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TAPVRGRPRDPDADRAILQAALDLFIERGVEGSSIEQIAKRAGVGKPTVYRRWGTKEELIAAAMETLVAE EVGWTSPEAIETRSPHVLVEAAIDSAAAATAAPYYRALVARVYGSAVSHPELMTVYWDRYILPRRVQATR LLERARELGTVAADTDLDVAIDMMVGAITYRVLRPNPPDVDEMRRYLREVYRQAGLLPPG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5008 | - | - | 100% (201) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1535 | - | 8e-16 | 29.21% (178) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3506 | - | 2e-13 | 30.57% (193) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3192c | - | 5e-13 | 30.34% (178) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3167c | - | 5e-13 | 30.34% (178) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02568 | - | 5e-07 | 26.51% (166) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4749c | - | 2e-16 | 29.55% (176) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0340 | - | 9e-14 | 29.17% (168) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4057 | - | 1e-14 | 30.05% (183) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1500 | - | 6e-92 | 84.85% (198) | TetR family protein transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_4110 | - | 2e-63 | 56.35% (197) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_4780 | - | 1e-13 | 29.17% (168) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0778 | - | 8e-84 | 78.35% (194) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5008|M.gilvum_PYR-GCK ---------MTAPVRGRPRDPDADRAILQAALDLFIERGVEGSSIEQIAK
MSMEG_1500|M.smegmatis_MC2_155 ---------MTGPGRGRPRDAAADRAILHAALDLFIERGVEGTSIEQIAR
Mvan_0778|M.vanbaalenii_PYR-1 ---------MTAS-RGRPRDAGADVAILRAGLELFIERGVEGTSMEQIAR
TH_4110|M.thermoresistible__bu VTATDAAATGRAAARGRPRDPALDSAILDAALEIFVEQGISALSIEQVAR
Mb3192c|M.bovis_AF2122/97 -MKADLPSLDKAPGAGRPRDPRIDSAILSATAELLVQIGYSNLSLAAVAE
Rv3167c|M.tuberculosis_H37Rv -MKADLPSLDKAPGAGRPRDPRIDSAILSATAELLVQIGYSNLSLAAVAE
MAV_4057|M.avium_104 -MKADPSGLDKAPGAGRPRDPRIDSAILSATAELLVQTGYSNISLAAVAE
MMAR_0340|M.marinum_M -MVAD---------FGRPRDPRIDGAVLRATVELLAETGYAGLLVSAIAK
MUL_4780|M.ulcerans_Agy99 -MVAD---------FGRPRDPRIDGAVLRATVELLAETGYAGLLVSAIAK
MAB_4749c|M.abscessus_ATCC_199 ----MNGTRPRQPRRGRRPTEEVREEVLQAAGELLFTEGMGGFTIDKVAA
MLBr_02568|M.leprae_Br4923 ----------MAGGAKRIPRAVREQQMLDAAVQMFSVNGYHKTSMDAIAA
* :* * ::: * : :*
Mflv_5008|M.gilvum_PYR-GCK RAGVGKPTVYRRWGTKEELIAAAMETLVAEEVGWTSPEAIETRSPHVLVE
MSMEG_1500|M.smegmatis_MC2_155 RAGVGKPTIYRRWSTKEDLIAAAMETLVAEEVVWASPEEIESRSPHVLVE
Mvan_0778|M.vanbaalenii_PYR-1 KAGVGKPTIYRRWATKEELISAAMETLVVAETGWASPEAIATESPYELVE
TH_4110|M.thermoresistible__bu RAGVGKPTIYRRWSDKEQLVADAIEHRVSAELAWPTPAEASVSDPYELVR
Mb3192c|M.bovis_AF2122/97 RAGTTKSALYRRWSSKAELVHEAAFPAAPTALQAAAG------DIAADIR
Rv3167c|M.tuberculosis_H37Rv RAGTTKSALYRRWSSKAELVHEAAFPAAPTALQAAAG------DIAADIR
MAV_4057|M.avium_104 RAGTTKSALYRRWSSKAELVHEAAFPTAPTALEAPAG------DIAADMR
MMAR_0340|M.marinum_M RAGTSKPAIYRRWPSKAHLVHEAVFPIDAATAVPDTG------SPVDDLR
MUL_4780|M.ulcerans_Agy99 RAGTSKPAIYRRWPSKAHLVHEAVFPIDAATAVPDTG------SPVDDLR
MAB_4749c|M.abscessus_ATCC_199 LSGASKMTIYKWWPSKGALALDGYFRKVEPDLNFPDSG-----EIERDLR
MLBr_02568|M.leprae_Br4923 EAQISKPMLYLYYGSKEDLFGACLNREMSRFIAMVRADIDFTQSPKDLLR
: * :* : * * . :.
