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NRRTPSTRTRRSETSRSRDTLTREERKEATRRALIAAALKLLKDHSFSALSLREVTREAGIVPAAFYRHF DSMDALGLVLIDESFRSLRDMLRGARAGKLDPHHVIESSAEILVSSFNERREHWRFIARERSGGASALRY AIRTEIRLITSELAIDLARFPALKDWSSEDLNILANLFVNSMISLAEALEDAADAESIEAIHRTAVKQMR MIAVGVNGWRSTD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1741 | - | - | 100% (224) | TetR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_6807 | - | 2e-07 | 28.21% (117) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6032 | - | 2e-07 | 21.76% (193) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1846 | - | 4e-06 | 31.08% (74) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_4816 | - | 1e-90 | 74.89% (227) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1816 | - | 4e-06 | 31.08% (74) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_00064 | - | 2e-05 | 31.51% (73) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1424c | - | 2e-35 | 40.50% (200) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0334 | - | 2e-90 | 76.13% (222) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5169 | - | 2e-85 | 74.65% (213) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1635 | - | 6e-07 | 31.46% (89) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4787 | - | 2e-90 | 75.68% (222) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1626 | - | 2e-90 | 75.78% (223) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0334|M.marinum_M ----------------MNERTPSSRPHRS--GRSRD-----SPSREERKE
MUL_4787|M.ulcerans_Agy99 ----------------MNERTPSSRPHRS--SRSRD-----SPSREERKE
MAV_5169|M.avium_104 -----------------------MRGSGR--ERSRE-----SQSREERKE
MSMEG_1741|M.smegmatis_MC2_155 ----------------MNRRTPSTRTRRSETSRSRD-----TLTREERKE
Mflv_4816|M.gilvum_PYR-GCK MGSRQEISAACGRFHTVNSRTPSSRRGHSSRSRSKDGNSRETLSREERKE
Mvan_1626|M.vanbaalenii_PYR-1 ----------------MNSRTPSSRSGRS-RSREKD-----TLSREERKE
MAB_1424c|M.abscessus_ATCC_199 -----------------------MR-----------------HSRAEKKL
Mb1846|M.bovis_AF2122/97 -------------------MCQTCR----------------VGKRRDARE
Rv1816|M.tuberculosis_H37Rv -------------------MCQTCR----------------VGKRRDARE
MLBr_00064|M.leprae_Br4923 ---------------MINSTAGQTSQSRS------------RRSTRPSGD
TH_1635|M.thermoresistible__bu -----------------VTTDSPAR-----------------EDRRSRGD
MMAR_0334|M.marinum_M ATRRAIIAAALKLVHDRSFSALSLREVTREAGIVPAAFYRHFESMEALGL
MUL_4787|M.ulcerans_Agy99 ATRRAIIAAALKLVHDRSFSALSLREVTREAGIVPAAFYRHFESMEALGL
MAV_5169|M.avium_104 ATRRAIIAAALKLLQDRSFSSLSLREVTREVGIVPAAFYRHFESMESLGL
MSMEG_1741|M.smegmatis_MC2_155 ATRRALIAAALKLLKDHSFSALSLREVTREAGIVPAAFYRHFDSMDALGL
Mflv_4816|M.gilvum_PYR-GCK ATRRAIVDAALHLLAERGFSALSLREVTREAGIVPAAFYRHFDSMEALGL
Mvan_1626|M.vanbaalenii_PYR-1 ATRRAIVAAALSLLAERSFSGLSLREVTREAGIVPAAFYRHFESMEALGL
MAB_1424c|M.abscessus_ATCC_199 HTRRTLLDGTLELLKVRGFAAVSLREVAKSAGLVPTAFYRHFESMEDLGT
Mb1846|M.bovis_AF2122/97 QIEAKIVELGRRQLLDHGAAGLSLRAIARNLGMVSSAVYRYVSSRDELLT
Rv1816|M.tuberculosis_H37Rv QIEAKIVELGRRQLLDHGAAGLSLRAIARNLGMVSSAVYRYVSSRDELLT
MLBr_00064|M.leprae_Br4923 DRELAILATAEQLLEDRPLTEISVDYLAKSAGISRPTFYFYFASKEAVLL
TH_1635|M.thermoresistible__bu RQRDAIVAAVRELLEERSFADLSVSTISERAGVARSGFYFYFDSKYAVLA
. :: : : : :*: ::. *: . .* :. * :
MMAR_0334|M.marinum_M VLIDESFRTLRDTLRGAR--AGRLDPNRVIESSVEILIGSVAERREHWR-
MUL_4787|M.ulcerans_Agy99 VLIDESFRTLRDTLRGAR--AGRLDPNRVIESSVEILIGSVAERREHWR-
MAV_5169|M.avium_104 VLIDESFRSLRDTLRDAR--AGKLDPNRVIESSVEILVASVADRREHWR-
MSMEG_1741|M.smegmatis_MC2_155 VLIDESFRSLRDMLRGAR--AGKLDPHHVIESSAEILVSSFNERREHWR-
Mflv_4816|M.gilvum_PYR-GCK VLIDESFRSLREMLRGAR--AGKLDPNRVIESSVDILIDGVQQRREHWR-
Mvan_1626|M.vanbaalenii_PYR-1 VLIDESFRALREMLRGAR--AGKLDPNRVIESSVDILIDSVQQRREHWR-
MAB_1424c|M.abscessus_ATCC_199 VLAEESVHALRDTFRQARREAGSDNPAKILR----LMVDRVNEHANNFR-
Mb1846|M.bovis_AF2122/97 LLLVDAYSDLADTVDRARDDTVADSWSDDVIAIARAVRGWAVTNPARWA-
Rv1816|M.tuberculosis_H37Rv LLLVDAYSDLADTVDRARDDTVADSWSDDVIAIARAVRGWAVTNPARWA-
MLBr_00064|M.leprae_Br4923 TLLDRVFNKANAALETLIKNRDNKRGNKWRTGINVFFETFGSHKAVTCAG
TH_1635|M.thermoresistible__bu VILGEAMEELDKLTQNFAPRGAEETPAEFARRMVGSAAAVYASNDPVMR-
: .
