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MPDLRRLRQFVAVADAGSVTAAAAALHLSQQALSSSIQQLEKQLGATLFHREGRRLRLTRAGEVLLVEGR PLLAAAHTIAARVEQTAHRADEAYVIGHTPALSGIEAYTHVERAITAFPDVSFTFRQFYPDALVEAVLDG TVHLGLRRGVVPTSAVATAVLGFDRVRLALPRDHRLAGKASVDISDVAGERIALWAPPGASYYSDFLMGA CRRAGFEPDYVVSRVQGAATVAAPLTTDAIAFVTAPAGAAMDGRVVVVDLQPELLVGAQALWQRHTHSAI RDMLLADGRRDSHDEIQACVRDEAADDAQRQVLPPQGHDKGGRAGQRRG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4331 | - | - | 100% (329) | putative transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_1909 | - | 4e-23 | 31.06% (322) | putative HTH-type transcriptional regulator YnfL |
| M. smegmatis MC2 155 | MSMEG_5654 | - | 8e-22 | 32.60% (227) | transcriptional regulator, LysR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2303c | - | 7e-11 | 27.81% (302) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1356 | - | 3e-20 | 30.00% (290) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2282c | - | 7e-11 | 27.81% (302) | LysR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02041 | oxyR | 5e-14 | 24.90% (249) | putative LysR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4795c | - | 1e-68 | 46.45% (282) | LysR family transcriptional regulator |
| M. marinum M | MMAR_3419 | - | 2e-12 | 28.00% (275) | LysR family transcriptional regulator |
| M. avium 104 | MAV_1538 | - | 2e-14 | 26.34% (243) | transcriptional regulator, LysR family protein |
| M. thermoresistible (build 8) | TH_3504 | - | 1e-107 | 69.96% (283) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_2698 | - | 1e-12 | 27.74% (274) | LysR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1027 | - | 4e-23 | 30.68% (251) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2303c|M.bovis_AF2122/97 --------------MPLSSR-----MPGLTCFEIFLAIAEAGSLGGAARE
Rv2282c|M.tuberculosis_H37Rv --------------MPLSSR-----MPGLTCFEIFLAIAEAGSLGGAARE
MMAR_3419|M.marinum_M --------------MPLSPR-----MPELGSFEIFLAIAQTGSLGAAARE
MUL_2698|M.ulcerans_Agy99 --------------MPLSPR-----MPELASFEIFLAIAQTGSLGAAARE
MSMEG_4331|M.smegmatis_MC2_155 --------------MP-----------DLRRLRQFVAVADAGSVTAAAAA
TH_3504|M.thermoresistible__bu --------------VPSPKI-------DLRRLAQFVAVAELGSFTRAAAT
MAB_4795c|M.abscessus_ATCC_199 --------------MPEHSAGIWDDPVDLRRLQQFLSVAEHSGFTRAAQQ
Mflv_1356|M.gilvum_PYR-GCK MVSAVTGRPTNDPPHTWRHRTIKEPPMELRHLRYFLAVAETCHFGQAAEQ
Mvan_1027|M.vanbaalenii_PYR-1 -------------------------MFSLARLSCFVAVAEELHFGRAAER
MAV_1538|M.avium_104 --------------------------MAVGDYEWFITLAELQHVTAAAEQ
MLBr_02041|M.leprae_Br4923 --------------MSDKSY-----QPTIAGLRAFVAVVEKGHFSAAASF
: *:::.: . **
Mb2303c|M.bovis_AF2122/97 LGLTQQAVSRRLASMEAQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLEV
Rv2282c|M.tuberculosis_H37Rv LGLTQQAVSRRLASMEAQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLEV
MMAR_3419|M.marinum_M LGLTQQAVSKRLAAMEAHTGVTLAVRTTRGSQLTPAGLIVSEWAARLLEV
MUL_2698|M.ulcerans_Agy99 LGLTQQAVSKRLAAMEAHTGVTLAVRTTRGSQLTPAGLIVSEWAARLLEV
MSMEG_4331|M.smegmatis_MC2_155 LHLSQQALSSSIQQLEKQLGATLFHREGRRLRLTRAGEVLLVEGRPLLAA
TH_3504|M.thermoresistible__bu LHLSQQALSSAVRALENDVGADLFTRDGRRISLTTAGRTLLAEGKPLLAA
MAB_4795c|M.abscessus_ATCC_199 LRLTQQAISQSVTNLEKQVGAKLFDRSGRHIALTPAGEVLRDGSVVLLAA
Mflv_1356|M.gilvum_PYR-GCK LHIAQPALSYAIRQLENSLDATLFTRTTRHVALTPAGEFLRVEATRILNG
Mvan_1027|M.vanbaalenii_PYR-1 LHMTQPPLSRQVQQLENELGVQLIDRTTRNVTLTPAGAAFLPDARRILQL
MAV_1538|M.avium_104 LHVAQPTLTRMLARLEQRLGVALFDRHGRRLSLNTYGRIFYEHARRAQLE
MLBr_02041|M.leprae_Br4923 LGVRQSTLSQALAALESGLGVQLIERSTRRVFVTTQGRHLLPRAQAAIEA
* : * .:: : :* .. * * * :. * . .
