c|M.abscessus_ATCC_199 DLRHHLSATAQFLAADDAGAVFRALIGQSQHDGQLADDFRGRYLREQQAR
MLBr_00717|M.leprae_Br4923 EEVRVGVLAYMAYHKQNPEAAWAAYVGLGRSDPVLLGIDDEAKNRQMEHI
: * .
Mflv_2374|M.gilvum_PYR-GCK VRNRLAASGFTDRAVQDG-----ADAIVG---GIVYAILNEGRAFES---
Mvan_4272|M.vanbaalenii_PYR-1 VRGRLTAEGLTAESARDA-----TDAIVG---GIVYAILSEGRSFDP---
MAV_5267|M.avium_104 VRARLLAEGVDAATAESA-----ADAIVG---GVVYPILSGAQRYSR---
MSMEG_6564|M.smegmatis_MC2_155 VRDRLRDEDIDADHAQAA-----ADALLG---AVVNAVLSEGRSYSR---
Mb3192c|M.bovis_AF2122/97 VRMRLREAVDRGEAHPDVDPDRLIELIGG---ATMLRMLLYPDDMLD---
Rv3167c|M.tuberculosis_H37Rv VRMRLREAVDRGEAHPDVDPDRLIELIGG---ATMLRMLLYPDDMLD---
MUL_2482|M.ulcerans_Agy99 VRIRLQEAVDRGEAHPDVDPNRMIELIGG---ATMLRVLLYPDQMLD---
MMAR_0340|M.marinum_M LTTWLDNAAARGQVRADVTAPELAEAIAG---IVLIGLLTRPGELEPGVG
TH_3283|M.thermoresistible__bu IAAMLERAKAAGQAAPDCDPDAVFELIRG---ATFLRALTHSDEDAE---
MAB_3462c|M.abscessus_ATCC_199 DQIPIARAVARGELPADVDVAHVAEQLVA---PLYYRVIVTGETVDA---
MLBr_00717|M.leprae_Br4923 MSRIGDVVSVVPESKLHPDIERDLRVIVHGWLAFTFEVCRQRIMDPSTDA
:
Mflv_2374|M.gilvum_PYR-GCK -RRAESISRAVLAGISAR-------------------
Mvan_4272|M.vanbaalenii_PYR-1 -HRAESITRTVIAGITTR-------------------
MAV_5267|M.avium_104 -RRAEHTTRLIVAALTAG-------------------
MSMEG_6564|M.smegmatis_MC2_155 -QRAETSARIIVAGLRP--------------------
Mb3192c|M.bovis_AF2122/97 DAWVDQTTAIVVRGVHRAAPGGSVV------------
Rv3167c|M.tuberculosis_H37Rv DAWVDQTTAIVVRGVHRAAPGGSVV------------
MUL_2482|M.ulcerans_Agy99 EAWVDQTTAILVHGVTR--------------------
MMAR_0340|M.marinum_M DAWIDRTTTLLLKGIRKGTPQ----------------
TH_3283|M.thermoresistible__bu -AFCTRITEAVLRAVRS--------------------
MAB_3462c|M.abscessus_ATCC_199 -AFVDRIVEDFLRRRE---------------------
MLBr_00717|M.leprae_Br4923 DRLADSCAHALLDAIARVPEISKELADAMAIARQPPQ
.: