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TEQLDRRADLTRLQILQAASRQFARTPYSLVSLDDILADAQVTKGALYFHFRSKHALACAIVEYHAAQAR DTTEDVAARNLSGLETLIDISYQLAVDDVSDPMTRAGLNLIESIGRTENLGAKVVTDWVARFSAIGRRAV SEGDLTPDSDPDVVARLLVSLYLGVRQTSELEDPQRFLQDLERSWQLVLPGIANPDRLGYLRQFIRRRTT LTARKAVPLHPEPPAHTRAGSA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2195 | - | - | 100% (233) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2193 | - | 4e-25 | 33.33% (204) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6807 | - | 1e-07 | 28.41% (176) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3192c | - | 3e-07 | 29.03% (186) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2460 | - | 3e-07 | 29.38% (177) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3167c | - | 3e-07 | 29.03% (186) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4648 | - | 2e-08 | 36.92% (65) | TetR family transcriptional regulator |
| M. marinum M | MMAR_2316 | - | 7e-07 | 28.22% (163) | transcriptional regulator |
| M. avium 104 | MAV_1140 | - | 3e-61 | 52.61% (211) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3297 | - | 7e-06 | 35.71% (84) | PUTATIVE transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4787 | - | 3e-05 | 21.05% (190) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4729 | - | 5e-08 | 29.58% (142) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2195|M.smegmatis_MC2_155 -----------------MTEQLDRRADLTR-------LQILQAASRQFAR
MAV_1140|M.avium_104 ----------------MTTHSTDGRADATR-------QQILRAASHQFAR
Mb3192c|M.bovis_AF2122/97 --------------MKADLPSLDKAPGAGRPRDPRIDSAILSATAELLVQ
Rv3167c|M.tuberculosis_H37Rv --------------MKADLPSLDKAPGAGRPRDPRIDSAILSATAELLVQ
MAB_4648|M.abscessus_ATCC_1997 -----------------MATRRQMYAEQTR-------SDLLDSARRHFTT
MMAR_2316|M.marinum_M -------------------MCSADLTAKAR---------IRNAAVARFAR
Mflv_2460|M.gilvum_PYR-GCK ---------------MVERWTRERRLEHTR-------SVLLDAAEEVFAE
MUL_4787|M.ulcerans_Agy99 MNERTPSSRPHRSSRSRDSPSREERKEATR-------RAIIAAALKLVHD
Mvan_4729|M.vanbaalenii_PYR-1 ------------------MPRVVKPKDVRR-------AEVLDRALALFLE
TH_3297|M.thermoresistible__bu -------------MDSDAAAPGVRKSDRTR-------LTILDAARVAFAR
* : : .
MSMEG_2195|M.smegmatis_MC2_155 TPYSLVSLDDILADAQVTKGALYFHFRSKHALACAIVEYHAAQARDTTED
MAV_1140|M.avium_104 RPYHDVGLDDILAEAELTKGAMYFHFKSKHALAVAIIESQTASGAVAVQD
Mb3192c|M.bovis_AF2122/97 IGYSNLSLAAVAERAGTTKSALYRRWSSKAELVHEAAFPAAPTALQAAAG
Rv3167c|M.tuberculosis_H37Rv IGYSNLSLAAVAERAGTTKSALYRRWSSKAELVHEAAFPAAPTALQAAAG
MAB_4648|M.abscessus_ATCC_1997 TGYNSVTVDDIVSSIEVSKGTFYYHFSDKQAMFTALLTECLTETADTVTT
MMAR_2316|M.marinum_M DGFQKVNLRAIATSAGVSEALIFHHFGSKDGLRAACDEYVLNVLVGRART
Mflv_2460|M.gilvum_PYR-GCK KGFTPATLDDIARAAGYTKGAIYKHFDTKEELFLAVSDRYWRRYFDNFAE
MUL_4787|M.ulcerans_Agy99 RSFSALSLREVTREAGIVPAAFYRHFESMEALGLVLIDESFRTLRDTLRG
Mvan_4729|M.vanbaalenii_PYR-1 RGYENVSLNDLLAVSGTSKGAFYHYFPSKEALVVALAQRSAGEAFEVLRP
TH_3297|M.thermoresistible__bu KGFSGVTIRDITDLAGVTRANFYYYFKDKTELFVELGTATYREVLEVIET
: : : . :: : :
