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MSELAKMPARRAVKSADRGRPTDGAAASNRRGNRLPRDERRGQLLVVASDVFVDRGYHAAGMDEIADRAG VSKPVLYQHFTSKLELYLAVLARHVENLVSGVQQALSTTKDNRRRLHAAVQAFFDFIEHDSQGYRLIFEN DYVTEPEVAAQVRVATESCIDAVYALISEDSGLDPHRARMIAVGLVGISVDCARYWLDSDRPISKADAVE GTVAFAWGGLSHVPLTRS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4155 | - | - | 100% (228) | TetR-family protein transcriptional regulator |
| M. avium 104 | MAV_1159 | - | 5e-22 | 31.79% (195) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_4919 | - | 1e-13 | 28.06% (196) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3233 | - | 1e-112 | 86.84% (228) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4672 | - | 1e-99 | 79.13% (230) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3208 | - | 1e-112 | 86.84% (228) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 1e-104 | 81.50% (227) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3527 | - | 4e-85 | 68.89% (225) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1350 | - | 1e-107 | 85.09% (228) | TetR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_1935 | - | 3e-98 | 79.39% (228) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_0452 | - | 1e-102 | 79.39% (228) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_2529 | - | 1e-107 | 85.09% (228) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1795 | - | 2e-99 | 78.26% (230) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4672|M.gilvum_PYR-GCK MSELAKTAPRRGGQPANGTGSS----GAARRGNRLPRDERRGQLLAAASE
Mvan_1795|M.vanbaalenii_PYR-1 MSEVARTAQRRGGQPANGASPS----GAARRGNRMPRDERRGQLLIAASE
TH_0452|M.thermoresistible__bu MSEVADTTARQEITPTNGGTTSGAAAGANRRGNRLPRDERRNQLLIAASE
MSMEG_1935|M.smegmatis_MC2_155 MSDLANTAERRGEKRPAG---------GNRRGNRLPRDERRGQLLIAASE
Mb3233|M.bovis_AF2122/97 MSDLAKTAQRRALRSSGSARPDEDVPAPNRRGNRLPRDERRGQLLVVASD
Rv3208|M.tuberculosis_H37Rv MSDLAKTAQRRALRSSGSARPDEDVPAPNRRGNRLPRDERRGQLLVVASD
MMAR_1350|M.marinum_M MSDLAKAAQHRAVRSADRVR-STEGATPKARGNRLPRDERRGQLLIVASD
MUL_2529|M.ulcerans_Agy99 MSDLAKAAQHRAVRSADRVR-STEGATPKARGNRLPRDERRGQLLIVASD
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
MAV_4155|M.avium_104 MSELAKMPARRAVKSADRGRPTDGAAASNRRGNRLPRDERRGQLLVVASD
MAB_3527|M.abscessus_ATCC_1997 MRDLAKLAGRRGTVNSTVAT-QDSTQGNTRRGGRLPRDERRGQLVGSASE
* ::* . :: *..*:.**:**.**: **:
Mflv_4672|M.gilvum_PYR-GCK VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKVELYLAVLQRHVDNLVS
Mvan_1795|M.vanbaalenii_PYR-1 VFVDRGYHAAGMDEIADRAGVSKPVLYQHFTSKVELYLAVLQRHVDNLVS
TH_0452|M.thermoresistible__bu VFVDRGYHAAGMDEIAERAGVSKPVLYQHFSSKLELYLAVLQRHVDNLVS
MSMEG_1935|M.smegmatis_MC2_155 VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLQRHVDNLVS
Mb3233|M.bovis_AF2122/97 VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLHRHVENLVS
Rv3208|M.tuberculosis_H37Rv VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLHRHVENLVS
MMAR_1350|M.marinum_M VFVDRGYHAAGMDEIAERAGVSKPVLYQHFSSKLELYLAVLNRHVDKLVA
MUL_2529|M.ulcerans_Agy99 VFVDRGYHAAGMDEIAERAGVSKPVLYQHFSSKLELYLAVLNRHVDKLVA
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
MAV_4155|M.avium_104 VFVDRGYHAAGMDEIADRAGVSKPVLYQHFTSKLELYLAVLARHVENLVS
MAB_3527|M.abscessus_ATCC_1997 IFVDRGYHAAGMDEIADRAGVSKPVLYQHFPSKLELYLAVLHKHADNLVS
:***:***********:*************.**:******* :* ::**:
Mflv_4672|M.gilvum_PYR-GCK GVRQALRTTTDNRQRVRAAVQAFFDFIEHDSQGYRLIFENDYVTEPQVAA
Mvan_1795|M.vanbaalenii_PYR-1 GVRQALRTTTDNRQRVRAAVQAFFDFIEHDGQGYRLIFENDYVTEPQVAA
TH_0452|M.thermoresistible__bu GVRQALRTTTDNRQRLRAAVQAFFDFIEHDGQGYRLIFENDYVTEPQVAA
MSMEG_1935|M.smegmatis_MC2_155 GVRQALRTTTDNRQRLRAAVEAFFDFIEHDSQGYRLIFENDYVTEPQVAA
Mb3233|M.bovis_AF2122/97 GVHQALSTTTDNRQRLHVAVQAFFDFIEHDSQGYRLIFENDFVTEPEVAA
Rv3208|M.tuberculosis_H37Rv GVHQALSTTTDNRQRLHVAVQAFFDFIEHDSQGYRLIFENDFVTEPEVAA
MMAR_1350|M.marinum_M GVQQALRTTTDNRGRLYAAVQAFFDFIEHDSQGYRLIFENDYVTEPEVAA
MUL_2529|M.ulcerans_Agy99 GVQQALRTTTDNRGRLYAAVQAFFDFIEHDSQGYRLIFENDYVTEPEVAA
MLBr_00815|M.leprae_Br4923 SVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDNITEPRVAA
MAV_4155|M.avium_104 GVQQALSTTKDNRRRLHAAVQAFFDFIEHDSQGYRLIFENDYVTEPEVAA
MAB_3527|M.abscessus_ATCC_1997 SVRQALRTTTDNRQRLRAAVMAFFDFVEHDSQGYRLIFENDLVGVPQVSE
.*:*** **.:** *: .** *****:***.********** : *.*:
Mflv_4672|M.gilvum_PYR-GCK QVKVATESCTDAVFDLISHDSGLEPHRARMIAVGLVSISVDSARYWLNNE
Mvan_1795|M.vanbaalenii_PYR-1 QVKVATESCTDAVFDLISHDSGLEPHRARMIAVGLVSISVDSARYWLNND
TH_0452|M.thermoresistible__bu QVKVATEACTDAVFDLISQDSGLEAHRARMIAVGLVAISVDCARYWLHAD
MSMEG_1935|M.smegmatis_MC2_155 QVKVATEACTDAVFDLISRDSGLEAHRARMIAVGLVAISVDSARYWLNND
Mb3233|M.bovis_AF2122/97 QVRVATESCIDAVFALISADSGLDPHRARMIAVGLVGMSVDCARYWLDAD
Rv3208|M.tuberculosis_H37Rv QVRVATESCIDAVFALISADSGLDPHRARMIAVGLVGMSVDCARYWLDAD
MMAR_1350|M.marinum_M QVRVATESCIDAVFALISADSGLDPHRARMIAVALVSMSVDCARYWLDSD
MUL_2529|M.ulcerans_Agy99 QVRVATESCIDAVFALISADSGLDPHRARMIAVALVSMSVDCARYWLDSD
MLBr_00815|M.leprae_Br4923 QVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGISVDCARYWLDTN
MAV_4155|M.avium_104 QVRVATESCIDAVYALISEDSGLDPHRARMIAVGLVGISVDCARYWLDSD
MAB_3527|M.abscessus_ATCC_1997 RVEGAISACTDAVFDLVSHDSGLDPHHARMVAVGLVGISQVSARYWLDNE
:*. * .:* ***: *:* ** *:.*:***:**.**.:* .*****. :
Mflv_4672|M.gilvum_PYR-GCK RPIDKDDAVEGTVQFIWGGLSHVPLTRS-
Mvan_1795|M.vanbaalenii_PYR-1 RPIDKDDAVEGTVQFIWGGLSHVPMTRS-
TH_0452|M.thermoresistible__bu RPISKEDAVEGTVQFAWGGLSHVPLTRS-
MSMEG_1935|M.smegmatis_MC2_155 RPIDKDSAVEGTVQFAWGGLSHVPLTRS-
Mb3233|M.bovis_AF2122/97 KPISKSDAVEGTVQFAWGGLSHVPLTRS-
Rv3208|M.tuberculosis_H37Rv KPISKSDAVEGTVQFAWGGLSHVPLTRS-
MMAR_1350|M.marinum_M RPISKSDAIEGTVQFAWGGLSHVPLARS-
MUL_2529|M.ulcerans_Agy99 RPISKSDAIEGTVQFAWGGLSHVPLARS-
MLBr_00815|M.leprae_Br4923 RPISKSDAVEGTVQFAWGGLSHVPLTRL-
MAV_4155|M.avium_104 RPISKADAVEGTVAFAWGGLSHVPLTRS-
MAB_3527|M.abscessus_ATCC_1997 KPISKDDAVNATVGFAWGGLSHVPLQPHG
:**.* .*::.** * ********: