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AHPVPIGGPRADRARRVADVLRQQIHADAYPDGLPAELELAAEFSVSRNTIREALAVLKREGLIDRGPRV GTHVAQRKYDHALDALLGLKETFKDLGEVRNEVRAAMPVTAPPSVARRLRLAPGEQAVFIERLRYLGELP LSLDLTYLAPPIGRQVLEHSLETNDVFALIEQVSGQRLGSAALALEAIPADAHSAATLQVPDGAALLMLE RLTSLADGTPVDLEYIRMRGDRITMRGNLFRAEPMRSNS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3402 | - | - | 100% (250) | GntR-family protein transcriptional regulator |
| M. avium 104 | MAV_5032 | - | 9e-41 | 47.53% (223) | GntR-family protein transcriptional regulator |
| M. avium 104 | MAV_0738 | - | 2e-13 | 27.39% (241) | mercuric reductase/transcriptional regulator, fusion |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0816c | - | 7e-15 | 27.66% (235) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0447 | - | 9e-15 | 28.76% (233) | regulatory protein GntR, HTH |
| M. tuberculosis H37Rv | Rv0792c | - | 7e-15 | 27.66% (235) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2239 | - | 2e-96 | 73.55% (242) | GntR family transcriptional regulator |
| M. marinum M | MMAR_2560 | - | 4e-15 | 30.80% (237) | GntR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_1227 | - | 3e-41 | 48.77% (203) | transcriptional regulator, GntR family protein |
| M. thermoresistible (build 8) | TH_3932 | - | 2e-14 | 29.06% (234) | PUTATIVE transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_3201 | - | 2e-15 | 30.80% (237) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0056 | - | 9e-16 | 28.23% (209) | UbiC transcription regulator-associated domain-containing |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0816c|M.bovis_AF2122/97 MTS----VKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLP
Rv0792c|M.tuberculosis_H37Rv MTS----VKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLP
MMAR_2560|M.marinum_M MTSDEDSPRHDLADADLRVTRGSVPASVQLAELLRTQILERALSPGSRLP
MUL_3201|M.ulcerans_Agy99 MTSDEDSPRHDLADADLRVTRGSVPASVQLAELLRTQILERALSPGSRLP
MAV_3402|M.avium_104 ------------MAHPVPIGGPRADRARRVADVLRQQIHADAYPDG--LP
MAB_2239|M.abscessus_ATCC_1997 ----------MAAAEPTPLRRPRADQARLVADVLRHQIHAGGYAEGG-LP
MSMEG_1227|M.smegmatis_MC2_155 ---------------------------MLRGKILDGVYGGLAAARPM-LP
Mflv_0447|M.gilvum_PYR-GCK ----------------------MPPAYQVLRERLRDEIAAGCYPDGTRLP
TH_3932|M.thermoresistible__bu -----MTRTATPMRSTTINRFADRPLYRQLSEVLEARLIERARPGDR-LP
Mvan_0056|M.vanbaalenii_PYR-1 ---------------------MNVPKPYLVRTGLDGILDG--LQEGDPFP
* :*
Mb0816c|M.bovis_AF2122/97 SERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQGLGTFVADP--VEQELS
Rv0792c|M.tuberculosis_H37Rv SERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQGLGTFVADP--VEQELS
MMAR_2560|M.marinum_M TEQELIARSGVSRSTVRAAVGILEDEGWLVRRQGLGTFVAEP--VKQDLE
MUL_3201|M.ulcerans_Agy99 TEQELIARSGVSRSTVRAAVGILEDEGWLVRRQGLGTFVAEP--VEQDLE
MAV_3402|M.avium_104 AELELAAEFSVSRNTIREALAVLKREGLIDRGPRVGTHVAQR--KYDHAL
MAB_2239|M.abscessus_ATCC_1997 SEHALAAEFFVSRNTVREALTTLKDEGLIERGPRTGTHVALR--KYEHGL
MSMEG_1227|M.smegmatis_MC2_155 PENELAAEFGVSRNAIREALELLRGEGLITRVQGAGTFVTGA--KLSQRI
Mflv_0447|M.gilvum_PYR-GCK TESELVARLGLSRQTVRRAFQDLVAEGAVYRVPGRGSYAGDR--GRRYLR
TH_3932|M.thermoresistible__bu SEAELSGQFGVNRLTVRRALHELAQRGIIETVHGRGSFVARQPVRYRLSA
Mvan_0056|M.vanbaalenii_PYR-1 PERELAARFGVARETVRQALHELLVEGRIER-RGRGTVVSRP---KLVQP
.* * . : * ::* *. * .* : *: .
