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MSGTFDGIASAITAITGPLSAGHAVKVLVNGTAGSGKTFVLSRIREALGSAGTPAVNHVPEAAPGPNTGP FVIDDADSLTDRQLETLRAVVENDPAAIIVVAAAPRRNPALRSLFQALERESPAITLGPVNATDIGRMSP LAAPFAEQIAAASGGVLALTAAAVERLGDPDPLQSALRAIDTRVDELLRRLSPMAQAAVLLMSLNPGIGA SDVAAALALPDAADLVDEALASGLIAGPGHVAFAARVHGCAARLLGAARHLDLERSLLRTQLEMGSVSAD LALALVGHGLRDLEVARLLSNWATTESDPLSAADLYRAALTAGAEPDPIRVPLAESLARAGDLAAAAAQA DEVLASTDPAQRTAGVRVAAAIACHNGDSGQAAALYSWLGADMDGLTALSASPVFVGTGQLAKGRKSLED NVGAPPTTSATAQRNAALGVIASVEGRGQEALSLLGQAVTQQPSTSSFIPDSTVALAALTMLHSGDTARA RSILTGAIRADRRHDVFGVRHRLLAAWIAMLSGDLSGAVQWLPGAQVELSRRDRLFAESLRTGIARRHGD TGPLRQHWQASMDALSAYSIDLYTLLPVGELWVAAARLRTLDVMTHHLDRAFAVLAHLGDPIAWSAPLRW AGVHAAILTNSPETLAPHGQALAAGAGSSTYARILATAGRTWLRVLANHVDGEEVDSAARMLADTGLGWD ATRLASQAALHANDPKVAASMLALARDLRSPSAAADGESTPSSAVHSPTSTRLSEREREVAELLLRGLPY RDIGAQLFISAKTVEHHVARIRRRLGAESRSDMFSMLRAILTP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4292 | - | - | 100% (813) | LuxR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4519c | - | 2e-07 | 28.93% (159) | two-component LuxR family response regulator |
| M. abscessus ATCC 19977 | MAB_3907c | - | 1e-06 | 30.88% (136) | LuxR transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0346c | - | 0.0 | 47.14% (804) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_0277 | - | 1e-172 | 44.98% (816) | response regulator receiver protein |
| M. tuberculosis H37Rv | Rv0339c | - | 0.0 | 47.14% (804) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_01753 | - | 5e-05 | 43.75% (48) | putative transcriptional regulator |
| M. marinum M | MMAR_0612 | - | 1e-173 | 45.88% (800) | transcriptional regulatory protein |
| M. avium 104 | MAV_0578 | - | 3e-14 | 23.27% (937) | transcriptional regulator, LuxR family protein |
| M. smegmatis MC2 155 | MSMEG_0691 | - | 0.0 | 46.59% (822) | putative transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_4413 | - | 1e-10 | 25.68% (666) | PUTATIVE putative response regulator receiver protein |
| M. ulcerans Agy99 | MUL_4220 | - | 4e-06 | 27.52% (327) | DNA polymerase III subunit delta' |
| M. vanbaalenii PYR-1 | Mvan_0620 | - | 1e-172 | 44.77% (813) | response regulator receiver protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0277|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0620|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0691|M.smegmatis_MC2_155 --------------------------------------------------
Mb0346c|M.bovis_AF2122/97 --------------------------------------------------
Rv0339c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0612|M.marinum_M --------------------------------------------------
MAB_4292|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0578|M.avium_104 ----------------------------------MIGGELLIGRDSELAA
