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MTSTRTAEFVRRLTEPDPVVLAQVDNPDEITARILAATLEQAELVGMRRTTMEDVARRSGVGRATLYRRF PTKAALVDAVVLAEARRYLEGDAQAWAHGATFEDRMVNSTVFSVTFMREHALLKKLLRTEPETILPSLTV DAGVILDYATEYTIGLLRRELYGTETTPSQERHLRTVAELHTRLTLSFIVTPHTSINLATVDDTRSYVRN YLMPMVVGPR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2157 | - | - | 100% (220) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_5227 | - | 2e-14 | 31.03% (174) | TetR-family protein transcriptional regulator, putative |
| M. avium 104 | MAV_1333 | - | 1e-13 | 28.89% (180) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0068c | - | 8e-06 | 37.29% (59) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_5272 | - | 6e-14 | 29.00% (200) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0067c | - | 9e-06 | 37.29% (59) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00316 | - | 4e-06 | 46.00% (50) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1024 | - | 1e-23 | 34.03% (191) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0287 | - | 5e-13 | 26.42% (193) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_0962 | - | 5e-13 | 28.72% (188) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3720 | - | 1e-13 | 29.14% (175) | PUTATIVE transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4837 | - | 1e-13 | 26.94% (193) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0969 | - | 4e-13 | 29.02% (193) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2157|M.avium_104 MTSTRTAEFVRRLTEPDPVVLAQVDNPDEITARILAATLEQAELVGMRRT
MAB_1024|M.abscessus_ATCC_1997 ----------------------MSADPDPTGERILEAALQTMLSFGIRRA
Mflv_5272|M.gilvum_PYR-GCK --------------MRRARNTD---SPTEQESAILKAAAEEVALVGVGRL
Mvan_0969|M.vanbaalenii_PYR-1 --------------MRRTRTRN---TPTEQESAILKAAAEEVALVGVGRL
MMAR_0287|M.marinum_M ----------MQSRMGTETSTDGVESITDLDRTILDTARAVFETYGVRRA
MUL_4837|M.ulcerans_Agy99 --------------MGTETSTDGVESITDLDRTILDTAHAVFETYGVRRA
Mb0068c|M.bovis_AF2122/97 ---------------MAPTDRRVRADAARNRARVLEVAYQTFAADGLS-V
Rv0067c|M.tuberculosis_H37Rv ---------------MAPTDRRVRADAARNRARVLEVAYQTFAADGLS-V
MLBr_00316|M.leprae_Br4923 ----MSVPRSGLSVQMAQPARPLRADAARNRARILGVAYEAFATEGLS-V
MSMEG_0962|M.smegmatis_MC2_155 -----------------------MPGPDAASRAILDAALVEFERYGFRRV
TH_3720|M.thermoresistible__bu ---------------------VTEATALETREAIIMGAFACFRTYGLRKT
:: : *.
MAV_2157|M.avium_104 TMEDVARRSGVGRATLYRRFPTKAALVDAVVLAEARRYLEGDAQAWAHGA
MAB_1024|M.abscessus_ATCC_1997 TVDEIARRAGVSHMTVYRRWSNKTDLVLAVLMREAQAIFTSVDAEIAALD
Mflv_5272|M.gilvum_PYR-GCK SMDVVARQAGVSRSTLYRRFPSRDALITELGRQTFEFAMARLQTVAIDDG
Mvan_0969|M.vanbaalenii_PYR-1 SMDVVARQAGVSRSTLYRRFPTRDALITELGRQTFDFAMARLQTVAIDSG
MMAR_0287|M.marinum_M NIEDVATRAGVSRSTIYRRFPTKDELFERVVRREAELFFAALNQATNGHN
MUL_4837|M.ulcerans_Agy99 NIEDVATRAGVSRSTIYRRFPTKDELFERVVRREAELFFAALNQATNGHN
