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MSAAVIPGYDRRMSRWQPNARERLEQAALELYTRQGFDQTTVDDIAQRAGLTERTFFRHFADKREVLFSG QAALIDLVTASVAAQEDTDPPLDVVAAALTAAGSALDGRGDRARQRQAVIDANPGLRERELIKLATLADT LAEALRQRGVEAPAARLAAEVGLAVFRVAFERWVQSPGGAPLPTLIAAAFADLRRIVA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1927 | - | - | 100% (198) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0989 | - | 6e-15 | 30.56% (180) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2270 | - | 2e-12 | 28.43% (197) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3860c | - | 8e-13 | 32.72% (162) | transcriptional regulatory protein TetR-family |
| M. gilvum PYR-GCK | Mflv_1676 | - | 1e-13 | 35.34% (133) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3830c | - | 8e-13 | 32.72% (162) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | MLBr_01733 | - | 3e-06 | 24.19% (186) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3837 | - | 2e-12 | 26.78% (183) | transcriptional regulatory protein TetR |
| M. marinum M | MMAR_2812 | - | 4e-16 | 30.86% (175) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0586 | - | 1e-35 | 42.78% (187) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3469 | - | 1e-48 | 53.93% (191) | TetR family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3524 | - | 3e-14 | 34.10% (173) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2933 | - | 9e-17 | 31.43% (175) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1927|M.vanbaalenii_PYR-1 ----------------------------------------MSAAVIPGYD
MSMEG_3469|M.smegmatis_MC2_155 --------------------------------------------------
MAV_0586|M.avium_104 --------------------------------------------------
Mb3860c|M.bovis_AF2122/97 ---------------------------------------------MVRPP
Rv3830c|M.tuberculosis_H37Rv ---------------------------------------------MVRPP
Mflv_1676|M.gilvum_PYR-GCK ---------------------------------------------MVRPA
MMAR_2812|M.marinum_M ---------------------------------------------MTVPT
MUL_2933|M.ulcerans_Agy99 ---------------------------------------------MTVPT
TH_3524|M.thermoresistible__bu --------------------------------------------------
MAB_3837|M.abscessus_ATCC_1997 ---------------------------------------------MNAQP
MLBr_01733|M.leprae_Br4923 MTRRSIHTRKPLKWSGCAGQHVRSGKVFDVGRISLSYPSMKPGVKIDARS
Mvan_1927|M.vanbaalenii_PYR-1 RRMSRWQPNARERLEQAALELYTRQGFDQTTVDDIAQRAGLTERTFFRHF
MSMEG_3469|M.smegmatis_MC2_155 --MSRWEPDARGRLERAALELYAERGFELTTVAEIAERAGLTERTFFRHY
MAV_0586|M.avium_104 --MARWEPDARARLVAAALDLFNERGYDQTTVAEIAERAGLTKSTFFRHF
Mb3860c|M.bovis_AF2122/97 --QTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHF
Rv3830c|M.tuberculosis_H37Rv --QTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHF
Mflv_1676|M.gilvum_PYR-GCK --QTVRSERTREALRQAAVVRFLAQGVEETTAEQIAADAGVSLRTFYRHF
MMAR_2812|M.marinum_M NRHELRRRSTHEALRRAALKSFACKGFAQVTVTELAREAGVTERTFFRHF
MUL_2933|M.ulcerans_Agy99 NRHELRRRSTHEALRRAALKSFARKGFAQVTVTELAREAGVTERTFFRHF
TH_3524|M.thermoresistible__bu ----VRGHRNREALIAAAIDLFTVNGYEQTTVEQIAEAAGVAPRTFFRHF
MAB_3837|M.abscessus_ATCC_1997 ARVGRRPSTTRDEITAVAMTLFAQHGFDEVSVDDIAAAAGIARRTVFRYY
MLBr_01733|M.leprae_Br4923 ERWREHRKKVRGEIVDAAFRALDRLG-PEVSVREIAEEAGTAKPKIYRHF
: : .*. * .:. ::* ** : ..:*::
Mvan_1927|M.vanbaalenii_PYR-1 ADKREVLFSGQAALIDLVTASVA-------AQEDTDPPLDVVAAALTAAG
MSMEG_3469|M.smegmatis_MC2_155 ADKREVLFGGQHVLQELFVGAVATAVGAPWASGPAVAALDAVAAGLDTVG
MAV_0586|M.avium_104 PDKRDVLAAGQDAIAQLLREGIA-------AAPADATPLALVCSGLKSAA
Mb3860c|M.bovis_AF2122/97 RSKHDLLFADYDAGLHWFRAALD-------ARPADESIIDSVQAAIFSFP
Rv3830c|M.tuberculosis_H37Rv RSKHDLLFADYDAGLHWFRAALD-------ARPADESIIDSVQAAIFSFP
Mflv_1676|M.gilvum_PYR-GCK ASKHDLLFADYDAGLHWFRAALA-------TRSPEDPILDTVQAAIMAAP
MMAR_2812|M.marinum_M PTKEAVLFQDYENQLEWLAQALA-------QRPVSEPLFDAVLASVAAFP
MUL_2933|M.ulcerans_Agy99 PTKEAVLFQDYENQLEWLARALA-------QRPVSEPLFDAVLASVAAFP
TH_3524|M.thermoresistible__bu AAKEDILFHGYADRLAEATRRFR--------AARSGSLWKALAEASEAVA
MAB_3837|M.abscessus_ATCC_1997 SSKNAIVWGDFDSHLGVMRALLD-------ETADTVDTSTALRQAVLTFN
MLBr_01733|M.leprae_Br4923 TDKSDLFEAIGIRLRDMLWAAIFP-----AIDLATDSAREIIRRSVDEYV
* :. . : .
