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MSESKPGRRERYAALTRSAIVEAARMLFVERGFDDTSVDDIAEAAQVSKGAIYHHFKDKQEIFIDVYRDA TKGVIENVVKVLIDVPAGSWNRIEAAASAVIKGYTDNREPRVLVRQVMGVLGAERTQALEGELALPLIRT LLTEAEENGELRDLSIEKASQLIFRVLCESSLLIANSADYAEAAQEVETVMLCMFAGLRKPPAATRGRRK S
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2290 | - | - | 100% (211) | transcriptional regulator TetR |
| M. abscessus ATCC 19977 | MAB_4648 | - | 1e-20 | 30.26% (195) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4352c | - | 6e-15 | 29.44% (197) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0080 | - | 5e-15 | 26.90% (197) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_2460 | - | 2e-11 | 32.94% (170) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0078 | - | 4e-15 | 26.90% (197) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_02677 | - | 1e-09 | 24.46% (184) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_0224 | - | 1e-14 | 26.90% (197) | transcriptional regulatory protein |
| M. avium 104 | MAV_5253 | - | 5e-18 | 28.93% (197) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6807 | - | 2e-10 | 33.55% (155) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3094 | - | 2e-18 | 27.32% (194) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_4890 | - | 6e-15 | 27.41% (197) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4194 | - | 3e-10 | 39.19% (74) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0224|M.marinum_M MEIKRRTQEER---SAATREALITAARKLWGSRGYAEVGTPEIAAEAGV-
MUL_4890|M.ulcerans_Agy99 MESKRRTQEER---SAATREALITAARKLWGSRGYAEVGTPEIAAEAGV-
Mb0080|M.bovis_AF2122/97 MEIKRRTQEER---SAATREALITGARKLWGLRGYAEVGTPEIATEAGV-
Rv0078|M.tuberculosis_H37Rv MEIKRRTQEER---SAATREALITGARKLWGLRGYAEVGTPEIATEAGV-
MAV_5253|M.avium_104 MESKRRTQEER---SAATRDALIAAARKLWGLRGYTEVGTPEIAAAAGV-
MLBr_02677|M.leprae_Br4923 MESQRRTQEER---STATRDALTLARHRLWRLRGYAEVGTPEIAKEADT-
TH_3094|M.thermoresistible__bu MSKRGGRVEDRRARGDQTRRDLIDAGRALFVDPGYFHTSVGDLVERSGVG
Mflv_2460|M.gilvum_PYR-GCK -MVERWTRERR---LEHTRSVLLDAAEEVFAEKGFTPATLDDIARAAGY-
Mvan_4194|M.vanbaalenii_PYR-1 -MAERWTRERR---LEHTRSVLLDAAEEVFAEKGFTPATLDDIARTAGY-
MSMEG_6807|M.smegmatis_MC2_155 -MVERWTRERR---LEHTRSLLLDAAENVFSEKGFTAATLDDIAFAAGY-
MAB_2290|M.abscessus_ATCC_1997 MSESKPGRRER--YAALTRSAIVEAARMLFVERGFDDTSVDDIAEAAQV-
. * ** : . . :: *: . ::. :
MMAR_0224|M.marinum_M TRGAMYHQFADKAALFGEVVEAVEQDVMTRMATSVAASGAATPADAIRAA
MUL_4890|M.ulcerans_Agy99 TRGAMYHQFADKAALFGEVVEAVEQDVMTRMATSVTTSGAATPADAIRAA
Mb0080|M.bovis_AF2122/97 TRGAMYHQFADKAALFRDVVEVVEQDVMARMATLVAASGAATPADAIRAA
Rv0078|M.tuberculosis_H37Rv TRGAMYHQFADKAALFRDVVEVVEQDVMARMATLVAASGAATPADAIRAA
MAV_5253|M.avium_104 TRGAMYHQFADKAALFRAVVEAVEQDVMARMAVVVAESGASTPTDAIRAA
MLBr_02677|M.leprae_Br4923 TRGAVYHQFTDKAALFRDVVETVEQDAMAQIASVVASSGAKTPVDAIRAK
TH_3094|M.thermoresistible__bu TRGAFYHHFPDKAALFRAVFEDVEQDLTLRSIASPPEG--SDSWERLTRG
Mflv_2460|M.gilvum_PYR-GCK TKGAIYKHFDTKEELFLAVSDRYWRRYFDNFAEVMSSAS-RVGADELDEI
Mvan_4194|M.vanbaalenii_PYR-1 TKGAIYKHFATKEDLFLAVSDRYWRRYFDNFAEVMASAS-RVGAHELDEI
MSMEG_6807|M.smegmatis_MC2_155 TKGAIYKHFATKEDLFLAVSDRYWRRYFDNFAEVMASAA-SVGARELDEI