Mb2303c|M.bovis_AF2122/97 ADEIDAGLGSLRTEGRQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGTV
Rv2282c|M.tuberculosis_H37Rv ADEIDAGLGSLRTEGRQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGTV
MMAR_3419|M.marinum_M AQEIDAGLGSLRKEGRERIRVAASQTIAEQLMPHWLLALQDAAKRRGTTA
MUL_2698|M.ulcerans_Agy99 AQEIDAGLGSLRKEGRERIRVAASQTIAEQLMPHWLLALQDAAKRRGTTA
MSMEG_4331|M.smegmatis_MC2_155 AHTIAARVEQTAHRADEAYVIGHTPALSGIEAYTHVERAITAFP----DV
TH_3504|M.thermoresistible__bu ARTVAEHVRQTEAAAQAHYVIGHTPALSGAEAYALIEPAVTAYP----ST
MAB_4795c|M.abscessus_ATCC_199 AQTLVRQVQNTAAEQPRPFVVAHTPAITAEEVHQLLVPVRSALP----NV
Mflv_1356|M.gilvum_PYR-GCK VDAAQRGVRRIAAGRSGLLRLGLTGTAAFSHLPKIARIVRQELP----AV
Mvan_1027|M.vanbaalenii_PYR-1 AEGAAQTVKRIPAGDLGTVVVGFTAASAHAVLPRLLERARERLP----DV
MAV_1538|M.avium_104 LDSARRAIADLADPAVGEIRLAYLSSFGSTVVPRLIARFKESSP----RV
MLBr_02041|M.leprae_Br4923 MDAFTAAAAGESDPLRGGMRLGLIPTVAPYVLPTMLTGLTHRLP----TL
: :
Mb2303c|M.bovis_AF2122/97 PEVILTATNSEHAIAAVRDGIADLGFIENPCPPTGLGSVVVARDELVVVV
Rv2282c|M.tuberculosis_H37Rv PEVILTATNSEHAIAAVRDGIADLGFIENPCPPTGLGSVVVARDELVVVV
MMAR_3419|M.marinum_M PQVILTATNSDHAIAAVRDGTADLGFVENPGPPTGLGSRVVGHDDLVVVV
MUL_2698|M.ulcerans_Agy99 PQVILTATNSDHAIAAVRDGTADLGFVENPGPPTGLGSRVVGHDDLVVVV
MSMEG_4331|M.smegmatis_MC2_155 SFTFR-QFYPDALVEAVLDGTVHLGLRRGVVPTSAVATAVLGFDRVRLAL
TH_3504|M.thermoresistible__bu SFTLR-QLYPDALTDAVFDGTVQLGLRRGVVPTPELATAVIGYHRVRVAF
MAB_4795c|M.abscessus_ATCC_199 SVTAL-QVFPNALEPAVIGGSADIALRRGIATPKNLASRVIGYHALRVAV
Mflv_1356|M.gilvum_PYR-GCK ALDIHADLLTPDQCEGLRTGALDVGVLRPPAVGGDVATRTIAAEPLVLAV
Mvan_1027|M.vanbaalenii_PYR-1 KLDLR-EMVTAAQIEGLMTGELDLGMARPPLKRPGLVSRPLLHEQLLAAL
MAV_1538|M.avium_104 TFTLE-EGAAESIADRVRSGGVDIGVVSPRPVERTLAWRSLFRQRLGVAV
MLBr_02041|M.leprae_Br4923 TLRVV-EDQTEHLLTALREGALDAAMIALPVETAGIAEIPIYDEDFVLAL
. : * . .. : : . . ..
Mb2303c|M.bovis_AF2122/97 PPGHKWARRSRVVSARELAQTPLVTREPNSGIRDSLTAALRDTLGEDMQQ
Rv2282c|M.tuberculosis_H37Rv PPGHKWARRSRVVSARELAQTPLVTREPNSGIRDSLTAALRDTLGEDMQQ
MMAR_3419|M.marinum_M PPGHKWTRRPSPVTARELAETPLVTREPRSGIRDSLTVALRQVLGEDMVQ
MUL_2698|M.ulcerans_Agy99 PPGHKWTRRPSPVTARELAEMPLVTREPRSGIRDSLTVALRQVLGEDMVQ
MSMEG_4331|M.smegmatis_MC2_155 PRDHRLAGKA-SVDISDVAGERIALWAP--PGASYYSDFLMGACRRAGFE
TH_3504|M.thermoresistible__bu VDSHPLAARE-SVDITELAREQVALWAP--PGTSYYSDFLMGACRRAGFE
MAB_4795c|M.abscessus_ATCC_199 PREHLLAERD-SVALRDLRNERIIVWAP--PGVSHYTDFILSTCRSAGFE
Mflv_1356|M.gilvum_PYR-GCK SADHRLAAEP-VVSLADLRSEPFIGYT---GQDSAVNDAVTRSCRAAGFV
Mvan_1027|M.vanbaalenii_PYR-1 PEGHPLADMTRELTLIDLDGQDFVMYSP--VQARYFNELLISTFTIAGTT
MAV_1538|M.avium_104 PDGHRFARGA-AVSMVDLADEPFVTMHP----GFGMRRLLDELCAAAQFR
MLBr_02041|M.leprae_Br4923 PPGHPLSGKR-RVPTTALAQLPLLLLDEG----HCLRDQTLDICRKSGVQ
* : : : .
