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FPLRDRLAAELPFDSGLRDRNKMRTRLRLNSEAIRLFAERGYDDTSVQDIADAAEVSLRTLFRYFSGKDE ILFARDYDLSEFFDNLSRQPAAVPALHAIRTAYTQQRALTREETDVILQFRRAVAGNAALQGRFLDLQHR FRHQLARALAKRAGRRKPTEADEVAAATAQTLLDLAFSRWTDRGGRGSLAHLVDRMFATLDEIIGDTGES TVTA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0474 | - | - | 100% (215) | TetR-family protein transcriptional regulator |
| M. avium 104 | MAV_2657 | - | 3e-17 | 30.26% (195) | transcriptional regulator |
| M. avium 104 | MAV_4894 | - | 1e-15 | 36.24% (149) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0710c | - | 1e-10 | 29.17% (168) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_0350 | - | 1e-14 | 33.74% (163) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0691c | - | 1e-10 | 29.17% (168) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3837 | - | 2e-10 | 28.83% (163) | transcriptional regulatory protein TetR |
| M. marinum M | MMAR_1019 | - | 1e-10 | 32.52% (163) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_5673 | - | 2e-12 | 42.27% (97) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_1899 | - | 8e-11 | 32.00% (150) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_0771 | - | 9e-11 | 32.52% (163) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1156 | - | 4e-15 | 44.00% (100) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0710c|M.bovis_AF2122/97 ------------MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDD
Rv0691c|M.tuberculosis_H37Rv ------------MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDD
MMAR_1019|M.marinum_M ------------MAHESRAGRRPSTTKRHIADVAIDLFAARTFAEVSVDD
MUL_0771|M.ulcerans_Agy99 ------------MAHESRAGRRPSTTKRHIADVAIDLFAARTFAEVSVDD
TH_1899|M.thermoresistible__bu --------------------------------VALDLFADRGFDEVSVDD
MAB_3837|M.abscessus_ATCC_1997 -----------MNAQPARVGRRPSTTRDEITAVAMTLFAQHGFDEVSVDD
Mflv_0350|M.gilvum_PYR-GCK -------MEGMNPEQPGLRERKKTRTRETVRREAFRLFELNGYAQTTVDQ
Mvan_1156|M.vanbaalenii_PYR-1 -------MSGHDRPQS-LRERKKVRTRLAIRREAFRLFAKQGYANTTVEQ
MAV_0474|M.avium_104 MFPLRDRLAAELPFDSGLRDRNKMRTRLRLNSEAIRLFAERGYDDTSVQD
MSMEG_5673|M.smegmatis_MC2_155 --------MAYQTQQPGLRERKKQRTRATLISAAIDLCVRQGYEQTTVEQ
*: * . : :.:*::
Mb0710c|M.bovis_AF2122/97 IARAAGIARRTLFRYYASKNAIPWGDFSTHLAQLQGLLDNIDSRIQLRDA
Rv0691c|M.tuberculosis_H37Rv IARAAGIARRTLFRYYASKNAIPWGDFSTHLAQLQGLLDNIDSRIQLRDA
MMAR_1019|M.marinum_M VAQAAGIARRTLFRYYASKNAIPWGDFDTHLAQLQDLLERIDGHVRLGKA
MUL_0771|M.ulcerans_Agy99 VAQAAGIARRTLFRYYASKNAIPWGDFDTHLAQLQDLLERIDGHVRLGKA
TH_1899|M.thermoresistible__bu VAAAAGIGRRTLFRYYPSKNAIPWGDFDAHLDRMRDLLDGIGPDVPIGAA