MMAR_0334|M.marinum_M FIVRERSTGLSVLRYAIRTEIRLITSELATDLARFPGLNEWSTEDLNILA
MUL_4787|M.ulcerans_Agy99 FIVRERSTGLSVLRYAIRTDIRLITSELATDLARFPGLNEWSTEDLNILA
MAV_5169|M.avium_104 LIARERNSGLSVLRYAIRTEIRLITSELATDLARFPGLHEWTTEDLNVLA
MSMEG_1741|M.smegmatis_MC2_155 FIARERSGGASALRYAIRTEIRLITSELAIDLARFPALKDWSSEDLNILA
Mflv_4816|M.gilvum_PYR-GCK FIGRERSTGVTVLRYAIRTEIRLITSELAIDLARFPALNTWSSEDLNILA
Mvan_1626|M.vanbaalenii_PYR-1 FIGRERSTGVTVLRYAIRTEIRLITSELAIDLARFPNLNTWSSEDLNILA
MAB_1424c|M.abscessus_ATCC_199 FLVRERHGGSPQIRRAINNEMRMLTNDVVVELARNPATNHHTTEDLEIAA
Mb1846|M.bovis_AF2122/97 LLYGSPVPGYHAPPDRTAGVATRVVGAFFDAIAAGIATGDIRLTDDVAPQ
Rv1816|M.tuberculosis_H37Rv LLYGSPVPGYHAPPDRTAGVATRVVGAFFDAIAAGIATGDIRLTDDVAPQ
MLBr_00064|M.leprae_Br4923 QVTRDNTEVRKLWSTFMQKWISYTAAVIDAERKRGVAPDTLPATELATAL
TH_1635|M.thermoresistible__bu -ACSAAQNTDAQIREMMGDLQAIVIDKIVGVIEQDASAQPITDDLHALVR
.
MMAR_0334|M.marinum_M TLFVNAMIVTAEAIEDAQSS--EALEEIRRIAVKQLRMVAIGVAGWKSRP
MUL_4787|M.ulcerans_Agy99 TMFVNAMIVTAEAIEDAQSS--EALEEIRRIAVKQLRMVAIGVAGWKSRP
MAV_5169|M.avium_104 TLFVNAMIVIAEAIEDSQSA--EAREDIRRLAVKQLRMIATGIAGWRSTP
MSMEG_1741|M.smegmatis_MC2_155 NLFVNSMISLAEALEDAADA--ESIEAIHRTAVKQMRMIAVGVNGWRSTD
Mflv_4816|M.gilvum_PYR-GCK SVFVNSMIAIAEQLEDVTDT--ASVDEIRRTAVKQLRMITVGVAGWRSG-
Mvan_1626|M.vanbaalenii_PYR-1 SVFVNSMIVIAESLEDATDP--ASIAEIRRIAIKQLRMITVGVAGWRSS-
MAB_1424c|M.abscessus_ATCC_199 ELIASSILNTIGMLVDTDHPTKADADAALNRALRQLDLVTSGLAHTRTMT
Mb1846|M.bovis_AF2122/97 PMSSDFEKIRQEFGFPGDDRVVTKCFLLWAGVVGAISLEVFGQYGADMLT
Rv1816|M.tuberculosis_H37Rv PMSSDFEKIRQEFGFPGDDRVVTKCFLLWAGVVGAISLEVFGQYGADMLT
MLBr_00064|M.leprae_Br4923 NLMNERALFASFTAEQPHVPESRVLDTLVHIWVSSIYNEIR---------
TH_1635|M.thermoresistible__bu TLVATTALTLTHDSAFVGRA--TDISRAVDVVERLWLYSLWGGGNLPER-
:
MMAR_0334|M.marinum_M --------------------
MUL_4787|M.ulcerans_Agy99 --------------------
MAV_5169|M.avium_104 --------------------
MSMEG_1741|M.smegmatis_MC2_155 --------------------
Mflv_4816|M.gilvum_PYR-GCK --------------------
Mvan_1626|M.vanbaalenii_PYR-1 --------------------
MAB_1424c|M.abscessus_ATCC_199 TIIAEPAARPSESSATTAAP
Mb1846|M.bovis_AF2122/97 DPGVVFDAQTRLLVAVLAEH
Rv1816|M.tuberculosis_H37Rv DPGVVFDAQTRLLVAVLAEH
MLBr_00064|M.leprae_Br4923 --------------------
TH_1635|M.thermoresistible__bu --------------------