TH_4413|M.thermoresistible__bu --------------------------------------------------
MLBr_01753|M.leprae_Br4923 MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTDLHRGCTVTLFLGDVEG
MUL_4220|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0277|M.gilvum_PYR-GCK ------------------------MLPAAREAIAAVDADPRAATKSLVTG
Mvan_0620|M.vanbaalenii_PYR-1 -------------MTTPAAPRLSDLPPAAREAVAAMEADPHAPVKLVVVG
MSMEG_0691|M.smegmatis_MC2_155 -------------MANPAPEHAVDLPRAVQEMLAGVPSRP---AKLLVSG
Mb0346c|M.bovis_AF2122/97 -MQHRGCKNRGQAYDASVTDSLTEVPPAARRALLELANAPTVPVKVLITG
Rv0339c|M.tuberculosis_H37Rv -MQHRGCKNRGQAYDASVTDSLTEVPPAARRALLELANAPTVPVKVLITG
MMAR_0612|M.marinum_M --MSEGHASRD---DTSAPPDSAAVPAPARGLIDELASGGATSVKALIGG
MAB_4292|M.abscessus_ATCC_1997 -----------------MSGTFDGIASAITAITGPLSAGH--AVKVLVNG
MAV_0578|M.avium_104 IRRALNGADHHRGVVIAGAAGVGKTWLARAALRRAGASGEQIKWIVGTQS
TH_4413|M.thermoresistible__bu --------------------------------------------------
MLBr_01753|M.leprae_Br4923 LAELSETQPDEAADAIARLDCVVSEAVAAHGGVQQVVQGVRGNFLATFAR
MUL_4220|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0277|M.gilvum_PYR-GCK GIGTGKTTLLAAMRTTFRSAGRQVLSRPPDAGTPGDGAGYALVVDDAHLL
Mvan_0620|M.vanbaalenii_PYR-1 GAGSGKSTVLTAVRAVLRASDRPVRSRPRGGETAED---TVTVVDDAHLL
MSMEG_0691|M.smegmatis_MC2_155 GIGTGKSTVLAAVRATLREAGRTVLTRPP---RPDDDQGAVFVIDDAHHL
Mb0346c|M.bovis_AF2122/97 GIGTGKTTVLAAARDTLRRSGLTVLACPPPDGEPPE---TALVIDDAQLL
Rv0339c|M.tuberculosis_H37Rv GIGTGKTTVLAAARDTLRRSGLTVLACPPPDGEPPE---TALVIDDAQLL
MMAR_0612|M.marinum_M GIGTGKTTVLGTVRDALRRAGVTVRAHPTKDCDPSE---VALVVDDAHLL
MAB_4292|M.abscessus_ATCC_1997 TAGSGKTFVLSRIREALGSAGTPAVNHVPEAAPGPN--TGPFVIDDADSL
MAV_0578|M.avium_104 AQALPLGAFIGLLGDAMSEPLTSVRRVIETFVARQRRGRVVVGVDDAHLL
TH_4413|M.thermoresistible__bu --------------------------------------------------
MLBr_01753|M.leprae_Br4923 ASDATACALDLQLAPIVPVRFRIALHTGEVQISNDDVNNVVFMMVQAAGL
MUL_4220|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0277|M.gilvum_PYR-GCK GDDDLDRLTDLAGDPASTVVIATQALMHRS---------------RLQVL
Mvan_0620|M.vanbaalenii_PYR-1 DRAELDQLTELVTDPTAGVVIATEPLAHHG---------------PLREL
MSMEG_0691|M.smegmatis_MC2_155 ADDEIDCLTERSTDPSSTVVVAAEPLAHRP---------------VLRAL
Mb0346c|M.bovis_AF2122/97 TDTELLRLTERVADSRLTVVAAAEAREHHR---------------ALRAL
Rv0339c|M.tuberculosis_H37Rv TDTELLRLTERVADSRLTVVAAAEAREHHR---------------ALRAL
MMAR_0612|M.marinum_M AEDELLRLAEWVADPRATVVVGAQLHQQHH---------------ALRAL
MAB_4292|M.abscessus_ATCC_1997 TDRQLETLRAVVENDPAAIIVVAAAPRRNP---------------ALRSL
MAV_0578|M.avium_104 DGLSALVVHQLAQSGGVRLVVTVRTGSHQPDAVTALWKDDLLTRLDLEPL
TH_4413|M.thermoresistible__bu --------------------------------------------------
MLBr_01753|M.leprae_Br4923 LDLACGGQTVLSSITGDLVVDGLPADTWLVDLGSHLLRDLARPVRVMQLC
MUL_4220|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0277|M.gilvum_PYR-GCK MTVLARENPEVALRPLTAAQVQEAATSALG-----------ASVGPELTR
