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DDENDTTARKRLPRGQGWQLRQQIIDTAMDLILSSGEARAPSARELTRALGITAPSLYRHFSSTDELADA LCARYFEQLGEALQRATVNVSTALERLHALGLAYVRHAAEHPLWYRFATANPPRLGAESDEILSSSAFLH LRDIVQELVDEERFPRGNTLGSALQLWATTHGVASLLVTRPYLPWGEQESFASRTLRAAYLGQVMTAGPE SADGDGK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4510c | - | - | 100% (218) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1288 | - | 3e-55 | 52.50% (200) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4352c | - | 1e-06 | 27.34% (139) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3233 | - | 1e-05 | 29.73% (111) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2132 | - | 2e-46 | 44.12% (204) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3208 | - | 1e-05 | 29.73% (111) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 2e-06 | 29.46% (112) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_4304 | - | 3e-42 | 42.11% (209) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4155 | - | 1e-06 | 31.53% (111) | TetR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_5177 | - | 3e-46 | 43.43% (198) | regulatory protein, TetR |
| M. thermoresistible (build 8) | TH_4347 | - | 4e-08 | 24.85% (169) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_0990 | - | 1e-42 | 42.11% (209) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4572 | - | 6e-47 | 45.45% (198) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2132|M.gilvum_PYR-GCK ---------------MSEHGV------RRRRAPRGAGEHLRDEILDAATE
Mvan_4572|M.vanbaalenii_PYR-1 ------------MADVSAPRQ------RRHRAPRGAGEQLRAEILDAATD
MSMEG_5177|M.smegmatis_MC2_155 -----------MSTPNSHPGANSPCPIKRRRARRGSGELLREEILDATTD
MMAR_4304|M.marinum_M ---------------MSMGRL------RRARAPRGSGDLLRHEILDAATE
MUL_0990|M.ulcerans_Agy99 --------------------M------RRARAPRGSGDLLRHEILDAATE
MAB_4510c|M.abscessus_ATCC_199 ------------MDDENDTTA-------RKRLPRGQGWQLRQQIIDTAMD
Mb3233|M.bovis_AF2122/97 MSDLAKTAQRRALRSSGSARPDEDVPAPNRRGNRLPRDERRGQLLVVASD
Rv3208|M.tuberculosis_H37Rv MSDLAKTAQRRALRSSGSARPDEDVPAPNRRGNRLPRDERRGQLLVVASD
MAV_4155|M.avium_104 MSELAKMPARRAVKSADRGRPTDGAAASNRRGNRLPRDERRGQLLVVASD
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
TH_4347|M.thermoresistible__bu ----------------------------------VTADDIREKLVDAGVR
* ::: .
Mflv_2132|M.gilvum_PYR-GCK LLLESGDEKAVSVRSVAERVGVTPPSLYLHFADKNALLDAVCGRYFEKLD
Mvan_4572|M.vanbaalenii_PYR-1 LLLETGDEKAVSIRSVAQRVGVTPPSIYLHFVDKTALLDAVCGRYFEKLD
MSMEG_5177|M.smegmatis_MC2_155 LLLETGHAKDVSIRAVAKRVGVTPPSIYLHFADKDALLDAVCARYFEKLD
MMAR_4304|M.marinum_M LLLQTRQARAVSIRSVAERVGVTPPSIYLHFQDKDALLDAVCARYLARLD
MUL_0990|M.ulcerans_Agy99 LLLQTRQARAVSIRSVAERVGVTSPSIYLHFQDKDALLDAVCARYLARLD
MAB_4510c|M.abscessus_ATCC_199 LILSSGEARAPSARELTRALGITAPSLYRHFSSTDELADALCARYFEQLG
Mb3233|M.bovis_AF2122/97 VFVDRG-YHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLHRHVENLV
Rv3208|M.tuberculosis_H37Rv VFVDRG-YHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLHRHVENLV
MAV_4155|M.avium_104 VFVDRG-YHAAGMDEIADRAGVSKPVLYQHFTSKLELYLAVLARHVENLV
MLBr_00815|M.leprae_Br4923 VFVDHG-YHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLV
TH_4347|M.thermoresistible__bu LLERDG-VQALSARNLAAEAGTSTMAVYTRFGGMPGVLEAVAGEIFARFA
:: : . :: * : :* :* . : *: . . .:
Mflv_2132|M.gilvum_PYR-GCK EQMQAVAAACPSTIEVLRAQGLAYVRFALQTPELYRIATMGHGNP---GS
Mvan_4572|M.vanbaalenii_PYR-1 EEMQEVAGAAATALDVLRAQGMAYVRFALKNPVLYRIAMMGPGSP---GS
MSMEG_5177|M.smegmatis_MC2_155 QQMQRVAAGQPSTIDVLRAQGLAYVEFATHTPELYRLATMAEGRP---GS
MMAR_4304|M.marinum_M EEMERAAMGHTCVVEVLRAQGLAYVRFALQTPELYRLATMGEWRS---GS
MUL_0990|M.ulcerans_Agy99 EEMERAAMGHTCVVEVLRAQGLAYVRFALQTPELYRLATMGEWRS---GS
MAB_4510c|M.abscessus_ATCC_199 EALQRATVNVSTALERLHALGLAYVRHAAEHPLWYRFATANPPRL---GA
Mb3233|M.bovis_AF2122/97 SGVHQALSTTTDNRQRLHVAVQAFFDFIEHDSQGYRLIFENDFVT---EP
Rv3208|M.tuberculosis_H37Rv SGVHQALSTTTDNRQRLHVAVQAFFDFIEHDSQGYRLIFENDFVT---EP
MAV_4155|M.avium_104 SGVQQALSTTKDNRRRLHAAVQAFFDFIEHDSQGYRLIFENDYVT---EP
MLBr_00815|M.leprae_Br4923 SSVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDNIT---EP
TH_4347|M.thermoresistible__bu DALTQIPQTG-DPVADFLLMGAAYREYALTHPQRYLLMFGTATPASIAGS
. : : *: . * : .
