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M. abscessus ATCC 19977 MAB_1136 (-)

annotation: transcriptional regulator TetR
coordinates: 1149587 - 1150243
length: 218

MTSLSFRRARSEENKRQRAATIVEAARALALESGVASVTLTGLANRAGVHHSAVRRYFSSHKEVLLRLST
EGMAALAESVCAALEGSQERSPIEVGAILSGALVDAPLFCDLLGSHYVHFEHEVVIDHVREAQRVNQAAA
MTIVEAIERSAPQIDREGALDIVISSFALAAMLWQFAHPPKGLEHDFSNEPGIPDDWDTDFGSTLTRLLT
ATCIGAAK
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_1136--100% (218)transcriptional regulator TetR
M. abscessus ATCC 19977MAB_2299c-4e-7360.47% (215) transcriptional regulator
M. abscessus ATCC 19977MAB_4312-1e-1726.48% (219) TetR family transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0460-9e-5952.31% (216) transcriptional regulatory protein
M. gilvum PYR-GCKMflv_2452-6e-0630.30% (99) TetR family transcriptional regulator
M. tuberculosis H37RvRv0452-9e-5952.31% (216) transcriptional regulatory protein
M. leprae Br4923-----
M. marinum MMMAR_0773-9e-6050.93% (216) putative regulatory protein
M. avium 104MAV_4698-1e-5351.55% (194) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_2898-5e-0731.25% (112) transcriptional regulator, TetR family protein
M. thermoresistible (build 8)TH_0258-1e-0528.12% (96) transcriptional repressor, TetR family protein, putative
M. ulcerans Agy99MUL_2639-4e-0626.88% (160) transcriptional regulatory protein
M. vanbaalenii PYR-1Mvan_4199-4e-0631.31% (99) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_0773|M.marinum_M               --------------------------------------------------
MAV_4698|M.avium_104                --------------------------------------------------
Mb0460|M.bovis_AF2122/97            --------------------------------------------------
Rv0452|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_1136|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_2452|M.gilvum_PYR-GCK          ------------MSPS---RQP----------------------------
Mvan_4199|M.vanbaalenii_PYR-1       MPHKPGREERRQLEPSGDERQQGEHQRGGPQHTHATHSAEDDLQVPIVRL
TH_0258|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2898|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2639|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

MMAR_0773|M.marinum_M               -----MRKGTVPGRHYPRKSRSVRYPLAVAQLTFRRARTEENKRQRAAAL
MAV_4698|M.avium_104                --------------------------------------------------
Mb0460|M.bovis_AF2122/97            ----------------------MRYPLAVAQLGFQRARTEENKRQRAAAL
Rv0452|M.tuberculosis_H37Rv         ----------------------MRYPLAVAQLGFQRARTEENKRQRAAAL
MAB_1136|M.abscessus_ATCC_1997      ----------------------------MTSLSFRRARSEENKRQRAATI
Mflv_2452|M.gilvum_PYR-GCK          ---------AMFRHMPDAKNP-MAADRGQRRASFQRADSRETQR----TL
Mvan_4199|M.vanbaalenii_PYR-1       RSTIGSHDFACYLHDVAATRPDTQPDHGQRRASFQRARSRETKR----ML
TH_0258|M.thermoresistible__bu      ---------------------VSRADGGQRRASYQRARSRETKR----AL
MSMEG_2898|M.smegmatis_MC2_155      ----------------------------MPRVSREQMQSN------RAAV
MUL_2639|M.ulcerans_Agy99           ----------------------------------MSERSQYHHGGLRDAI
                                                                                      

MMAR_0773|M.marinum_M               VEAARSMASETGVASVTLTAVASRAGIHYSAVRRYFTSHKEVLLHLAAEG
MAV_4698|M.avium_104                MEAARSLALETGVASVTLTAVARRAGIHYSAVRRYFTSHKEVLLHLSAEG
Mb0460|M.bovis_AF2122/97            VEAARSLALETGVASVTLTAVAGRAGIHYSAVRRYFTSHKEVLLHLAAEG
Rv0452|M.tuberculosis_H37Rv         VEAARSLALETGVASVTLTAVAGRAGIHYSAVRRYFTSHKEVLLHLAAEG
MAB_1136|M.abscessus_ATCC_1997      VEAARALALESGVASVTLTGLANRAGVHHSAVRRYFSSHKEVLLRLSTEG
Mflv_2452|M.gilvum_PYR-GCK          IQAAMALWRTKGYAATTVADICTAAGVSKALFYFYFPRKEDVLFEVGVLS
Mvan_4199|M.vanbaalenii_PYR-1       VQAAMALWRTKGYATTTVADICTAAGVSKALFYFYFPRKEDVLFEVGVLS
TH_0258|M.thermoresistible__bu      VQAAMALWRTNGYANTTVADICRAAGVSRALFYFYFPAKEDILFEVGLLS
MSMEG_2898|M.smegmatis_MC2_155      VQAASELIRERGMADVTVDAISARAGLTHGSFHKQFASKQALLLEAICAA
MUL_2639|M.ulcerans_Agy99           LTEAATLVAERGVGAVSVRELARRAGVSHNAYGHHFTDRRGLFTALAAQG
                                    :  *  :    * . .::  :.  **:        *. :. ::      .