Mvan_0620|M.vanbaalenii_PYR-1 VTALEREHAAVALGPLPPVEVSRIAAAALG-----------LPAAPELVR
MSMEG_0691|M.smegmatis_MC2_155 ATALERENPIVALGPMSTAEVGRLLTATLG-----------SPPPPDTVR
Mb0346c|M.bovis_AF2122/97 TMALERDRPRISLGPLPVAEH-----------------------------
Rv0339c|M.tuberculosis_H37Rv TMALERDRPRISLGPLPVAEH-----------------------------
MMAR_0612|M.marinum_M ATAIERERPQISLGPLPVADQ-----------------------------
MAB_4292|M.abscessus_ATCC_1997 FQALERESPAITLGPVNATDIGRMS-----------------PLAAPFAE
MAV_0578|M.avium_104 SAAATREVIESTLGGPVDARCAARFRRLTG-----------GNTLFLRQL
TH_4413|M.thermoresistible__bu -------VVRRSGG------------------------------------
MLBr_01753|M.leprae_Br4923 HRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAAQIKELQELLTEKRLLT
MUL_4220|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0277|M.gilvum_PYR-GCK LLVSVTGGFPFLVSAALSAIPDG---------------------------
Mvan_0620|M.vanbaalenii_PYR-1 ALLSATAGLPFLLRPALAAAGDG---------------------------
MSMEG_0691|M.smegmatis_MC2_155 AVLAVTAGLPFLVRAVATSAAE----------------------------
Mb0346c|M.bovis_AF2122/97 -LRDCTAGLPFLIHAVSARAQA----------------------------
Rv0339c|M.tuberculosis_H37Rv -LRDCTAGLPFLIHAVSARAQA----------------------------
MMAR_0612|M.marinum_M -LRDSTAGVPFLVEAVSRGTGS----------------------------
MAB_4292|M.abscessus_ATCC_1997 QIAAASGGVLALTAAAVERLGDPDP-------------------------
MAV_0578|M.avium_104 LSDQMAAGRMRRVAGVWMWDGDV---------------------------
TH_4413|M.thermoresistible__bu --------------------------------------------------
MLBr_01753|M.leprae_Br4923 LVGPGGVGKTRLALQVVARVADEFSGELSYFDLAPDTDHDIFPITVLDNL
MUL_4220|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0277|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0620|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0691|M.smegmatis_MC2_155 --------------------------------------------------
Mb0346c|M.bovis_AF2122/97 --------------------------------------------------
Rv0339c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0612|M.marinum_M --------------------------------------------------
MAB_4292|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0578|M.avium_104 --------------------------------------------------
TH_4413|M.thermoresistible__bu --------------------------------------------------
MLBr_01753|M.leprae_Br4923 RRCIGDRRMLMVLDNCEYLLDVCANVMTTLLGACPSLTILATSREPIGVA
MUL_4220|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0277|M.gilvum_PYR-GCK ---------------------AQSARQAAHFALIERLARLDGHLLDTLLV
Mvan_0620|M.vanbaalenii_PYR-1 ---------------------VASMRQAARFGLIERLRGFDERLLDTLLV
MSMEG_0691|M.smegmatis_MC2_155 ------------------------PEEAARYALIERVRHLGEQTRDTLLL
Mb0346c|M.bovis_AF2122/97 ------------------------PAQAAKVALIERLRRLDEPTLDTLLM
Rv0339c|M.tuberculosis_H37Rv ------------------------PAQAAKVALIERLRRLDEPTLDTLLM
