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MARQVRSEATRQKILDSAIEVFGEVGYAAAGWSTIIERTGMTKGALYHHFDSKESLASNIIEEGSDRLLS AFRNVCGSSSPGLENLVHGTFTIVEVLRSDKMVRAAAQLATALSGFNGAASRFYANLVLETAQEARRAIK EGDLRDDIDPDVLSASLMGTIFGARLIASTISGHGRIGDIIGDPTARLHQIWSLLLPGIVSQASLPYFEQ FLRREGMRHATANPGAEPEGE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1141 | - | - | 100% (231) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_1140 | - | 6e-20 | 30.48% (210) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_3305 | - | 6e-09 | 29.38% (177) | HTH-type transcriptional repressor AcnR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0080 | - | 9e-09 | 24.71% (174) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3666 | - | 5e-10 | 27.59% (174) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3557c | - | 1e-08 | 26.99% (163) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 4e-07 | 27.42% (124) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4352c | - | 2e-11 | 25.15% (163) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1444 | - | 5e-10 | 33.62% (116) | TetR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_2193 | - | 4e-46 | 41.41% (227) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0251 | - | 9e-11 | 27.38% (168) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_1483 | - | 2e-08 | 28.34% (187) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_2744 | - | 5e-10 | 28.16% (174) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_1141|M.avium_104 ------------------------------MARQVRSEATRQKILDSAIE
MSMEG_2193|M.smegmatis_MC2_155 ------------------------------MARQARAGVTRRKIITAAVD
Mflv_3666|M.gilvum_PYR-GCK ----------------------------MPRVTDDHLAARRRQILDGARR
Mvan_2744|M.vanbaalenii_PYR-1 ----------------------------MPRVTDDHLAARRRQILDGARR
TH_0251|M.thermoresistible__bu -------------------------------VTDDHLAARRRQILDGARR
MUL_1483|M.ulcerans_Agy99 ----------------------------MPKVSEDHLAARRRQILDGARR
MAB_4352c|M.abscessus_ATCC_199 ----------------------------MVPLRQAQALATRQRLVDVATE
Mb0080|M.bovis_AF2122/97 -------------------------MEIKRRTQEERSAATREALITGARK
MMAR_1444|M.marinum_M ----------------------------------MRAASTRERLVTEAMR
Rv3557c|M.tuberculosis_H37Rv -----------------------------MDRVAGQVNSRRGELLELAAA
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
* :: *
MAV_1141|M.avium_104 VFGEVGYAAAGWSTIIERTGMTKG--ALYHHFDSKESLASNIIEEGSDR-
MSMEG_2193|M.smegmatis_MC2_155 LFAEIGYPATGLGEIIERADMTKG--ALYYHFDSKEALAEAIIAESGAS-
Mflv_3666|M.gilvum_PYR-GCK CFAEYGYESATVRRLEQTIGLSRG--AIFHHFRDKDTLFFELAREDAER-
Mvan_2744|M.vanbaalenii_PYR-1 CFAEYGYDRATVRRLEQTIGLSRG--AIFHHFRDKDTLFFELAREDAER-
TH_0251|M.thermoresistible__bu CFAEYGYEQATVRRLEQATGLSRG--AIFHHFKDKDTLFFELAREDAER-
MUL_1483|M.ulcerans_Agy99 CFAEYGYDKATVRRLEQAIGMSRG--AIFHHFRDKDALFFALAHEDAER-
MAB_4352c|M.abscessus_ATCC_199 LFALHGFTSVTTTSLSEASGMTRG--ALYHHFANMTEVMEAVFERAEGF-
Mb0080|M.bovis_AF2122/97 LWGLRGYAEVGTPEIATEAGVTRG--AMYHQFADKAALFRDVVEVVEQD-
MMAR_1444|M.marinum_M LFGERGYHATSVAQIEAAAGLASGSGALYHHFDSKESLLEAGIDRQLDRR
Rv3557c|M.tuberculosis_H37Rv MFAERGLRATTVRDIADGAGILSG--SLYHHFASKEEMVDELLRGFLDW-
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKP--VLYQHFSSKLELYLAVLERHMNN-
