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AQLTFQRARTDEKKRQRAAAIVEAARSLAVESGVTSVTLTAVANRAGVHYSAVRRYFSSHKEVLLHLAAE GWTRWSATVCAALAEPGPGSPARVAESLVHGLVDDPLFCDLLANQHLHLEHEVDVERVAEVKQISNVAVM SIAESIERTLPEIGRKGSLDILVAGFSLAAMLWQIAHPPEGLEHDYRSEPGVPPDWSLDFEPALTRLLTA TCIGIVEQKH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2299c | - | - | 100% (221) | transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1136 | - | 4e-73 | 60.47% (215) | transcriptional regulator TetR |
| M. abscessus ATCC 19977 | MAB_4312 | - | 2e-17 | 26.58% (222) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0460 | - | 2e-83 | 69.72% (218) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_4816 | - | 4e-05 | 34.04% (94) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0452 | - | 2e-83 | 69.72% (218) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0773 | - | 3e-83 | 68.20% (217) | putative regulatory protein |
| M. avium 104 | MAV_4698 | - | 1e-78 | 70.71% (198) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5282 | - | 3e-08 | 31.48% (162) | transcriptional regulator |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_3981 | - | 2e-07 | 27.44% (164) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_2569 | - | 3e-06 | 25.44% (169) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0460|M.bovis_AF2122/97 ----------------------------MRYPLAVAQLGFQRARTEENKR
Rv0452|M.tuberculosis_H37Rv ----------------------------MRYPLAVAQLGFQRARTEENKR
MMAR_0773|M.marinum_M -----------MRKGTVPGRHYPRKSRSVRYPLAVAQLTFRRARTEENKR
MAV_4698|M.avium_104 --------------------------------------------------
MAB_2299c|M.abscessus_ATCC_199 ----------------------------------MAQLTFQRARTDEKKR
MSMEG_5282|M.smegmatis_MC2_155 ---------------------------------MVKRSARATPGPRDDRG
Mvan_2569|M.vanbaalenii_PYR-1 -------------------------------------MSKIPPGPRDERG
MUL_3981|M.ulcerans_Agy99 -----------------------------------MGGRRVKPGPRDEKG
Mflv_4816|M.gilvum_PYR-GCK MGSRQEISAACGRFHTVNSRTPSSRRGHSSRSRSKDGNSRETLSREERKE
Mb0460|M.bovis_AF2122/97 QRAAALVEAARSLALETGVASVTLTAVAGRAGIHYSAVRRYFTSHKEVLL
Rv0452|M.tuberculosis_H37Rv QRAAALVEAARSLALETGVASVTLTAVAGRAGIHYSAVRRYFTSHKEVLL
MMAR_0773|M.marinum_M QRAAALVEAARSMASETGVASVTLTAVASRAGIHYSAVRRYFTSHKEVLL
MAV_4698|M.avium_104 ------MEAARSLALETGVASVTLTAVARRAGIHYSAVRRYFTSHKEVLL
MAB_2299c|M.abscessus_ATCC_199 QRAAAIVEAARSLAVESGVTSVTLTAVANRAGVHYSAVRRYFSSHKEVLL
MSMEG_5282|M.smegmatis_MC2_155 VLAARILAAARETFAESGWAGTTIRAVARAADVDPALVYHYYGS-KEGLL
Mvan_2569|M.vanbaalenii_PYR-1 VLSSRILVAARGAFADTGYAGTTIRAVARAADVDPALVYHYFGS-KEALL
MUL_3981|M.ulcerans_Agy99 VLAAQILSVARDSFAENGSAGTTVRSVARAADVDPSLIYHYFGS-KEGLL