Mflv_5008|M.gilvum_PYR-GCK AAIDSAAAATAAPYYRALVARVYGS-AVSHPELMTVYWDRYILPRRVQAT
MSMEG_1500|M.smegmatis_MC2_155 AAIESAAATTASPSYRALVARVYGS-AVSHPGLMAVYWDRYILPRRAQAR
Mvan_0778|M.vanbaalenii_PYR-1 AAIEGAAVATTTPQYRALVARVFGS-AVSHPELMATYWRRYILPRRRLAA
TH_4110|M.thermoresistible__bu RNISAAARTAADPAFRGLIAAIYGS-AVTHPALLRTYWEHYILPRRTAAI
Mb3192c|M.bovis_AF2122/97 MMIAATRDVFTTPVVRAALPGLVAD-MTADAELNARVLARFADLF-AAVR
Rv3167c|M.tuberculosis_H37Rv MMIAATRDVFTTPVVRAALPGLVAD-MTADAELNARVLARFADLF-AAVR
MAV_4057|M.avium_104 MMIEATRDVFTTPVVRAALPGLVAD-MTADPALNARVMSRFADLF-TAVR
MMAR_0340|M.marinum_M EMVRRTTAVLSTPAAKAALPGLIGE-MAADPTLHSALLVRFGEIFGHGLT
MUL_4780|M.ulcerans_Agy99 EMVRRTTAVLSTPAAKAAQPGLIGE-MAADPTLHSALLVRFGEIFGHGLT
MAB_4749c|M.abscessus_ATCC_199 AQMRAFLGVIRDTAAGAIIGELIGQ-AQVDPELKAAFLQRYSGPRRALAV
MLBr_02568|M.leprae_Br4923 NTIVSFLRYIDANRASWIVMYIQAMSLPAFAQTVREARDQITELVAGLMR
: : . . :
Mflv_5008|M.gilvum_PYR-GCK RLLERARELGTVAADTDLDV-AIDMMVGAITYRVLRPN---PPDVDEMRR
MSMEG_1500|M.smegmatis_MC2_155 RLLERARELGTVSEDTDLDV-AIDMMVGAITYRVLQPD---PPDVDGMRR
Mvan_0778|M.vanbaalenii_PYR-1 ALLERARELGTVAADANPDV-AIDMMVGAVTYRVLQPD---PPDVDEMRR
TH_4110|M.thermoresistible__bu ALLRRARDLGTVAADADLDV-LVDMLAGAVTYRVLQPE---PPSARQLRC
Mb3192c|M.bovis_AF2122/97 MRLREAVDRGEAHPDVDPDR-LIELIGGATMLRMLLYP---DDMLDDAWV
Rv3167c|M.tuberculosis_H37Rv MRLREAVDRGEAHPDVDPDR-LIELIGGATMLRMLLYP---DDMLDDAWV
MAV_4057|M.avium_104 VRLGEAVDRGEAHPDVDPDR-LIELIGGATMLRMLLRP---EEELDDAWV
MMAR_0340|M.marinum_M TWLDNAAARGQVRADVTAPE-LAEAIAGIVLIGLLTRPGELEPGVGDAWI
MUL_4780|M.ulcerans_Agy99 TWLDNAAARGQVRADVTAPE-LAEAIAGIVLIGLLTRPGELEPGVGDAWI
MAB_4749c|M.abscessus_ATCC_199 AAIRRAQERGQLRANVDPEV-MVDQLWGACYHRLLVPD----QPLTAGFV
MLBr_02568|M.leprae_Br4923 VGTRSSRPDHEYEIMAGALVGAGEAMATRLTTGDIAVDEAAELMINLFWH
: . : : :
Mflv_5008|M.gilvum_PYR-GCK YLREVYRQAGLLPPG------
MSMEG_1500|M.smegmatis_MC2_155 YLRAVYRQIGLLS--------
Mvan_0778|M.vanbaalenii_PYR-1 YLREVYRQVGLLPD-------
TH_4110|M.thermoresistible__bu YLEVAYRQVGLLP--------
Mb3192c|M.bovis_AF2122/97 DQTTAIVVRGVHRAAPGGSVV
Rv3167c|M.tuberculosis_H37Rv DQTTAIVVRGVHRAAPGGSVV
MAV_4057|M.avium_104 EQTTAIVVHGVRR--------
MMAR_0340|M.marinum_M DRTTTLLLKGIRKGTPQ----
MUL_4780|M.ulcerans_Agy99 DRTTTLLLKGIRKGTPQ----
MAB_4749c|M.abscessus_ATCC_199 DALLDNLFKGIGA--------
MLBr_02568|M.leprae_Br4923 GLKGAPADRDFGPSIVAG---
..