Mb2303c|M.bovis_AF2122/97 APPVLELSS-AAAVRAAVLAGAGPAAMSRLAIADDLAFGRLLAVDIP-AL
Rv2282c|M.tuberculosis_H37Rv APPVLELSS-AAAVRAAVLAGAGPAAMSRLAIADDLAFGRLLAVDIP-AL
MMAR_3419|M.marinum_M ASPVLELSS-AAAMRAAVLAGAGPAAMSRLAIADDLAVGRLRAISIP-GL
MUL_2698|M.ulcerans_Agy99 ASPVLELSS-AAAMRAAVLAGAGPAAMSRLAIADDLAVGRLRAISIP-GL
MSMEG_4331|M.smegmatis_MC2_155 PDYVVSRVQ-GAATVAAPLTTDAIAFVT--APAGAAMDGRVVVVDL--QP
TH_3504|M.thermoresistible__bu PDYVVSRVQ-GAATVAAPLTTGGIAFVT--AAAGPTMNGRVQVVDL--TP
MAB_4795c|M.abscessus_ATCC_199 PAFVINHVQ-GTPPVTAVLDNDGVAFVT--APTGPCLAGQVVVIDI--VD
Mflv_1356|M.gilvum_PYR-GCK PHREHSAPG-TAVLLALVAADLGVSVVP--ASVRALPLHGVVFRDL--VD
Mvan_1027|M.vanbaalenii_PYR-1 PRYVQYVTQ-VHTMLVLVRSGIGIALVP--ASAATLHPEGVVFRTIGAFR
MAV_1538|M.avium_104 PRVALQAPN-LTTAASLVAAGLGISLVP---IDGSSYPSGVSVKPLA-DA
MLBr_02041|M.leprae_Br4923 AELANTRAASLATAVQCVTGGLGVTLLPQSAAPVESVRSKLGLAQFAAPC
. . : :. : :
Mb2303c|M.bovis_AF2122/97 NLRRQLRAIWVGG-RTPPAGAIRDLLSHITSRST----------------
Rv2282c|M.tuberculosis_H37Rv NLRRQLRAIWVGG-RTPPAGAIRDLLSHITSRST----------------
MMAR_3419|M.marinum_M DLRRQLRAIWVGG-RVPPAGAIRELLSHITSGGE----------------
MUL_2698|M.ulcerans_Agy99 DLRRQLRAIWVGG-RVPPAGAIRELLSHITSGGE----------------
MSMEG_4331|M.smegmatis_MC2_155 ELLVGAQALWQRHTHSAIRDMLLADGRRDSHDEIQACVRDEAADDAQRQV
TH_3504|M.thermoresistible__bu PLLVPVQALWQRHTLSAIRDRILEG-------------------------
MAB_4795c|M.abscessus_ATCC_199 PPQAPIQAIWLPHTQSAIRDALTSG-------------------------
Mflv_1356|M.gilvum_PYR-GCK GGTVDLALAWRDGVDNPVVDAVVAVLAGALTSLDHPALQEQS--------
Mvan_1027|M.vanbaalenii_PYR-1 ERPVELDAVWRGDSTNP---ALLRVLKDVLPQQEWTT-------------
MAV_1538|M.avium_104 DAYRDVGMIWDSGRPLPRSARDFIAGAAAVGHGGW---------------
MLBr_02041|M.leprae_Br4923 PGRRIGLAFRSASGRSASYRQIAKIIGELISTEHHVRLVA----------
.
Mb2303c|M.bovis_AF2122/97 -----------------
Rv2282c|M.tuberculosis_H37Rv -----------------
MMAR_3419|M.marinum_M -----------------
MUL_2698|M.ulcerans_Agy99 -----------------
MSMEG_4331|M.smegmatis_MC2_155 LPPQGHDKGGRAGQRRG
TH_3504|M.thermoresistible__bu ---LG------------
MAB_4795c|M.abscessus_ATCC_199 -----------------
Mflv_1356|M.gilvum_PYR-GCK -----------------
Mvan_1027|M.vanbaalenii_PYR-1 -----------------
MAV_1538|M.avium_104 -----------------
MLBr_02041|M.leprae_Br4923 -----------------