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MTTLLRVTTSAPPTDAVLDAARTEFERHGMRRANMDAIARRAGVSRRTLYRRFPTKEALFEHLIEAESIT VFGQLAVAANGQDAPGAIVECFTLAMRLITESRLAGTIIENEPELVIGLNTPSGDKAIVRASALVASSLR HSGATMPDDAVLAVSEILVRLVGSLLTNRAGVLDITDTAAVRHYAQTYLARLVW
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4647 | - | - | 100% (194) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1024 | - | 3e-14 | 28.49% (179) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3273c | - | 4e-14 | 31.46% (178) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2274c | - | 2e-07 | 24.10% (166) | transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_5272 | - | 5e-26 | 37.50% (192) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2250c | - | 2e-07 | 24.10% (166) | transcriptional regulator |
| M. leprae Br4923 | MLBr_00316 | - | 4e-05 | 51.16% (43) | putative TetR/AcrR-family transcriptional regulator |
| M. marinum M | MMAR_0287 | - | 2e-32 | 42.37% (177) | transcriptional regulatory protein |
| M. avium 104 | MAV_5227 | - | 5e-29 | 40.68% (177) | TetR-family protein transcriptional regulator, putative |
| M. smegmatis MC2 155 | MSMEG_0962 | - | 2e-17 | 39.50% (119) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_2255 | - | 3e-17 | 31.55% (187) | TetR-family protein transcriptional regulator |
| M. ulcerans Agy99 | MUL_4837 | - | 6e-32 | 41.81% (177) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0969 | - | 1e-26 | 39.69% (194) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2274c|M.bovis_AF2122/97 ---------------MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAE
Rv2250c|M.tuberculosis_H37Rv ---------------MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAE
Mflv_5272|M.gilvum_PYR-GCK -------------MRRARNTDSPTEQESAILKAAAEEVALVGVGRLSMDV
Mvan_0969|M.vanbaalenii_PYR-1 -------------MRRTRTRNTPTEQESAILKAAAEEVALVGVGRLSMDV
MAB_4647|M.abscessus_ATCC_1997 -------------MTTLLRVTTSAPPTDAVLDAARTEFERHGMRRANMDA
MMAR_0287|M.marinum_M ------MQSRMGTETSTDGVESITDLDRTILDTARAVFETYGVRRANIED
MUL_4837|M.ulcerans_Agy99 ----------MGTETSTDGVESITDLDRTILDTAHAVFETYGVRRANIED
MAV_5227|M.avium_104 ----------MQSHRADAAAGERTDLDRLILDTARGVFETYGVRRANIDD
MSMEG_0962|M.smegmatis_MC2_155 ------------------MP-GPDAASRAILDAALVEFERYGFRRVALDD
TH_2255|M.thermoresistible__bu ------------------MPERPDPARQAILDAAVVEFEQHGFRKVALED
MLBr_00316|M.leprae_Br4923 MSVPRSGLSVQMAQPARPLRADAARNRARILGVAYEAFATEGLS-VPIDE
:* .* . *. :
Mb2274c|M.bovis_AF2122/97 IARRAGVSRPTVYRRWPDTRSIMASMLTSHIAAVLREVPLDGDD----RE
Rv2250c|M.tuberculosis_H37Rv IARRAGVSRPTVYRRWPDTRSIMASMLTSHIADVLREVPLDGDD----RE
Mflv_5272|M.gilvum_PYR-GCK VARQAGVSRSTLYRRFPSRDALITELGRQTFEFAMARLQTVAIDDGPQ-Q
Mvan_0969|M.vanbaalenii_PYR-1 VARQAGVSRSTLYRRFPTRDALITELGRQTFDFAMARLQTVAIDSGPQ-Q
MAB_4647|M.abscessus_ATCC_1997 IARRAGVSRRTLYRRFPTKEALFEHLIEAESITVFGQLAVAANGQDAP-G
MMAR_0287|M.marinum_M VATRAGVSRSTIYRRFPTKDELFERVVRREAELFFAALNQATNGHNPR-E
MUL_4837|M.ulcerans_Agy99 VATRAGVSRSTIYRRFPTKDELFERVVRREAELFFAALNQATNGHNPR-E
MAV_5227|M.avium_104 VAARAGVSRSTIYRRFPTKKNLFGQVVRREAELFFSTLDQATAGCDPQ-Q
MSMEG_0962|M.smegmatis_MC2_155 VARRAGVSRTTIYRRFANRDDLVGAVIERENVSLFADIAAELKDAKPQSN
TH_2255|M.thermoresistible__bu VARRAGVSRTTIYRRFTNRDELVAAVVDRENAALFADIAAELKHSGPQGD
MLBr_00316|M.leprae_Br4923 IARRAGVGAGTVYRHFPTKEALCAAVIGDRMPHLVDDGYVLLKSAGPG-E
:* :***. *:**::. : : .
