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MEIKRRTQEERSAATREALITAARKLWGSRGYAEVGTPEIAAEAGVTRGAMYHQFADKAALFGEVVEAVE QDVMTRMATSVAASGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPAVLGWAGFRDVAQRYSLGMTEQ LITEAIRAGQLDRHPVRPLAHVLIGALDEAAMFIATADDPKRARRESRQVLRRLIDGMLND
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0224 | - | - | 100% (201) | transcriptional regulatory protein |
| M. marinum M | MMAR_0684 | - | 8e-09 | 35.71% (98) | putative regulatory protein |
| M. marinum M | MMAR_1239 | - | 3e-08 | 37.76% (98) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0080 | - | 1e-100 | 93.00% (200) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_4802 | - | 4e-09 | 39.53% (86) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0078 | - | 1e-101 | 93.50% (200) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_02677 | - | 2e-60 | 69.71% (175) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4352c | - | 1e-19 | 28.21% (195) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5253 | - | 4e-92 | 85.50% (200) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1565 | - | 6e-10 | 27.84% (176) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3094 | - | 4e-33 | 38.42% (190) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_4890 | - | 1e-107 | 98.01% (201) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_2880 | - | 9e-11 | 33.62% (116) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0224|M.marinum_M MEIKRRTQEER-------SAATREALITAARKLWGSRGYAEVGTPEIAAE
MUL_4890|M.ulcerans_Agy99 MESKRRTQEER-------SAATREALITAARKLWGSRGYAEVGTPEIAAE
Mb0080|M.bovis_AF2122/97 MEIKRRTQEER-------SAATREALITGARKLWGLRGYAEVGTPEIATE
Rv0078|M.tuberculosis_H37Rv MEIKRRTQEER-------SAATREALITGARKLWGLRGYAEVGTPEIATE
MAV_5253|M.avium_104 MESKRRTQEER-------SAATRDALIAAARKLWGLRGYTEVGTPEIAAA
MLBr_02677|M.leprae_Br4923 MESQRRTQEER-------STATRDALTLARHRLWRLRGYAEVGTPEIAKE
TH_3094|M.thermoresistible__bu MSKRGGRVEDRR----ARGDQTRRDLIDAGRALFVDPGYFHTSVGDLVER
MAB_4352c|M.abscessus_ATCC_199 MVPLRQAQALA----------TRQRLVDVATELFALHGFTSVTTTSLSEA
MSMEG_1565|M.smegmatis_MC2_155 MRQTRAARSGPGRPAGTDSVDTRQRVIDAACRCFAQFGYGPATNNQIAEM
Mvan_2880|M.vanbaalenii_PYR-1 MSRIEAD--------------TREHLLTVAERLFLDAGYENVSVRAVCAT
Mflv_4802|M.gilvum_PYR-GCK MAEARRRLSPD---------DRRNELLALGAEVFGQRPYDEVRIDEIAER
* * : : : . :
MMAR_0224|M.marinum_M AGV-TRGAMYHQFADKAALFGEVVEAVEQDVMTRMATSVAASGAATPADA
MUL_4890|M.ulcerans_Agy99 AGV-TRGAMYHQFADKAALFGEVVEAVEQDVMTRMATSVTTSGAATPADA
Mb0080|M.bovis_AF2122/97 AGV-TRGAMYHQFADKAALFRDVVEVVEQDVMARMATLVAASGAATPADA
Rv0078|M.tuberculosis_H37Rv AGV-TRGAMYHQFADKAALFRDVVEVVEQDVMARMATLVAASGAATPADA
MAV_5253|M.avium_104 AGV-TRGAMYHQFADKAALFRAVVEAVEQDVMARMAVVVAESGASTPTDA
MLBr_02677|M.leprae_Br4923 ADT-TRGAVYHQFTDKAALFRDVVETVEQDAMAQIASVVASSGAKTPVDA
TH_3094|M.thermoresistible__bu SGVGTRGAFYHHFPDKAALFRAVFEDVEQDLTLRSIASPPEG--SDSWER
MAB_4352c|M.abscessus_ATCC_199 SGM-TRGALYHHFANMTEVMEAVFERAEGFLVAEVNHS--LTSIESPAER
MSMEG_1565|M.smegmatis_MC2_155 AGV-TAGSVYYHFGTKNKLFEAVCDDVYGKILTRVMLAVSGS--HSVVGL
Mvan_2880|M.vanbaalenii_PYR-1 AGV-NPAAVHYHFGSKVGLVSALLEARLGPLWEDALTEAAGEGPAGISDA