MMAR_0773|M.marinum_M               WQRWSNTVCGELSQPGPMTESRVAAA--LADGLAADP--LFCDLLANLHL
MAV_4698|M.avium_104                WVRWSNTVSDKLAQPGAATPSRIAET--LADALADDP--LFCDLLANLHL
Mb0460|M.bovis_AF2122/97            WARWSGTVCEQLGEPGPMSAPRVAEA--LANGLAADP--LFCDLLANLHL
Rv0452|M.tuberculosis_H37Rv         WARWSGTVCEQLGEPGPMSAPRVAEA--LANGLAADP--LFCDLLANLHL
MAB_1136|M.abscessus_ATCC_1997      MAALAESVCAALEGSQERSPIEVGAI--LSGALVDAP--LFCDLLGSHYV
Mflv_2452|M.gilvum_PYR-GCK          TKAAHRRIHALLKKPYEIESVIAGALTAFEQSMARNPKDLVIETILEGYR
Mvan_4199|M.vanbaalenii_PYR-1       TQSAHRTIHALLKKPYEIESVVSAALTAFERSMARNPRELIIETILEGYR
TH_0258|M.thermoresistible__bu      TQAARRRIRSLLRGDYDVDSVIAAALRSLERSMARNPRELIVQTILEGYR
MSMEG_2898|M.smegmatis_MC2_155      VDQRRAAVQKTVEEHGSDAPDVLKDWY-LSEEHRDNP---ATGCAVAALV
MUL_2639|M.ulcerans_Agy99           FMLLAEALREARGNFLDGARAYVRFA-------IGHPG--HYAVMFDWSL
                                           :                            *             

MMAR_0773|M.marinum_M               HLEHEVEVDRVVEVKRTSTAAVIALADAIENALPALGRAGAFDVLLAAYS
MAV_4698|M.avium_104                HLEHEVDAERVVEVKRISTAATLSLADSIQRALPELGRSGSLDILLAAYS
Mb0460|M.bovis_AF2122/97            HLEQEVDVDRVIEVKRTSIAAVIALVDAIESALPALGRSGAFDILLAAYS
Rv0452|M.tuberculosis_H37Rv         HLEQEVDVDRVIEVKRTSIAAVIALVDAIESALPALGRSGAFDILLAAYS
MAB_1136|M.abscessus_ATCC_1997      HFEHEVVIDHVREAQRVNQAAAMTIVEAIERSAPQIDREGALDIVISSFA
Mflv_2452|M.gilvum_PYR-GCK          HEHRLMAGGGHPDPDADMFTELFTRARDDGKLPASVDPVHLAYLAQTMVS
Mvan_4199|M.vanbaalenii_PYR-1       HEHRIMADGSPPDVDADMFTELFTRARSDGKLPGTVDTAHLAYLAQTMVS
TH_0258|M.thermoresistible__bu      HEHRILAGEEDPATGADMFGELFTRAQQDGKLAAGIDVDHLSRVAQMLVS
MSMEG_2898|M.smegmatis_MC2_155      GHAATVTDDALRDAYCRAVGDLLAMIEDGG------TADAFGEVALMVGA
MUL_2639|M.ulcerans_Agy99           IDRTDSDLAAAHAAASMELARSASLLQDPKAVADRHGAELAAWSLIHGFS
                                                           :                         :

MMAR_0773|M.marinum_M               LGATLWQIANPPQR-LTDVYAEEPDVLPPEWNLDFAAALTRLLTATCCGL
MAV_4698|M.avium_104                LAATLWQVANPPER-LTDAYAEEPEVVPPEWNLDFASALTRLLTATCIGL
Mb0460|M.bovis_AF2122/97            LAATLWQIANPPER-LTDAYAEEPELLPPEWNLDFAAALTRLLTATLLGL
Rv0452|M.tuberculosis_H37Rv         LAATLWQIANPPER-LTDAYAEEPELLPPEWNLDFAAALTRLLTATLLGL
MAB_1136|M.abscessus_ATCC_1997      LAAMLWQFAHPPKG-LEHDFSNEP-GIPDDWDTDFGSTLTRLLTATCIGA
Mflv_2452|M.gilvum_PYR-GCK          EGSRHWAAGAFGDRSFAEVVTGDICTLVNGY---------RHTP------
Mvan_4199|M.vanbaalenii_PYR-1       EGARHWAAGAFGSRSFAEVVTADICTLVNGYTARRPHVEFRDRP------
TH_0258|M.thermoresistible__bu      EGVRHWAAGGFGDRSFTEVVAGDIAALIDGYN-------LRLRR------
MSMEG_2898|M.smegmatis_MC2_155      LELARATKGTPLSARFLESARQRLSRQE----------------------
MUL_2639|M.ulcerans_Agy99           MLWLNGVLPSDPGECTDPIATAERVALMLFET------------------
                                                                                      

MMAR_0773|M.marinum_M               TAKSS--------
MAV_4698|M.avium_104                IPQSA--------
Mb0460|M.bovis_AF2122/97            LAGSPCECRSPTR
Rv0452|M.tuberculosis_H37Rv         LAGSPCECRSPTR
MAB_1136|M.abscessus_ATCC_1997      AK-----------
Mflv_2452|M.gilvum_PYR-GCK          -------------
Mvan_4199|M.vanbaalenii_PYR-1       -------------
TH_0258|M.thermoresistible__bu      -------------
MSMEG_2898|M.smegmatis_MC2_155      -------------
MUL_2639|M.ulcerans_Agy99           -------------