Mflv_2132|M.gilvum_PYR-GCK GVDLTLN---------SAAFVHMRASVEALIAEGVYPPGDPTVFALELWT
Mvan_4572|M.vanbaalenii_PYR-1 DVDVALN---------SSAFGHLLMSVQALIAEGVYPQADPTMLALELWT
MSMEG_5177|M.smegmatis_MC2_155 DVDITLN---------SSAFQHMRATIEKLMDEGIYPPGDATTWALELWT
MMAR_4304|M.marinum_M NVDSALD---------SSAFRHMCASVQAMMDEGIYRADDPTTIALELWT
MUL_0990|M.ulcerans_Agy99 NVDSALD---------SSAFRHMCASVQAMMDEGIYRADDPTTIALELWT
MAB_4510c|M.abscessus_ATCC_199 ESDEILS---------SSAFLHLRDIVQELVDEERFPRGNTLGSALQLWA
Mb3233|M.bovis_AF2122/97 EVAAQVR---------VATESCIDAVFALISADSGLDPHRARMIAVGLVG
Rv3208|M.tuberculosis_H37Rv EVAAQVR---------VATESCIDAVFALISADSGLDPHRARMIAVGLVG
MAV_4155|M.avium_104 EVAAQVR---------VATESCIDAVYALISEDSGLDPHRARMIAVGLVG
MLBr_00815|M.leprae_Br4923 RVAAQVR---------VATESCIDAVFALISADSRLDPHRARMVAVGLVG
TH_4347|M.thermoresistible__bu RADLTATGEVSDRTEWAASFEALRTMVRRMIAAGRIRDDGEAAIAGRLWS
:: : : * *
Mflv_2132|M.gilvum_PYR-GCK CAHGIAAQLISRPYLPWGDVEQFADRVLRAVCIGHMVSVAIGPDENAMDT
Mvan_4572|M.vanbaalenii_PYR-1 AVHGIAAMLISRPYLPWGGAEEFADRLMRAVCCGQALSVAIRPDESPREI
MSMEG_5177|M.smegmatis_MC2_155 AAHGVAAMLIAKPYLPWGDTHEFADRVLRAVCSGHIVSGIIGNDVTPSEA
MMAR_4304|M.marinum_M AAHGVAALLIAKPHLPFGDVAAFADRVLGAVLCGHMVAGLVGPQATSRDL
MUL_0990|M.ulcerans_Agy99 AAHGVAALLIAKPHLPFGDVAAFADRVLGAVLCGHMVAGLVGPQATSRDL
MAB_4510c|M.abscessus_ATCC_199 TTHGVASLLVTRPYLPWGEQESFASRTLRAAYLGQVMT--AGPESADGDG
Mb3233|M.bovis_AF2122/97 MSVDCARYWLDA-DKPISKSDAVEG-TVQFAWGGLSHVPLTRS-------
Rv3208|M.tuberculosis_H37Rv MSVDCARYWLDA-DKPISKSDAVEG-TVQFAWGGLSHVPLTRS-------
MAV_4155|M.avium_104 ISVDCARYWLDS-DRPISKADAVEG-TVAFAWGGLSHVPLTRS-------
MLBr_00815|M.leprae_Br4923 ISVDCARYWLDT-NRPISKSDAVEG-TVQFAWGGLSHVPLTRL-------
TH_4347|M.thermoresistible__bu LIHGEVMLELAGFFGAEGHG-------LTKILTPMTVDMLVGLGDDRARV
. . : . . :
Mflv_2132|M.gilvum_PYR-GCK VNWLKEVVDERRRR-
Mvan_4572|M.vanbaalenii_PYR-1 MTWLKEVVDERQRG-
MSMEG_5177|M.smegmatis_MC2_155 VARLKGLADAPN---
MMAR_4304|M.marinum_M MDWVVQHRPSEESRV
MUL_0990|M.ulcerans_Agy99 MDWVVQHRPSEESRV
MAB_4510c|M.abscessus_ATCC_199 K--------------
Mb3233|M.bovis_AF2122/97 ---------------
Rv3208|M.tuberculosis_H37Rv ---------------
MAV_4155|M.avium_104 ---------------
MLBr_00815|M.leprae_Br4923 ---------------
TH_4347|M.thermoresistible__bu EASLTTAAEAHGR--