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PEHSAGIWDDPVDLRRLQQFLSVAEHSGFTRAAQQLRLTQQAISQSVTNLEKQVGAKLFDRSGRHIALTP AGEVLRDGSVVLLAAAQTLVRQVQNTAAEQPRPFVVAHTPAITAEEVHQLLVPVRSALPNVSVTALQVFP NALEPAVIGGSADIALRRGIATPKNLASRVIGYHALRVAVPREHLLAERDSVALRDLRNERIIVWAPPGV SHYTDFILSTCRSAGFEPAFVINHVQGTPPVTAVLDNDGVAFVTAPTGPCLAGQVVVIDIVDPPQAPIQA IWLPHTQSAIRDALTSG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4795c | - | - | 100% (298) | LysR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4658 | - | 9e-64 | 45.10% (286) | LysR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3208c | - | 9e-22 | 33.77% (228) | LysR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2303c | - | 1e-14 | 27.67% (300) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1356 | - | 2e-28 | 32.11% (299) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2282c | - | 1e-14 | 27.67% (300) | LysR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02663 | oxyS | 1e-06 | 36.07% (61) | putative LysR family transcriptional regulator |
| M. marinum M | MMAR_3419 | - | 3e-15 | 27.70% (278) | LysR family transcriptional regulator |
| M. avium 104 | MAV_2151 | - | 9e-17 | 30.85% (201) | LysR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_4331 | - | 1e-68 | 46.45% (282) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_3504 | - | 5e-73 | 47.55% (286) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_2698 | - | 2e-15 | 27.70% (278) | LysR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1027 | - | 3e-23 | 28.31% (272) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3419|M.marinum_M -------------------MPLSPRMPELGSFEIFLAIAQTGSLGAAARE
MUL_2698|M.ulcerans_Agy99 -------------------MPLSPRMPELASFEIFLAIAQTGSLGAAARE
MAV_2151|M.avium_104 -------------------MPLSPRMPELASFEAFLAIAETGSLGRAARE
Mb2303c|M.bovis_AF2122/97 -------------------MPLSSRMPGLTCFEIFLAIAEAGSLGGAARE
Rv2282c|M.tuberculosis_H37Rv -------------------MPLSSRMPGLTCFEIFLAIAEAGSLGGAARE
MSMEG_4331|M.smegmatis_MC2_155 --------------MP-----------DLRRLRQFVAVADAGSVTAAAAA
TH_3504|M.thermoresistible__bu --------------VPSPKI-------DLRRLAQFVAVAELGSFTRAAAT
MAB_4795c|M.abscessus_ATCC_199 --------------MPEHSAGIWDDPVDLRRLQQFLSVAEHSGFTRAAQQ
Mflv_1356|M.gilvum_PYR-GCK MVSAVTGRPTNDPPHTWRHRTIKEPPMELRHLRYFLAVAETCHFGQAAEQ
Mvan_1027|M.vanbaalenii_PYR-1 -------------------------MFSLARLSCFVAVAEELHFGRAAER
MLBr_02663|M.leprae_Br4923 --------------------------MLFRQLEYFVAVAQERHFARAAER
: : *:::*: . **
MMAR_3419|M.marinum_M LGLTQQAVSKRLAAMEAHTGVTLAVRTTRGSQLTPAGLIVSEWAARLLEV
MUL_2698|M.ulcerans_Agy99 LGLTQQAVSKRLAAMEAHTGVTLAVRTTRGSQLTPAGLIVSEWAARLLEV
