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M. avium 104 MAV_4698 (-)

EAARSLALETGVASVTLTAVARRAGIHYSAVRRYFTSHKEVLLHLSAEGWVRWSNTVSDKLAQPGAATPS
RIAETLADALADDPLFCDLLANLHLHLEHEVDAERVVEVKRISTAATLSLADSIQRALPELGRSGSLDIL
LAAYSLAATLWQVANPPERLTDAYAEEPEVVPPEWNLDFASALTRLLTATCIGLIPQSA*

Operon Prediction Model: Genebank

Paralogs

species	id	gene	e-value	identity (len)	annotation
M. avium 104	MAV_4698	-	-	100% (200)	transcriptional regulator, TetR family protein
M. avium 104	MAV_0721	-	2e-06	25.14% (183)	transcriptional regulator, TetR family protein

Closest Orthologs (e-value cutoff: 1e-4)

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	Mb0460	-	5e-87	77.89% (199)	transcriptional regulatory protein
M. gilvum PYR-GCK	Mflv_2460	-	5e-05	26.62% (154)	TetR family transcriptional regulator
M. tuberculosis H37Rv	Rv0452	-	5e-87	77.89% (199)	transcriptional regulatory protein
M. leprae Br4923	-	-	-	-	-
M. abscessus ATCC 19977	MAB_2299c	-	1e-78	70.71% (198)	transcriptional regulator
M. marinum M	MMAR_0773	-	1e-88	78.00% (200)	putative regulatory protein
M. smegmatis MC2 155	MSMEG_5282	-	2e-06	30.61% (147)	transcriptional regulator
M. thermoresistible (build 8)	-	-	-	-	-
M. ulcerans Agy99	MUL_3981	-	3e-10	31.82% (154)	putative regulatory protein
M. vanbaalenii PYR-1	Mvan_2569	-	4e-06	26.80% (153)	TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb0460|M.bovis_AF2122/97            -----------------MRYPLAVAQLGFQRARTEENKRQRAAALVEAAR
Rv0452|M.tuberculosis_H37Rv         -----------------MRYPLAVAQLGFQRARTEENKRQRAAALVEAAR
MMAR_0773|M.marinum_M               MRKGTVPGRHYPRKSRSVRYPLAVAQLTFRRARTEENKRQRAAALVEAAR
MAV_4698|M.avium_104                ---------------------------------------------MEAAR
MAB_2299c|M.abscessus_ATCC_199      -----------------------MAQLTFQRARTDEKKRQRAAAIVEAAR
MSMEG_5282|M.smegmatis_MC2_155      ----------------------MVKRSARATPGPRDDRGVLAARILAAAR
Mvan_2569|M.vanbaalenii_PYR-1       --------------------------MSKIPPGPRDERGVLSSRILVAAR
MUL_3981|M.ulcerans_Agy99           ------------------------MGGRRVKPGPRDEKGVLAAQILSVAR
Mflv_2460|M.gilvum_PYR-GCK          ---------------------------MVERWTRERRLEHTRSVLLDAAE
                                                                                 : .*.

Mb0460|M.bovis_AF2122/97            SLALETGVASVTLTAVAGRAGIHYSAVRRYFTSHKEVLLHLAAEGWARWS
Rv0452|M.tuberculosis_H37Rv         SLALETGVASVTLTAVAGRAGIHYSAVRRYFTSHKEVLLHLAAEGWARWS
MMAR_0773|M.marinum_M               SMASETGVASVTLTAVASRAGIHYSAVRRYFTSHKEVLLHLAAEGWQRWS
MAV_4698|M.avium_104                SLALETGVASVTLTAVARRAGIHYSAVRRYFTSHKEVLLHLSAEGWVRWS
MAB_2299c|M.abscessus_ATCC_199      SLAVESGVTSVTLTAVANRAGVHYSAVRRYFSSHKEVLLHLAAEGWTRWS
MSMEG_5282|M.smegmatis_MC2_155      ETFAESGWAGTTIRAVARAADVDPALVYHYYGS-KEGLLDAATDPPQKWL
Mvan_2569|M.vanbaalenii_PYR-1       GAFADTGYAGTTIRAVARAADVDPALVYHYFGS-KEALLDAATDPPQRWL
MUL_3981|M.ulcerans_Agy99           DSFAENGSAGTTVRSVARAADVDPSLIYHYFGS-KEGLLDAATMPPQRWL
Mflv_2460|M.gilvum_PYR-GCK          EVFAEKGFTPATLDDIARAAGYTKGAIYKHFDTKEELFLAVSDRYWRRYF
                                        :.* : .*:  :*  *.   . : ::: : :* :*  :     :: 

