For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTSLSFRRARSEENKRQRAATIVEAARALALESGVASVTLTGLANRAGVHHSAVRRYFSSHKEVLLRLST EGMAALAESVCAALEGSQERSPIEVGAILSGALVDAPLFCDLLGSHYVHFEHEVVIDHVREAQRVNQAAA MTIVEAIERSAPQIDREGALDIVISSFALAAMLWQFAHPPKGLEHDFSNEPGIPDDWDTDFGSTLTRLLT ATCIGAAK
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_1136 | - | - | 100% (218) | transcriptional regulator TetR |
M. abscessus ATCC 19977 | MAB_2299c | - | 4e-73 | 60.47% (215) | transcriptional regulator |
M. abscessus ATCC 19977 | MAB_4312 | - | 1e-17 | 26.48% (219) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0460 | - | 9e-59 | 52.31% (216) | transcriptional regulatory protein |
M. gilvum PYR-GCK | Mflv_2452 | - | 6e-06 | 30.30% (99) | TetR family transcriptional regulator |
M. tuberculosis H37Rv | Rv0452 | - | 9e-59 | 52.31% (216) | transcriptional regulatory protein |
M. leprae Br4923 | - | - | - | - | - |
M. marinum M | MMAR_0773 | - | 9e-60 | 50.93% (216) | putative regulatory protein |
M. avium 104 | MAV_4698 | - | 1e-53 | 51.55% (194) | transcriptional regulator, TetR family protein |
M. smegmatis MC2 155 | MSMEG_2898 | - | 5e-07 | 31.25% (112) | transcriptional regulator, TetR family protein |
M. thermoresistible (build 8) | TH_0258 | - | 1e-05 | 28.12% (96) | transcriptional repressor, TetR family protein, putative |
M. ulcerans Agy99 | MUL_2639 | - | 4e-06 | 26.88% (160) | transcriptional regulatory protein |
M. vanbaalenii PYR-1 | Mvan_4199 | - | 4e-06 | 31.31% (99) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_0773|M.marinum_M -------------------------------------------------- MAV_4698|M.avium_104 -------------------------------------------------- Mb0460|M.bovis_AF2122/97 -------------------------------------------------- Rv0452|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1136|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_2452|M.gilvum_PYR-GCK ------------MSPS---RQP---------------------------- Mvan_4199|M.vanbaalenii_PYR-1 MPHKPGREERRQLEPSGDERQQGEHQRGGPQHTHATHSAEDDLQVPIVRL TH_0258|M.thermoresistible__bu -------------------------------------------------- MSMEG_2898|M.smegmatis_MC2_155 -------------------------------------------------- MUL_2639|M.ulcerans_Agy99 -------------------------------------------------- MMAR_0773|M.marinum_M -----MRKGTVPGRHYPRKSRSVRYPLAVAQLTFRRARTEENKRQRAAAL MAV_4698|M.avium_104 -------------------------------------------------- Mb0460|M.bovis_AF2122/97 ----------------------MRYPLAVAQLGFQRARTEENKRQRAAAL Rv0452|M.tuberculosis_H37Rv ----------------------MRYPLAVAQLGFQRARTEENKRQRAAAL MAB_1136|M.abscessus_ATCC_1997 ----------------------------MTSLSFRRARSEENKRQRAATI Mflv_2452|M.gilvum_PYR-GCK ---------AMFRHMPDAKNP-MAADRGQRRASFQRADSRETQR----TL Mvan_4199|M.vanbaalenii_PYR-1 RSTIGSHDFACYLHDVAATRPDTQPDHGQRRASFQRARSRETKR----ML TH_0258|M.thermoresistible__bu ---------------------VSRADGGQRRASYQRARSRETKR----AL MSMEG_2898|M.smegmatis_MC2_155 ----------------------------MPRVSREQMQSN------RAAV MUL_2639|M.ulcerans_Agy99 ----------------------------------MSERSQYHHGGLRDAI MMAR_0773|M.marinum_M VEAARSMASETGVASVTLTAVASRAGIHYSAVRRYFTSHKEVLLHLAAEG MAV_4698|M.avium_104 MEAARSLALETGVASVTLTAVARRAGIHYSAVRRYFTSHKEVLLHLSAEG Mb0460|M.bovis_AF2122/97 VEAARSLALETGVASVTLTAVAGRAGIHYSAVRRYFTSHKEVLLHLAAEG Rv0452|M.tuberculosis_H37Rv