: * . : .: :: :* . :
MAV_1141|M.avium_104 -LLSAFRNVCGSS---SPGLENLVHGTFTIVEVLRSDKMVRAAAQLATAL
MSMEG_2193|M.smegmatis_MC2_155 -MLAAFQNITETS---SPALENLIHGLFVVCDFTRTDRVADIGLHLLQTF
Mflv_3666|M.gilvum_PYR-GCK -MADVAA---------REGLIQVMRDMLAAPDQFDWLATRLEIARKLRND
Mvan_2744|M.vanbaalenii_PYR-1 -MADVAA---------REGLIQVMRDMLAAPDQFNWLATRLEIARKLRND
TH_0251|M.thermoresistible__bu -MAEVAS---------REGLIQVMRDLIAAPEQYDWLTTRLEIARKLRND
MUL_1483|M.ulcerans_Agy99 -MADVAS---------REGLIQVMRDMLAAPEQFDWLATRLEIARKLRND
MAB_4352c|M.abscessus_ATCC_199 -LVAEVNHSLTSI---ESPAERFLAIGSAVLDVLAREPIVQRIVFVEAPM
Mb0080|M.bovis_AF2122/97 -VMARMATLVAASG--AATPADAIRAAVDAWLEVSGDPEVRQLVLLDAPV
MMAR_1444|M.marinum_M RAMGDLRALFAGLG--DPRSELTLLGRYVLAVLDEESQLLQIAAALPTGR
Rv3557c|M.tuberculosis_H37Rv -LFARYRDIVDSTANPLERLQGLFMASFEAIEHHHAQVVIYQDEAQRLAS
MLBr_00815|M.leprae_Br4923 -LVSSVQQALRTT---TNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDNI
MAV_1141|M.avium_104 S-GFNGAASRFYANLVLETAQEARRAIKEGDLRDDIDPDVLSASLMGTIF
MSMEG_2193|M.smegmatis_MC2_155 A-GINDTTARVYASWLDAISAQLHRAAAEGDLREGLDPGAVADVVLSALL
Mflv_3666|M.gilvum_PYR-GCK P-AFSQGWAERSAELSAATTERLRRQKQAGRLRDDVDGEVLRTYLELVLD
Mvan_2744|M.vanbaalenii_PYR-1 P-AFSRGWAERSAELSAATTERLRRQKRAGRLRDDVPGDVLRTYLELVLD
TH_0251|M.thermoresistible__bu P-EFHRGWSELSAELAAATTARLRRQKQAGRLRDDVPGEVLRTYLELVLD
MUL_1483|M.ulcerans_Agy99 P-EFSRGWAERSAELAAATTDRLRRQKQANRVRDDVPNEVLQCYLDLVLD
MAB_4352c|M.abscessus_ATCC_199 ALGWSRWRALDGGRSLGLIQDILEELYRRGELVEAVDPQMAAQLILGAIN
Mb0080|M.bovis_AF2122/97 VLGWAGFRDVAQRYSLGMTEQLITEAIRAGQLAR-QPVRPLAQVLIGALD
MMAR_1444|M.marinum_M PAQLDDAYAALFAGLNAELTDWVKELVPTISKQQALTIGTVAVNSLFGNR
Rv3557c|M.tuberculosis_H37Rv QPRFSYIEDR-NKQQRKMWVDVLNQGIEEGYFRPDLDVDLVYRFIRDTTW
MLBr_00815|M.leprae_Br4923 T--EPRVAAQVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGISVD
MAV_1141|M.avium_104 GARLIASTISGHGRIGDIIGDPTARLHQIWSLLLPGIVSQASLPYFEQFL
MSMEG_2193|M.smegmatis_MC2_155 GAEALT-------RAGTSGTDLRERLVRTWDLLLPALVEPASLDYFREFL
Mflv_3666|M.gilvum_PYR-GCK GLVARLAS-----------GDDPEKLSAVLDLVEASVRQP----------
Mvan_2744|M.vanbaalenii_PYR-1 GLVARLAS-----------GDDPEKLGAVLDLVEASVRQQ----------
TH_0251|M.thermoresistible__bu GLVARLAS-----------GDDPEKLSAVLDLVEASVRHQGSE-------
MUL_1483|M.ulcerans_Agy99 GLVARLAS-----------GEDPQRLTDVLDLVENSLRRS----------
MAB_4352c|M.abscessus_ATCC_199 ESGMYAAAAP---------SERSSRAAEQLTLLCRGLLSPRSG-------
Mb0080|M.bovis_AF2122/97 EAAMFIAT-----------ADDPKRARRETRQVLRRLIDGMLNG------
MMAR_1444|M.marinum_M ATSTVFRTP-------VADLTDEQYIAEWATMLVNRIELLRKL-------
Rv3557c|M.tuberculosis_H37Rv VSVRWYRPGG--------PLTAQQVGQQYLAIVLGGITKEGV--------
MLBr_00815|M.leprae_Br4923 CARYWLDTNR--------PISKSDAVEGTVQFAWGGLSHVPLTRL-----
:
MAV_1141|M.avium_104 RREGMRHATANPGAEPEGE
MSMEG_2193|M.smegmatis_MC2_155 ARESMRRS---PGTD----
Mflv_3666|M.gilvum_PYR-GCK -------------------
Mvan_2744|M.vanbaalenii_PYR-1 -------------------
TH_0251|M.thermoresistible__bu -------------------
MUL_1483|M.ulcerans_Agy99 -------------------
MAB_4352c|M.abscessus_ATCC_199 -------------------
Mb0080|M.bovis_AF2122/97 -------------------
MMAR_1444|M.marinum_M -------------------
Rv3557c|M.tuberculosis_H37Rv -------------------
MLBr_00815|M.leprae_Br4923 -------------------