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MGSAEGRVAGKVAFITGAARGQGRSHAVRLAEEGADIIAVDLCQDIDSIGYSLATPEDLEETARYVEKAG RRIVTAQADVRDAAQLKEALERGVSELGKLDIVVAQAGIAAMKGNPPLQAWTDGINTNLVGTINAIQVAL PHLSEGASIVATASAAALMDAHNKPNPGADPGGMGYMVSKRMISEYVHYLATELTPLGIRANVIHPTNCN TDMLQSEPMYRSFRPDLEHPTRADAEPVFYVQQAMKVPWVEPSDISNAVLWLASDESRFVTGMQLRVDAG GYLKWYDYHV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4801 | - | - | 100% (290) | carveol dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_4849 | - | 1e-62 | 46.21% (290) | carveol dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_6031 | - | 1e-61 | 48.61% (288) | carveol dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2771 | - | 1e-58 | 46.72% (274) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_2500 | - | 1e-141 | 84.91% (285) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2750 | - | 1e-58 | 46.72% (274) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_00862 | ephD | 7e-09 | 26.24% (221) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0072c | - | 2e-53 | 42.29% (279) | putative short chain dehydrogenase/reductase |
| M. marinum M | MMAR_4754 | - | 2e-65 | 49.65% (286) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_2946 | - | 6e-87 | 58.51% (282) | carveol dehydrogenase |
| M. thermoresistible (build 8) | TH_4131 | - | 1e-137 | 82.81% (285) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_3392 | fabG | 2e-55 | 44.09% (279) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_4158 | - | 1e-137 | 82.39% (284) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2771|M.bovis_AF2122/97 --------------------------------------------------
Rv2750|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3392|M.ulcerans_Agy99 --------------------------------------------------
MAB_0072c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_4754|M.marinum_M --------------------------------------------------
Mflv_2500|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4158|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4801|M.smegmatis_MC2_155 --------------------------------------------------
TH_4131|M.thermoresistible__bu --------------------------------------------------
MAV_2946|M.avium_104 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 MPATQSIHKVPHQFVESPDGVRLAIYQSGQPEGPAIVLVHGFPDSHVLWD
Mb2771|M.bovis_AF2122/97 --------------------------------------------------
Rv2750|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3392|M.ulcerans_Agy99 --------------------------------------------------
MAB_0072c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_4754|M.marinum_M --------------------------------------------------
Mflv_2500|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4158|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4801|M.smegmatis_MC2_155 --------------------------------------------------
TH_4131|M.thermoresistible__bu --------------------------------------------------
MAV_2946|M.avium_104 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 GVVPLLAKRFRIVRYDNRGVGQSSVPKPVSAYTMTRFADDFAAVIDELSP
Mb2771|M.bovis_AF2122/97 --------------------------------------------------
Rv2750|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3392|M.ulcerans_Agy99 --------------------------------------------------
