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VSADPDPTGERILEAALQTMLSFGIRRATVDEIARRAGVSHMTVYRRWSNKTDLVLAVLMREAQAIFTSV DAEIAALDSPEEKLVAGFTGIYWHVHTHPLMRRAVETDPESVLPVMTSGAGPALDMATTYLAGHVSQSAG DLVDDPYGIAEVFVRLTHSLILAPSPRRELATREDAQQYARRYILPIAQALVPAASPAVR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1024 | - | - | 100% (200) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2152 | - | 2e-20 | 32.80% (186) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1576 | - | 4e-17 | 27.81% (187) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2274c | - | 2e-10 | 42.86% (70) | transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0059 | - | 2e-20 | 31.82% (198) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2250c | - | 1e-09 | 47.46% (59) | transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 1e-06 | 31.71% (82) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_0287 | - | 3e-17 | 29.94% (177) | transcriptional regulatory protein |
| M. avium 104 | MAV_2157 | - | 1e-23 | 34.03% (191) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0962 | - | 2e-19 | 30.26% (195) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_2255 | - | 3e-18 | 28.93% (197) | TetR-family protein transcriptional regulator |
| M. ulcerans Agy99 | MUL_4837 | - | 3e-17 | 29.94% (177) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0855 | - | 6e-17 | 30.22% (182) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2274c|M.bovis_AF2122/97 -----------------------------MLSMSNDRADTGGRILRAAAS
Rv2250c|M.tuberculosis_H37Rv -----------------------------MLSMSNDRADTGGRILRAAAS
Mflv_0059|M.gilvum_PYR-GCK --------------------------------MS-GPDPASEQILDAAVV
Mvan_0855|M.vanbaalenii_PYR-1 --------------------------------MR-GTD-ATEHILDAAVV
MSMEG_0962|M.smegmatis_MC2_155 --------------------------------MP-GPDAASRAILDAALV
TH_2255|M.thermoresistible__bu --------------------------------MPERPDPARQAILDAAVV
MMAR_0287|M.marinum_M --------------------MQSRMGTETSTDGVESITDLDRTILDTARA
MUL_4837|M.ulcerans_Agy99 ------------------------MGTETSTDGVESITDLDRTILDTAHA
MAB_1024|M.abscessus_ATCC_1997 --------------------------------MSADPDPTGERILEAALQ
MAV_2157|M.avium_104 ----------MTSTRTAEFVRRLTEPDPVVLAQVDNPDEITARILAATLE
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
:* .:
Mb2274c|M.bovis_AF2122/97 CVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTS----HIA
Rv2250c|M.tuberculosis_H37Rv CVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTS----HIA
Mflv_0059|M.gilvum_PYR-GCK EFERHGFRRVALEDVARRAGVSRTTIYRRFANKDQLVGAVIERENVALFS
Mvan_0855|M.vanbaalenii_PYR-1 EFERHGFRRVALDDVARRAGVSRTTIYRRFANKDELVGAVIERENIQLFA
MSMEG_0962|M.smegmatis_MC2_155 EFERYGFRRVALDDVARRAGVSRTTIYRRFANRDDLVGAVIERENVSLFA
TH_2255|M.thermoresistible__bu EFEQHGFRKVALEDVARRAGVSRTTIYRRFTNRDELVAAVVDRENAALFA
MMAR_0287|M.marinum_M VFETYGVRRANIEDVATRAGVSRSTIYRRFPTKDELFERVVRREAELFFA
MUL_4837|M.ulcerans_Agy99 VFETYGVRRANIEDVATRAGVSRSTIYRRFPTKDELFERVVRREAELFFA
MAB_1024|M.abscessus_ATCC_1997 TMLSFGIRRATVDEIARRAGVSHMTVYRRWSNKTDLVLAVLMREAQAIFT
MAV_2157|M.avium_104 QAELVGMRRTTMEDVARRSGVGRATLYRRFPTKAALVDAVVLAEARRYLE
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
* . : ::* *:**.: .:*:::. : :: .