MSMEG_2195|M.smegmatis_MC2_155 ----VAARNLSGLETLIDISYQLAVDDVSDPMTRAGLN-LIESIGRTENL
MAV_1140|M.avium_104 ----LLTRGLSGLETLIDFSYLIAVKDIKTDLVRSGLN-LMESVGLSDGL
Mb3192c|M.bovis_AF2122/97 ----DIAADIR-------MMIAATRDVFTTPVVRAALPGLVADMTADAEL
Rv3167c|M.tuberculosis_H37Rv ----DIAADIR-------MMIAATRDVFTTPVVRAALPGLVADMTADAEL
MAB_4648|M.abscessus_ATCC_1997 GIRLLDKPGANGPQVAATSAWVYLSRSLHDRTYRELMR-QAPMVLGEETY
MMAR_2316|M.marinum_M -----AGRPTA-------MADLLGVYLSNPEEYRLQVQYMARAIEDDAPA
Mflv_2460|M.gilvum_PYR-GCK -----------------VMSSASRVGADELDEIAERWRQLSIDRGAEHAA
MUL_4787|M.ulcerans_Agy99 -------ARAGRLDPNRVIESSVEILIGSVAERREHWRFIVRERSTGLSV
Mvan_4729|M.vanbaalenii_PYR-1 VFDQPGKNALERLNAGLAASYQVKLGMGVPEPIAAMRSLLMPENQALFRK
TH_3297|M.thermoresistible__bu FS-DTASPVIIDQWVSRYFTYLDRNGAFVIRSEEDMPQDGAFRTAVARSH
MSMEG_2195|M.smegmatis_MC2_155 GAKVVTDWVARFSAIGRRAVSEGDLTPDSDPDVVARLLVSLYLGVR-QTS
MAV_1140|M.avium_104 QEKLFDRWIKALARVAEQAKGEGDINEHCDPQDIGRLMVSLHMGLR-KTS
Mb3192c|M.bovis_AF2122/97 NARVLARFADLFAAVRMRLREAVDRGE-AHPDVDPDRLIELIGGAT-MLR
Rv3167c|M.tuberculosis_H37Rv NARVLARFADLFAAVRMRLREAVDRGE-AHPDVDPDRLIELIGGAT-MLR
MAB_4648|M.abscessus_ATCC_1997 RHIDETIVLPPLVTLMDTLAARGELKAGVHTHMAARMLMTMFVTANSIIA
MMAR_2316|M.marinum_M AGTFVDTMVEESEAIFRAGAADGSMRPSSDPRALAVLNLLVALGLLTMAP
Mflv_2460|M.gilvum_PYR-GCK LGLEFTLYLLRNPEARERVEAKRAEVVDQLAEFIVEGMSQLGATLLIEPS
MUL_4787|M.ulcerans_Agy99 LRYAIRTDIRLITSELATDLARFPGLNEWSTEDLNILATMFVNAMIVTAE
Mvan_4729|M.vanbaalenii_PYR-1 IVTIWEDLFRPVLTEVITQGVREGVFDTFDPEGVGDMIQGFAASIQDYLV
TH_3297|M.thermoresistible__bu RRAAQALGQQIAKASSTPLAADEAATGLVVMAMLERSWLIHHNGVFDAPR
MSMEG_2195|M.smegmatis_MC2_155 ELEDPQRF------LQD--LERSWQLVLPGIANPDRLGYLRQFIRRRTTL
MAV_1140|M.avium_104 NLDDPERF------LRD--LEKCWSLLLTGILQPDRTEYFQQFLRRRAAL
Mb3192c|M.bovis_AF2122/97 MLLYPDDM------LDDAWVDQTTAIVVRGVHRAAPGGSVV---------
Rv3167c|M.tuberculosis_H37Rv MLLYPDDM------LDDAWVDQTTAIVVRGVHRAAPGGSVV---------
MAB_4648|M.abscessus_ATCC_1997 ESDDPATT------MTE--VADTIATMFSGIVLGDVPLSRAAANG-----
MMAR_2316|M.marinum_M PMARALGH------EHFG-PEVLQRMAVPALELYTRGLYTDDTLAKAAQD
Mflv_2460|M.gilvum_PYR-GCK TFARALVA------TSDS-VVLGSQLDAVDLYRPMVEMYVSVIKLPD---
MUL_4787|M.ulcerans_Agy99 AIEDAQSS------EALEEIRRIAVKQLRMVAIGVAGWKSRP--------
Mvan_4729|M.vanbaalenii_PYR-1 RMFDAADAKSRRKTIDDCVKRLKLYGIATDRILGLPDGATVVLERKQVEA
TH_3297|M.thermoresistible__bu DVVLAAASEVIRRLVEDDGRPGTSIQEILPRVSVEPQRCRDGTQLEPGRA
.
MSMEG_2195|M.smegmatis_MC2_155 TARKAVPLHPEPPAHTRAGSA-----------
MAV_1140|M.avium_104 AINTSATDDDES--------------------
Mb3192c|M.bovis_AF2122/97 --------------------------------
Rv3167c|M.tuberculosis_H37Rv --------------------------------
MAB_4648|M.abscessus_ATCC_1997 --------------------------------
MMAR_2316|M.marinum_M AWVARRAPQQEG--------------------
Mflv_2460|M.gilvum_PYR-GCK --------------------------------
MUL_4787|M.ulcerans_Agy99 --------------------------------
Mvan_4729|M.vanbaalenii_PYR-1 MMTLFMPSRPAGSLP-----------------
TH_3297|M.thermoresistible__bu PAQQALASHRHASGSTWPHRPEVIRATGRTQT