MMAR_0612|M.marinum_M ------------------------PVPAARFALIERLRRLDEPTLDALLI
MAB_4292|M.abscessus_ATCC_1997 ---------------------LQSALRAIDTRVDELLRRLSPMAQAAVLL
MAV_0578|M.avium_104 -----------------------AVSASLSDTVGRQLGRLTPPLALVVDT
TH_4413|M.thermoresistible__bu -------------------------APGLIALIEERIGLLAEPVGDVVDI
MLBr_01753|M.leprae_Br4923 GEVIWRVSMLSPADEAVELFTERAALVQPGFSVTDGNRQIVTEICQRLDG
MUL_4220|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0277|M.gilvum_PYR-GCK MTLSPGLGP------------DDVAAALRIPADEAVAAVDSARATALIDP
Mvan_0620|M.vanbaalenii_PYR-1 SSLSFDLGP------------DDVAAALRLSSQEALTAVDRARASGLIEP
MSMEG_0691|M.smegmatis_MC2_155 TSLSLDLGP------------DDVAGALRVSGTDASVLVDRARAGGLVEP
Mb0346c|M.bovis_AF2122/97 MSLTHELGV------------SDVAAALGISVTDARGLVDRAHASGLIES
Rv0339c|M.tuberculosis_H37Rv MSLTHELGV------------SDVAAALGISVTDARGLVDRAHASGLIES
MMAR_0612|M.marinum_M MSLTQESGT------------TDVAAALGVSTSDARQLVDRVHASGLVEP
MAB_4292|M.abscessus_ATCC_1997 MSLNPGIGA------------SDVAAALALP--DAADLVDEALASGLIAG
MAV_0578|M.avium_104 LSQCEPLPVD---------LLCDLASREDLVAAEAMGLVTVERTPRALMA
TH_4413|M.thermoresistible__bu LAVGEPVDLG---------LLTRLTDPAAVEEADVRGLIAIEDGDRALVR
MLBr_01753|M.leprae_Br4923 MPLAIELAAARIRTLSLTEIADGLDDRFRLLTGGARTAVRRQQTLRASMD
MUL_4220|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0277|M.gilvum_PYR-GCK AHTSQFLAAVHDGIAQIVGAARHHDVEMAVLDSQLALC---------TLT
Mvan_0620|M.vanbaalenii_PYR-1 AHPLAFQRTLHDAVAQVVGAARHHDIEVSVLLSQLELS---------TLT
MSMEG_0691|M.smegmatis_MC2_155 AYDKRFLRLVHTSVAQIAGTSRHHDIEIALLHSQLEKA---------TLS
Mb0346c|M.bovis_AF2122/97 SHTAAFLQSVHDAIAQIVGNAHHHEVETSLLRSQLDIS---------PVS
Rv0339c|M.tuberculosis_H37Rv SHTAAFLQSVHDAIAQIVGNAHHHEVETSLLRSQLDIS---------PVS
MMAR_0612|M.marinum_M SHPPAFVQLVHEAVVHIVGNTHHHEVETSLLRSQLDIS---------PMS
MAB_4292|M.abscessus_ATCC_1997 PGHVAFAARVHGCAARLLGAARHLDLERSLLRTQLEMG---------SVS
MAV_0578|M.avium_104 RLAHPLFGELRRAGAGEMYLSTIRGRLATRLAQDQDAD--------MQAT
TH_4413|M.thermoresistible__bu -LAHPLYGEVRRRRAAVTRLRRLRGLVADELAQAADADD-------LAQV
MLBr_01753|M.leprae_Br4923 WSYALLTESERALFRRLSAISGTFDLKVAYAVGHDDLEEPDQVFDRLTML
MUL_4220|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0277|M.gilvum_PYR-GCK ADLALRIADHGVRDDRL-ATALTDFAARVPDRPARAARLYRAATDAGTTA
Mvan_0620|M.vanbaalenii_PYR-1 ADLALRLAEHGLRDERL-ATALTDLAGRTRGHPARAARLYRAAAEAGASA
MSMEG_0691|M.smegmatis_MC2_155 PELAVRLAEHGVRDDRL-AAALTDHAVQVRGQPARAARLYRAAARAGSAA
Mb0346c|M.bovis_AF2122/97 AELALRLAEHGLRDERL-ADILTRYAADTRDASVRCARLYRAAVHAGAKG
Rv0339c|M.tuberculosis_H37Rv AELALRLAEHGLRDERL-ADILTRYAADTRDASVRCARLYRAAVHAGAKG
MMAR_0612|M.marinum_M QDLALRLAEHGLHGERL-ATALAGYASAARGEPAQTARLYRAAVAAGATG
MAB_4292|M.abscessus_ATCC_1997 ADLALALVGHGLRDLEV-ARLLSNWATTESD-PLSAADLYRAALTAGAEP
MAV_0578|M.avium_104 VRRALLTLESDLDPQPE-LYLESARHAMTLLDLDLADRLANAAARAGAP-
TH_4413|M.thermoresistible__bu VRRTTLLLDSDRRPDVD-LFVRAARGAARIGDLPLAERLSGAAVRAGATV
