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MNFRRARSEEQREIRRQAILETASSMLSDMPVSQISLNELSRRTGLAKSAMIRYFESREAVLLELLDGAL RDWVTEIVTELSRDTYDGSAQQRADHLAALLSRSLREHAVLCDLMTAQPGVLEYNVSPETLLCFRRSAHT TIARYTDAIRSFIPELGDDSQSVSLSTVVTSAALWMYAQPSASAIAAAEAEPALADISLNFDTDLETMLS RLIIGALVKRSS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4312 | - | - | 100% (222) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1136 | - | 1e-17 | 26.48% (219) | transcriptional regulator TetR |
| M. abscessus ATCC 19977 | MAB_2299c | - | 2e-17 | 26.58% (222) | transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0460 | - | 4e-18 | 27.73% (220) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_4816 | - | 1e-07 | 32.00% (100) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0452 | - | 5e-18 | 27.73% (220) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_00064 | - | 7e-08 | 45.28% (53) | putative transcriptional regulator |
| M. marinum M | MMAR_0773 | - | 3e-19 | 29.02% (224) | putative regulatory protein |
| M. avium 104 | MAV_4698 | - | 8e-14 | 27.86% (201) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1741 | - | 5e-07 | 36.51% (63) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_2336 | - | 2e-07 | 28.97% (107) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4787 | - | 4e-08 | 35.63% (87) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1626 | - | 1e-08 | 37.00% (100) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0460|M.bovis_AF2122/97 ----------------------------MRYPLAVAQLGFQRARTEENKR
Rv0452|M.tuberculosis_H37Rv ----------------------------MRYPLAVAQLGFQRARTEENKR
MMAR_0773|M.marinum_M -----------MRKGTVPGRHYPRKSRSVRYPLAVAQLTFRRARTEENKR
MAV_4698|M.avium_104 --------------------------------------------------
Mflv_4816|M.gilvum_PYR-GCK MGSRQEISAACGRFHTVNSRTPSSRRGHSSRSRSKDGNSRETLSREERKE
Mvan_1626|M.vanbaalenii_PYR-1 ----------------MNSRTPSSRSGRS-RSREKD-----TLSREERKE
MUL_4787|M.ulcerans_Agy99 ----------------MNERTPSSRPHRS--SRSRD-----SPSREERKE
MSMEG_1741|M.smegmatis_MC2_155 ----------------MNRRTPSTRTRRSETSRSRD-----TLTREERKE
MAB_4312|M.abscessus_ATCC_1997 -------------------------------------MNFRRARSEEQRE
MLBr_00064|M.leprae_Br4923 ---------------------------MINSTAGQTSQSRSRRSTRPSGD
TH_2336|M.thermoresistible__bu --------------------------VSGVGKPISREAALLTSRASAGTG
Mb0460|M.bovis_AF2122/97 QRAAALVEAARSLALETGVASVTLTAVAGRAGIHYSAVRRYFTSHKEVLL
Rv0452|M.tuberculosis_H37Rv QRAAALVEAARSLALETGVASVTLTAVAGRAGIHYSAVRRYFTSHKEVLL
MMAR_0773|M.marinum_M QRAAALVEAARSMASETGVASVTLTAVASRAGIHYSAVRRYFTSHKEVLL
MAV_4698|M.avium_104 ------MEAARSLALETGVASVTLTAVARRAGIHYSAVRRYFTSHKEVLL
Mflv_4816|M.gilvum_PYR-GCK ATRRAIVDAALHLLAERGFSALSLREVTREAGIVPAAFYRHFDSMEALGL
Mvan_1626|M.vanbaalenii_PYR-1 ATRRAIVAAALSLLAERSFSGLSLREVTREAGIVPAAFYRHFESMEALGL
MUL_4787|M.ulcerans_Agy99 ATRRAIIAAALKLVHDRSFSALSLREVTREAGIVPAAFYRHFESMEALGL
MSMEG_1741|M.smegmatis_MC2_155 ATRRALIAAALKLLKDHSFSALSLREVTREAGIVPAAFYRHFDSMDALGL
MAB_4312|M.abscessus_ATCC_1997 IRRQAILETASSMLSDMPVSQISLNELSRRTGLAKSAMIRYFESREAVLL
MLBr_00064|M.leprae_Br4923 DRELAILATAEQLLEDRPLTEISVDYLAKSAGISRPTFYFYFASKEAVLL
TH_2336|M.thermoresistible__bu PTRQRLIEVAIELFKQHSVAGTSLQMISDALGLTKSAIYHHFRTRDELLT