MAV_2151|M.avium_104 LGLTQQAISRRLATMEAQIGVTLAVRTTRGSQLTPAGLIVADWAARLLEV
Mb2303c|M.bovis_AF2122/97 LGLTQQAVSRRLASMEAQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLEV
Rv2282c|M.tuberculosis_H37Rv LGLTQQAVSRRLASMEAQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLEV
MSMEG_4331|M.smegmatis_MC2_155 LHLSQQALSSSIQQLEKQLGATLFHREGRRLRLTRAGEVLLVEGRPLLAA
TH_3504|M.thermoresistible__bu LHLSQQALSSAVRALENDVGADLFTRDGRRISLTTAGRTLLAEGKPLLAA
MAB_4795c|M.abscessus_ATCC_199 LRLTQQAISQSVTNLEKQVGAKLFDRSGRHIALTPAGEVLRDGSVVLLAA
Mflv_1356|M.gilvum_PYR-GCK LHIAQPALSYAIRQLENSLDATLFTRTTRHVALTPAGEFLRVEATRILNG
Mvan_1027|M.vanbaalenii_PYR-1 LHMTQPPLSRQVQQLENELGVQLIDRTTRNVTLTPAGAAFLPDARRILQL
MLBr_02663|M.leprae_Br4923 CYVSQPALSSAIAKLERELNVTLINRGHSFEGLTPEGERLVVWAKRILAE
::* .:* : :* .. * * ** * . . :*
MMAR_3419|M.marinum_M AQEIDAGLGSLRKEGRERIRVAASQTIAEQLMPHWLLALQDAAKRRGTTA
MUL_2698|M.ulcerans_Agy99 AQEIDAGLGSLRKEGRERIRVAASQTIAEQLMPHWLLALQDAAKRRGTTA
MAV_2151|M.avium_104 AHEIDAGLGSLRKEGRERIRVAASQTISEQLMPHWLLSLQAEATRRGEAA
Mb2303c|M.bovis_AF2122/97 ADEIDAGLGSLRTEGRQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGTV
Rv2282c|M.tuberculosis_H37Rv ADEIDAGLGSLRTEGRQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGTV
MSMEG_4331|M.smegmatis_MC2_155 AHTIAARVEQTAHRADEAYVIGHTPALSGIEAYTHVERAITAFP----DV
TH_3504|M.thermoresistible__bu ARTVAEHVRQTEAAAQAHYVIGHTPALSGAEAYALIEPAVTAYP----ST
MAB_4795c|M.abscessus_ATCC_199 AQTLVRQVQNTAAEQPRPFVVAHTPAITAEEVHQLLVPVRSALP----NV
Mflv_1356|M.gilvum_PYR-GCK VDAAQRGVRRIAAGRSGLLRLGLTGTAAFSHLPKIARIVRQELP----AV
Mvan_1027|M.vanbaalenii_PYR-1 AEGAAQTVKRIPAGDLGTVVVGFTAASAHAVLPRLLERARERLP----DV
MLBr_02663|M.leprae_Br4923 HDAFKAEVHAVRSGITGTLRLGTVPTASTTAS-LVLSAFCSEHP----LI
: : : :
MMAR_3419|M.marinum_M PQVILTATNSDHAIAAVRDGTADLGFVENPGPPTGLGSRVVGHDDLVVVV
MUL_2698|M.ulcerans_Agy99 PQVILTATNSDHAIAAVRDGTADLGFVENPGPPTGLGSRVVGHDDLVVVV
MAV_2151|M.avium_104 PQVILTATNSEHAIASVRDGSADLGFVENPGTPKGLGSCVVGEDELVIVV
Mb2303c|M.bovis_AF2122/97 PEVILTATNSEHAIAAVRDGIADLGFIENPCPPTGLGSVVVARDELVVVV
Rv2282c|M.tuberculosis_H37Rv PEVILTATNSEHAIAAVRDGIADLGFIENPCPPTGLGSVVVARDELVVVV
MSMEG_4331|M.smegmatis_MC2_155 SFTFR-QFYPDALVEAVLDGTVHLGLRRGVVPTSAVATAVLGFDRVRLAL
TH_3504|M.thermoresistible__bu SFTLR-QLYPDALTDAVFDGTVQLGLRRGVVPTPELATAVIGYHRVRVAF
MAB_4795c|M.abscessus_ATCC_199 SVTAL-QVFPNALEPAVIGGSADIALRRGIATPKNLASRVIGYHALRVAV
Mflv_1356|M.gilvum_PYR-GCK ALDIHADLLTPDQCEGLRTGALDVGVLRPPAVGGDVATRTIAAEPLVLAV
Mvan_1027|M.vanbaalenii_PYR-1 KLDLR-EMVTAAQIEGLMTGELDLGMARPPLKRPGLVSRPLLHEQLLAAL
MLBr_02663|M.leprae_Br4923 KVQICSRLPVTELHRRLGDFELDAVIVHSAPDDTHAVDLVPLYHEHYVLV
: . . . . .
