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SGVFARLVGQGAVESELLAAARSARSDSTHSSGFDGDMTHAWLITGPPGSGRSIAALCFAAALQCTSDGD PGCGRCRSCLTTMAGTHADVRRVIPEGLSIGVDDMRAIVQIASRRPTTGRHQIVLIEDADRLTEGAANAL LKVVEEPPASTVFLLCAPSVDPEDIAVTLRSRCRHVALVTPPTTAIAQVLIDNDGLAAETANWAASVSGG HVGRARRLATDPEARQRRERALGLVRDAATPARAYAAAEELVAAAEAEALALTSDRAEAETEELRTALGA GGTGKGTAGTMRGSAGAIKDLERRQKSRHTRAARDALDRALIDLATYFRDALLVSAKADQPRANHPDMAD RVAALAAHATPERLLRCIEAVLNCREALSINVKPKFAVDAMVAAIGQQLR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4220 | - | - | 100% (401) | DNA polymerase III subunit delta' |
| M. ulcerans Agy99 | MUL_4315 | dnaZX | 4e-20 | 25.92% (382) | DNA polymerase III subunits gamma and tau |
| M. ulcerans Agy99 | MUL_1751 | - | 9e-05 | 30.00% (120) | recombination factor protein RarA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3668c | - | 0.0 | 85.29% (401) | DNA polymerase III subunit delta' |
| M. gilvum PYR-GCK | Mflv_1396 | - | 0.0 | 82.88% (403) | DNA polymerase III subunit delta' |
| M. tuberculosis H37Rv | Rv3644c | - | 0.0 | 85.29% (401) | DNA polymerase III subunit delta' |
| M. leprae Br4923 | MLBr_00202 | - | 0.0 | 82.92% (404) | DNA polymerase III subunit delta' |
| M. abscessus ATCC 19977 | MAB_0491 | - | 1e-162 | 72.77% (404) | DNA polymerase III subunit delta' |
| M. marinum M | MMAR_5136 | - | 0.0 | 99.75% (401) | hypothetical protein MMAR_5136 |
| M. avium 104 | MAV_0520 | - | 0.0 | 84.75% (387) | DNA polymerase III subunit delta' |
| M. smegmatis MC2 155 | MSMEG_6153 | - | 0.0 | 81.30% (401) | DNA polymerase III subunit delta' |
| M. thermoresistible (build 8) | TH_0617 | - | 8e-28 | 78.38% (74) | POSSIBLE DNA POLYMERASE |
| M. vanbaalenii PYR-1 | Mvan_5394 | - | 0.0 | 82.27% (406) | DNA polymerase III subunit delta' |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1396|M.gilvum_PYR-GCK ----MAGVFSRLVGQDTVEAELIAAARAARGDSVHD---DDPAETGTMTH
Mvan_5394|M.vanbaalenii_PYR-1 ----MTGVFSRLVGQDAVETELTAAARAARGDSPHTSGLDVSGVTGTMTH
TH_0617|M.thermoresistible__bu --------------------------------------------------
MSMEG_6153|M.smegmatis_MC2_155 ----MSGVFSRLVGQHAVEQELVAAAAAARGDSAHS-----GVATGTMTH
Mb3668c|M.bovis_AF2122/97 ----MSGVFTRLVGQQAVEAELLATAKAARRDSAHS-----AGGGGTMTH
Rv3644c|M.tuberculosis_H37Rv ----MSGVFTRLVGQQAVEAELLATAKAARRDSAHS-----AGGGGTMTH
MUL_4220|M.ulcerans_Agy99 ----MSGVFARLVGQGAVESELLAAARSARSDSTHS-----SGFDGDMTH
MMAR_5136|M.marinum_M MSTVMSGVFARLVGQGAVESELLAAARSARSDSTHS-----SGFDGDMTH
MLBr_00202|M.leprae_Br4923 ----MSGVFTRLVGQDAVEAELLAAAKAARSDLVHS-----RPADGTMTH