MAB_0072c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_4754|M.marinum_M --------------------------------------------------
Mflv_2500|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4158|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4801|M.smegmatis_MC2_155 --------------------------------------------------
TH_4131|M.thermoresistible__bu --------------------------------------------------
MAV_2946|M.avium_104 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 DRPVHVLAHDWGSVGVWEYLSRSGASDRVASFTSVSGPSQDQLVDYILSG
Mb2771|M.bovis_AF2122/97 --------------------------------------------------
Rv2750|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3392|M.ulcerans_Agy99 --------------------------------------------------
MAB_0072c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_4754|M.marinum_M --------------------------------------------------
Mflv_2500|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4158|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4801|M.smegmatis_MC2_155 --------------------------------------------------
TH_4131|M.thermoresistible__bu --------------------------------------------------
MAV_2946|M.avium_104 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 LRRPWRPRTFARAVSQLFRLTYMVLFSIPVLVPMVLWIALSSATIRRTMV
Mb2771|M.bovis_AF2122/97 --------------------------------------------------
Rv2750|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3392|M.ulcerans_Agy99 --------------------------------------------------
MAB_0072c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_4754|M.marinum_M --------------------------------------------------
Mflv_2500|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4158|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4801|M.smegmatis_MC2_155 --------------------------------------------------
TH_4131|M.thermoresistible__bu --------------------------------------------------
MAV_2946|M.avium_104 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 DNISTDQIHHSATLARDAAHSVKTYPANYFRAFSGRRRGKGVPVVNVPVQ
Mb2771|M.bovis_AF2122/97 --------------------------------------------------
Rv2750|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3392|M.ulcerans_Agy99 --------------------------------------------------
MAB_0072c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_4754|M.marinum_M --------------------------------------------------
Mflv_2500|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4158|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4801|M.smegmatis_MC2_155 --------------------------------------------------
TH_4131|M.thermoresistible__bu --------------------------------------------------
MAV_2946|M.avium_104 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 LIVNTMDRYVRPYGYDATARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHD
Mb2771|M.bovis_AF2122/97 -----------------MIDR---PLEGKVAFITGAARGLGRAHAVRLAA
Rv2750|M.tuberculosis_H37Rv -----------------MIDR---PLEGKVAFITGAARGLGRAHAVRLAA
MUL_3392|M.ulcerans_Agy99 --------------MSRPLDG---PLSGRVAFITGAARGQGRAHALRLAR
MAB_0072c|M.abscessus_ATCC_199 ------------------MTG---RLTGKVALVTGAARGIGRAQAVRFAQ
