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VNERTPSSRPHRSSRSRDSPSREERKEATRRAIIAAALKLVHDRSFSALSLREVTREAGIVPAAFYRHFE SMEALGLVLIDESFRTLRDTLRGARAGRLDPNRVIESSVEILIGSVAERREHWRFIVRERSTGLSVLRYA IRTDIRLITSELATDLARFPGLNEWSTEDLNILATMFVNAMIVTAEAIEDAQSSEALEEIRRIAVKQLRM VAIGVAGWKSRP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4787 | - | - | 100% (222) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_2933 | - | 6e-08 | 26.77% (198) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_2639 | - | 8e-07 | 37.84% (74) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3084c | - | 2e-07 | 28.04% (107) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4816 | - | 3e-89 | 74.01% (227) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3058c | - | 2e-07 | 28.04% (107) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00064 | - | 1e-06 | 37.04% (81) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1424c | - | 1e-34 | 40.80% (201) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0334 | - | 1e-118 | 98.65% (222) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5169 | - | 1e-96 | 84.13% (208) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1741 | - | 3e-90 | 75.68% (222) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_1635 | - | 2e-08 | 36.99% (73) | transcriptional regulator, TetR family protein |
| M. vanbaalenii PYR-1 | Mvan_1626 | - | 6e-93 | 78.28% (221) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4787|M.ulcerans_Agy99 ----------------MNERTPSSRPHRS--SRSRD-----SPSREERKE
MMAR_0334|M.marinum_M ----------------MNERTPSSRPHRS--GRSRD-----SPSREERKE
MAV_5169|M.avium_104 -----------------------MRGSGR--ERSRE-----SQSREERKE
MSMEG_1741|M.smegmatis_MC2_155 ----------------MNRRTPSTRTRRSETSRSRD-----TLTREERKE
Mflv_4816|M.gilvum_PYR-GCK MGSRQEISAACGRFHTVNSRTPSSRRGHSSRSRSKDGNSRETLSREERKE
Mvan_1626|M.vanbaalenii_PYR-1 ----------------MNSRTPSSRSGRS-RSREKD-----TLSREERKE
MAB_1424c|M.abscessus_ATCC_199 -----------------------MR-----------------HSRAEKKL
Mb3084c|M.bovis_AF2122/97 ----------------MTSHAADEKQAAP--------------PMRRRGD
Rv3058c|M.tuberculosis_H37Rv ----------------MTSHAADEKQAAP--------------PMRRRGD
TH_1635|M.thermoresistible__bu --------------------VTTDSPARE--------------DRRSRGD
MLBr_00064|M.leprae_Br4923 ---------------MINSTAGQTSQSRS------------RRSTRPSGD
MUL_4787|M.ulcerans_Agy99 ATRRAIIAAALKLVHDRSFSALSLREVTREAGIVPAAFYRHFESMEALGL
MMAR_0334|M.marinum_M ATRRAIIAAALKLVHDRSFSALSLREVTREAGIVPAAFYRHFESMEALGL
MAV_5169|M.avium_104 ATRRAIIAAALKLLQDRSFSSLSLREVTREVGIVPAAFYRHFESMESLGL
MSMEG_1741|M.smegmatis_MC2_155 ATRRALIAAALKLLKDHSFSALSLREVTREAGIVPAAFYRHFDSMDALGL
Mflv_4816|M.gilvum_PYR-GCK ATRRAIVDAALHLLAERGFSALSLREVTREAGIVPAAFYRHFDSMEALGL
Mvan_1626|M.vanbaalenii_PYR-1 ATRRAIVAAALSLLAERSFSGLSLREVTREAGIVPAAFYRHFESMEALGL
MAB_1424c|M.abscessus_ATCC_199 HTRRTLLDGTLELLKVRGFAAVSLREVAKSAGLVPTAFYRHFESMEDLGT
Mb3084c|M.bovis_AF2122/97 RHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLA
Rv3058c|M.tuberculosis_H37Rv RHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLA
TH_1635|M.thermoresistible__bu RQRDAIVAAVRELLEERSFADLSVSTISERAGVARSGFYFYFDSKYAVLA
MLBr_00064|M.leprae_Br4923 DRELAILATAEQLLEDRPLTEISVDYLAKSAGISRPTFYFYFASKEAVLL
. ::: . *: :: :*: :: .*: . ** :* * :
MUL_4787|M.ulcerans_Agy99 VLIDESFRTLRDTLRGAR--AGRLDPNRVIESSVEILIGSVAERREHWRF
MMAR_0334|M.marinum_M VLIDESFRTLRDTLRGAR--AGRLDPNRVIESSVEILIGSVAERREHWRF
MAV_5169|M.avium_104 VLIDESFRSLRDTLRDAR--AGKLDPNRVIESSVEILVASVADRREHWRL
MSMEG_1741|M.smegmatis_MC2_155 VLIDESFRSLRDMLRGAR--AGKLDPHHVIESSAEILVSSFNERREHWRF
Mflv_4816|M.gilvum_PYR-GCK VLIDESFRSLREMLRGAR--AGKLDPNRVIESSVDILIDGVQQRREHWRF
Mvan_1626|M.vanbaalenii_PYR-1 VLIDESFRALREMLRGAR--AGKLDPNRVIESSVDILIDSVQQRREHWRF
MAB_1424c|M.abscessus_ATCC_199 VLAEESVHALRDTFRQARREAGSDNPAKILR----LMVDRVNEHANNFRF
Mb3084c|M.bovis_AF2122/97 QILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA
Rv3058c|M.tuberculosis_H37Rv QILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA
TH_1635|M.thermoresistible__bu VILGEAMEELDKLTQNFAPRGAEETPAEFARRMVGSAAAVYASNDPVMRA
MLBr_00064|M.leprae_Br4923 TLLDRVFNKANAALETLIK-NRDNKRGNKWRTGINVFFETFGSHKAVT--
: . . . . . ..