MAB_3837|M.abscessus_ATCC_1997 IAAAAGIARRTVFRYYSSKNAIVWGDFDSHLGVMRALLDETADTVDTSTA
Mflv_0350|M.gilvum_PYR-GCK IAEAAFVSPRTFFRYFPTKESVLFSD-DLFNPIIEEFLAAPAELSPVAAY
Mvan_1156|M.vanbaalenii_PYR-1 IAEAADVSPRTFYRYFGVKERLLISD-DKISPIVEAFIAAPKELPIVPAY
MAV_0474|M.avium_104 IADAAEVSLRTLFRYFSGKDEILFAR-DYDLSEFFDNLSRQPAAVPALHA
MSMEG_5673|M.smegmatis_MC2_155 IAAAAEVSARTFSRYFATKDAVMLAFLDDVVDLVAGELAQQPPELGELDA
:* ** :. **. **: *: : . . . :
Mb0710c|M.bovis_AF2122/97 LRAALLAFNTFDESETIRHRKRMRVILQTPELQA--YSMTMYAGWR-EVI
Rv0691c|M.tuberculosis_H37Rv LRAALLAFNTFDESETIRHRKRMRVILQTPELQA--YSMTMYAGWR-EVI
MMAR_1019|M.marinum_M LREALLAFNTYDESETIRHRQRMRIILQTAELQA--YSMTMYAGWR-AVI
MUL_0771|M.ulcerans_Agy99 LREALLAFNTYDESETIRHRQRMRIILQTAELQA--YSMTMYAGWR-AVI
TH_1899|M.thermoresistible__bu LRSMLLAFNDFGEDETGRHRRRMRVILQTDALQA--HSMTMYAGWR-AVV
MAB_3837|M.abscessus_ATCC_1997 LRQAVLTFNDFPVDETPRHRMRMRMILEVPALQA--YSMLMYTGWR-DVI
Mflv_0350|M.gilvum_PYR-GCK RHAAARVFETMAGSDYDYIIARQRLLYDLPEAKG--ALWNEHVGAI-RRL
Mvan_1156|M.vanbaalenii_PYR-1 RHAVGTVFDGLTQEERDDFVAGEQMMYAIPEARG--LVYTEYVRLI-DLI
MAV_0474|M.avium_104 IRTAYTQQRALTREETDVILQFRRAVAGNAALQG--RFLDLQHRFR-HQL
MSMEG_5673|M.smegmatis_MC2_155 VFCAHITAFEKTRVAMPGQLTDDRLLAAARIFTSSPSLMQATMGFRPAPL
: : . :
Mb0710c|M.bovis_AF2122/97 AKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESV---SLTEAL
Rv0691c|M.tuberculosis_H37Rv AKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESV---SLTEAL
MMAR_1019|M.marinum_M AGFVARRLSVKPTDLVPQTVAWTMLGVALSAYEHWLSDESV---SLPEAL
MUL_0771|M.ulcerans_Agy99 AGFVARRLSVKPTDLVPQTVAWTMLGVALSAYEHWLSDESV---SLPEAL
TH_1899|M.thermoresistible__bu ADFVARRLGLAPSDLVPQTVAWTMLGVALSAYAYWLADESV---PLAQAL
MAB_3837|M.abscessus_ATCC_1997 AQFVARRSGTDPGSLLPQTVAWTLLGVALAAYEQWLADESS---KLTTLL
Mflv_0350|M.gilvum_PYR-GCK TSAIAKRLGRPEDDYQARVTAGAIIGVFMAA-----SDDEP---MSGEAF
Mvan_1156|M.vanbaalenii_PYR-1 ADALTDRPDGPTDEMERRVVAGAIVGVLIAA-----SHNNP---FPEDVL
MAV_0474|M.avium_104 ARALAKRAGRRKPTEADEVAAATAQTLLDLAFSRWTDRGGRG--SLAHLV
MSMEG_5673|M.smegmatis_MC2_155 FEVLAKRMGVSADDRKIALIASLWNAIMTTALVQLVPDVDWATVTVERIV
:: * . * : * .
Mb0710c|M.bovis_AF2122/97 GAAFDVVGAGLDRLNQ-----
Rv0691c|M.tuberculosis_H37Rv GAAFDVVGAGLDRLNQ-----
MMAR_1019|M.marinum_M GNAFDVVGAGLEKLD------
MUL_0771|M.ulcerans_Agy99 GNAFDVVGAGLEKLD------
TH_1899|M.thermoresistible__bu ADAFDAIRPGLDALDGKKFA-
MAB_3837|M.abscessus_ATCC_1997 GKGFDAAEVGLRALR------
Mflv_0350|M.gilvum_PYR-GCK LEALDLLDQALPR--------
Mvan_1156|M.vanbaalenii_PYR-1 LRSLEILGRRLT---------
MAV_0474|M.avium_104 DRMFATLDEIIGDTGESTVTA
MSMEG_5673|M.smegmatis_MC2_155 NQMRTTYAEFLEVAGRRHEFA
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