MLBr_01753|M.leprae_Br4923 IDKSLVIVEGRQGGSRYRLLETVRQYAMKKLEESNEVDLVLARHRDHYMA
MUL_4220|M.ulcerans_Agy99 ---------------------MSGVFARLVGQGAVESELLAAARSARSDS
* *
Mflv_0277|M.gilvum_PYR-GCK --VRPALADALVLTGDCVTAGRLADDLLTS----QDPDERAAAVRIAASI
Mvan_0620|M.vanbaalenii_PYR-1 --PGVRLADALALTGDCGTAGRLADDLLTA----PDPAERAAAVRIAASV
MSMEG_0691|M.smegmatis_MC2_155 --LNARLADALALSGDCATAGRMADDLLSS----DDPAERAAAVRIAASI
Mb0346c|M.bovis_AF2122/97 --LTVRLADALARTGDCTAAATLADDLLSS----PDATERAAAVRVAASV
Rv0339c|M.tuberculosis_H37Rv --LTVRLADALARTGDCTAAATLADDLLSS----PDATERAAAVRVAASV
MMAR_0612|M.marinum_M --LKSQLADALARTGDCAGAAELADELLGS----ADSAQRAAAVRIAASV
MAB_4292|M.abscessus_ATCC_1997 DPIRVPLAESLARAGDLAAAAAQADEVLAS----TDPAQRTAGVRVAAAI
MAV_0578|M.avium_104 -GAAGVRAMNLVLLGRGEQAEEALRAITDGADG-DASDRHYWATVRAANL
TH_4413|M.thermoresistible__bu -EAAIVHARALTWLGRGDQAETVLAAI-------DVADHTRLAFMRASNM
MLBr_01753|M.leprae_Br4923 LGALLDTPGDIDHEQLVEQVETELDNLRSAFAWSRETGDIAGALQLASSL
MUL_4220|M.ulcerans_Agy99 -------THSSGFDGDMTHAWLITGPPGSG--------RSIAALCFAAAL
. . . *: :
Mflv_0277|M.gilvum_PYR-GCK ALHDGAARQAADLFAWLGPAPDAVVGAAETIAALAVGDAAAVRSTAQGPP
Mvan_0620|M.vanbaalenii_PYR-1 ALHDGGAEQAHSLFEWLGPVPDTVVAAAATIAAVAAGDAAAARSTAQMPA
MSMEG_0691|M.smegmatis_MC2_155 AMHDGSAAQAADLFRWLGPYPDAAVGSAGTVALLAAGDAEAARAALNTEL
Mb0346c|M.bovis_AF2122/97 AVHDGNTGHAAELFGWLGPHPDTMVSSAATIVFAANGDLATARATLRLKD
Rv0339c|M.tuberculosis_H37Rv AVHDGNTGHAAELFGWLGPHPDTMVSSAATIVFAANGDLATARATLRLKD
MMAR_0612|M.marinum_M AAHEGNAGQAAELFGWLGPYPDAVVGSSAAIVLAAVGDLQTARAALDVKD
MAB_4292|M.abscessus_ATCC_1997 ACHNGDSGQAAALYSWLGADMDGLTALSASPVFVGTGQLAKGRKSLEDNV
MAV_0578|M.avium_104 VWMLGRPADAALVLDGLAARPETPAQAAARCAVQACLDAVAARCQLAAER
TH_4413|M.thermoresistible__bu LWALSDPEGAKRLIGQAAAG--MPADQRAHLDAFCAVHAAAMGQPDEVFR
MLBr_01753|M.leprae_Br4923 QPIWFGRGHMYEGLAWFDSIFEHKNIEHLVAPKEVLARAVANKVMLHAIL
MUL_4220|M.ulcerans_Agy99 QCTSDGDPGCGRCRSCLTTMAGTHADVRRVIPEGLSIGVDDMRAIVQIAS
.
Mflv_0277|M.gilvum_PYR-GCK SGPPTAVARSARAITEGLVMTLDQPYPAAIARLSQAIAVDAVHG-VLPDT
Mvan_0620|M.vanbaalenii_PYR-1 PGPPTSTARAASGLAAGLVMTLDQPYPAAVARLSQALGTDLGQAMALPDT
MSMEG_0691|M.smegmatis_MC2_155 SGPPTSAARAARSLAEGLVASLDQPFTTTVARLGQAVTADPHTDSVGPDT
Mb0346c|M.bovis_AF2122/97 AGPPTMAARCARNLAEGLLLTMDQPYPVAMAKLGQAIATEQSLSQVIPDS
Rv0339c|M.tuberculosis_H37Rv AGPPTMAARCARNLAEGLLLTMDQPYPVAMAKLGQAIATEQSLSQVIPDS
MMAR_0612|M.marinum_M TGPPTMAARAARGLADGLLLTMGQPYPVAMAKLGQAIAAEQPITEATPDS
MAB_4292|M.abscessus_ATCC_1997 GAPPTTSATAQRNAALGVIASVEGRGQEALSLLGQAVTQQPSTSSFIPDS
MAV_0578|M.avium_104 ARAALDSESLPD--FHAMMASLALIMAMGALGQVDDLTAVAEQALRRATT
TH_4413|M.thermoresistible__bu HAGAVVVDELPG--IIGAETAWALTLAAGEAGRTAEAVAAADTGYRLTAR
MLBr_01753|M.leprae_Br4923 ASSPPDGSDLVTQAQQALTMAREIGDSAVLARALTACGFSSGYDTEVARP
MUL_4220|M.ulcerans_Agy99 RRPTTG--------------RHQIVLIEDADRLTEGAAN--ALLKVVEEP
.