MUL_4787|M.ulcerans_Agy99 IVRERSTGLSVLRYAIRTDIRLITSELA--TDLARFPGLNEWSTEDLNIL
MMAR_0334|M.marinum_M IVRERSTGLSVLRYAIRTEIRLITSELA--TDLARFPGLNEWSTEDLNIL
MAV_5169|M.avium_104 IARERNSGLSVLRYAIRTEIRLITSELA--TDLARFPGLHEWTTEDLNVL
MSMEG_1741|M.smegmatis_MC2_155 IARERSGGASALRYAIRTEIRLITSELA--IDLARFPALKDWSSEDLNIL
Mflv_4816|M.gilvum_PYR-GCK IGRERSTGVTVLRYAIRTEIRLITSELA--IDLARFPALNTWSSEDLNIL
Mvan_1626|M.vanbaalenii_PYR-1 IGRERSTGVTVLRYAIRTEIRLITSELA--IDLARFPNLNTWSSEDLNIL
MAB_1424c|M.abscessus_ATCC_199 LVRERHGGSPQIRRAINNEMRMLTNDVV--VELARNPATNHHTTEDLEIA
Mb3084c|M.bovis_AF2122/97 CNAARQSD-MEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTL
Rv3058c|M.tuberculosis_H37Rv CNAARQSD-MEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTL
TH_1635|M.thermoresistible__bu CSAAQNTD-AQIREMMGDLQAIVIDKIVGVIEQDASA---QPITDDLHAL
MLBr_00064|M.leprae_Br4923 CAGQVTRDNTEVRKLWSTFMQKWISYTAAVIDAERKRGVAPDTLPATELA
. :* :
MUL_4787|M.ulcerans_Agy99 ATMFVNAMIVTAEAIEDAQSS--EALEEIRRIAVKQLRMVAIGVAGWKSR
MMAR_0334|M.marinum_M ATLFVNAMIVTAEAIEDAQSS--EALEEIRRIAVKQLRMVAIGVAGWKSR
MAV_5169|M.avium_104 ATLFVNAMIVIAEAIEDSQSA--EAREDIRRLAVKQLRMIATGIAGWRST
MSMEG_1741|M.smegmatis_MC2_155 ANLFVNSMISLAEALEDAADA--ESIEAIHRTAVKQMRMIAVGVNGWRST
Mflv_4816|M.gilvum_PYR-GCK ASVFVNSMIAIAEQLEDVTDT--ASVDEIRRTAVKQLRMITVGVAGWRSG
Mvan_1626|M.vanbaalenii_PYR-1 ASVFVNSMIVIAESLEDATDP--ASIAEIRRIAIKQLRMITVGVAGWRSS
MAB_1424c|M.abscessus_ATCC_199 AELIASSILNTIGMLVDTDHPTKADADAALNRALRQLDLVTSGLAHTRTM
Mb3084c|M.bovis_AF2122/97 VRTLAATTALMLTGDALLVGP---DSDAARRVRVLEQMWLNALWGGGKAP
Rv3058c|M.tuberculosis_H37Rv VRTLAATTALMLTGDALLVGP---DSDAARRVRVLEQMWLNALWGGGKAP
TH_1635|M.thermoresistible__bu VRTLVATTALTLTHDSAFVGR---ATDISRAVDVVERLWLYSLWGGGNLP
MLBr_00064|M.leprae_Br4923 TALNLMNERALFASFTAEQPH----VPESRVLDTLVHIWVSSIYNEIR--
. : .
MUL_4787|M.ulcerans_Agy99 P--------------------
MMAR_0334|M.marinum_M P--------------------
MAV_5169|M.avium_104 P--------------------
MSMEG_1741|M.smegmatis_MC2_155 D--------------------
Mflv_4816|M.gilvum_PYR-GCK ---------------------
Mvan_1626|M.vanbaalenii_PYR-1 ---------------------
MAB_1424c|M.abscessus_ATCC_199 TTIIAEPAARPSESSATTAAP
Mb3084c|M.bovis_AF2122/97 ---------------------
Rv3058c|M.tuberculosis_H37Rv ---------------------
TH_1635|M.thermoresistible__bu ER-------------------
MLBr_00064|M.leprae_Br4923 ---------------------