For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTTHSTDGRADATRQQILRAASHQFARRPYHDVGLDDILAEAELTKGAMYFHFKSKHALAVAIIESQTAS GAVAVQDLLTRGLSGLETLIDFSYLIAVKDIKTDLVRSGLNLMESVGLSDGLQEKLFDRWIKALARVAEQ AKGEGDINEHCDPQDIGRLMVSLHMGLRKTSNLDDPERFLRDLEKCWSLLLTGILQPDRTEYFQQFLRRR AALAINTSATDDDES
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1140 | - | - | 100% (225) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_1141 | - | 6e-20 | 30.48% (210) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_3517 | - | 9e-08 | 28.32% (113) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2534 | - | 2e-06 | 34.02% (97) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1640 | - | 7e-08 | 38.98% (59) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2506 | - | 2e-06 | 34.02% (97) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 2e-06 | 36.23% (69) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4912c | - | 9e-10 | 30.66% (137) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0630 | - | 8e-08 | 25.95% (185) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_2195 | - | 4e-61 | 52.61% (211) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0452 | - | 8e-07 | 41.82% (55) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_4890 | - | 2e-07 | 36.25% (80) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4729 | - | 2e-06 | 33.75% (80) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_1140|M.avium_104 ----------------------MTTHSTDGRADAT-----RQQILRAASH
MSMEG_2195|M.smegmatis_MC2_155 -----------------------MTEQLDRRADLT-----RLQILQAASR
Mb2534|M.bovis_AF2122/97 ------------MTASAPDGRPGQPEATNRRSQLKS--DRRFQLLAAAER
Rv2506|M.tuberculosis_H37Rv ------------MTASAPDGRPGQPEATNRRSQLKS--DRRFQLLAAAER
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
TH_0452|M.thermoresistible__bu MSEVADTTARQEITPTNGGTTSGAAAGANRRGNRLPRDERRNQLLIAASE
Mflv_1640|M.gilvum_PYR-GCK -----------------------MPQPVRQQARTSVR---KQQLSQAAAR
MAB_4912c|M.abscessus_ATCC_199 ------------MTEAGAKPRRGRPPASDGDAAAT-----RQRIMEVATD
MUL_4890|M.ulcerans_Agy99 --------------------MESKRRTQEERSAAT-----REALITAARK
MMAR_0630|M.marinum_M ---------------------MARPRAFD-----------EAVVLSAARD
Mvan_4729|M.vanbaalenii_PYR-1 -----------------------MPRVVKPKDVR------RAEVLDRALA
. : *
MAV_1140|M.avium_104 QFARRPYHDVGLDDILAEAELTKGAMYFHFKSKHALAVAIIESQTASGAV
MSMEG_2195|M.smegmatis_MC2_155 QFARTPYSLVSLDDILADAQVTKGALYFHFRSKHALACAIVEYHAAQARD
Mb2534|M.bovis_AF2122/97 LFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVSARLLA
Rv2506|M.tuberculosis_H37Rv LFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVSARLLA
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
TH_0452|M.thermoresistible__bu VFVDRGYHAAGMDEIAERAGVSKPVLYQHFSSKLELYLAVLQRHVDNLVS
Mflv_1640|M.gilvum_PYR-GCK LFTDRGYHNVSMDDIASAVGLTGPALYRHFRKKHDILMQVISEQLGAVEA
MAB_4912c|M.abscessus_ATCC_199 LFAEKGFHATGVAEIGAAAGVRGGALYYHIGSKEELLWEILRSYIDEMLT