Mflv_0277|M.gilvum_PYR-GCK PAALVTLAALHGGD-----PVRARSVIGRAVLADSRPD--------RA--
Mvan_0620|M.vanbaalenii_PYR-1 PAALVTLAALHGGD-----PVRARSVVGRAVHTDGQRE--------SE--
MSMEG_0691|M.smegmatis_MC2_155 PAALVALAALHGGD-----SVRARSVIGRAVRTGAPGA--------ENGT
Mb0346c|M.bovis_AF2122/97 PAALVTLAAIHAGD-----PVRARSVIGRAVRAG----------------
Rv0339c|M.tuberculosis_H37Rv PAALVTLAAIHAGD-----PVRARSVIGRAVRAG----------------
MMAR_0612|M.marinum_M PAALVTLAAIHGGD-----PVRARSVIGRAVRSG----------------
MAB_4292|M.abscessus_ATCC_1997 TVALAALTMLHSGD-----TARARSILTGAIRADR---------------
MAV_0578|M.avium_104 SFEASHMRFWFGAV-----YGRACRLTGRIDEFVS---------------
TH_4413|M.thermoresistible__bu FSDAAYTRFTLTDA-----HVTALILAGRIAAAVD---------------
MLBr_01753|M.leprae_Br4923 YFAEAVELARTQGDKWTLSQIRLWGVVGFCVSGDPVALRAAAEAADDLAQ
MUL_4220|M.ulcerans_Agy99 PASTVFLLCAPSVD------------------------------------
Mflv_0277|M.gilvum_PYR-GCK --DATFVTSRHRLLQGWAYMQDGQLAAAAAAIPAD-GDPRLHRRDALWAA
Mvan_0620|M.vanbaalenii_PYR-1 --DATFVTRRHRLLQGWAYMQDGQLHAASAAVRAA-GDPGPHRRDALWAA
MSMEG_0691|M.smegmatis_MC2_155 PPPAPFWAARHRLLLGWVKMLDGQLTAAGADVSAVESGPPLHRRDALWAA
Mb0346c|M.bovis_AF2122/97 --ADPLFQRRHLLLSGWIKMQEGQLPSASADVAAASAGTHLHRRDALWAA
Rv0339c|M.tuberculosis_H37Rv --ADPLFQRRHLLLSGWIKMQEGQLPSASADVAAASAGTHLHRRDALWAA
MMAR_0612|M.marinum_M --TDQVFHQRHLLLSGWIKMQEGQLPSASADVAAACSGAPMHRRDALWAA
MAB_4292|M.abscessus_ATCC_1997 --RHDVFGVRHRLLAAWIAMLSGDLSGAVQWLPGA--QVELSRRDRLFAE
MAV_0578|M.avium_104 --TARRLADSARDVPGLAYANLALLLGNAELARGAAAEAARLVQEALAGA
TH_4413|M.thermoresistible__bu --TATVLDRQVGDLPGGTALLARGVAGRAALAAGRLDDAVAWLRDVVSVL
MLBr_01753|M.leprae_Br4923 EIGDRFVSLQCRLLLSIAQLWQGDMDGAIVRSGEVVAGAEAAHDTVTRTF
MUL_4220|M.ulcerans_Agy99 ---PEDIAVTLRSRCRHVALVTPPTTAIAQVLIDNDGLAAETANWAASVS
.
Mflv_0277|M.gilvum_PYR-GCK ALHTGIARRSGDTGAMQMHWRSAMDVLAESSADLFTVLPLGELWIAASRL
Mvan_0620|M.vanbaalenii_PYR-1 ALQTAVARRSGDSGAMQKHWYSAMEVLAEYSIDVFTVLPLGELWVAAARM
MSMEG_0691|M.smegmatis_MC2_155 ALRTAIARRSGDSGAIQRHWFAAMEVLAEYSIDLYSLLPLGELWVAAARM
Mb0346c|M.bovis_AF2122/97 ALQTAISRRTGDIGALQQHWYAAMEALAEYSLDLFALLPLGELWVAAARM
Rv0339c|M.tuberculosis_H37Rv ALQTAISRRTGDIGALQQHWYAAMEALAEYSLDLFALLPLGELWVAAARM
MMAR_0612|M.marinum_M ALETAIARRSGDAGALQKHWNAAMEVLGEYSLDLFALLPLGELWVAAARN
MAB_4292|M.abscessus_ATCC_1997 SLRTGIARRHGDTGPLRQHWQASMDALSAYSIDLYTLLPVGELWVAAARL
MAV_0578|M.avium_104 QIHEVTSGLRPASY---FALAEAHGRLGHPAQANEAIAGARSCVPPDFLF
TH_4413|M.thermoresistible__bu FSADTAGGFYGFGYRYQHPYATALAVLGHTAAAATALATLDEREFPSWRY
MLBr_01753|M.leprae_Br4923 GLYVQTRALVHRDVSAALVTAGLVVEAAAELSGVYQGIGYAAMVFAALAM
MUL_4220|M.ulcerans_Agy99 GGHVGRARRLATDPEARQRRERALGLVRDAATPARAYAAAEEL-------