MMAR_4754|M.marinum_M --------------MTEQLGG---RVAGKVAFITGAARGQGRSHAVRLAQ
Mflv_2500|M.gilvum_PYR-GCK ------------------MG----RVQGKVAFITGAARGQGRSHAVRLAE
Mvan_4158|M.vanbaalenii_PYR-1 ------------------MG----RVQGKVAFITGAARGQGRSHAVRLAE
MSMEG_4801|M.smegmatis_MC2_155 ------------------MGSAEGRVAGKVAFITGAARGQGRSHAVRLAE
TH_4131|M.thermoresistible__bu ------------------VG----RVEGKVAFITGAARGQGRSHAVRLAE
MAV_2946|M.avium_104 ------------------MG----RVTGKVAVISGAARGQGRSHARMLAA
MLBr_00862|M.leprae_Br4923 LADLVDGKQPSRALLRAQVGRSRDTFGDTLVSVTGAGSGIGRETALALAR
: . . :. ::**. * ** * :*
Mb2771|M.bovis_AF2122/97 DGANIIAVDICEQ-IASVPYPLSTADDLAATVELVEDAGGGIVARQGDVR
Rv2750|M.tuberculosis_H37Rv DGANIIAVDICEQ-IASVPYPLSTADDLAATVELVEDAGGGIVARQGDVR
MUL_3392|M.ulcerans_Agy99 DGADVIAVDLCDQ-IASVPYPLGTAEELATTVKLVEDTGARIVASQADVR
MAB_0072c|M.abscessus_ATCC_199 EGADIIALDICAP-VHTTITPPATRADLDKTSELVESAGRRVIPGVVDVR
MMAR_4754|M.marinum_M EGADIIAVDVCKPIVENTTIPASTPEDLAETADLVKGHNRRIFTAEADVR
Mflv_2500|M.gilvum_PYR-GCK EGADIIAVDICRD-YDTVGYRMATPEDLEETKNFVEKTGQRIVTAQADVR
Mvan_4158|M.vanbaalenii_PYR-1 EGADIIAVDLCEN-VDTIGYPMATAEDLEETAAFVEKTGQRIVTAKADVR
MSMEG_4801|M.smegmatis_MC2_155 EGADIIAVDLCQD-IDSIGYSLATPEDLEETARYVEKAGRRIVTAQADVR
TH_4131|M.thermoresistible__bu EGADIIAVDICAD-IETIGYSMAKPEDLEETAKLVEKTGRGVYTAQADVR
MAV_2946|M.avium_104 EGADIIAVDLCAD-IETNEYPLARPEDLDETARLVEKEGQRAITAVADVR
MLBr_00862|M.leprae_Br4923 RGAEVVVSDIDEA-------------AAKNTAAQIVASGGVAYAYALDVS
**:::. *: * : . . **
Mb2771|M.bovis_AF2122/97 DRASLSVALQAGLDEFGRLDIVVANAGIA-----MMQAGDDGWRDVIDVN
Rv2750|M.tuberculosis_H37Rv DRASLSVALQAGLDEFGRLDIVVANAGIA-----MMQAGDDGWRDVIDVN
MUL_3392|M.ulcerans_Agy99 DREALAAALQAGIDELGQVDIVVANAGIA-----PMQSGDDGWRDVIDVN
MAB_0072c|M.abscessus_ATCC_199 NLRDVQTFTQDAVTEFGGLDIVCATAGITSRRMLLDMP-ESDWQTMLDVN
MMAR_4754|M.marinum_M DYDALKAAVDAGVDELGRLDIIVANAGIGNGGATLDKTSEHDWQEMIDVN
Mflv_2500|M.gilvum_PYR-GCK NEAELRAALEAGLAEFGKVDIVVAQAGIAA---MKGQPAMQAWTDGINTN
Mvan_4158|M.vanbaalenii_PYR-1 DAAQLKKALEDGIAQLGGVDIVVAQAGIAG---MKGNPPMQAWTDVINTN
MSMEG_4801|M.smegmatis_MC2_155 DAAQLKEALERGVSELGKLDIVVAQAGIAA---MKGNPPLQAWTDGINTN
TH_4131|M.thermoresistible__bu NADQLRTALEGGLKEFGKVDIVVAQAGVAG---MKGQPPLQAWTDVMNTN
MAV_2946|M.avium_104 DRVVLSAAIDAGVAEFGHLDIVVANAGICP---LTAGLPPQAFADAVDVD
MLBr_00862|M.leprae_Br4923 DAAAVEAFAEQVSAKHGVPDIVVNNAGIGQAG-RFLDTPPEEFDRVLAVN
: : : : * **: **: : : .:
Mb2771|M.bovis_AF2122/97 LTGVFHTVQVAIPTLIEQGTGGSIVLISSAAGLVGIGSSDPGSL------
Rv2750|M.tuberculosis_H37Rv LTGVFHTVQVAIPTLIEQGTGGSIVLISSAAGLVGIGSSDPGSL------
MUL_3392|M.ulcerans_Agy99 LSGAYYTVEVAIPTMIEQGRGGSIVLISSAAGLVGISSADAGAI------
MAB_0072c|M.abscessus_ATCC_199 LTGVWHTTRAATPHLIARG-GGAMVLVSSIAGLRGLVGVS----------
MMAR_4754|M.marinum_M LSGVWKSVKAAVPHLIAGGNGGSIVLTSSVGGMKAYPHCG----------
Mflv_2500|M.gilvum_PYR-GCK FVGTINAIQVALPHLKEGA---SIIATASAAALMDAHNKPNPGG---DPG
Mvan_4158|M.vanbaalenii_PYR-1 LVGTINAIQVALPHLKEGA---AIVATGSTAALMDAHNKPNPGN---DPG
MSMEG_4801|M.smegmatis_MC2_155 LVGTINAIQVALPHLSEGA---SIVATASAAALMDAHNKPNPGA---DPG
TH_4131|M.thermoresistible__bu LVGTMNAIQVALPHLKEGA---SIIATASAAALMDAHQKPNPGA---DPG
MAV_2946|M.avium_104 LGGVLNLVHASLKHLRAGA---SIIVIGSNAAFMSSLNTSGAGSGIGGPG
MLBr_00862|M.leprae_Br4923 LGGVVNCCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLS----------
: *. .. : . :: .* ..
