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MGRVQDKVVLVTGAARGQGRSHAVKLAEEGADIILFDICHDIETNKYPLATPHDLEEAGLEVEKTGRRAY TAQVDVRDKEALTRELANAIAEFGGRLDVVVANAGICPLGGDLPITAFADAFDVDFVGVVNTVHAALPYL KSGASIITTGSIAGMIAATQAASAGVGPTGPGGMGYNLAKSFVDQYTKALALQLAPLSIRANAIHPTNVN TPMLQSEPMYRVFRPDLENPTAEDALLAFPAMQPMPIPFIEPQDVSNAVCFLASDESRYVTGLQFKVDAG AMLQF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1881 | - | - | 100% (285) | carveol dehydrogenase ((+)-trans-carveol dehydrogenase) |
| M. avium 104 | MAV_2598 | - | e-129 | 81.05% (285) | carveol dehydrogenase |
| M. avium 104 | MAV_2946 | - | 2e-90 | 59.15% (284) | carveol dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2771 | - | 3e-48 | 41.64% (281) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_2500 | - | 1e-84 | 56.84% (285) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2750 | - | 3e-48 | 41.64% (281) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01094 | - | 3e-16 | 29.03% (217) | short chain alcohol dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0072c | - | 1e-54 | 43.31% (284) | putative short chain dehydrogenase/reductase |
| M. marinum M | MMAR_4754 | - | 1e-58 | 44.83% (290) | short-chain type dehydrogenase/reductase |
| M. smegmatis MC2 155 | MSMEG_4801 | - | 2e-83 | 54.58% (284) | carveol dehydrogenase |
| M. thermoresistible (build 8) | TH_3929 | - | 1e-99 | 65.14% (284) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_3392 | fabG | 3e-45 | 37.89% (285) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_2006 | - | 1e-84 | 55.28% (284) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_1881|M.avium_104 ----MG----RVQDKVVLVTGAARGQGRSHAVKLAEEGADIILFDICHD-
TH_3929|M.thermoresistible__bu ----MN----RLTGKVVAITGAARGQGRSHAVHMADEGADIIALDICAD-
Mvan_2006|M.vanbaalenii_PYR-1 ----MG----KLDNKVAVVSGAARGQGRSHAVSLAAEGAHIIALDICAD-
Mflv_2500|M.gilvum_PYR-GCK ----MG----RVQGKVAFITGAARGQGRSHAVRLAEEGADIIAVDICRD-
MSMEG_4801|M.smegmatis_MC2_155 ----MGSAEGRVAGKVAFITGAARGQGRSHAVRLAEEGADIIAVDLCQD-
MAB_0072c|M.abscessus_ATCC_199 ----MTG---RLTGKVALVTGAARGIGRAQAVRFAQEGADIIALDICAP-
MMAR_4754|M.marinum_M MTEQLGG---RVAGKVAFITGAARGQGRSHAVRLAQEGADIIAVDVCKPI
Mb2771|M.bovis_AF2122/97 ---MIDR---PLEGKVAFITGAARGLGRAHAVRLAADGANIIAVDICEQ-
Rv2750|M.tuberculosis_H37Rv ---MIDR---PLEGKVAFITGAARGLGRAHAVRLAADGANIIAVDICEQ-
MUL_3392|M.ulcerans_Agy99 MSRPLDG---PLSGRVAFITGAARGQGRAHALRLARDGADVIAVDLCDQ-
MLBr_01094|M.leprae_Br4923 MEG--------FAGKVAVVTGAGSGIGQALAIELARSGAKLAISDVDGE-
. .:*. ::**. * *:: *: :* .**.: *:
MAV_1881|M.avium_104 IETNKYPLATPHDLEEAGLEVEKTGRRAYTAQVDVRDKEALTRELANAIA
TH_3929|M.thermoresistible__bu IATNEYPLATREDLEETARLVEKAGRRAITAEVDVRDRARLKQVLDDAVA
Mvan_2006|M.vanbaalenii_PYR-1 LEGNTYPLSRPEDLDETARLAEKEGVRVHTAIVDVRERAAVWKAVADGVD
Mflv_2500|M.gilvum_PYR-GCK YDTVGYRMATPEDLEETKNFVEKTGQRIVTAQADVRNEAELRAALEAGLA
MSMEG_4801|M.smegmatis_MC2_155 IDSIGYSLATPEDLEETARYVEKAGRRIVTAQADVRDAAQLKEALERGVS
MAB_0072c|M.abscessus_ATCC_199 VHTTITPPATRADLDKTSELVESAGRRVIPGVVDVRNLRDVQTFTQDAVT
MMAR_4754|M.marinum_M VENTTIPASTPEDLAETADLVKGHNRRIFTAEADVRDYDALKAAVDAGVD
Mb2771|M.bovis_AF2122/97 IASVPYPLSTADDLAATVELVEDAGGGIVARQGDVRDRASLSVALQAGLD
Rv2750|M.tuberculosis_H37Rv IASVPYPLSTADDLAATVELVEDAGGGIVARQGDVRDRASLSVALQAGLD
MUL_3392|M.ulcerans_Agy99 IASVPYPLGTAEELATTVKLVEDTGARIVASQADVRDREALAAALQAGID
MLBr_01094|M.leprae_Br4923 ------------GLAQTEGQLKAIGASARTDRLDVTEREAFLTYADVVHE
* : : . . ** : .