Mb2274c|M.bovis_AF2122/97 ALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTSQQVLIEGLAAR
Rv2250c|M.tuberculosis_H37Rv ALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTSQQVLIEGLAAR
Mflv_5272|M.gilvum_PYR-GCK AAVAAFREGVRLLTGEPVMRRFLQLDGEFTATTEMVAEARLFLVSAATAM
Mvan_0969|M.vanbaalenii_PYR-1 AAVAAFTEGVRLLTGEPVMRRFLQLDREFTATTEMVEEARLFLVSAATAM
MAB_4647|M.abscessus_ATCC_1997 AIVECFTLAMRLITESRLAGTIIENEPELVIGLNTPSGDK-AIVRASALV
MMAR_0287|M.marinum_M AVIEAFTLGVRLIQDSPLYSRIAESEPELFGMFSR--SHVFPIGQFADGI
MUL_4837|M.ulcerans_Agy99 AVIEAFTLGVRLIRDSPLYSRIAESEPELFGMFSR--SHVFPIGQFADGI
MAV_5227|M.avium_104 AVIEAFALGVRLVKNSALYSRIAESEPELFGLFSR--SQVFPIRQFADGI
MSMEG_0962|M.smegmatis_MC2_155 IYVEAFTLSILRFRRHRVLNQMMKDEPALVLELAHRHYGAAIERMAAALR
TH_2255|M.thermoresistible__bu YYVEAFTLAILKFRRHRVLHRMITDEPGFILHLAQQHWGAAVERMAEALR
MLBr_00316|M.leprae_Br4923 ALFTYLRSLVLHWGATDRGLVDALAGAGGIDILGVAPDAEDAFLTILSDL
. :
Mb2274c|M.bovis_AF2122/97 LTVAQRSGS-VRSGDARRLATMVLLIAQSTIQSA--DIVDSILDS--AAL
Rv2250c|M.tuberculosis_H37Rv LTVAQRSGS-VRSGDARRLATMVLLIAQSTIQSA--DIVDSILDS--AAL
Mflv_5272|M.gilvum_PYR-GCK AKALRAAGATMPDSELLAVAEVHIRLAASLVQVN-TDVLDVTDDE---AV
Mvan_0969|M.vanbaalenii_PYR-1 AKALRAAGAGMPDDELLAVAEIHIRLAASLVQVS-SDVLDVGDDE---AV
MAB_4647|M.abscessus_ATCC_1997 ASSLRHSGATMPDDAVLAVSEILVRLVGSLLTNR-AGVLDITDTA---AV
MMAR_0287|M.marinum_M AHTLRRCGADAPDADLANIADILLRVAVGIIMFP-TERLDTSDDA---AV
MUL_4837|M.ulcerans_Agy99 AHTLRRCGADAPDADLANIADILLRVAVGIIMFP-TERLDTSDDA---AV
MAV_5227|M.avium_104 AHTLRRCGAEQAEPDLDNIADILLRVALGIIVFP-TDRLDTADPA---AV
MSMEG_0962|M.smegmatis_MC2_155 VIFPEGFADRIGEAAVNDLADTILRYALMALLIPSVEPLETADDIRSFAT
TH_2255|M.thermoresistible__bu VIFPAGFAERIGEAAVIEFADTILRYAAMALLLPSVQPLDTADDIRAFAT
MLBr_00316|M.leprae_Br4923 LYAAQYAGTARTDVGVREVKSILVGCQAMEAYNS--------------AL
. . . : *
Mb2274c|M.bovis_AF2122/97 ATELTHALNGYLC---
Rv2250c|M.tuberculosis_H37Rv ATELTHALNGYLC---
Mflv_5272|M.gilvum_PYR-GCK ARYARTYLAPLVR---
Mvan_0969|M.vanbaalenii_PYR-1 ARYARTYLAPLVH---
MAB_4647|M.abscessus_ATCC_1997 RHYAQTYLARLVW---
MMAR_0287|M.marinum_M REYAARYLIPIITL--
MUL_4837|M.ulcerans_Agy99 REYAARYLIPIITL--
MAV_5227|M.avium_104 RDYAARYLVPIIGR--
MSMEG_0962|M.smegmatis_MC2_155 RHFLPSLPVSLRVVPA
TH_2255|M.thermoresistible__bu RHFLPSLPAALHTGSA
MLBr_00316|M.leprae_Br4923 AERVTDVVVDGLRAAR