Mb2771|M.bovis_AF2122/97 --GYAAAKHGVVGLMRAYANHLAPQNIRVNSVHPCGVDTPMINNEFFQQ-
Rv2750|M.tuberculosis_H37Rv --GYAAAKHGVVGLMRAYANHLAPQNIRVNSVHPCGVDTPMINNEFFQQ-
MUL_3392|M.ulcerans_Agy99 --GYVASKHALVGLMRVYANLLAPHSIRVNSLHPSGVDPPMINNEFIRH-
MAB_0072c|M.abscessus_ATCC_199 --HYVAAKHGVVGLMRSLAIELAPHKIRVNTVHPTNVDTPMIQNEFVRT-
MMAR_4754|M.marinum_M --NYVAAKHGVVGLMRSFAVELGQHMIRVNSVHPTHVRTPMLHNEGTFK-
Mflv_2500|M.gilvum_PYR-GCK GMGYMISKRLISEYVHALATELAVRGIRANVIHPTNCNTDMLQSEPMYR-
Mvan_4158|M.vanbaalenii_PYR-1 GMAYMTSKRLLSQYVHDLATELAVRGIRANVVHPTNCNTDMLQSPPMYK-
MSMEG_4801|M.smegmatis_MC2_155 GMGYMVSKRMISEYVHYLATELTPLGIRANVIHPTNCNTDMLQSEPMYR-
TH_4131|M.thermoresistible__bu GMAYMSSKRLLAQYVHDLATELAVRGIRANVIHPTNCNTDMLQSEPMYR-
MAV_2946|M.avium_104 GAGYAFAKLAAAHYVNDFALALAPFSIRMNAVHPTNVNTDMLHSPPMYR-
MLBr_00862|M.leprae_Br4923 --AYCTSKAATYMFSDCLRAELDAVGVGLTTICPGVIDTNIIQSTRIDTP
* :* * : . : * . :::.
Mb2771|M.bovis_AF2122/97 WLT-------TADMDAPHNLGNALP---VELVQPTDIANAVAWLASEEAR
Rv2750|M.tuberculosis_H37Rv WLT-------TADMDAPHNLGNALP---VELVQPTDIANAVAWLASEEAR
MUL_3392|M.ulcerans_Agy99 WLAD-----LVAETGSGPGAGNALP---VQILQADDIAGALAWLVSDEAR
MAB_0072c|M.abscessus_ATCC_199 LFRPDLEQPTREDFAAAAKTMNLLD---LPWVEPLDIANASLFLASDEAR
MMAR_4754|M.marinum_M MFRPDLENPGPDDMAPICQLFHTLP---IPWVEAEDISNAVLFLASDESR
Mflv_2500|M.gilvum_PYR-GCK SFRPDLENPTRADAEPVFGVQQAMK---VNFIEPEDISNAVLWLASDESR
Mvan_4158|M.vanbaalenii_PYR-1 SFRPDLENPTRADAEPVFGVQQAMK---VNFIEPEDISNAILWLVSDEAR
MSMEG_4801|M.smegmatis_MC2_155 SFRPDLEHPTRADAEPVFYVQQAMK---VPWVEPSDISNAVLWLASDESR
TH_4131|M.thermoresistible__bu SFRPDLENPTRADAEPVFGVQQAMR---VPYVEPEDISNAVLWLASEEAR
MAV_2946|M.avium_104 AFRPDLPAPTREDAEPVFPLVQAMP---VPYVEPEDISEAVLFLASDAAR
MLBr_00862|M.leprae_Br4923 TAKQERVRDRRGQLDMMFRLRRYGPDKVADTILSAIKKNKPIRPVAPEAY
: . : . .: :
Mb2771|M.bovis_AF2122/97 YVTGVTLPVDAGFVNKR------
Rv2750|M.tuberculosis_H37Rv YVTGVTLPVDAGFVNKR------
MUL_3392|M.ulcerans_Agy99 YITGVALPVDAGCVNKR------
MAB_0072c|M.abscessus_ATCC_199 YITSVSLPVDAGSTQR-------
MMAR_4754|M.marinum_M YITGVTLPVDAGGCLK-------
Mflv_2500|M.gilvum_PYR-GCK YVTGMQLRVDAGGYLKWYDYHV-
Mvan_4158|M.vanbaalenii_PYR-1 YVTGMQLRVDAGGYLKWYDYHA-
MSMEG_4801|M.smegmatis_MC2_155 FVTGMQLRVDAGGYLKWYDYHV-
TH_4131|M.thermoresistible__bu YVTGMQLRVDAGGYLKWYDYHV-
MAV_2946|M.avium_104 YITGQQLRVDAGGFLKVKPWSGG
MLBr_00862|M.leprae_Br4923 ALYGISRVLPQVLRSTARIRVI-
: . :