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MSATPEGSSLADLLDSRRLFQFVVAAEAPTLAAAAADLFITQQALSSAIRQLERDLGVELFSRAQRSLQL TDAGHELYTGAKPLLAGIRVLANATRNISNPQRAFVIGHSPAISGEEVYRIIEPIVVADPTASITVRQVF PSTMRDGLLDGSLDLALRRGVDMPADLATDTLLYQPLRIAVVQSHPLAAQDYVDIGEIAEHPIVVWAPPR HSFYTDLLVSHCRRSGFEPRLLINPVQGTPPHTAVLAHPDHCAFVTDDPGNVYHRKVRVIEIANPPLVPV QAVWLPHSVSAIRTKLFAAVRESGVVSTPPRTEDGTIPGRSHVGYTSDVQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4658 | - | - | 100% (330) | LysR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4795c | - | 1e-63 | 45.10% (286) | LysR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2238 | - | 7e-17 | 27.85% (219) | LysR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2303c | - | 2e-07 | 28.50% (200) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1356 | - | 2e-19 | 29.36% (235) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2282c | - | 2e-07 | 28.50% (200) | LysR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02041 | oxyR | 5e-11 | 24.64% (211) | putative LysR-family transcriptional regulator |
| M. marinum M | MMAR_4157 | - | 5e-13 | 26.73% (217) | LuxR family transcriptional regulator |
| M. avium 104 | MAV_3102 | - | 2e-12 | 29.53% (193) | LysR substrate binding domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_4331 | - | 2e-55 | 42.81% (285) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_3504 | - | 4e-66 | 46.13% (284) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_4020 | - | 7e-13 | 26.51% (215) | LuxR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1027 | - | 2e-17 | 28.37% (215) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4157|M.marinum_M --------------------------MELYQLRYFQAVAECGTLRGASEQ
MUL_4020|M.ulcerans_Agy99 --------------------------MELYQLRYFQAVAECGTLRGASEQ
Mb2303c|M.bovis_AF2122/97 -------------------MPLSSRMPGLTCFEIFLAIAEAGSLGGAARE
Rv2282c|M.tuberculosis_H37Rv -------------------MPLSSRMPGLTCFEIFLAIAEAGSLGGAARE
MSMEG_4331|M.smegmatis_MC2_155 ----------------MP---------DLRRLRQFVAVADAGSVTAAAAA
TH_3504|M.thermoresistible__bu ----------------VPSPK-----IDLRRLAQFVAVAELGSFTRAAAT
MAB_4658|M.abscessus_ATCC_1997 -------------MSATPEGSSLADLLDSRRLFQFVVAAEAPTLAAAAAD
Mflv_1356|M.gilvum_PYR-GCK MVSAVTGRPTNDPPHTWRHRTIKEPPMELRHLRYFLAVAETCHFGQAAEQ
Mvan_1027|M.vanbaalenii_PYR-1 -------------------------MFSLARLSCFVAVAEELHFGRAAER
MLBr_02041|M.leprae_Br4923 -------------------MSDKSYQPTIAGLRAFVAVVEKGHFSAAASF
MAV_3102|M.avium_104 --------------------------MDTHRLKYFLRIAEQGSITGAAAS
: * .: . *:
MMAR_4157|M.marinum_M LLVSQSAVSRAITLLEAEIGVQLFTRRGRTNELNRYGQALLVGSRLAQRS
MUL_4020|M.ulcerans_Agy99 LLVSQSAVSRAITLLEAEIGVQLFTRRGRTNELNRYGQALLVGSRLAQRS
Mb2303c|M.bovis_AF2122/97 LGLTQQAVSRRLASMEAQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLEV
Rv2282c|M.tuberculosis_H37Rv LGLTQQAVSRRLASMEAQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLEV
MSMEG_4331|M.smegmatis_MC2_155 LHLSQQALSSSIQQLEKQLGATLFHREGRRLRLTRAGEVLLVEGRPLLAA
TH_3504|M.thermoresistible__bu LHLSQQALSSAVRALENDVGADLFTRDGRRISLTTAGRTLLAEGKPLLAA
MAB_4658|M.abscessus_ATCC_1997 LFITQQALSSAIRQLERDLGVELFSRAQRSLQLTDAGHELYTGAKPLLAG
Mflv_1356|M.gilvum_PYR-GCK LHIAQPALSYAIRQLENSLDATLFTRTTRHVALTPAGEFLRVEATRILNG
Mvan_1027|M.vanbaalenii_PYR-1 LHMTQPPLSRQVQQLENELGVQLIDRTTRNVTLTPAGAAFLPDARRILQL
MLBr_02041|M.leprae_Br4923 LGVRQSTLSQALAALESGLGVQLIERSTRRVFVTTQGRHLLPRAQAAIEA
MAV_3102|M.avium_104 LGIAQPALSRQIRLLEEDLGVALFRRTRRGVQLTEEGERLRASTAAPLRQ
* : * .:* : :* :.. * * * :. * .