VEAARSLALETGVASVTLTAVAGRAGIHYSAVRRYFTSHKEVLLHLAAEG MAB_1136|M.abscessus_ATCC_1997 VEAARALALESGVASVTLTGLANRAGVHHSAVRRYFSSHKEVLLRLSTEG Mflv_2452|M.gilvum_PYR-GCK IQAAMALWRTKGYAATTVADICTAAGVSKALFYFYFPRKEDVLFEVGVLS Mvan_4199|M.vanbaalenii_PYR-1 VQAAMALWRTKGYATTTVADICTAAGVSKALFYFYFPRKEDVLFEVGVLS TH_0258|M.thermoresistible__bu VQAAMALWRTNGYANTTVADICRAAGVSRALFYFYFPAKEDILFEVGLLS MSMEG_2898|M.smegmatis_MC2_155 VQAASELIRERGMADVTVDAISARAGLTHGSFHKQFASKQALLLEAICAA MUL_2639|M.ulcerans_Agy99 LTEAATLVAERGVGAVSVRELARRAGVSHNAYGHHFTDRRGLFTALAAQG : * : * . .:: :. **: *. :. :: . MMAR_0773|M.marinum_M WQRWSNTVCGELSQPGPMTESRVAAA--LADGLAADP--LFCDLLANLHL MAV_4698|M.avium_104 WVRWSNTVSDKLAQPGAATPSRIAET--LADALADDP--LFCDLLANLHL Mb0460|M.bovis_AF2122/97 WARWSGTVCEQLGEPGPMSAPRVAEA--LANGLAADP--LFCDLLANLHL Rv0452|M.tuberculosis_H37Rv WARWSGTVCEQLGEPGPMSAPRVAEA--LANGLAADP--LFCDLLANLHL MAB_1136|M.abscessus_ATCC_1997 MAALAESVCAALEGSQERSPIEVGAI--LSGALVDAP--LFCDLLGSHYV Mflv_2452|M.gilvum_PYR-GCK TKAAHRRIHALLKKPYEIESVIAGALTAFEQSMARNPKDLVIETILEGYR Mvan_4199|M.vanbaalenii_PYR-1 TQSAHRTIHALLKKPYEIESVVSAALTAFERSMARNPRELIIETILEGYR TH_0258|M.thermoresistible__bu TQAARRRIRSLLRGDYDVDSVIAAALRSLERSMARNPRELIVQTILEGYR MSMEG_2898|M.smegmatis_MC2_155 VDQRRAAVQKTVEEHGSDAPDVLKDWY-LSEEHRDNP---ATGCAVAALV MUL_2639|M.ulcerans_Agy99 FMLLAEALREARGNFLDGARAYVRFA-------IGHPG--HYAVMFDWSL : * MMAR_0773|M.marinum_M HLEHEVEVDRVVEVKRTSTAAVIALADAIENALPALGRAGAFDVLLAAYS MAV_4698|M.avium_104 HLEHEVDAERVVEVKRISTAATLSLADSIQRALPELGRSGSLDILLAAYS Mb0460|M.bovis_AF2122/97 HLEQEVDVDRVIEVKRTSIAAVIALVDAIESALPALGRSGAFDILLAAYS Rv0452|M.tuberculosis_H37Rv HLEQEVDVDRVIEVKRTSIAAVIALVDAIESALPALGRSGAFDILLAAYS MAB_1136|M.abscessus_ATCC_1997 HFEHEVVIDHVREAQRVNQAAAMTIVEAIERSAPQIDREGALDIVISSFA Mflv_2452|M.gilvum_PYR-GCK HEHRLMAGGGHPDPDADMFTELFTRARDDGKLPASVDPVHLAYLAQTMVS Mvan_4199|M.vanbaalenii_PYR-1 HEHRIMADGSPPDVDADMFTELFTRARSDGKLPGTVDTAHLAYLAQTMVS TH_0258|M.thermoresistible__bu HEHRILAGEEDPATGADMFGELFTRAQQDGKLAAGIDVDHLSRVAQMLVS MSMEG_2898|M.smegmatis_MC2_155 GHAATVTDDALRDAYCRAVGDLLAMIEDGG------TADAFGEVALMVGA MUL_2639|M.ulcerans_Agy99 IDRTDSDLAAAHAAASMELARSASLLQDPKAVADRHGAELAAWSLIHGFS : : MMAR_0773|M.marinum_M LGATLWQIANPPQR-LTDVYAEEPDVLPPEWNLDFAAALTRLLTATCCGL MAV_4698|M.avium_104 LAATLWQVANPPER-LTDAYAEEPEVVPPEWNLDFASALTRLLTATCIGL Mb0460|M.bovis_AF2122/97 LAATLWQIANPPER-LTDAYAEEPELLPPEWNLDFAAALTRLLTATLLGL Rv0452|M.tuberculosis_H37Rv LAATLWQIANPPER-LTDAYAEEPELLPPEWNLDFAAALTRLLTATLLGL MAB_1136|M.abscessus_ATCC_1997 LAAMLWQFAHPPKG-LEHDFSNEP-GIPDDWDTDFGSTLTRLLTATCIGA Mflv_2452|M.gilvum_PYR-GCK EGSRHWAAGAFGDRSFAEVVTGDICTLVNGY---------RHTP------ Mvan_4199|M.vanbaalenii_PYR-1 EGARHWAAGAFGSRSFAEVVTADICTLVNGYTARRPHVEFRDRP------ TH_0258|M.thermoresistible__bu EGVRHWAAGGFGDRSFTEVVAGDIAALIDGYN-------LRLRR------ MSMEG_2898|M.smegmatis_MC2_155 LELARATKGTPLSARFLESARQRLSRQE---------------------- MUL_2639|M.ulcerans_Agy99 MLWLNGVLPSDPGECTDPIATAERVALMLFET------------------ MMAR_0773|M.marinum_M TAKSS-------- MAV_4698|M.avium_104 IPQSA-------- Mb0460|M.bovis_AF2122/97 LAGSPCECRSPTR Rv0452|M.tuberculosis_H37Rv LAGSPCECRSPTR MAB_1136|M.abscessus_ATCC_1997 AK----------- Mflv_2452|M.gilvum_PYR-GCK ------------- Mvan_4199|M.vanbaalenii_PYR-1 ------------- TH_0258|M.thermoresistible__bu ------------- MSMEG_2898|M.smegmatis_MC2_155 ------------- MUL_2639|M.ulcerans_Agy99 -------------