MUL_4890|M.ulcerans_Agy99 LWGSRGYAEVGTPEIAAEAGVTRGAMYHQFADKAALFGEVVEAVEQDVMT
MMAR_0630|M.marinum_M EFRSHGYAATSVDSLAAATGLNRSSLYGSFGDKHRLFLRALDGYCEATLH
Mvan_4729|M.vanbaalenii_PYR-1 LFLERGYENVSLNDLLAVSGTSKGAFYHYFPSKEALVVALAQRSAGEAFE
: : . .: :* : .* :
MAV_1140|M.avium_104 AVQDLL-TRG---LSGLETLIDFSYLIAVKD--IKTDLVRSGLNLMESVG
MSMEG_2195|M.smegmatis_MC2_155 TTEDVA-ARN---LSGLETLIDISYQLAVDD--VSDPMTRAGLNLIESIG
Mb2534|M.bovis_AF2122/97 GARDVT-TRSANLAAALDGLIEFHLDFALGE--ADLIRIQD-RDLAHLPA
Rv2506|M.tuberculosis_H37Rv GARDVT-TRSANLAAALDGLIEFHLDFALGE--ADLIRIQD-RDLAHLPA
MLBr_00815|M.leprae_Br4923 SVQQAL-RTTTNNRQRLHAAVQAFFDFIEHD--GQGYRLIFENDNITEPR
TH_0452|M.thermoresistible__bu GVRQAL-RTTTDNRQRLRAAVQAFFDFIEHD--GQGYRLIFENDYVTEPQ
Mflv_1640|M.gilvum_PYR-GCK VAARAV-DAGPTDERAEVFLAALADLLLERE--QVLLWKRERRQLAEEAQ
MAB_4912c|M.abscessus_ATCC_199 EAVHIA-NMNTEPARRLRTLIGSYVILIVKY--RKQVAIQVRDGSALTGE
MUL_4890|M.ulcerans_Agy99 RMATSV-TTSGAATPADAIRAAVDAWLEVSG--DPEVRQLILLDAPAVLG
MMAR_0630|M.marinum_M DVREVLRERGVSARQRLINHVHAIVNGIVAD--TDRRGCMMSRSSAELAG
Mvan_4729|M.vanbaalenii_PYR-1 VLRPVFDQPGKNALERLNAGLAASYQVKLGMGVPEPIAAMRSLLMPENQA
MAV_1140|M.avium_104 LSDGLQEKLFDRWIKALARVAEQAKGEG--------------------DI
MSMEG_2195|M.smegmatis_MC2_155 RTENLGAKVVTDWVARFSAIGRRAVSEG--------------------DL
Mb2534|M.bovis_AF2122/97 VAERQVRKAQRQYVEVWVGVLR--------------------------EL
Rv2506|M.tuberculosis_H37Rv VAERQVRKAQRQYVEVWVGVLR--------------------------EL
MLBr_00815|M.leprae_Br4923 VAAQVRVATESCIDAVFALISA----------------------------
TH_0452|M.thermoresistible__bu VAAQVKVATEACTDAVFDLISQ----------------------------
Mflv_1640|M.gilvum_PYR-GCK RQCRLKLSDVLRLSSQALGLTSGEKPSGQAELRTWAVLGIYSSVAPIRNR
MAB_4912c|M.abscessus_ATCC_199 RAAQLQG-LRDELQRCWQRVFDEG--------------------------
MUL_4890|M.ulcerans_Agy99 WAGFCDVAQRYSLGMTEQLITEAIR-------------------------
MMAR_0630|M.marinum_M ADPDVSGIVERSLEAWRRELADCIAEAQ---------------------L
Mvan_4729|M.vanbaalenii_PYR-1 LFRKIVTIWEDLFRPVLTEVITQGVREG-----------------VFDTF
:
MAV_1140|M.avium_104 NEHCDPQDIGRLMVSLHMGLRKTSNLDDPERFLRDLEKCWSLLLTGILQP
MSMEG_2195|M.smegmatis_MC2_155 TPDSDPDVVARLLVSLYLGVRQTSELEDPQRFLQDLERSWQLVLPGIANP
Mb2534|M.bovis_AF2122/97 NPG-LAEADARLMAHAVFGLLNSTPHS---------------MKAADSKP
Rv2506|M.tuberculosis_H37Rv NPG-LAEADARLMAHAVFGLLNSTPHS---------------MKAADSKP
MLBr_00815|M.leprae_Br4923 -DSRLDPHRARMVAVGLVGISVDCARY------------WLDTNRPISKS
TH_0452|M.thermoresistible__bu -DSGLEAHRARMIAVGLVAISVDCARY------------WLHADRPISKE
Mflv_1640|M.gilvum_PYR-GCK VENATAKRLLRAAALNILGCELDTGLPRSATPVTHRRQPPGRRERILSTA
MAB_4912c|M.abscessus_ATCC_199 HEVGTFHTADHVLTNAILGMLNMVAVWY--------------RTDGKSPA
MUL_4890|M.ulcerans_Agy99 -AGQLDRHPVRPLAHVLIGALDEAAMF----------------IATADDP
MMAR_0630|M.marinum_M EGAVAGDGSPQALATVMLSLMQGFEALG----------------KGGVGS
Mvan_4729|M.vanbaalenii_PYR-1 DPEGVGDMIQGFAASIQDYLVRMFDAADAKSRRKTIDDCVKRLKLYGIAT
.