MMAR_4157|M.marinum_M VSSAIDNVRELAGVSGGTVALGFLHSLGMQTVPHLIR-LHHSRFPQAR--
MUL_4020|M.ulcerans_Agy99 VSSAIDNVRELAGVSGGTVALGFLHSLGMQTVPHLIR-LHHSRFPQAR--
Mb2303c|M.bovis_AF2122/97 ADEIDAGLGSLRTEGRQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGTV
Rv2282c|M.tuberculosis_H37Rv ADEIDAGLGSLRTEGRQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGTV
MSMEG_4331|M.smegmatis_MC2_155 AHTIAARVEQTAHRADEAYVIGHTPALSGIEAYTHVERAITAFPDVSFTF
TH_3504|M.thermoresistible__bu ARTVAEHVRQTEAAAQAHYVIGHTPALSGAEAYALIEPAVTAYPSTSFTL
MAB_4658|M.abscessus_ATCC_1997 IRVLANATRNISN-PQRAFVIGHSPAISGEEVYRIIEPIVVADPTASITV
Mflv_1356|M.gilvum_PYR-GCK VDAAQRGVRRIAAGRSGLLRLGLTGTAAFSHLPKIARIVRQELPAVALDI
Mvan_1027|M.vanbaalenii_PYR-1 AEGAAQTVKRIPAGDLGTVVVGFTAASAHAVLPRLLERARERLPDVKLDL
MLBr_02041|M.leprae_Br4923 MDAFTAAAAGESDPLRGGMRLGLIPTVAPYVLPTMLTGLTHRLPTLTLRV
MAV_3102|M.avium_104 LELAMQYAGSPIARLARGVRLGILDTTVDVFAAHLLSSLAAAFPKVTFSV
: :
MMAR_4157|M.marinum_M --FELHQRSGQGVLSDLVSGVTDVS-LSFPAAFEGYGEIAWQTLFTQQLY
MUL_4020|M.ulcerans_Agy99 --FELHQRSGQGVLSDLVSGVTDVS-LSFPAAFEGYGEIAWQTLFTQQLY
Mb2303c|M.bovis_AF2122/97 PEVILTATNSEHAIAAVRDGIADLGFIENPCPPTGLGSVVVAR---DELV
Rv2282c|M.tuberculosis_H37Rv PEVILTATNSEHAIAAVRDGIADLGFIENPCPPTGLGSVVVAR---DELV
MSMEG_4331|M.smegmatis_MC2_155 R-QFYPD----ALVEAVLDGTVHLGLRRGVVPTSAVATAVLGF---DRVR
TH_3504|M.thermoresistible__bu R-QLYPD----ALTDAVFDGTVQLGLRRGVVPTPELATAVIGY---HRVR
MAB_4658|M.abscessus_ATCC_1997 R-QVFPS----TMRDGLLDGSLDLALRRGVDMPADLATDTLLY---QPLR
Mflv_1356|M.gilvum_PYR-GCK HADLLTP----DQCEGLRTGALDVGVLRPPAVGGDVATRTIAA---EPLV
Mvan_1027|M.vanbaalenii_PYR-1 R-EMVTA----AQIEGLMTGELDLGMARPPLKRPGLVSRPLLH---EQLL
MLBr_02041|M.leprae_Br4923 VEDQTEH-----LLTALREGALDAAMIALPVETAGIAEIPIYD---EDFV
MAV_3102|M.avium_104 ETGSTDQ-----LVEAMLKGAVDVAVINPVPD-DRIFYRDLLT---EDLV
: * . . . .
MMAR_4157|M.marinum_M AVVSTDHPLAGR-RLIRFPELAAYPFVVLD--RDHTLRRIVDAACARHG-
MUL_4020|M.ulcerans_Agy99 AVVSTDHPLAGR-RLIRFPELAAYPFVVLD--RDHTLRRIVDAACARHG-
Mb2303c|M.bovis_AF2122/97 VVVPPGHKWARRSRVVSARELAQTPLVTRE--PNSGIRDSLTAALRDTLG
Rv2282c|M.tuberculosis_H37Rv VVVPPGHKWARRSRVVSARELAQTPLVTRE--PNSGIRDSLTAALRDTLG
MSMEG_4331|M.smegmatis_MC2_155 LALPRDHRLAGKA-SVDISDVAGERIALWAPPGASYYSDFLMGACRRAG-
TH_3504|M.thermoresistible__bu VAFVDSHPLAARE-SVDITELAREQVALWAPPGTSYYSDFLMGACRRAG-
MAB_4658|M.abscessus_ATCC_1997 IAVVQSHPLAAQD-YVDIGEIAEHPIVVWAPPRHSFYTDLLVSHCRRSG-
Mflv_1356|M.gilvum_PYR-GCK LAVSADHRLAAEP-VVSLADLRSEPFIGYT-GQDSAVNDAVTRSCRAAG-
Mvan_1027|M.vanbaalenii_PYR-1 AALPEGHPLADMTRELTLIDLDGQDFVMYSPVQARYFNELLISTFTIAG-
MLBr_02041|M.leprae_Br4923 LALPPGHPLSGKR-RVPTTALAQLPLLLLD--EGHCLRDQTLDICRKSG-
MAV_3102|M.avium_104 VVGAATSGLDSGQ-MMPFTELVELPLVVPR--SHTGIGNVIENAALRRK-
. : : .
