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VTRRQRASRGSGDRLRDEIIDAAIALVLETKELRAPSIREVARKIGVTPPSIYLHFADKDELMDAVCGQY FQRLNDKMVEAARGDITALERLHAQGMAYVRFAIATPLMYRLATVTQPEGELDETMASAAFAHLHNGVKE LVTEGLYPEGDTVAMALQLWVAAHGVASMLVTKPHLPWGDPEEFASEVLRAACLGQAVSDIDLTEVLPRQ K
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1288 | - | - | 100% (211) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4510c | - | 3e-55 | 52.50% (200) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0499 | - | 5e-10 | 32.14% (140) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0672c | - | 1e-06 | 28.32% (173) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2132 | - | 1e-60 | 53.27% (199) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0653c | - | 1e-06 | 28.32% (173) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 1e-07 | 29.75% (121) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_4304 | - | 5e-55 | 52.24% (201) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0603 | - | 6e-08 | 26.77% (127) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5177 | - | 5e-61 | 52.86% (210) | regulatory protein, TetR |
| M. thermoresistible (build 8) | TH_4347 | - | 1e-10 | 27.06% (170) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_0990 | - | 3e-54 | 51.74% (201) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4572 | - | 1e-60 | 51.90% (210) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0672c|M.bovis_AF2122/97 ---------------------------------MTSQTGVRDELLHAGVR
Rv0653c|M.tuberculosis_H37Rv ---------------------------------MTSQTGVRDELLHAGVR
TH_4347|M.thermoresistible__bu ----------------------------------VTADDIREKLVDAGVR
Mflv_2132|M.gilvum_PYR-GCK ---------------MSEHGV------RRRRAPRGAGEHLRDEILDAATE
Mvan_4572|M.vanbaalenii_PYR-1 ------------MADVSAPRQ------RRHRAPRGAGEQLRAEILDAATD
MSMEG_5177|M.smegmatis_MC2_155 -----------MSTPNSHPGANSPCPIKRRRARRGSGELLREEILDATTD
MMAR_4304|M.marinum_M ---------------MSMGRL------RRARAPRGSGDLLRHEILDAATE
MUL_0990|M.ulcerans_Agy99 --------------------M------RRARAPRGSGDLLRHEILDAATE
MAB_1288|M.abscessus_ATCC_1997 ---------------MT----------RRQRASRGSGDRLRDEIIDAAIA
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
MAV_0603|M.avium_104 --------------------------------MTGPANSRRDELLELAAA
. * :::
Mb0672c|M.bovis_AF2122/97 LLDDHG-PDALQTRKVAAAAGTSTMAVYTHFGGMRGLIAAIAEEGLRQFD
Rv0653c|M.tuberculosis_H37Rv LLDDHG-PDALQTRKVAAAAGTSTMAVYTHFGGMRGLIAAIAEEGLRQFD
TH_4347|M.thermoresistible__bu LLERDG-VQALSARNLAAEAGTSTMAVYTRFGGMPGVLEAVAGEIFARFA
Mflv_2132|M.gilvum_PYR-GCK LLLESGDEKAVSVRSVAERVGVTPPSLYLHFADKNALLDAVCGRYFEKLD
Mvan_4572|M.vanbaalenii_PYR-1 LLLETGDEKAVSIRSVAQRVGVTPPSIYLHFVDKTALLDAVCGRYFEKLD
MSMEG_5177|M.smegmatis_MC2_155 LLLETGHAKDVSIRAVAKRVGVTPPSIYLHFADKDALLDAVCARYFEKLD
MMAR_4304|M.marinum_M LLLQTRQARAVSIRSVAERVGVTPPSIYLHFQDKDALLDAVCARYLARLD
MUL_0990|M.ulcerans_Agy99 LLLQTRQARAVSIRSVAERVGVTSPSIYLHFQDKDALLDAVCARYLARLD
MAB_1288|M.abscessus_ATCC_1997 LVLETKELRAPSIREVARKIGVTPPSIYLHFADKDELMDAVCGQYFQRLN
MLBr_00815|M.leprae_Br4923 VFVDHG-YHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLV
MAV_0603|M.avium_104 MFAERG-LRATTVRDIADSAGILSGSLYHHFSSKEEMVDEVLRSFLDWLF
:. :* * :* :* . : : : :
