For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3929 | - | - | 100% (286) | short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_4131 | - | 2e-78 | 53.19% (282) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_3237 | - | 7e-64 | 47.55% (286) | PUTATIVE short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2771 | - | 1e-52 | 44.96% (278) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_4148 | - | 4e-82 | 54.55% (286) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2750 | - | 1e-52 | 44.96% (278) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01094 | - | 2e-14 | 29.77% (215) | short chain alcohol dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0072c | - | 4e-58 | 45.55% (281) | putative short chain dehydrogenase/reductase |
| M. marinum M | MMAR_4754 | - | 1e-60 | 46.69% (287) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_2598 | - | 1e-101 | 64.54% (282) | carveol dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_4801 | - | 1e-84 | 56.79% (280) | carveol dehydrogenase |
| M. ulcerans Agy99 | MUL_3392 | fabG | 7e-49 | 39.57% (278) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_2006 | - | 2e-86 | 56.38% (282) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2771|M.bovis_AF2122/97 ---MIDRPLEGKVAFITGAARGLGRAHAVRLAADGANIIAVDICEQ-IAS
Rv2750|M.tuberculosis_H37Rv ---MIDRPLEGKVAFITGAARGLGRAHAVRLAADGANIIAVDICEQ-IAS
MUL_3392|M.ulcerans_Agy99 MSRPLDGPLSGRVAFITGAARGQGRAHALRLARDGADVIAVDLCDQ-IAS
MAB_0072c|M.abscessus_ATCC_199 ----MTGRLTGKVALVTGAARGIGRAQAVRFAQEGADIIALDICAP-VHT
MMAR_4754|M.marinum_M MTEQLGGRVAGKVAFITGAARGQGRSHAVRLAQEGADIIAVDVCKPIVEN
TH_3929|M.thermoresistible__bu -MN----RLTGKVVAITGAARGQGRSHAVHMADEGADIIALDICAD-IAT
MAV_2598|M.avium_104 -MG----RVQDKVVLVTGGARGQGRSHAVKLAEEGADIILFDICHD-IET
MSMEG_4801|M.smegmatis_MC2_155 -MGSAEGRVAGKVAFITGAARGQGRSHAVRLAEEGADIIAVDLCQD-IDS
Mflv_4148|M.gilvum_PYR-GCK MTG----KLEGKVAFITGAARGQGRAHAIAMAREGADIIAVDICRD-IPS
Mvan_2006|M.vanbaalenii_PYR-1 -MG----KLDNKVAVVSGAARGQGRSHAVSLAAEGAHIIALDICAD-LEG
MLBr_01094|M.leprae_Br4923 -----MEGFAGKVAVVTGAGSGIGQALAIELARSGAKLAISDVDGE----
. .:*. ::*.. * *:: *: :* .**.: *:
Mb2771|M.bovis_AF2122/97 VPYPLSTADDLAATVELVEDAGGGIVARQGDVRDRASLSVALQAGLDEFG
Rv2750|M.tuberculosis_H37Rv VPYPLSTADDLAATVELVEDAGGGIVARQGDVRDRASLSVALQAGLDEFG
MUL_3392|M.ulcerans_Agy99 VPYPLGTAEELATTVKLVEDTGARIVASQADVRDREALAAALQAGIDELG