Mflv_4816|M.gilvum_PYR-GCK ATRRAIVDAALHLLAERGFSALSLREVTREAGIVPAAFYRHFDSMEALGL
: .* : * :. :: *: *.: : . ::: * : *
Mb0460|M.bovis_AF2122/97 HLAAEGWARWSGTVCEQLGEPGPMSAPRVAEALANGLAADPLFCDLLANL
Rv0452|M.tuberculosis_H37Rv HLAAEGWARWSGTVCEQLGEPGPMSAPRVAEALANGLAADPLFCDLLANL
MMAR_0773|M.marinum_M HLAAEGWQRWSNTVCGELSQPGPMTESRVAAALADGLAADPLFCDLLANL
MAV_4698|M.avium_104 HLSAEGWVRWSNTVSDKLAQPGAATPSRIAETLADALADDPLFCDLLANL
MAB_2299c|M.abscessus_ATCC_199 HLAAEGWTRWSATVCAALAEPGPGSPARVAESLVHGLVDDPLFCDLLANQ
MSMEG_5282|M.smegmatis_MC2_155 DAATDPPQKWLDAVVATWQAPVGDTGRAVLRLLLDSWADDEVGPVLRAIL
Mvan_2569|M.vanbaalenii_PYR-1 DAATDPPQRWLQNVARAWTTPVPQLGAALVRLMLDAWADEEIGPVLRAIL
MUL_3981|M.ulcerans_Agy99 DAATMPPQRWLDTVAETWTTPKADLGRRLLQTLLDSWADDEIGPSLRAIL
Mflv_4816|M.gilvum_PYR-GCK VLIDESFRSLREMLRGAR--AGKLDPNRVIESSVDILIDG-VQQRREHWR
: . : . :
Mb0460|M.bovis_AF2122/97 HLHLEQEVDVDRVIEVKRTSIAAVIALVDAIESALPALGRSGAFDILLAA
Rv0452|M.tuberculosis_H37Rv HLHLEQEVDVDRVIEVKRTSIAAVIALVDAIESALPALGRSGAFDILLAA
MMAR_0773|M.marinum_M HLHLEHEVEVDRVVEVKRTSTAAVIALADAIENALPALGRAGAFDVLLAA
MAV_4698|M.avium_104 HLHLEHEVDAERVVEVKRISTAATLSLADSIQRALPELGRSGSLDILLAA
MAB_2299c|M.abscessus_ATCC_199 HLHLEHEVDVERVAEVKQISNVAVMSIAESIERTLPEIGRKGSLDILVAG
MSMEG_5282|M.smegmatis_MC2_155 QTAAHEPTTHEKLRKVVERSLIGVIATMGDDERVR--RTRAGLVASQTIG
Mvan_2569|M.vanbaalenii_PYR-1 QTAAHEAATREKLRLVVERSLMG-VSQLGVDERDR--MLRSGLISSQIMG
MUL_3981|M.ulcerans_Agy99 LTAAHEDATRLKLRRIVESSLIG-VSQLDTDEDDR--LTRSGLIASQLIG
Mflv_4816|M.gilvum_PYR-GCK FIGRERSTGVTVLRYAIRTEIRLITSELAIDLARFPALNTWSSEDLNILA
.. . : . . : . .
Mb0460|M.bovis_AF2122/97 YSLAATLWQIANPPERLTDAYAEEPELLPPEWNLDFAAALTRLLTATLLG
Rv0452|M.tuberculosis_H37Rv YSLAATLWQIANPPERLTDAYAEEPELLPPEWNLDFAAALTRLLTATLLG
MMAR_0773|M.marinum_M YSLGATLWQIANPPQRLTDVYAEEPDVLPPEWNLDFAAALTRLLTATCCG
MAV_4698|M.avium_104 YSLAATLWQVANPPERLTDAYAEEPEVVPPEWNLDFASALTRLLTATCIG
MAB_2299c|M.abscessus_ATCC_199 FSLAAMLWQIAHPPEGLEHDYRSEP-GVPPDWSLDFEPALTRLLTATCIG
MSMEG_5282|M.smegmatis_MC2_155 FALMRYVWRIE-PVASMREDEVLDAVGPTLQRYIDGDIGAAGQIRTGFDT
Mvan_2569|M.vanbaalenii_PYR-1 LAMMRYVWRIE-PVASMDDDELVAAVAPNLQRYISDDLG-----------
MUL_3981|M.ulcerans_Agy99 LAMTRYVWQIE-PIASMSDSEVLAAITPNLQRYIDGDLHPTKNSPAQRPR
Mflv_4816|M.gilvum_PYR-GCK SVFVNSMIAIAEQLEDVTDTASVDEIRRTAVKQLRMITVGVAGWRSG---
: : : : . :
Mb0460|M.bovis_AF2122/97 LLAGSPCECRSPTR
Rv0452|M.tuberculosis_H37Rv LLAGSPCECRSPTR
MMAR_0773|M.marinum_M LTAKSS--------
MAV_4698|M.avium_104 LIPQSA--------
MAB_2299c|M.abscessus_ATCC_199 IVEQKH--------
MSMEG_5282|M.smegmatis_MC2_155 A-------------
Mvan_2569|M.vanbaalenii_PYR-1 --------------
MUL_3981|M.ulcerans_Agy99 RTRRP---------
Mflv_4816|M.gilvum_PYR-GCK --------------