Mb0672c|M.bovis_AF2122/97 VALT-VPQTADPVADLL-AIGTAYRRYAIERPHMYRLMFGSTSAHGIN-V
Rv0653c|M.tuberculosis_H37Rv VALT-VPQTADPVADLL-AIGTAYRRYAIERPHMYRLMFGSTSAHGIN-V
TH_4347|M.thermoresistible__bu DALTQIPQTGDPVADFL-LMGAAYREYALTHPQRYLLMFGTATPASIAGS
Mflv_2132|M.gilvum_PYR-GCK EQMQAVAAACPSTIEVLRAQGLAYVRFALQTPELYRIATMGHGNPGSG--
Mvan_4572|M.vanbaalenii_PYR-1 EEMQEVAGAAATALDVLRAQGMAYVRFALKNPVLYRIAMMGPGSPGSD--
MSMEG_5177|M.smegmatis_MC2_155 QQMQRVAAGQPSTIDVLRAQGLAYVEFATHTPELYRLATMAEGRPGSD--
MMAR_4304|M.marinum_M EEMERAAMGHTCVVEVLRAQGLAYVRFALQTPELYRLATMGEWRSGSN--
MUL_0990|M.ulcerans_Agy99 EEMERAAMGHTCVVEVLRAQGLAYVRFALQTPELYRLATMGEWRSGSN--
MAB_1288|M.abscessus_ATCC_1997 DKMVEAARGDITALERLHAQGMAYVRFAIATPLMYRLATVTQ--PEGE--
MLBr_00815|M.leprae_Br4923 SSVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDNITEPR--
MAV_0603|M.avium_104 ARYREIIDSESNPLERLKGLFMASFEAIEHRHAQVVIYQDEAKRLLSQ--
: * * :
Mb0672c|M.bovis_AF2122/97 PARDVLTLKVAEIEHQHPSFAHVVRAVHRCLLAGRFATALGADDDTAIVA
Rv0653c|M.tuberculosis_H37Rv PARDVLTLKVAEIEHQHPSFAHVVRAVHRCLLAGRFATALGADDDTAIVA
TH_4347|M.thermoresistible__bu RADLTATGEVSDRTEWAASFEALRTMVRRMIAAGRIR-------DDGEAA
Mflv_2132|M.gilvum_PYR-GCK ----------VDLTLNSAAFVHMRASVEALIAEGVYP-------PGDPTV
Mvan_4572|M.vanbaalenii_PYR-1 ----------VDVALNSSAFGHLLMSVQALIAEGVYP-------QADPTM
MSMEG_5177|M.smegmatis_MC2_155 ----------VDITLNSSAFQHMRATIEKLMDEGIYP-------PGDATT
MMAR_4304|M.marinum_M ----------VDSALDSSAFRHMCASVQAMMDEGIYR-------ADDPTT
MUL_0990|M.ulcerans_Agy99 ----------VDSALDSSAFRHMCASVQAMMDEGIYR-------ADDPTT
MAB_1288|M.abscessus_ATCC_1997 ----------LDETMASAAFAHLHNGVKELVTEGLYP-------EGDTVA
MLBr_00815|M.leprae_Br4923 ----------VAAQVRVATESCIDAVFALISADSRLD-------PHRARM
MAV_0603|M.avium_104 ------PRFSYIEDMNRQQRKMWLEVLNQGVDEGYFR-------PDLDVD
. .
Mb0672c|M.bovis_AF2122/97 TAAQFWSQIHGFVMLELAG---FYGDRGAAVEPVLAAMTVNLLVALGDSP
Rv0653c|M.tuberculosis_H37Rv TAAQFWSQIHGFVMLELAG---FYGDRGAAVEPVLAAMTVNLLVALGDSP
TH_4347|M.thermoresistible__bu IAGRLWSLIHGEVMLELAG---FFGAEGHGLTKILTPMTVDMLVGLGDDR
Mflv_2132|M.gilvum_PYR-GCK FALELWTCAHGIAAQLISRPYLPWGDVEQFADRVLRAVCIGHMVSVAIGP
Mvan_4572|M.vanbaalenii_PYR-1 LALELWTAVHGIAAMLISRPYLPWGGAEEFADRLMRAVCCGQALSVAIRP
MSMEG_5177|M.smegmatis_MC2_155 WALELWTAAHGVAAMLIAKPYLPWGDTHEFADRVLRAVCSGHIVSGIIGN
MMAR_4304|M.marinum_M IALELWTAAHGVAALLIAKPHLPFGDVAAFADRVLGAVLCGHMVAGLVGP
MUL_0990|M.ulcerans_Agy99 IALELWTAAHGVAALLIAKPHLPFGDVAAFADRVLGAVLCGHMVAGLVGP
MAB_1288|M.abscessus_ATCC_1997 MALQLWVAAHGVASMLVTKPHLPWGDPEEFASEVLRAACLGQAVS-----
MLBr_00815|M.leprae_Br4923 VAVGLVGISVDCARYWLDTN---------------RPISKSDAVEGTVQF
MAV_0603|M.avium_104 LVYRFIRDTTWVSVRWYQPG---------------GPLTAEQVGQQYLAI
. : .
Mb0672c|M.bovis_AF2122/97 ERAQCSLRAEQTQKNTLGRAT-
Rv0653c|M.tuberculosis_H37Rv ERAQCSLRAEQTQKNTLGRAT-
TH_4347|M.thermoresistible__bu ARVEASL---TTAAEAHGR---
Mflv_2132|M.gilvum_PYR-GCK DENAMDTVNWLKEVVDERRRR-
Mvan_4572|M.vanbaalenii_PYR-1 DESPREIMTWLKEVVDERQRG-
MSMEG_5177|M.smegmatis_MC2_155 DVTPSEAVARLKGLADAPN---
MMAR_4304|M.marinum_M QATSRDLMDWVVQHRPSEESRV
MUL_0990|M.ulcerans_Agy99 QATSRDLMDWVVQHRPSEESRV
MAB_1288|M.abscessus_ATCC_1997 DIDLTEVLPRQK----------
MLBr_00815|M.leprae_Br4923 AWGGLSHVPLTRL---------
MAV_0603|M.avium_104 VLGGITVDAKKD----------