MAB_0072c|M.abscessus_ATCC_199 TITPPATRADLDKTSELVESAGRRVIPGVVDVRNLRDVQTFTQDAVTEFG
MMAR_4754|M.marinum_M TTIPASTPEDLAETADLVKGHNRRIFTAEADVRDYDALKAAVDAGVDELG
TH_3929|M.thermoresistible__bu NEYPLATREDLEETARLVEKAGRRAITAEVDVRDRARLKQVLDDAVAELG
MAV_2598|M.avium_104 NEYPLATSRDLEEAGLEVEKTGRKAYTAEVDVRDRAAVSRELANAVAEFG
MSMEG_4801|M.smegmatis_MC2_155 IGYSLATPEDLEETARYVEKAGRRIVTAQADVRDAAQLKEALERGVSELG
Mflv_4148|M.gilvum_PYR-GCK NPYPLATPDDLAETERSVKETGRRVVARVADVRERHELREAVEAGVVDFG
Mvan_2006|M.vanbaalenii_PYR-1 NTYPLSRPEDLDETARLAEKEGVRVHTAIVDVRERAAVWKAVADGVDALG
MLBr_01094|M.leprae_Br4923 ---------GLAQTEGQLKAIGASARTDRLDVTEREAFLTYADVVHENFG
* : : . . ** : . :*
Mb2771|M.bovis_AF2122/97 RLDIVVANAGIA-----MMQAGDDGWRDVIDVNLTGVFHTVQVAIPTLIE
Rv2750|M.tuberculosis_H37Rv RLDIVVANAGIA-----MMQAGDDGWRDVIDVNLTGVFHTVQVAIPTLIE
MUL_3392|M.ulcerans_Agy99 QVDIVVANAGIA-----PMQSGDDGWRDVIDVNLSGAYYTVEVAIPTMIE
MAB_0072c|M.abscessus_ATCC_199 GLDIVCATAGITSRRMLLDMP-ESDWQTMLDVNLTGVWHTTRAATPHLIA
MMAR_4754|M.marinum_M RLDIIVANAGIGNGGATLDKTSEHDWQEMIDVNLSGVWKSVKAAVPHLIA
TH_3929|M.thermoresistible__bu GLHVVVANAGICPQ---GNHLPYKAYIDAFDVDFVGVVNTIHVGLDYLGE
MAV_2598|M.avium_104 KLDVVVANAGICPL---GAHLPVQAFADAFDVDFVGVINTVHAALPYLTS
MSMEG_4801|M.smegmatis_MC2_155 KLDIVVAQAGIAAM---KGNPPLQAWTDGINTNLVGTINAIQVALPHLSE
Mflv_4148|M.gilvum_PYR-GCK KIDIVVANAGILPMA--MGNPDPMGFVDASDVDLVGVMNTVAVAIPHLPD
Mvan_2006|M.vanbaalenii_PYR-1 RLDIVVANAGICPMG--RGQ-TIQSWSDAIDTDLVGVFNVIQASLPHVND
MLBr_01094|M.leprae_Br4923 KVNQIYNNAGIAFTG-DVEVSHFKDIERVMDVDYWGVVNGTKAFLPYLIS
:. : *** :.: *. . :
Mb2771|M.bovis_AF2122/97 QGTGGSIVLISSAAGLVGIGSSDPGS-------LGYAAAKHGVVGLMRAY
Rv2750|M.tuberculosis_H37Rv QGTGGSIVLISSAAGLVGIGSSDPGS-------LGYAAAKHGVVGLMRAY
MUL_3392|M.ulcerans_Agy99 QGRGGSIVLISSAAGLVGISSADAGA-------IGYVASKHALVGLMRVY
MAB_0072c|M.abscessus_ATCC_199 RG-GGAMVLVSSIAGLRGLVGVS-----------HYVAAKHGVVGLMRSL
MMAR_4754|M.marinum_M GGNGGSIVLTSSVGGMKAYPHCG-----------NYVAAKHGVVGLMRSF
TH_3929|M.thermoresistible__bu GG---SVIVTGSIAGLVDQKDMANGGGPSGPGGAGYGMAKKMVRDYTKAL
MAV_2598|M.avium_104 GA---SIITTGSVAGLIAAAQPPGAGGPQGPGGAGYSYAKQLVDSYTLQL
MSMEG_4801|M.smegmatis_MC2_155 GA---SIVATASAAALMDAHNKPNPG--ADPGGMGYMVSKRMISEYVHYL
Mflv_4148|M.gilvum_PYR-GCK GA---SVIVTGSTAGMIRGTTTSPDM---GPGGAGYGWSKRIVIEYIEEM
Mvan_2006|M.vanbaalenii_PYR-1 GA---SIIATGSLAAQLG---SATNQ---GPGGSAYSLAKQVVAHYVNDL