Mflv_0277|M.gilvum_PYR-GCK RQVDQVRHSLDEVFGLLAALGDPLLWSIPLHWAGVHAG-------ILANS
Mvan_0620|M.vanbaalenii_PYR-1 RQVERLRHTLDEVFAMLVGLGDPVLWAVPLHWAGVHAG-------ILANS
MSMEG_0691|M.smegmatis_MC2_155 RRIDRLEHPLAEAFGLLDALGKPVLWSMPLHWAGVHAG-------ILANS
Mb0346c|M.bovis_AF2122/97 RQVDQLQHTLDQALTLLDSLGNPALWSNSLHWAGVHAG-------ILANS
Rv0339c|M.tuberculosis_H37Rv RQVDQLQHTLDQALTLLDSLGNPALWSNSLHWAGVHAG-------ILANS
MMAR_0612|M.marinum_M RQVDQLQHTLDQAFSLLNSLGNPVLWSNSLHWAGVHAG-------ILANS
MAB_4292|M.abscessus_ATCC_1997 RTLDVMTHHLDRAFAVLAHLGDPIAWSAPLRWAGVHAA-------ILTNS
MAV_0578|M.avium_104 -----MHTGLALATGWALAAGGQLREAVATAQAAARLA-------RDRGQ
TH_4413|M.thermoresistible__bu -----LDHERTIALAWLRAAQGAVSTSIQRLRAEAESA-------RTAGR
MLBr_01753|M.leprae_Br4923 GDVAAAVEASEACRPHLGADHGLVAIHLELMAAVALARGDVIVARRLADN
MUL_4220|M.ulcerans_Agy99 -----VAAAEAEALALTSDRAEAETEELRTALGAGGTG---------KGT
. .
Mflv_0277|M.gilvum_PYR-GCK PDAVAPHGAALTAAAPHAQFAKALAAAGRTWLRVLADRVDVAEVTAAA--
Mvan_0620|M.vanbaalenii_PYR-1 PDSVAPHGQALTAAAPHSSFARALAAAGRTWLKVLANQVDADEVSSAA--
MSMEG_0691|M.smegmatis_MC2_155 PGAVAPHGQALTAAAGHSPFARALAGAGRTWLRVLANHVDVDEVAAAA--
Mb0346c|M.bovis_AF2122/97 PESVAPHGQALGAMVAHSTLAQALSDAGRTWLRVLAENVDADEVTAAA--
Rv0339c|M.tuberculosis_H37Rv PESVAPHGQALGAMVAHSTLAQALSDAGRTWLRVLAENVDADEVTAAA--
MMAR_0612|M.marinum_M PGAVAPHGQALGAAAAGNALAHALSVAGRTWLRVLADQVDVDEVTVAA--
MAB_4292|M.abscessus_ATCC_1997 PETLAPHGQALAAGAGSSTYARILATAGRTWLRVLANHVDGEEVDSAA--
MAV_0578|M.avium_104 PTHELACIQAAAQWGDAAGAVRARALADALSLPLADAIACHAEALRAG--
TH_4413|M.thermoresistible__bu FAVELLCLQTAVQFGDRTCGPRLHQLEDRVDGPRVAVAARFADALHTG--
MLBr_01753|M.leprae_Br4923 SVSATTGWHQMAALTTRARIAMAQGEPELARADIHAALACGADIQASLGI
MUL_4220|M.ulcerans_Agy99 AGTMRGSAGAIKDLERRQKSRHTRAARDALDRALIDLATYFRDALLVS--
. :
Mflv_0277|M.gilvum_PYR-GCK ------------------RGLALHGHTWDATRLAGQAALQTTDSRAAQAM
Mvan_0620|M.vanbaalenii_PYR-1 ------------------RGLAQYGHTWDATRLAGQAALQTTDPRVSQAM
MSMEG_0691|M.smegmatis_MC2_155 ------------------RGLAQFGLTWDATRLASQAALQTSDARVSQAM
Mb0346c|M.bovis_AF2122/97 ------------------RSLSHVGLTSDATRLAGQAALQTSDARVSGAM
Rv0339c|M.tuberculosis_H37Rv ------------------RSLSHVGLTSDATRLAGQAALQTSDARVSGAM
MMAR_0612|M.marinum_M ------------------RSLSGVGLTSDATRLAGQAALQTADARVSGAM
MAB_4292|M.abscessus_ATCC_1997 ------------------RMLADTGLGWDATRLASQAALHANDPKVAASM
MAV_0578|M.avium_104 ------------------NGEALLTVAAAYRAIG--DAAAAADAAAQASA
TH_4413|M.thermoresistible__bu ------------------DGSGLRSIADEFEDMG--DMVAAADAAAHAAI
MLBr_01753|M.leprae_Br4923 SDSMELLAELISQGDNHRQAGRLFGAASAQREKTGEVRFKVWDAGYESAV
MUL_4220|M.ulcerans_Agy99 ---------------------------------AKADQPRANHPDMADRV
. ..