Mb0068c|M.bovis_AF2122/97 PVDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMHRIIDKGHALLKSKH
Rv0067c|M.tuberculosis_H37Rv PVDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMHRIIDKGHALLKSKH
MLBr_00316|M.leprae_Br4923 PIDEIARRAGVGAGTVYRHFPTKEALCAAVIGDRMPHLVDDGYVLLKSAG
MSMEG_0962|M.smegmatis_MC2_155 ALDDVARRAGVSRTTIYRRFANRDDLVGAVIERENVSLFADIAAELKDAK
TH_3720|M.thermoresistible__bu TIVDIARKAEVSRSTVYEYFPDKAAIVEACAEAASERFYRNMAKVVNRGE
: :* :: *. *:*. :. : :
MAV_2157|M.avium_104 TFEDRMVNSTVFSVTFMREHA--LLKKLLRTEPETILPSLTVDAGVILDY
MAB_1024|M.abscessus_ATCC_1997 SPEEKLVAGFTGIYWHVHTHP--LMRRAVETDPESVLPVMTSGAGPALDM
Mflv_5272|M.gilvum_PYR-GCK -PQQAAVAAFREGVRLLTGEP--VMRRFLQLDGE-FTATTEMVAEARLFL
Mvan_0969|M.vanbaalenii_PYR-1 -PQQAAVAAFTEGVRLLTGEP--VMRRFLQLDRE-FTATTEMVEEARLFL
MMAR_0287|M.marinum_M -PREAVIEAFTLGVRLIQDSP--LYSRIAESEPE-LFG---MFSRSHVFP
MUL_4837|M.ulcerans_Agy99 -PREAVIEAFTLGVRLIRDSP--LYSRIAESEPE-LFG---MFSRSHVFP
Mb0068c|M.bovis_AF2122/97 -PGDALFAFLRSMVLQWGATDRGLVEALAGVG-IEISSAAPEAEADFLDL
Rv0067c|M.tuberculosis_H37Rv -PGDALFAFLRSMVLQWGATDRGLVEALAGVG-IEISSAAPEAEADFLDL
MLBr_00316|M.leprae_Br4923 -PGEALFTYLRSLVLHWGATDRGLVDALAGAGGIDILGVAPDAEDAFLTI
MSMEG_0962|M.smegmatis_MC2_155 PQSNIYVEAFTLSILRFRRHR--VLNQMMKDEPALVLELAHRHYGAAIER
TH_3720|M.thermoresistible__bu DLEDKLVRACVFVTQARRVVQ-----GEKYFDEEEVSILLTRDSAVLLKE
: . . :
MAV_2157|M.avium_104 ATEYTIGLLRRELYGTETTPSQERHLRTVAELHTRLTLSFIVTPHTSINL
MAB_1024|M.abscessus_ATCC_1997 ATTYLAGHVSQSAGDLVDDPYG------IAEVFVRLTHSLILAPSPRREL
Mflv_5272|M.gilvum_PYR-GCK VS-AATAMAKALRAAGATMPDSE--LLAVAEVHIRLAASLVQVNTDVLDV
Mvan_0969|M.vanbaalenii_PYR-1 VS-AATAMAKALRAAGAGMPDDE--LLAVAEIHIRLAASLVQVSSDVLDV
MMAR_0287|M.marinum_M IGQFADGIAHTLRRCGADAPDAD--LANIADILLRVAVGIIMFPTERLDT
MUL_4837|M.ulcerans_Agy99 IGQFADGIAHTLRRCGADAPDAD--LANIADILLRVAVGIIMFPTERLDT
Mb0068c|M.bovis_AF2122/97 LT----DLLRAAQRAGTVRPDVD-----VLEVKTLLVGCQAMQSYNAELA
Rv0067c|M.tuberculosis_H37Rv LT----DLLRAAQRAGTVRPDVD-----VLEVKTLLVGCQAMQSYNAELA
MLBr_00316|M.leprae_Br4923 LS----DLLYAAQYAGTARTDVG-----VREVKSILVGCQAMEAYNSALA
MSMEG_0962|M.smegmatis_MC2_155 MAAALRVIFPEGFADRIGEAAVN----DLADTILRYALMALLIPS-VEPL
TH_3720|M.thermoresistible__bu CADFIAPYLSAGRVTGEVRKDLD--IPKASEWVARILFSLFNTPSPTIDM
:
MAV_2157|M.avium_104 ATVDDTRSYVRNYLMPMVVGPR----------
MAB_1024|M.abscessus_ATCC_1997 ATREDAQQYARRYILPIAQALVPAASPAVR--
Mflv_5272|M.gilvum_PYR-GCK TDDEAVARYARTYLAPLVR-------------
Mvan_0969|M.vanbaalenii_PYR-1 GDDEAVARYARTYLAPLVH-------------
MMAR_0287|M.marinum_M SDDAAVREYAARYLIPIITL------------
MUL_4837|M.ulcerans_Agy99 SDDAAVREYAARYLIPIITL------------
Mb0068c|M.bovis_AF2122/97 AKVTDVALDGLRANRK----------------
Rv0067c|M.tuberculosis_H37Rv AKVTDVALDGLRANRK----------------
MLBr_00316|M.leprae_Br4923 ERVTDVVVDGLRAAR-----------------
MSMEG_0962|M.smegmatis_MC2_155 ETADDIRSFATRHFLPSLPVSLRVVPA-----
TH_3720|M.thermoresistible__bu SDDGAVADFVRSFVLRGFVDDRPHRGRRSSAG