Mvan_1927|M.vanbaalenii_PYR-1 SALDGR-GDRARQRQAVIDANPGLRERELIKLATLADTLAEALRQR----
MSMEG_3469|M.smegmatis_MC2_155 EMFAGR-HADARRRQAVVNANTALQERELIKLATLAAAIAEALRDR----
MAV_0586|M.avium_104 AAFTPFNKELAPRLRAAIAASAELQERNALKQIGLALAVSEALQAR----
Mb3860c|M.bovis_AF2122/97 YDVDAVTKIASLRRGELEPSRIVRHMR--EVEADFADAIQAQLRRRNCDI
Rv3830c|M.tuberculosis_H37Rv YDVDAVTKIASLRRGELEPSRIVRHMR--EVEADFADAIQAQLRRRNCDI
Mflv_1676|M.gilvum_PYR-GCK YDDWAVTKIAAMRSQELDAGRIVRHIR--QVEADFADAIDEHLARADGAS
MMAR_2812|M.marinum_M HDLEVVRQAATARSELISADRIANHLR--VVQSSFAQVLTAFVRDR---Y
MUL_2933|M.ulcerans_Agy99 HDLEVVRQAATARSELISADRIANHLR--VVQSSFAQVLTAFVRNR---Y
TH_3524|M.thermoresistible__bu TAIAENPGIFLVRAR-MYGELPALRATMLRINDDWIDQMTTEVARWLG--
MAB_3837|M.abscessus_ATCC_1997 -DFPVDETPRHRMRMRMILEVPALQAYSMLMYTGWRDVIAQFVARR----
MLBr_01733|M.leprae_Br4923 SLVDKHPNVLRVFIQGRFSAQSEATVRTLDEGREITLTMAEMFNNELR--
: .
Mvan_1927|M.vanbaalenii_PYR-1 ---GVEAPAARLAAEVGLAVFRVAFERWVQ--SPGGAPLP--TLIAAAFA
MSMEG_3469|M.smegmatis_MC2_155 ---GIPRATAEVAGEAGIAVFKVAFARWVE--VEHETDLR--MVMREVLD
MAV_0586|M.avium_104 ---GVPEPAAALAAELGALAFKTAYARWAE--PDESGDLG--DMACQALR
Mb3860c|M.bovis_AF2122/97 AGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSLGELA--RVCHVALE
Rv3830c|M.tuberculosis_H37Rv AGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSLGELA--RVCHVALE
Mflv_1676|M.gilvum_PYR-GCK PGT-DERMRTTVTARCIAAAVFGAMEVWMLGEDSSLPELD--RLCRHALD
MMAR_2812|M.marinum_M ADVANVDLVAEVAGATIAAALVVAVENWGR--NGCAVDLG--ELVAASLD
MUL_2933|M.ulcerans_Agy99 ADVANVDLVAEVAGATIAAALVVAVENWGR--YGCAEDLG--ELVAASLD
TH_3524|M.thermoresistible__bu -SDAAVDVRPRLAATVINGANRTAIDLWVS--ADGKGDLV--ELMADAVR
MAB_3837|M.abscessus_ATCC_1997 ---SGTDPGSLLPQTVAWTLLGVALAAYEQWLADESSKLT--TLLGKGFD
MLBr_01733|M.leprae_Br4923 -EMELNRAASELAAFAAFGSVASATEWWLGPEPDSPRRMPREQFVAHLTI
:. * : : .
Mvan_1927|M.vanbaalenii_PYR-1 DLRRIVA---------------------------
MSMEG_3469|M.smegmatis_MC2_155 DLRNLFVAG-------------------------
MAV_0586|M.avium_104 ELHAAAADLG------------------------
Mb3860c|M.bovis_AF2122/97 SLRVGISDTWTTLTVSS-----------------
Rv3830c|M.tuberculosis_H37Rv SLRVGISDTWTTLTVSS-----------------
Mflv_1676|M.gilvum_PYR-GCK LLRTGIADPA------------------------
MMAR_2812|M.marinum_M LVRSGLAPLS------------------------
MUL_2933|M.ulcerans_Agy99 LVRSGLAPLS------------------------
TH_3524|M.thermoresistible__bu LVRPTLDRIERESRTVANPVRRRDVV--------
MAB_3837|M.abscessus_ATCC_1997 AAEVGLRALR------------------------
MLBr_01733|M.leprae_Br4923 IMMAVIVGTAETLGISMNPDRPIHDAVPLDRSAS