MLBr_01094|M.leprae_Br4923 SG-DGHVINISSVFGLFSVPGQA-----------AYNSAKFAVRGFTEAL
. :: .* . * :* :
Mb2771|M.bovis_AF2122/97 --ANHLAPQNIRVNSVHPCGVDTPMINNEFFQQWLT-----------TAD
Rv2750|M.tuberculosis_H37Rv --ANHLAPQNIRVNSVHPCGVDTPMINNEFFQQWLT-----------TAD
MUL_3392|M.ulcerans_Agy99 --ANLLAPHSIRVNSLHPSGVDPPMINNEFIRHWLAD---------LVAE
MAB_0072c|M.abscessus_ATCC_199 --AIELAPHKIRVNTVHPTNVDTPMIQNEFVRTLFRPDL----EQPTRED
MMAR_4754|M.marinum_M --AVELGQHMIRVNSVHPTHVRTPMLHNEGTFKMFRPDL----ENPGPDD
TH_3929|M.thermoresistible__bu --ALTLAPHKIRINAVHPTNVNTDMLHNMSMYRVFRPDL----TEPTRED
MAV_2598|M.avium_104 --AAQLAPQSIRANVIHPTNVNTDMLNSAPMYRQFRPDL----EAPSRAD
MSMEG_4801|M.smegmatis_MC2_155 --ATELTPLGIRANVIHPTNCNTDMLQSEPMYRSFRPDL----EHPTRAD
Mflv_4148|M.gilvum_PYR-GCK --SLQLAPRMIRVNGIHPTNCNTHLLQNEGMYGVFRPDLKMEGKTPTRED
Mvan_2006|M.vanbaalenii_PYR-1 --SIQLAKRMIRVNAIHPTNVNTDMLHNEGLYRVFRPDL----KEPTREE
MLBr_01094|M.leprae_Br4923 REEMALAGRPVNVTTVYPGGIKTAIARNATAAEGLDVSK-----IASRFD
* :. . ::* . : .. : :
Mb2771|M.bovis_AF2122/97 MDAPHNLGNALPVELVQPTDIANAVAWLASEEARYVTGVTLPVDAGFVNK
Rv2750|M.tuberculosis_H37Rv MDAPHNLGNALPVELVQPTDIANAVAWLASEEARYVTGVTLPVDAGFVNK
MUL_3392|M.ulcerans_Agy99 TGSGPGAGNALPVQILQADDIAGALAWLVSDEARYITGVALPVDAGCVNK
MAB_0072c|M.abscessus_ATCC_199 FAAAAKTMNLLDLPWVEPLDIANASLFLASDEARYITSVSLPVDAGSTQR
MMAR_4754|M.marinum_M MAPICQLFHTLPIPWVEAEDISNAVLFLASDESRYITGVTLPVDAGGCLK
TH_3929|M.thermoresistible__bu AEVVFPLLQAMPIPYVEPDDVSHAVVYLASDESRYVTGQQLFVDAGAGLK
MAV_2598|M.avium_104 ALLAFPAMQAMPTPYVEASDISNAVCFLASDESRYVTGLQFKVDAGAMLK
MSMEG_4801|M.smegmatis_MC2_155 AEPVFYVQQAMKVPWVEPSDISNAVLWLASDESRFVTGMQLRVDAGGYLK
Mflv_4148|M.gilvum_PYR-GCK AEPLFSLFQAMPIPYIEPEDMANLGVFLASDDSRYITGQQIRVDAGSLLK
Mvan_2006|M.vanbaalenii_PYR-1 AEEAFPAMQAMPIPYIEPRDVSNAVVFLAGDDSRYITGTQLRIDAGGYVK
MLBr_01094|M.leprae_Br4923 TWVAHTSPQHAARIILKAVRKKKARVLVGPDAKVANVVVRFSGGAGYQRL
: ::. : : . : .**
Mb2771|M.bovis_AF2122/97 R------------
Rv2750|M.tuberculosis_H37Rv R------------
MUL_3392|M.ulcerans_Agy99 R------------
MAB_0072c|M.abscessus_ATCC_199 -------------
MMAR_4754|M.marinum_M -------------
TH_3929|M.thermoresistible__bu MGV----------
MAV_2598|M.avium_104 F------------
MSMEG_4801|M.smegmatis_MC2_155 WYDYHV-------
Mflv_4148|M.gilvum_PYR-GCK WPNGLGG------
Mvan_2006|M.vanbaalenii_PYR-1 AVPWKG-------
MLBr_01094|M.leprae_Br4923 FAQVASRLILNQR