Mb2274c|M.bovis_AF2122/97 AVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERL
Rv2250c|M.tuberculosis_H37Rv DVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERL
Mflv_0059|M.gilvum_PYR-GCK DIATELKQAGPQSNYYVEAFTLSILKFRGHRVLHRMITEEPG--LVLELA
Mvan_0855|M.vanbaalenii_PYR-1 DIAAELKTAGPQSNYYVEAFTLSILKFRRHRVLHQMIIDEPG--LVLELA
MSMEG_0962|M.smegmatis_MC2_155 DIAAELKDAKPQSNIYVEAFTLSILRFRRHRVLNQMMKDEPA--LVLELA
TH_2255|M.thermoresistible__bu DIAAELKHSGPQGDYYVEAFTLAILKFRRHRVLHRMITDEPG--FILHLA
MMAR_0287|M.marinum_M ALNQATNGHNPR-EAVIEAFTLGVRLIQDSPLYSRIAESEP---ELFGMF
MUL_4837|M.ulcerans_Agy99 ALNQATNGHNPR-EAVIEAFTLGVRLIRDSPLYSRIAESEP---ELFGMF
MAB_1024|M.abscessus_ATCC_1997 SVDAEIAALDSPEEKLVAGFTGIYWHVHTHPLMRRAVETDPE--SVLPVM
MAV_2157|M.avium_104 GDAQAWAHGATFEDRMVNSTVFSVTFMREHALLKKLLRTEPE--TILPSL
MLBr_00815|M.leprae_Br4923 SVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDN--ITEPRV
: .. :
Mb2274c|M.bovis_AF2122/97 GTSQQVLIEGLAAR----LTVAQRSG---SVRSGDARRLATMVLLIAQST
Rv2250c|M.tuberculosis_H37Rv GTSQQVLIEGLAAR----LTVAQRSG---SVRSGDARRLATMVLLIAQST
Mflv_0059|M.gilvum_PYR-GCK SLYYRAAIERMAEA----LRVIFPPGFAERIGADAVDELADTILRYATMV
Mvan_0855|M.vanbaalenii_PYR-1 GRYHRAAIDRMAAA----LRVIFPPGFAERIGPAAVDELADCILRYAAMV
MSMEG_0962|M.smegmatis_MC2_155 HRHYGAAIERMAAA----LRVIFPEGFADRIGEAAVNDLADTILRYALMA
TH_2255|M.thermoresistible__bu QQHWGAAVERMAEA----LRVIFPAGFAERIGEAAVIEFADTILRYAAMA
MMAR_0287|M.marinum_M SRSHVFPIGQFADG----IAHTLRRCGADAP-DADLANIADILLRVAVGI
MUL_4837|M.ulcerans_Agy99 SRSHVFPIGQFADG----IAHTLRRCGADAP-DADLANIADILLRVAVGI
MAB_1024|M.abscessus_ATCC_1997 TSGAGPALDMATTY----LAGHVSQSAGDLVDDPYG--IAEVFVRLTHSL
MAV_2157|M.avium_104 TVDAGVILDYATEYTIGLLRRELYGTETTPSQERHLRTVAELHTRLTLSF
MLBr_00815|M.leprae_Br4923 AAQVRVATESCIDA----VFALISADSRLDPHRARMVAVGLVGISVDCAR
: ..
Mb2274c|M.bovis_AF2122/97 IQS--ADIVDSILDSAALATELTHALNGYLC----------
Rv2250c|M.tuberculosis_H37Rv IQS--ADIVDSILDSAALATELTHALNGYLC----------
Mflv_0059|M.gilvum_PYR-GCK LLLPSAQPLETADD--IRAFARHHFLPSLPEALRSVPA---
Mvan_0855|M.vanbaalenii_PYR-1 LLLPSAQPLETADD--VRAFARQHFLPSLPAALRTVPA---
MSMEG_0962|M.smegmatis_MC2_155 LLIPSVEPLETADD--IRSFATRHFLPSLPVSLRVVPA---
TH_2255|M.thermoresistible__bu LLLPSVQPLDTADD--IRAFATRHFLPSLPAALHTGSA---
MMAR_0287|M.marinum_M IMFPTER-LDTSDDAAVREYAARYLIPIITL----------
MUL_4837|M.ulcerans_Agy99 IMFPTER-LDTSDDAAVREYAARYLIPIITL----------
MAB_1024|M.abscessus_ATCC_1997 ILAPSPR-RELATREDAQQYARRYILPIAQALVPAASPAVR
MAV_2157|M.avium_104 IVTPHTS-INLATVDDTRSYVRNYLMPMVVGPR--------
MLBr_00815|M.leprae_Br4923 YWLDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL-------
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