: .* : : .: :: :: *: .:. :* : . :
Mb0460|M.bovis_AF2122/97 HLAAEGWARWSGTVCEQL-----GEPGPMSAPRVAEALANGLAADPLFCD
Rv0452|M.tuberculosis_H37Rv HLAAEGWARWSGTVCEQL-----GEPGPMSAPRVAEALANGLAADPLFCD
MMAR_0773|M.marinum_M HLAAEGWQRWSNTVCGEL-----SQPGPMTESRVAAALADGLAADPLFCD
MAV_4698|M.avium_104 HLSAEGWVRWSNTVSDKL-----AQPGAATPSRIAETLADALADDPLFCD
Mflv_4816|M.gilvum_PYR-GCK VLIDESFRSLREMLRG-------ARAGKLDPNRVIESSVDILIDG-VQQR
Mvan_1626|M.vanbaalenii_PYR-1 VLIDESFRALREMLRG-------ARAGKLDPNRVIESSVDILIDS-VQQR
MUL_4787|M.ulcerans_Agy99 VLIDESFRTLRDTLRG-------ARAGRLDPNRVIESSVEILIGS-VAER
MSMEG_1741|M.smegmatis_MC2_155 VLIDESFRSLRDMLRG-------ARAGKLDPHHVIESSAEILVSS-FNER
MAB_4312|M.abscessus_ATCC_1997 ELLDGALRDWVTEIVTELSRDTYDGSAQQRADHLAALLSRSLREHAVLCD
MLBr_00064|M.leprae_Br4923 TLLDRVFNKANAALETLIK-----NRDNKRGNKWRTGINVFFETFGSHKA
TH_2336|M.thermoresistible__bu AVMEPLISEVAEIVSAAEAR----RGARTRADHFLRGYAALAAAHREVIS
: : :
Mb0460|M.bovis_AF2122/97 LLANLHLHLEQEVDVDRVIEVKRTSIAAVIALVDAIESALPALGRSGAFD
Rv0452|M.tuberculosis_H37Rv LLANLHLHLEQEVDVDRVIEVKRTSIAAVIALVDAIESALPALGRSGAFD
MMAR_0773|M.marinum_M LLANLHLHLEHEVEVDRVVEVKRTSTAAVIALADAIENALPALGRAGAFD
MAV_4698|M.avium_104 LLANLHLHLEHEVDAERVVEVKRISTAATLSLADSIQRALPELGRSGSLD
Mflv_4816|M.gilvum_PYR-GCK REHWRFIGRERSTGVTVLRYAIRTEIRLITSELAIDLARFPALNTWSSED
Mvan_1626|M.vanbaalenii_PYR-1 REHWRFIGRERSTGVTVLRYAIRTEIRLITSELAIDLARFPNLNTWSSED
MUL_4787|M.ulcerans_Agy99 REHWRFIVRERSTGLSVLRYAIRTDIRLITSELATDLARFPGLNEWSTED
MSMEG_1741|M.smegmatis_MC2_155 REHWRFIARERSGGASALRYAIRTEIRLITSELAIDLARFPALKDWSSED
MAB_4312|M.abscessus_ATCC_1997 LMTAQPGVLEYNVSPETLLCFRRSAHTTIARYTDAIRSFIPELGD-DSQS
MLBr_00064|M.leprae_Br4923 VTCAGQVTRDNTEVRKLWSTFMQKWISYTAAVIDAERKRGVAPDTLPATE
TH_2336|M.thermoresistible__bu LLTG-------DPGVVALLRTRPDWAEVVQRQMALLGDVQPGPGGRVKAA
Mb0460|M.bovis_AF2122/97 ILLAAYSLAATLWQIANPPERLTDAYAEEPELLPPEWNLDFAAALTRLLT
Rv0452|M.tuberculosis_H37Rv ILLAAYSLAATLWQIANPPERLTDAYAEEPELLPPEWNLDFAAALTRLLT
MMAR_0773|M.marinum_M VLLAAYSLGATLWQIANPPQRLTDVYAEEPDVLPPEWNLDFAAALTRLLT
MAV_4698|M.avium_104 ILLAAYSLAATLWQVANPPERLTDAYAEEPEVVPPEWNLDFASALTRLLT
Mflv_4816|M.gilvum_PYR-GCK LNILASVFVNSMIAIAEQLEDVTDTASVDEIRR-------TAVKQLRMIT
Mvan_1626|M.vanbaalenii_PYR-1 LNILASVFVNSMIVIAESLEDATDPASIAEIRR-------IAIKQLRMIT
MUL_4787|M.ulcerans_Agy99 LNILATMFVNAMIVTAEAIEDAQSSEALEEIRR-------IAVKQLRMVA
MSMEG_1741|M.smegmatis_MC2_155 LNILANLFVNSMISLAEALEDAADAESIEAIHR-------TAVKQMRMIA
MAB_4312|M.abscessus_ATCC_1997 VSLSTVVTSAALWMYAQPSASAIAAAEAEPALADISLN--FDTDLETMLS
MLBr_00064|M.leprae_Br4923 LATALNLMNERALFASFTAEQPHVPESR------------VLDTLVHIWV
TH_2336|M.thermoresistible__bu VVMAGIAAAAGVDYGDLDEAALRDELLAAG------------RRTLGLRA
: :
Mb0460|M.bovis_AF2122/97 ATLLGLLAGSPCECRSPTR
Rv0452|M.tuberculosis_H37Rv ATLLGLLAGSPCECRSPTR
MMAR_0773|M.marinum_M ATCCGLTAKSS--------
MAV_4698|M.avium_104 ATCIGLIPQSA--------
Mflv_4816|M.gilvum_PYR-GCK VGVAGWRSG----------
Mvan_1626|M.vanbaalenii_PYR-1 VGVAGWRSS----------
MUL_4787|M.ulcerans_Agy99 IGVAGWKSRP---------
MSMEG_1741|M.smegmatis_MC2_155 VGVNGWRSTD---------
MAB_4312|M.abscessus_ATCC_1997 RLIIGALVKRSS-------
MLBr_00064|M.leprae_Br4923 SSIYNEIR-----------
TH_2336|M.thermoresistible__bu PHARG--------------
.