MAV_1140|M.avium_104 DRTEYFQQFLRRRAALAINTSATDDDES----------------------
MSMEG_2195|M.smegmatis_MC2_155 DRLGYLRQFIRRRTTLTARKAVPLHPEPPAHTRAGSA-------------
Mb2534|M.bovis_AF2122/97 ARTVRARAVLRAMTVAALSAADRCL-------------------------
Rv2506|M.tuberculosis_H37Rv ARTVRARAVLRAMTVAALSAADRCL-------------------------
MLBr_00815|M.leprae_Br4923 DAVEGTVQFAWGGLSHVPLTRL----------------------------
TH_0452|M.thermoresistible__bu DAVEGTVQFAWGGLSHVPLTRS----------------------------
Mflv_1640|M.gilvum_PYR-GCK GRLFHAQSYHAVGIEEIAAESDTAIATFYQYFNGKGELLHALLNRGAEGL
MAB_4912c|M.abscessus_ATCC_199 QIAKRIADMVLDGIHVDRPEEHAEQAPTDRK-------------------
MUL_4890|M.ulcerans_Agy99 KRARRESRQVLRRLIDGMLND-----------------------------
MMAR_0630|M.marinum_M AELRAAESAALALLFGAGTDPKP---------------------------
Mvan_4729|M.vanbaalenii_PYR-1 DRILGLPDGATVVLERKQVEAMMTLFMPSRPAGSLP--------------
MAV_1140|M.avium_104 --------------------------------------------------
MSMEG_2195|M.smegmatis_MC2_155 --------------------------------------------------
Mb2534|M.bovis_AF2122/97 --------------------------------------------------
Rv2506|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00815|M.leprae_Br4923 --------------------------------------------------
TH_0452|M.thermoresistible__bu --------------------------------------------------
Mflv_1640|M.gilvum_PYR-GCK HYVTNHRLASAATAQDALDTVASTLIELALGPHQPILAILAADLVYLPDA
MAB_4912c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_4890|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0630|M.marinum_M --------------------------------------------------
Mvan_4729|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1140|M.avium_104 --------------------------------------------------
MSMEG_2195|M.smegmatis_MC2_155 --------------------------------------------------
Mb2534|M.bovis_AF2122/97 --------------------------------------------------
Rv2506|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00815|M.leprae_Br4923 --------------------------------------------------
TH_0452|M.thermoresistible__bu --------------------------------------------------
Mflv_1640|M.gilvum_PYR-GCK ARELIRMSEREYTDEWVAALVGVCPELTPPHARLLARAAIGLITDITQIQ
MAB_4912c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_4890|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0630|M.marinum_M --------------------------------------------------
Mvan_4729|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1140|M.avium_104 ----------------------
MSMEG_2195|M.smegmatis_MC2_155 ----------------------
Mb2534|M.bovis_AF2122/97 ----------------------
Rv2506|M.tuberculosis_H37Rv ----------------------
MLBr_00815|M.leprae_Br4923 ----------------------
TH_0452|M.thermoresistible__bu ----------------------
Mflv_1640|M.gilvum_PYR-GCK KMRMRPGIATELHQLVNAVLAA
MAB_4912c|M.abscessus_ATCC_199 ----------------------
MUL_4890|M.ulcerans_Agy99 ----------------------
MMAR_0630|M.marinum_M ----------------------
Mvan_4729|M.vanbaalenii_PYR-1 ----------------------