MAV_0520|M.avium_104 -----------------MKAELLGAARAARGDAGHS-----DAGAGTMTH
MAB_0491|M.abscessus_ATCC_1997 ----MSGVFGRLVDQGAVVSTLSSSALAARGD-----------DAGRMTH
Mflv_1396|M.gilvum_PYR-GCK AWLITGPPGSGRSIAALCFAAALQCTS---EGRPGCGECRACTTTMAGTH
Mvan_5394|M.vanbaalenii_PYR-1 AWLITGPPGSGRSIAALCFAAALQCTS---DGTPGCGECRACATTMAGTH
TH_0617|M.thermoresistible__bu --------------------------------------------------
MSMEG_6153|M.smegmatis_MC2_155 AWLITGPPGSGRSVAALCFAAALQCTS---DGVPGCGECRACTTTMAGTH
Mb3668c|M.bovis_AF2122/97 AWLLTGPPGSGRSVAALCFAAALQCTS---GGEPGCGRCRACTTTLAGTH
Rv3644c|M.tuberculosis_H37Rv AWLLTGPPGSGRSVAALCFAAALQCTS---GGEPGCGRCRACTTTLAGTH
MUL_4220|M.ulcerans_Agy99 AWLITGPPGSGRSIAALCFAAALQCTS---DGDPGCGRCRSCLTTMAGTH
MMAR_5136|M.marinum_M AWLITGPPGSGRSIAALCFAAALQCTS---DGDPGCGRCRSCLTTMAGTH
MLBr_00202|M.leprae_Br4923 AWLITGPPGSGRSVAAVCFAAALQCTADFQDGGPGCGRCRACTTTMAGTH
MAV_0520|M.avium_104 AWLITGPPGSGRSVAALCFAAALQCTA---DGEPGCGRCHACTTTLAGTH
MAB_0491|M.abscessus_ATCC_1997 AWLFTGPPGSGRSVAALCFAAALQCES---EDVAGCGACRPCTTTMAGTH
Mflv_1396|M.gilvum_PYR-GCK ADVRRIIPEGLSIGVDAMRAIVQIASRRPGTGRWQIVVVEDADRLTEGAA
Mvan_5394|M.vanbaalenii_PYR-1 ADVRRIIPEGLSIGVDAMRAIVQIASRRPGTGRWQIVVIEDADRLTEGAA
TH_0617|M.thermoresistible__bu --------------------------------------------------
MSMEG_6153|M.smegmatis_MC2_155 ADVRRIVPEGLSIAVKEMREIVQIASRRPGTGRWQVVVIEDADRLTEGAA
Mb3668c|M.bovis_AF2122/97 ADVRRVIPEGLSIGVDEMRAIVQIAARRPTTGHWQIVVIEDADRLTEGAA
Rv3644c|M.tuberculosis_H37Rv ADVRRVIPEGLSIGVDEMRAIVQIAARRPTTGHWQIVVIEDADRLTEGAA
MUL_4220|M.ulcerans_Agy99 ADVRRVIPEGLSIGVDDMRAIVQIASRRPTTGRHQIVLIEDADRLTEGAA
MMAR_5136|M.marinum_M ADVRRVIPEGLSIGVDDMRAIVQIASRRPTTGRHQIVLIEDADRLTEGAA
MLBr_00202|M.leprae_Br4923 ADVRRVIPDGLSIGVDEMRAIVHEASRRPSTGYWQIVLIEDADRLTEGAA
MAV_0520|M.avium_104 ADVRRVVPEGLSIGVDGMRAIVQIAARRPATGNWQIVVIEDADRLTEGAA
MAB_0491|M.abscessus_ATCC_1997 ADVRRVVPEGLSIGVDEMRAIVQAAWRRPSTGRWLVVLIEDADRLTEGAG
Mflv_1396|M.gilvum_PYR-GCK NALLKVVEEPPPSTVFLLCAPSVDPEDIAITLRSRCRHVALVTPPVEAIA
Mvan_5394|M.vanbaalenii_PYR-1 NALLKVVEEPPPSTVFLLCAPSVDPEDIAITLRSRCRHVALVTPPVDAIA
TH_0617|M.thermoresistible__bu --------------------------------------------------
MSMEG_6153|M.smegmatis_MC2_155 NALLKVVEEPPPSTVFLLCAPSVDPEDIAITLRSRCRHIALTTPSIDAIA
Mb3668c|M.bovis_AF2122/97 NALLKVVEEPPPSTVFLLCAPSVDPEDIAVTLRSRCRHVALVTPSTHAIA
Rv3644c|M.tuberculosis_H37Rv NALLKVVEEPPPSTVFLLCAPSVDPEDIAVTLRSRCRHVALVTPSTHAIA
MUL_4220|M.ulcerans_Agy99 NALLKVVEEPPASTVFLLCAPSVDPEDIAVTLRSRCRHVALVTPPTTAIA
MMAR_5136|M.marinum_M NALLKVVEEPPASTVFLLCAPSVDPEDIAVTLRSRCRHVALVTPPTTAIA
MLBr_00202|M.leprae_Br4923 NALLKVVEEPPSSTVFLLCAPSVAPEDIAVTLRSRCRHVALVTPSHAAIA