MMAR_3419|M.marinum_M PPGHKWTRRPSPVTARELAETPLVTREPRSGIRDSLTVALRQVLGEDMVQ
MUL_2698|M.ulcerans_Agy99 PPGHKWTRRPSPVTARELAEMPLVTREPRSGIRDSLTVALRQVLGEDMVQ
MAV_2151|M.avium_104 PPTHKWARRSRVVTARELAQTPLVAREPHSGIRDSLTVALRKVLGEDMQQ
Mb2303c|M.bovis_AF2122/97 PPGHKWARRSRVVSARELAQTPLVTREPNSGIRDSLTAALRDTLGEDMQQ
Rv2282c|M.tuberculosis_H37Rv PPGHKWARRSRVVSARELAQTPLVTREPNSGIRDSLTAALRDTLGEDMQQ
MSMEG_4331|M.smegmatis_MC2_155 PRDHRLAGKA-SVDISDVAGERIALWAP--PGASYYSDFLMGACRRAGFE
TH_3504|M.thermoresistible__bu VDSHPLAARE-SVDITELAREQVALWAP--PGTSYYSDFLMGACRRAGFE
MAB_4795c|M.abscessus_ATCC_199 PREHLLAERD-SVALRDLRNERIIVWAP--PGVSHYTDFILSTCRSAGFE
Mflv_1356|M.gilvum_PYR-GCK SADHRLAAEP-VVSLADLRSEPFIGYT---GQDSAVNDAVTRSCRAAGFV
Mvan_1027|M.vanbaalenii_PYR-1 PEGHPLADMTRELTLIDLDGQDFVMYSP--VQARYFNELLISTFTIAGTT
MLBr_02663|M.leprae_Br4923 SPADMLPPGASVLAWPEASQLPLALLTP----DMRDRQLIDRAFAGHAIT
. . : : . :
MMAR_3419|M.marinum_M ASPVLELSSAAAMRAAVLAGAGPAAMSRLAIADDLAVGRLRAISIP-GLD
MUL_2698|M.ulcerans_Agy99 ASPVLELSSAAAMRAAVLAGAGPAAMSRLAIADDLAVGRLRAISIP-GLD
MAV_2151|M.avium_104 AAPVLELTSAAAMRAAVLAGAGPAAMSRLAVADDLAVGRLHAVEIP-KLD
Mb2303c|M.bovis_AF2122/97 APPVLELSSAAAVRAAVLAGAGPAAMSRLAIADDLAFGRLLAVDIP-ALN
Rv2282c|M.tuberculosis_H37Rv APPVLELSSAAAVRAAVLAGAGPAAMSRLAIADDLAFGRLLAVDIP-ALN
MSMEG_4331|M.smegmatis_MC2_155 PDYVVSRVQGAATVAAPLTTDAIAFVT--APAGAAMDGRVVVVDL--QPE
TH_3504|M.thermoresistible__bu PDYVVSRVQGAATVAAPLTTGGIAFVT--AAAGPTMNGRVQVVDL--TPP
MAB_4795c|M.abscessus_ATCC_199 PAFVINHVQGTPPVTAVLDNDGVAFVT--APTGPCLAGQVVVIDI--VDP
Mflv_1356|M.gilvum_PYR-GCK PHREHSAPGTAVLLALVAADLGVSVVP--ASVRALPLHGVVFRDL--VDG
Mvan_1027|M.vanbaalenii_PYR-1 PRYVQYVTQVHTMLVLVRSGIGIALVP--ASAATLHPEGVVFRTIGAFRE
MLBr_02663|M.leprae_Br4923 ATPQVETDSVASLFAQVATGNWACIVPHTWLWTTPIGAEIRAVEMVDPVL
. . . :. : :
MMAR_3419|M.marinum_M LRRQLRAIWVGG-RVPPAGAIRELLSHITSGGE-----------------
MUL_2698|M.ulcerans_Agy99 LRRQLRAIWVGG-RVPPAGAIRELLSHITSGGE-----------------
MAV_2151|M.avium_104 LRRKFRAIWIGG-RTPPAGAIRDLLSHIIARTAASK--------------
Mb2303c|M.bovis_AF2122/97 LRRQLRAIWVGG-RTPPAGAIRDLLSHITSRST-----------------
Rv2282c|M.tuberculosis_H37Rv LRRQLRAIWVGG-RTPPAGAIRDLLSHITSRST-----------------
MSMEG_4331|M.smegmatis_MC2_155 LLVGAQALWQRHTHSAIRDMLLADGRRDSHDEIQACVRDEAADDAQRQVL
TH_3504|M.thermoresistible__bu LLVPVQALWQRHTLSAIRDRILEG--------------------------
MAB_4795c|M.abscessus_ATCC_199 PQAPIQAIWLPHTQSAIRDALTSG--------------------------
Mflv_1356|M.gilvum_PYR-GCK GTVDLALAWRDGVDNPVVDAVVAVLAGALTSLDHPALQEQS---------
Mvan_1027|M.vanbaalenii_PYR-1 RPVELDAVWRGDSTNP---ALLRVLKDVLPQQEWTT--------------
MLBr_02663|M.leprae_Br4923 KADVALATNSAGPGSPVARALVASAKQLALNEFFEAQLAGITRRR-----
. :
MMAR_3419|M.marinum_M ----------------
MUL_2698|M.ulcerans_Agy99 ----------------
MAV_2151|M.avium_104 ----------------
Mb2303c|M.bovis_AF2122/97 ----------------
Rv2282c|M.tuberculosis_H37Rv ----------------
MSMEG_4331|M.smegmatis_MC2_155 PPQGHDKGGRAGQRRG
TH_3504|M.thermoresistible__bu --LG------------
MAB_4795c|M.abscessus_ATCC_199 ----------------
Mflv_1356|M.gilvum_PYR-GCK ----------------
Mvan_1027|M.vanbaalenii_PYR-1 ----------------
MLBr_02663|M.leprae_Br4923 ----------------