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TRRPHPGDSTTRDLLIDATIKVMVEDGYAAATSRRVAAEAGVKPALVHYYFPTMDELYLDVFRRGAAAYQ ERQTRALTSDRPLHALWDTLIEPKDTRLLLEFMGLANHRKAIRAELAAWFGRWRDTQITALNSIVREHDM DAGEFPPAGIAVILAAIGRMLILEDALGATAGHDAAVALVNRFIDRFELP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0367 | - | - | 100% (191) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_0847 | - | 4e-42 | 50.57% (176) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_0966 | - | 1e-41 | 44.92% (187) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0335 | - | 4e-07 | 26.06% (165) | TetR/AcrR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1588 | - | 3e-42 | 51.11% (180) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0328 | - | 4e-07 | 26.06% (165) | TetR/AcrR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4089c | - | 1e-08 | 33.33% (114) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4693 | - | 2e-43 | 45.45% (187) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_4779 | - | 1e-40 | 43.85% (187) | regulatory protein |
| M. thermoresistible (build 8) | TH_2883 | - | 4e-51 | 52.08% (192) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_0675 | - | 1e-08 | 28.31% (166) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5169 | - | 1e-42 | 51.43% (175) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0335|M.bovis_AF2122/97 MQ------------QQRTNRDKLLDGALACLRERGYGNTSSRDIARAAGV
Rv0328|M.tuberculosis_H37Rv MQ------------QQRTNRDKLLDGALACLRERGYGNTSSRDIARAAGV
MAV_0367|M.avium_104 MT-----RRPHPG--DSTTRDLLIDATIKVMVEDGYAAATSRRVAAEAGV
TH_2883|M.thermoresistible__bu MSSSSPSRRSRVGGSDTATRRALIKATADVMLEEGYAAATSRRVAARAGV
Mflv_1588|M.gilvum_PYR-GCK MP-----AAAKSRPAD--ARGRLIEATAKVMRDEGYAAATSRRVAAEAGV
Mvan_5169|M.vanbaalenii_PYR-1 MA-----ASPKGRGSDPNARQRLIEATARVMRDEGYAAATSRRVAAEAGV
MMAR_4693|M.marinum_M MT-----SARRIGAPDAKNRGVLLDTAEELMIEEGYAAVTSRRVASEAGL
MSMEG_4779|M.smegmatis_MC2_155 MA-----SARRIGAPDAKNRIVLLDAAEALMIDEGYAAVTSRRVAERAGL
MUL_0675|M.ulcerans_Agy99 MP--------TAAERGAQTRAALMAAAVAVIAERGWGAATTRMVAERAGL
MAB_4089c|M.abscessus_ATCC_199 MSGR--PRRISPIREGNSTRDEILDASAELFTTDGFAATTTRRIAESVGI
* * :: : : *:. .::* :* .*:
Mb0335|M.bovis_AF2122/97 NIASINYHFGSKDALLDDALGRCFSTWNQRVQEAFDHSRAAGPAGQILAV
Rv0328|M.tuberculosis_H37Rv NIASINYHFGSKDALLDDALGRCFSTWNQRVQEAFDHSRAAGPAGQILAV
MAV_0367|M.avium_104 KPALVHYYFPTMDELYLDVFR-------RGAAAYQERQTRALTSDRPLHA
TH_2883|M.thermoresistible__bu KPALVHYYFPSMDDLFVAVFR-------AGAEATLQRQRNAFAGDRPLHA
Mflv_1588|M.gilvum_PYR-GCK KQALVYYYFPTMDDLFVEVLR-------VGGESSLEHMRAALTNDDPLRA
Mvan_5169|M.vanbaalenii_PYR-1 KQALVYYYFPTMDDLFVEVLR-------AGGESALEHMRAALTNDDPLHA
MMAR_4693|M.marinum_M KPQLVHYYFRTMEELFLELFR-------RRAEEGLRAQAQALQSPKPLWA
MSMEG_4779|M.smegmatis_MC2_155 KPQLVHYYFRTMDDLFLAVFR-------RRAEEGLAAQARALDSPQPLWA
MUL_0675|M.ulcerans_Agy99 PPGLVHYHFASLNDLLIDAALQAAREEAAQVLDGLAGDSSSQGIDRLIDA
MAB_4089c|M.abscessus_ATCC_199 QQASLYYHFKTKDDILDALLAMTIDQP-LHYAALIADRPEAPVVRLYALA
: *:* : : : : .
Mb0335|M.bovis_AF2122/97 LEATVDSFEQIRPAVYACVESYAPALRSEALRERLAAGYADVRQHSVDLA
Rv0328|M.tuberculosis_H37Rv LEATVDSFEQIRPAVYACVESYAPALRSEALRERLAAGYADVRQHSVDLA
MAV_0367|M.avium_104 LWDTLIEPKDTR----LLLEFMGLANHRKAIRAELAAWFGRWRDTQITAL
TH_2883|M.thermoresistible__bu LWE-LNSTQGAQ----LFMEFMALGNHRKAIRREIAAYAEQYGELEHAAV
Mflv_1588|M.gilvum_PYR-GCK LWLINSEAGRTG----LNAEFMALANHRKAIRVELKAYAERVRDIETAAV
Mvan_5169|M.vanbaalenii_PYR-1 LWLINNDASRTG----LNTEFMALANHRKAIRVELRAYAERVRDIETAAV
MMAR_4693|M.marinum_M LWRLGSDPAFAR----ISMEFMALANHRKALRAEIAHYAERFRDEQRRVI
MSMEG_4779|M.smegmatis_MC2_155 LWRFGIDPSATR----LTMEIMGVANHRKALRTEIGRYAERFRDEQTKAM
MUL_0675|M.ulcerans_Agy99 VSSYDVDDRNQNPAILVFGEMLLAATRYERLRMGLAEILGDYRSTLRQWL
MAB_4089c|M.abscessus_ATCC_199 LGDAAQLAASRWNLGALYLLPDLRAERFSAFRRKRDQLRTHYQELAAAAC
: . : . :* .
Mb0335|M.bovis_AF2122/97 GAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWIADPSATPRSTEVIRAL
Rv0328|M.tuberculosis_H37Rv GAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWIADPSATPRSTEVIRAL
MAV_0367|M.avium_104 NSIVREHDMDAGEFPPAGIAVILAAIGRMLILEDALGATAGHDAAVALVN
TH_2883|M.thermoresistible__bu ATALRAHGMDTEEFPPAAIAMILTSVARIMLIEQNLGIERSHAAVREFVG
Mflv_1588|M.gilvum_PYR-GCK TVALRANGVDLQEHPPVVVSMLIAQIARSLCNEDAVGVTLGHEEMRAWVD
Mvan_5169|M.vanbaalenii_PYR-1 TVALRANGVDLDEHPPVVISMLIAQVARSLCNEVAVGVTLGHDEMRAYVE
MMAR_4693|M.marinum_M TAALQRYGVDSQDVPPVVWTVLMASLSRFLVLEKALGMSGGHAETIELVE
MSMEG_4779|M.smegmatis_MC2_155 TAALDRYGVNAADVPPIVWTFLATSVSRVMVMEQALGMSAGHAEVLEFCE
MUL_0675|M.ulcerans_Agy99 AD--QGGAIDPEATAALMFAAIDGLVLHRVIDPRLRTLAIRPTLRRLAGL
MAB_4089c|M.abscessus_ATCC_199 RASMLRAGVERLPFRLVESVIMLRADGDSIAPEALADATLRVVGVTGDAG
: : :
Mb0335|M.bovis_AF2122/97 ASIGAVVTSQLR----------
Rv0328|M.tuberculosis_H37Rv ASIGAVVTSQLR----------
MAV_0367|M.avium_104 RFIDRFELP-------------
TH_2883|M.thermoresistible__bu RYLDRFDVPAGAHDADS-----
Mflv_1588|M.gilvum_PYR-GCK RQLALLAAEPGG----------
Mvan_5169|M.vanbaalenii_PYR-1 RQLKLLAPVTGG----------
MMAR_4693|M.marinum_M SYLRRLEGEP------------
MSMEG_4779|M.smegmatis_MC2_155 GWLRRIEGEPLPIEAAG-----
MUL_0675|M.ulcerans_Agy99 PTAQTDERTPS-----------
MAB_4089c|M.abscessus_ATCC_199 EIEGAARVLLGQLGWPVAIPKR