Mflv_4802|M.gilvum_PYR-GCK AGV-SRALMYHYFPDKRAFFAAVVRAESERLFDATNTPAQPG--QTLFTQ
:. . . .:: * .. :
MMAR_0224|M.marinum_M IRAAVDAWLEVSG-DPEVRQLILLDAPAVLGWAGFRDVAQRYSLGMTEQ-
MUL_4890|M.ulcerans_Agy99 IRAAVDAWLEVSG-DPEVRQLILLDAPAVLGWAGFCDVAQRYSLGMTEQ-
Mb0080|M.bovis_AF2122/97 IRAAVDAWLEVSG-DPEVRQLVLLDAPVVLGWAGFRDVAQRYSLGMTEQ-
Rv0078|M.tuberculosis_H37Rv IRAAVDAWLEVSG-DPEVRQLILLDAPVVLGWAGFRDVAQRYSLGMTEQ-
MAV_5253|M.avium_104 IRAAVDAWLEVSA-DPEVRQLILLDAPSVLGWAEFRDVAQRYSLGMTEQ-
MLBr_02677|M.leprae_Br4923 IRAKVDAWLEGLA-DPQVRQLILLYAPSVLGWAAFRDVAQHYSLGMTEQQ
TH_3094|M.thermoresistible__bu LTRGLHGFLDAAA-EPEVQRIILIDGPVVLGWQTLRSIEERSSLAMIQQ-
MAB_4352c|M.abscessus_ATCC_199 FLAIGSAVLDVLAREPIVQRIVFVEAPMALGWSRWRALDGGRSLGLIQDI
MSMEG_1565|M.smegmatis_MC2_155 LRAVLTESMRINHESPELAGFVATAPIDARRHRELAESFATQGARMADAL
Mvan_2880|M.vanbaalenii_PYR-1 VRIVVEPLVELAG-DPAGRLYLHLLSRLLLARVELSWTRRWFAVAPWVAL
Mflv_4802|M.gilvum_PYR-GCK VRAGVLAYLRYDELHPHGAWAAYMG--MSRSDPVLRGIDDHDNDRQANR-
. : *
MMAR_0224|M.marinum_M --LITEAIRAGQLDRHPVRPLAHVLIGALDEAAMFIATAD-----DPKR-
MUL_4890|M.ulcerans_Agy99 --LITEAIRAGQLDRHPVRPLAHVLIGALDEAAMFIATAD-----DPKR-
Mb0080|M.bovis_AF2122/97 --LITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATAD-----DPKR-
Rv0078|M.tuberculosis_H37Rv --LITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATAD-----DPKR-
MAV_5253|M.avium_104 --LLTEAIRAGELAEQPVRPLAHVLIGALDEAAMVIATAD-----DPDR-
MLBr_02677|M.leprae_Br4923 --LLSEASRARQLA----QPLDHVLIGKLYESAMAIRRHHRLPEASPARN
TH_3094|M.thermoresistible__bu --ILRRAIADGSIEEQPVTALTHMLVSAVEEASLLIAHST-----DPER-
MAB_4352c|M.abscessus_ATCC_199 --LEELYRRGELVEAVDPQMAAQLILGAINESGMYAAAAP------SERS
MSMEG_1565|M.smegmatis_MC2_155 TDAVRSGQDAGDIAADLDPVRVARLISAVVDGFAHAAVSA-----DPDE-
Mvan_2880|M.vanbaalenii_PYR-1 --LRRHLPELSERDAEARWMLAFELIFTQFGDPLAGDRRLS-----ARR-
Mflv_4802|M.gilvum_PYR-GCK -IIDRVTAGVEPLDAKVERDLRAAVYGWLAFTFEMCRQRLMDASLDADYL
: .
MMAR_0224|M.marinum_M ------------AR------------RESRQVLRRLIDGMLND-------
MUL_4890|M.ulcerans_Agy99 ------------AR------------RESRQVLRRLIDGMLND-------
Mb0080|M.bovis_AF2122/97 ------------AR------------RETRQVLRRLIDGMLNG-------
Rv0078|M.tuberculosis_H37Rv ------------AR------------RETRQVLRRLIDGMLNG-------
MAV_5253|M.avium_104 ------------AR------------RETRQVLQRLVDGMFDAR------
MLBr_02677|M.leprae_Br4923 QTGAAPTHREHVARPSCEALTRHIRHRSTRTRSHRGKRGELLPRAATSSL
TH_3094|M.thermoresistible__bu -------AR-----------------SDAEAVLDTLLNALTRRRSRSR--
MAB_4352c|M.abscessus_ATCC_199 --------------------------SRAAEQLTLLCRGLLSPRSG----
MSMEG_1565|M.smegmatis_MC2_155 -----------------------------MDNMNELFQSLLLDTT-----
Mvan_2880|M.vanbaalenii_PYR-1 -----------------------------VQTLQAFVAAGLSAPVESR--
Mflv_4802|M.gilvum_PYR-GCK G------------------DLCAHALMDALARVPGIPADLAEAVAPDRR-
MMAR_0224|M.marinum_M -
MUL_4890|M.ulcerans_Agy99 -
Mb0080|M.bovis_AF2122/97 -
Rv0078|M.tuberculosis_H37Rv -
MAV_5253|M.avium_104 -
MLBr_02677|M.leprae_Br4923 L
TH_3094|M.thermoresistible__bu -
MAB_4352c|M.abscessus_ATCC_199 -
MSMEG_1565|M.smegmatis_MC2_155 -
Mvan_2880|M.vanbaalenii_PYR-1 -
Mflv_4802|M.gilvum_PYR-GCK -