MAV_1881|M.avium_104 EFGGRLDVVVANAGICP---LGGDLPITAFADAFDVDFVGVVNTVHAALP
TH_3929|M.thermoresistible__bu ELGG-LHVVVANAGICP---QGNHLPYKAYIDAFDVDFVGVVNTIHVGLD
Mvan_2006|M.vanbaalenii_PYR-1 ALGR-LDIVVANAGICP---MGRGQTIQSWSDAIDTDLVGVFNVIQASLP
Mflv_2500|M.gilvum_PYR-GCK EFGK-VDIVVAQAGIAA---MKGQPAMQAWTDGINTNFVGTINAIQVALP
MSMEG_4801|M.smegmatis_MC2_155 ELGK-LDIVVAQAGIAA---MKGNPPLQAWTDGINTNLVGTINAIQVALP
MAB_0072c|M.abscessus_ATCC_199 EFGG-LDIVCATAGITSRRMLLDMP-ESDWQTMLDVNLTGVWHTTRAATP
MMAR_4754|M.marinum_M ELGR-LDIIVANAGIGNGGATLDKTSEHDWQEMIDVNLSGVWKSVKAAVP
Mb2771|M.bovis_AF2122/97 EFGR-LDIVVANAGIA-----MMQAGDDGWRDVIDVNLTGVFHTVQVAIP
Rv2750|M.tuberculosis_H37Rv EFGR-LDIVVANAGIA-----MMQAGDDGWRDVIDVNLTGVFHTVQVAIP
MUL_3392|M.ulcerans_Agy99 ELGQ-VDIVVANAGIA-----PMQSGDDGWRDVIDVNLSGAYYTVEVAIP
MLBr_01094|M.leprae_Br4923 NFGK-VNQIYNNAGIAFTG-DVEVSHFKDIERVMDVDYWGVVNGTKAFLP
:* :. : *** ::.: *. ..
MAV_1881|M.avium_104 YLKS---GASIITTGSIAGMIAATQAASAGVGPTGPGGMGYNLAKSFVDQ
TH_3929|M.thermoresistible__bu YLGE---GGSVIVTGSIAGLVDQKDMANGG-GPSGPGGAGYGMAKKMVRD
Mvan_2006|M.vanbaalenii_PYR-1 HVND---GASIIATGSLAAQLG--SATNQG-----PGGSAYSLAKQVVAH
Mflv_2500|M.gilvum_PYR-GCK HLKE---GASIIATASAAALMDAHNKPNPG---GDPGGMGYMISKRLISE
MSMEG_4801|M.smegmatis_MC2_155 HLSE---GASIVATASAAALMDAHNKPNPG---ADPGGMGYMVSKRMISE
MAB_0072c|M.abscessus_ATCC_199 HLIARG-GGAMVLVSSIAGLRGLVGVS------------HYVAAKHGVVG
MMAR_4754|M.marinum_M HLIAGGNGGSIVLTSSVGGMKAYPHCG------------NYVAAKHGVVG
Mb2771|M.bovis_AF2122/97 TLIEQGTGGSIVLISSAAGLVGIGSSDPGS--------LGYAAAKHGVVG
Rv2750|M.tuberculosis_H37Rv TLIEQGTGGSIVLISSAAGLVGIGSSDPGS--------LGYAAAKHGVVG
MUL_3392|M.ulcerans_Agy99 TMIEQGRGGSIVLISSAAGLVGISSADAGA--------IGYVASKHALVG
MLBr_01094|M.leprae_Br4923 YLISSG-DGHVINISSVFGLFSVPGQA------------AYNSAKFAVRG
: .. :: .* . * :* :
MAV_1881|M.avium_104 YTKAL--ALQLAPLSIRANAIHPTNVNTPMLQSEPMYRVFRPDLENPTAE
TH_3929|M.thermoresistible__bu YTKAL--ALTLAPHKIRINAVHPTNVNTDMLHNMSMYRVFRPDLTEPTRE
Mvan_2006|M.vanbaalenii_PYR-1 YVNDL--SIQLAKRMIRVNAIHPTNVNTDMLHNEGLYRVFRPDLKEPTRE