Mb0816c|M.bovis_AF2122/97 CGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGLVE---VLCIRR
Rv0792c|M.tuberculosis_H37Rv CGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGLVE---VLCIRR
MMAR_2560|M.marinum_M SGVRTITEVLLSRGVTPRVEVLSHAVVAAPQSVGAALGRSE---VLRIQR
MUL_3201|M.ulcerans_Agy99 SGVRTITEVLLSRGVTPRVEVLAHAVVAAPQSVGAALGRSE---VLRIQR
MAV_3402|M.avium_104 DALLGLKETFKDLG-EVRNEVRAAMPVTAPPSVARRLRLAPGEQAVFIER
MAB_2239|M.abscessus_ATCC_1997 DALLGLKETFKGYG-EVRNEVRVIQEVNAPPAVAHRLRLDPGARVIFIER
MSMEG_1227|M.smegmatis_MC2_155 DRLEGLAESLAGHQLPVENTVLSVRESVASPFVAAKLQLPEGAPILFIER
Mflv_0447|M.gilvum_PYR-GCK --QLGSIEDLLSLSEDTTMEVLDGLRRRVDIDAASRLRLDGDVVYTVVFR
TH_3932|M.thermoresistible__bu TRDASFTRGMRELGHPVRIEVLGAETTRCRR---LRTELHTAGEVLTTTT
Mvan_0056|M.vanbaalenii_PYR-1 LSLRSYTEGAQRMGRTPGRLLVTWENITVDAEIAAALDVSPSARVMHLER
. :
Mb0816c|M.bovis_AF2122/97 RIRTGDQPLALVTAYLPPGVG-PAVEP--LLSGSADTETTYAMWERRLGV
Rv0792c|M.tuberculosis_H37Rv RIRTGDQPLALVTAYLPPGVG-PAVEP--LLSGSADTETTYAMWERRLGV
MMAR_2560|M.marinum_M RYSESDQPLAIVTCYLPADLPHDAVEP--LLSATSATATTYTMWEQRLGV
MUL_3201|M.ulcerans_Agy99 RYSESDQPLAIVTCYLPTDLPHDAVEP--LLSATSVTATTYTMWEQRLGV
MAV_3402|M.avium_104 LRYLGELPLSLDLTYLAPPIGRQVLEH--SLE----TNDVFALIEQVSGQ
MAB_2239|M.abscessus_ATCC_1997 LRYLGDLPLSLDKTYLTPDVGEAVIEH--QLE----TNDVFALIERVTGR
MSMEG_1227|M.smegmatis_MC2_155 LRSVGGVPLSLDTTSLR--LGAVSVDD--NLD----RQDVFALIERELGM
Mflv_0447|M.gilvum_PYR-GCK RLHDG-IAFGHTMVHLPPAVAAPVLASPHLMTGAVSTHTVIGLLEPHLER
TH_3932|M.thermoresistible__bu LRHVDGQPWSVSVTSIALDRFPGIAQQ------WSGSTSLFDFLWQTFGV
Mvan_0056|M.vanbaalenii_PYR-1 VLLADDVRIGLESTYLPRHRFGDLEQH------FDPTTSLYSAIRAR-GV
. . :
Mb0816c|M.bovis_AF2122/97 RIAQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKPLEVVVF
Rv0792c|M.tuberculosis_H37Rv RIAQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKPLEVVVF
MMAR_2560|M.marinum_M RISSATHEIQAAGASPEIAAALGLSEGAPVLVLRRTSYTDGDKPLEVVLF
MUL_3201|M.ulcerans_Agy99 RISSATHEVQAAGASPEIASALGLSEGAPVLVLRRTSYTDGDKPLEVVLF
MAV_3402|M.avium_104 RLGSAALALEAIPADAHSAATLQVPDGAALLMLERLTSLADGTPVDLEYI
MAB_2239|M.abscessus_ATCC_1997 RLGSANLALEAVAADSHSAATLQVPDSAPLLLLERLTHLDDGTPVDLEYI
MSMEG_1227|M.smegmatis_MC2_155 RLGWAEMTVESVSADADTAKLLQIRSGAPLLLLHRLTHLEDGTPFDFETV
Mflv_0447|M.gilvum_PYR-GCK PIDEAAQSITVVSADEAAAAAVHCAPGHPMLRVDRLYADDEGRPVELAVS
TH_3932|M.thermoresistible__bu RMRRAYRSFSAVLADLAEAQHLGLRTGAPVLEMRGLNVDQHGAPVAVVRH
Mvan_0056|M.vanbaalenii_PYR-1 KFGSATERIETVLPSPREAELLESTTAMPMLLLNRRSVDVDGVPIEVVRA
: * . .. * : . .:* : . *. .
Mb0816c|M.bovis_AF2122/97 HHRPERYQFSVTLPRTLPGSGAGIIEKRDFA
Rv0792c|M.tuberculosis_H37Rv HHRPERYQFSVTLPRTLPGSGAGIIEKRDFA
MMAR_2560|M.marinum_M HHRPERYEFCVTLPRTMPGQRAGMTER----
MUL_3201|M.ulcerans_Agy99 HHRPERYEFCVTLPRTMPGQRAGMTER----
MAV_3402|M.avium_104 RMRGDRITMRGNLFRAEPMRSNS--------
MAB_2239|M.abscessus_ATCC_1997 RMRGDRITLRSNLLRDI--------------
MSMEG_1227|M.smegmatis_MC2_155 RYRGDRCTLMTTAARGVDDPPQAPQEPPQ--
Mflv_0447|M.gilvum_PYR-GCK QFLPEQYTYRVTLRRSG--------------
TH_3932|M.thermoresistible__bu RFRGDRVELTVDLA-----------------
Mvan_0056|M.vanbaalenii_PYR-1 LYRGDRVAFEATLDDR---------------
::