Mflv_0277|M.gilvum_PYR-GCK LQLA-----RDLKATVA-ASDASVPSSATDTVAPPPAVPQRVSSTQ-LSE
Mvan_0620|M.vanbaalenii_PYR-1 LQLA-----RDLKDAVAGEAPVDLPDGAPPSAAASAGPSGRPAAAH-LSD
MSMEG_0691|M.smegmatis_MC2_155 LQLA-----RDLKQSGA-ADDVSAPETPRAPVATQAGAP--AGSAR-LSD
Mb0346c|M.bovis_AF2122/97 LQLA-----RDLKLGNDFGEPPSGAGDTEPASGTPPAPRQPPAGSP-LSD
Rv0339c|M.tuberculosis_H37Rv LQLA-----RDLKLGNDFGEPPSGAGDTEPASGTPPAPRQPPAGSP-LSD
MMAR_0612|M.marinum_M LQLA-----RDLKLASGFDEPT----DAEPVAGAAPAPRQPPAGSP-LSD
MAB_4292|M.abscessus_ATCC_1997 LALA-----RDLR----------SPSAAADGESTPSSAVHSPTSTR-LSE
MAV_0578|M.avium_104 AFVE-----GQQHQRGRYAAALAGELAEECGGLCTPALR-TPAGLK-LSG
TH_4413|M.thermoresistible__bu AHRR-----RGLRGSALACSAHAQGLAERCGGAHTPALRRAAEDLP-LTD
MLBr_01753|M.leprae_Br4923 AVLRGAMGCKDFDSAWAEGAAMPIDDAITYAQRGRGNRKRPTTGWESLTP
MUL_4220|M.ulcerans_Agy99 AALA-------------------------------------------AHA
Mflv_0277|M.gilvum_PYR-GCK REREVAELLLQGLPYREIGSQLFISAKTVEHHVARIRRRLGAESRSEMLS
Mvan_0620|M.vanbaalenii_PYR-1 REREVAELLLQGLPYRDIGAQLFISAKTVEHHVARIRRRLGAESRSELLS
MSMEG_0691|M.smegmatis_MC2_155 REREVAELLLLGMPYRDIGNQLFISAKTVEHHVARIRRRLGAESRSEMLS
Mb0346c|M.bovis_AF2122/97 REREVAELLLLGMPYRDIGARLFISAKTVEHHVARIRQRLGAGSRSEMLS
Rv0339c|M.tuberculosis_H37Rv REREVAELLLLGMPYRDIGARLFISAKTVEHHVARIRQRLGAGSRSEMLS
MMAR_0612|M.marinum_M REREVAELLLLGMPYRDIGAQLFISAKTVEHHVARIRRRLGAGSRSEMLS
MAB_4292|M.abscessus_ATCC_1997 REREVAELLLRGLPYRDIGAQLFISAKTVEHHVARIRRRLGAESRSDMFS
MAV_0578|M.avium_104 RQRDVIELAVAGLSNRQIAERLVMSVRTVEGHIYRACQRVGAQSRDELAT
TH_4413|M.thermoresistible__bu REREIVLLLGAGLTNREIADTLTLSVRTVENHIYKSMLKTGTSSRDELAA
MLBr_01753|M.leprae_Br4923 AEHNVIRLVSEGLDTKDIAARLFVSVRTVHTHLTRIYSKLGLTSRVQLVQ
MUL_4220|M.ulcerans_Agy99 TPERLLRCIEAVLNCREALSINVKPKFAVDAMVAAIGQQLR---------
. : : :: . :*. : :
Mflv_0277|M.gilvum_PYR-GCK MLRAALDTPASR----------
Mvan_0620|M.vanbaalenii_PYR-1 MLRALTDSPTRS----------
MSMEG_0691|M.smegmatis_MC2_155 MLRAMFSPQG------------
Mb0346c|M.bovis_AF2122/97 MLRAMLAPESLTADERR-----
Rv0339c|M.tuberculosis_H37Rv MLRAMLAPESLTADERR-----
MMAR_0612|M.marinum_M MLRAMLTAPG------------
MAB_4292|M.abscessus_ATCC_1997 MLRAILTP--------------
MAV_0578|M.avium_104 IIRSRPAGRES-----------
TH_4413|M.thermoresistible__bu LLPRSPRPSDPRRAPRSPRRID
MLBr_01753|M.leprae_Br4923 EAARHN----------------
MUL_4220|M.ulcerans_Agy99 ----------------------