Mflv_2500|M.gilvum_PYR-GCK YVHAL--ATELAVRGIRANVIHPTNCNTDMLQSEPMYRSFRPDLENPTRA
MSMEG_4801|M.smegmatis_MC2_155 YVHYL--ATELTPLGIRANVIHPTNCNTDMLQSEPMYRSFRPDLEHPTRA
MAB_0072c|M.abscessus_ATCC_199 LMRSL--AIELAPHKIRVNTVHPTNVDTPMIQNEFVRTLFRPDLEQPTRE
MMAR_4754|M.marinum_M LMRSF--AVELGQHMIRVNSVHPTHVRTPMLHNEGTFKMFRPDLENPGPD
Mb2771|M.bovis_AF2122/97 LMRAY--ANHLAPQNIRVNSVHPCGVDTPMINNEFFQQWLT-------TA
Rv2750|M.tuberculosis_H37Rv LMRAY--ANHLAPQNIRVNSVHPCGVDTPMINNEFFQQWLT-------TA
MUL_3392|M.ulcerans_Agy99 LMRVY--ANLLAPHSIRVNSLHPSGVDPPMINNEFIRHWLAD-----LVA
MLBr_01094|M.leprae_Br4923 FTEALREEMALAGRPVNVTTVYPGGIKTAIARNATAAEGLDVS-KIASRF
. * :. . ::* . : .. :
MAV_1881|M.avium_104 DALLAFPAMQPMPIPFIEPQDVSNAVCFLASDESRYVTGLQFKVDAGAML
TH_3929|M.thermoresistible__bu DAEVVFPLLQAMPIPYVEPDDVSHAVVYLASDESRYVTGQQLFVDAGAGL
Mvan_2006|M.vanbaalenii_PYR-1 EAEEAFPAMQAMPIPYIEPRDVSNAVVFLAGDDSRYITGTQLRIDAGGYV
Mflv_2500|M.gilvum_PYR-GCK DAEPVFGVQQAMKVNFIEPEDISNAVLWLASDESRYVTGMQLRVDAGGYL
MSMEG_4801|M.smegmatis_MC2_155 DAEPVFYVQQAMKVPWVEPSDISNAVLWLASDESRFVTGMQLRVDAGGYL
MAB_0072c|M.abscessus_ATCC_199 DFAAAAKTMNLLDLPWVEPLDIANASLFLASDEARYITSVSLPVDAGSTQ
MMAR_4754|M.marinum_M DMAPICQLFHTLPIPWVEAEDISNAVLFLASDESRYITGVTLPVDAGGCL
Mb2771|M.bovis_AF2122/97 DMDAPHNLGNALPVELVQPTDIANAVAWLASEEARYVTGVTLPVDAGFVN
Rv2750|M.tuberculosis_H37Rv DMDAPHNLGNALPVELVQPTDIANAVAWLASEEARYVTGVTLPVDAGFVN
MUL_3392|M.ulcerans_Agy99 ETGSGPGAGNALPVQILQADDIAGALAWLVSDEARYITGVALPVDAGCVN
MLBr_01094|M.leprae_Br4923 DTWVAHTSPQHAARIILKAVRKKKARVLVGPDAKVANVVVRFSGGAGYQR
: : ::. * : : . : .**
MAV_1881|M.avium_104 QF------------
TH_3929|M.thermoresistible__bu KMGV----------
Mvan_2006|M.vanbaalenii_PYR-1 KAVPWKG-------
Mflv_2500|M.gilvum_PYR-GCK KWYDYHV-------
MSMEG_4801|M.smegmatis_MC2_155 KWYDYHV-------
MAB_0072c|M.abscessus_ATCC_199 R-------------
MMAR_4754|M.marinum_M K-------------
Mb2771|M.bovis_AF2122/97 KR------------
Rv2750|M.tuberculosis_H37Rv KR------------
MUL_3392|M.ulcerans_Agy99 KR------------
MLBr_01094|M.leprae_Br4923 LFAQVASRLILNQR