Mb0460|M.bovis_AF2122/97            GTVCEQLGEPGPMSAPRVAEALANGLAADPLFCDLLANLHLHLEQEVDVD
Rv0452|M.tuberculosis_H37Rv         GTVCEQLGEPGPMSAPRVAEALANGLAADPLFCDLLANLHLHLEQEVDVD
MMAR_0773|M.marinum_M               NTVCGELSQPGPMTESRVAAALADGLAADPLFCDLLANLHLHLEHEVEVD
MAV_4698|M.avium_104                NTVSDKLAQPGAATPSRIAETLADALADDPLFCDLLANLHLHLEHEVDAE
MAB_2299c|M.abscessus_ATCC_199      ATVCAALAEPGPGSPARVAESLVHGLVDDPLFCDLLANQHLHLEHEVDVE
MSMEG_5282|M.smegmatis_MC2_155      DAVVATWQAPVGDTGRAVLRLLLDSWADDEVGPVLRAILQTAAHEPTTHE
Mvan_2569|M.vanbaalenii_PYR-1       QNVARAWTTPVPQLGAALVRLMLDAWADEEIGPVLRAILQTAAHEAATRE
MUL_3981|M.ulcerans_Agy99           DTVAETWTTPKADLGRRLLQTLLDSWADDEIGPSLRAILLTAAHEDATRL
Mflv_2460|M.gilvum_PYR-GCK          DNFAEVMSS-ASRVGADELDEIAERWRQLSIDRG-AEHAALGLEFTLYLL
                                      .                  : .      :            .      

Mb0460|M.bovis_AF2122/97            RVIEVKRTSIAAVIALVDAIESALPALGRSGAFDILLAAYSLAATLWQIA
Rv0452|M.tuberculosis_H37Rv         RVIEVKRTSIAAVIALVDAIESALPALGRSGAFDILLAAYSLAATLWQIA
MMAR_0773|M.marinum_M               RVVEVKRTSTAAVIALADAIENALPALGRAGAFDVLLAAYSLGATLWQIA
MAV_4698|M.avium_104                RVVEVKRISTAATLSLADSIQRALPELGRSGSLDILLAAYSLAATLWQVA
MAB_2299c|M.abscessus_ATCC_199      RVAEVKQISNVAVMSIAESIERTLPEIGRKGSLDILVAGFSLAAMLWQIA
MSMEG_5282|M.smegmatis_MC2_155      KLRKVVERSLIGVIATMGDDERVR--RTRAGLVASQTIGFALMRYVWRIE
Mvan_2569|M.vanbaalenii_PYR-1       KLRLVVERSLMG-VSQLGVDERDR--MLRSGLISSQIMGLAMMRYVWRIE
MUL_3981|M.ulcerans_Agy99           KLRRIVESSLIG-VSQLDTDEDDR--LTRSGLIASQLIGLAMTRYVWQIE
Mflv_2460|M.gilvum_PYR-GCK          RNPEARERVEAKRAEVVDQLAEFIVEGMSQLGATLLIEPSTFARALVATS
                                    :     .                                 ::   :    

Mb0460|M.bovis_AF2122/97            NPPERLTDAYAEEPELLPPEWNLDFAAALTRLLTATLLGLLAGSPCECRS
Rv0452|M.tuberculosis_H37Rv         NPPERLTDAYAEEPELLPPEWNLDFAAALTRLLTATLLGLLAGSPCECRS
MMAR_0773|M.marinum_M               NPPQRLTDVYAEEPDVLPPEWNLDFAAALTRLLTATCCGLTAKSS-----
MAV_4698|M.avium_104                NPPERLTDAYAEEPEVVPPEWNLDFASALTRLLTATCIGLIPQSA-----
MAB_2299c|M.abscessus_ATCC_199      HPPEGLEHDYRSEP-GVPPDWSLDFEPALTRLLTATCIGIVEQKH-----
MSMEG_5282|M.smegmatis_MC2_155      -PVASMREDEVLDAVGPTLQRYIDGDIGAAGQIRTGFDTA----------
Mvan_2569|M.vanbaalenii_PYR-1       -PVASMDDDELVAAVAPNLQRYISDDLG----------------------
MUL_3981|M.ulcerans_Agy99           -PIASMSDSEVLAAITPNLQRYIDGDLHPTKNSPAQRPRRTRRP------
Mflv_2460|M.gilvum_PYR-GCK          DSVVLGSQLDAVDLYRPMVEMYVSVIKLPD--------------------
                                     .     .           :  :.                          

Mb0460|M.bovis_AF2122/97            PTR
Rv0452|M.tuberculosis_H37Rv         PTR
MMAR_0773|M.marinum_M               ---
MAV_4698|M.avium_104                ---
MAB_2299c|M.abscessus_ATCC_199      ---
MSMEG_5282|M.smegmatis_MC2_155      ---
Mvan_2569|M.vanbaalenii_PYR-1       ---
MUL_3981|M.ulcerans_Agy99           ---
Mflv_2460|M.gilvum_PYR-GCK          ---