MAB_2290|M.abscessus_ATCC_1997 SKGAIYHHFKDKQEIFIDVYRDATKGVIENVVKVLIDVP-AGSWNRIEAA
::**.*::* * :* * : . :
MMAR_0224|M.marinum_M VDAWLEVSGD--PEVRQLILLDAPAVLGWAGFRDVAQRYSLGMTEQ----
MUL_4890|M.ulcerans_Agy99 VDAWLEVSGD--PEVRQLILLDAPAVLGWAGFCDVAQRYSLGMTEQ----
Mb0080|M.bovis_AF2122/97 VDAWLEVSGD--PEVRQLVLLDAPVVLGWAGFRDVAQRYSLGMTEQ----
Rv0078|M.tuberculosis_H37Rv VDAWLEVSGD--PEVRQLILLDAPVVLGWAGFRDVAQRYSLGMTEQ----
MAV_5253|M.avium_104 VDAWLEVSAD--PEVRQLILLDAPSVLGWAEFRDVAQRYSLGMTEQ----
MLBr_02677|M.leprae_Br4923 VDAWLEGLAD--PQVRQLILLYAPSVLGWAAFRDVAQHYSLGMTEQQ---
TH_3094|M.thermoresistible__bu LHGFLDAAAE--PEVQRIILIDGPVVLGWQTLRSIEERSSLAMIQQ----
Mflv_2460|M.gilvum_PYR-GCK AERWRQLSIDRGAEHAALGLEFTLYLLRNPEARERVEAKRAEVVDQLAEF
Mvan_4194|M.vanbaalenii_PYR-1 AERWRQLSIDRGADHAALGLEFTLYLLRNPDARERVAAKRAEVVDQLAKF
MSMEG_6807|M.smegmatis_MC2_155 AKRWRQLSVDRGAEQAALGLEFTLYLKRNPEARDRVAAKRSEVVAQLTAF
MAB_2290|M.abscessus_ATCC_1997 ASAVIKGYTD--NREPRVLVRQVMGVLGAERTQALEGELALPLIRT----
. : : : : :
MMAR_0224|M.marinum_M LITEAIRAGQLDRHPVRPLAHVLIGALDEAAMFIATAD-----DPKR---
MUL_4890|M.ulcerans_Agy99 LITEAIRAGQLDRHPVRPLAHVLIGALDEAAMFIATAD-----DPKR---
Mb0080|M.bovis_AF2122/97 LITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATAD-----DPKR---
Rv0078|M.tuberculosis_H37Rv LITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATAD-----DPKR---
MAV_5253|M.avium_104 LLTEAIRAGELAEQPVRPLAHVLIGALDEAAMVIATAD-----DPDR---
MLBr_02677|M.leprae_Br4923 LLSEASRARQLA----QPLDHVLIGKLYESAMAIRRHHRLPEASPARNQT
TH_3094|M.thermoresistible__bu ILRRAIADGSIEEQPVTALTHMLVSAVEEASLLIAHST-----DPER---
Mflv_2460|M.gilvum_PYR-GCK IVEGMSQLGATLLIEPSTFARALVATSDSVVLGSQLDA------------
Mvan_4194|M.vanbaalenii_PYR-1 INEGMTRLGASLLISPLTFAQALVATSDSVVLASQLDD------------
MSMEG_6807|M.smegmatis_MC2_155 IVASIEKLGATLLISPETFAHALVATSDSVVLSSELDN------------
MAB_2290|M.abscessus_ATCC_1997 LLTEAEENGELRDLSIEKASQLIFRVLCESSLLIANSAD-----------
: : :. . :
MMAR_0224|M.marinum_M ----------AR------------RESRQVLRRLIDGMLND---------
MUL_4890|M.ulcerans_Agy99 ----------AR------------RESRQVLRRLIDGMLND---------
Mb0080|M.bovis_AF2122/97 ----------AR------------RETRQVLRRLIDGMLNG---------
Rv0078|M.tuberculosis_H37Rv ----------AR------------RETRQVLRRLIDGMLNG---------
MAV_5253|M.avium_104 ----------AR------------RETRQVLQRLVDGMFDAR--------
MLBr_02677|M.leprae_Br4923 GAAPTHREHVARPSCEALTRHIRHRSTRTRSHRGKRGELLPRAATSSLL-
TH_3094|M.thermoresistible__bu -----AR-----------------SDAEAVLDTLLNALTRRRSRSR----
Mflv_2460|M.gilvum_PYR-GCK ------------------------VDLYRPMVEMYVSVIKLPD-------
Mvan_4194|M.vanbaalenii_PYR-1 ------------------------IDLYRPVVEMYTSVIKLPD-------
MSMEG_6807|M.smegmatis_MC2_155 ------------------------VDLYRPMVEMYASMIKLPT-------
MAB_2290|M.abscessus_ATCC_1997 -------------------YAEAAQEVETVMLCMFAGLRKPPAATRGRRK
. .
MMAR_0224|M.marinum_M -
MUL_4890|M.ulcerans_Agy99 -
Mb0080|M.bovis_AF2122/97 -
Rv0078|M.tuberculosis_H37Rv -
MAV_5253|M.avium_104 -
MLBr_02677|M.leprae_Br4923 -
TH_3094|M.thermoresistible__bu -
Mflv_2460|M.gilvum_PYR-GCK -
Mvan_4194|M.vanbaalenii_PYR-1 -
MSMEG_6807|M.smegmatis_MC2_155 -
MAB_2290|M.abscessus_ATCC_1997 S