MMAR_4157|M.marinum_M ---IDPTLAFEGTDVGTLRGLIGANLGVGVLPQATARP----ADIIEIAI
MUL_4020|M.ulcerans_Agy99 ---IDPTPAFEGTDVGTLRGLIGANLGVGVLPQATARP----ADIIEIAI
Mb2303c|M.bovis_AF2122/97 EDMQQAPPVLELSSAAAVRAAVLAGAGPAAMSRLAIADDLAFGRLLAVDI
Rv2282c|M.tuberculosis_H37Rv EDMQQAPPVLELSSAAAVRAAVLAGAGPAAMSRLAIADDLAFGRLLAVDI
MSMEG_4331|M.smegmatis_MC2_155 --FEPDYVVSRVQGAATVAAPLTT-DAIAFVTAPAGAAMDGRVVVVDLQ-
TH_3504|M.thermoresistible__bu --FEPDYVVSRVQGAATVAAPLTT-GGIAFVTAAAGPTMNGRVQVVDLT-
MAB_4658|M.abscessus_ATCC_1997 --FEPRLLINPVQGTPPHTAVLAHPDHCAFVTDDPGNVYHRKVRVIEIA-
Mflv_1356|M.gilvum_PYR-GCK --FVPHREHS-APGTAVLLALVAADLGVSVVPASVRALPLHGVVFRDL--
Mvan_1027|M.vanbaalenii_PYR-1 --TTPRYVQY-VTQVHTMLVLVRSGIGIALVPASAATLHPEGVVFRTIGA
MLBr_02041|M.leprae_Br4923 --VQAELANTRAASLATAVQCVTGGLGVTLLPQSAAPVESVRSKLGLAQF
MAV_3102|M.avium_104 ---VKISWRIATDSLALTKRLVAAGLVYGVLPLSACLNEIDSNQLRYTPL
: :. .
MMAR_4157|M.marinum_M DDAQLVRPIAIGWIADRCLPSSAVAFRET---------------------
MUL_4020|M.ulcerans_Agy99 DDAQLVRPIAIGWIADRCLPSSAVAFRET---------------------
Mb2303c|M.bovis_AF2122/97 PALNLRRQLRAIWVGGRTPPAGAIRDLLS---------------------
Rv2282c|M.tuberculosis_H37Rv PALNLRRQLRAIWVGGRTPPAGAIRDLLS---------------------
MSMEG_4331|M.smegmatis_MC2_155 --PELLVGAQALWQRHTHSAIRDMLLADGRRDSHDEIQACVRDEAADDAQ
TH_3504|M.thermoresistible__bu --PPLLVPVQALWQRHTLSAIRDRILEG----------------------
MAB_4658|M.abscessus_ATCC_1997 --NPPLVPVQAVWLPHSVSAIRTKLFAAVRESGVVSTPPRTEDG------
Mflv_1356|M.gilvum_PYR-GCK -VDGGTVDLALAWRDGVDNPVVDAVVAVLAG-------------------
Mvan_1027|M.vanbaalenii_PYR-1 -FRERPVELDAVWRGDSTNP---ALLRVLKD-------------------
MLBr_02041|M.leprae_Br4923 AAPCPGRRIGLAFRSASGRSASYRQIAKIIG-------------------
MAV_3102|M.avium_104 TEPPLTHRVGVAATSNLELPREVTAKVGNILR-----------------E
.
MMAR_4157|M.marinum_M ----ALGCYGHRVSAAGV--------
MUL_4020|M.ulcerans_Agy99 ----AFGCYGHRDSAAGV--------
Mb2303c|M.bovis_AF2122/97 ----HITSRST---------------
Rv2282c|M.tuberculosis_H37Rv ----HITSRST---------------
MSMEG_4331|M.smegmatis_MC2_155 RQVLPPQGHDKGGRAGQRRG------
TH_3504|M.thermoresistible__bu ------LG------------------
MAB_4658|M.abscessus_ATCC_1997 ----TIPGRSHVGYTSDVQ-------
Mflv_1356|M.gilvum_PYR-GCK ----ALTSLDHPALQEQS--------
Mvan_1027|M.vanbaalenii_PYR-1 ----VLPQQEWTT-------------
MLBr_02041|M.leprae_Br4923 ----ELISTEHHVRLVA---------
MAV_3102|M.avium_104 ETAHLIKTGRWPARLLSPQPWDPAVT