MAV_0520|M.avium_104 NALLKVVEEPPPSTVFLLCAPSVDPEDVAITLRSRCRHVALVTPSTEAIA
MAB_0491|M.abscessus_ATCC_1997 NVLLKVVEEPPPRTVFLLCAPSVDPEDISITLRSRCRHVALVTPSVAAIA
Mflv_1396|M.gilvum_PYR-GCK QVLIDADGLSAAEARWAASVSGGHVGRARRLATDDEARERRKRALGLARD
Mvan_5394|M.vanbaalenii_PYR-1 RVLIDSDGLPEKDAEWAAAVSGGHVGRARRLATDERARERRQRALGLARD
TH_0617|M.thermoresistible__bu --------------------------------------------------
MSMEG_6153|M.smegmatis_MC2_155 DVLITGDGLPPEDARWAASVCGGHVGRARRLATDPEARERRKRALGLARD
Mb3668c|M.bovis_AF2122/97 QVLSDGDGLDPDTANWAASVSGGHVGRARRLATDPQARQRRERALGLARD
Rv3644c|M.tuberculosis_H37Rv QVLSDGDGLDPDTANWAASVSGGHVGRARRLATDPQARQRRERALGLARD
MUL_4220|M.ulcerans_Agy99 QVLIDNDGLAAETANWAASVSGGHVGRARRLATDPEARQRRERALGLVRD
MMAR_5136|M.marinum_M QVLIDNDGLAAETANWAASVSGGHVGRARRLATDPEARQRRERALGLVRD
MLBr_00202|M.leprae_Br4923 RVLIDSDGLAADTANWAALVSGGHVGLARRLATDPEAQQRRERAFGLIRD
MAV_0520|M.avium_104 RVLVDSDGLTPETADWAASVSGGHVGRARRLATDPEARQRRERALGLVRD
MAB_0491|M.abscessus_ATCC_1997 QVLVDRDGIDAEQAQWAASVSGGHVGRARRLATDEQARARRLKALGLARE
Mflv_1396|M.gilvum_PYR-GCK AATPSRAYAAAEELVATAEAEAKALTGDRNEAESEELRTALGAGGTGKGT
Mvan_5394|M.vanbaalenii_PYR-1 AATPSRAYAAAEELVATAEAEAKALTEDRNEVEAEELRTALGAGGTGKGT
TH_0617|M.thermoresistible__bu --------------------------------------------------
MSMEG_6153|M.smegmatis_MC2_155 AATPSRAYAAAEEMVAVAEAEAVALTADRNENETEELKTALGAGGTGKGT
Mb3668c|M.bovis_AF2122/97 AATPSRAYAAAEELVAGAEAEALALTAQRIEAETEELRTALGAGGTGKGT
Rv3644c|M.tuberculosis_H37Rv AATPSRAYAAAEELVAGAEAEALALTAQRIEAETEELRTALGAGGTGKGT
MUL_4220|M.ulcerans_Agy99 AATPARAYAAAEELVAAAEAEALALTSDRAEAETEELRTALGAGGTGKGT
MMAR_5136|M.marinum_M AATPARAYAAAEELVAAAEAEALALTSDRAEAETEELRTALGAGGTGKGT
MLBr_00202|M.leprae_Br4923 AVVPSRAYAVAEELVAAAEAEALVLTAERAEAETEELRTALGAGGTGKGT
MAV_0520|M.avium_104 AATPSRAYAAAEELVAAAEAEAVVLTAERAEAETEELRTALGAGGTGKGT
MAB_0491|M.abscessus_ATCC_1997 AATPSRAYAAAEELVTSADAEAKELTAARNEAEEEELKTALGAGGTGKGA
Mflv_1396|M.gilvum_PYR-GCK AGTMRGAAGALKELEKRQKSRQTRASRDALDRALIDLATYFRDALLVSAG
Mvan_5394|M.vanbaalenii_PYR-1 AGTMRGAAGALKELEKRQKSRHTRASRDALDRALIDLATYFRDALLVSSG
TH_0617|M.thermoresistible__bu --------------------------------------MYFRDALLVATG
MSMEG_6153|M.smegmatis_MC2_155 AGTMRGAAGALKELEKRQKSRQTRASRDALDRALIDLATYFRDALLVSSG
Mb3668c|M.bovis_AF2122/97 GAALRGATGAMKDLERRQKSRQTRASRDALDRALIDLATYFRDALLVAAH
Rv3644c|M.tuberculosis_H37Rv GAALRGATGAMKDLERRQKSRQTRASRDALDRALIDLATYFRDALLVAAH
MUL_4220|M.ulcerans_Agy99 AGTMRGSAGAIKDLERRQKSRHTRAARDALDRALIDLATYFRDALLVSAK
MMAR_5136|M.marinum_M AGTMRGSAGAIKDLERRQKSRHTRAARDALDRALIDLATYFRDALLVSAK
MLBr_00202|M.leprae_Br4923 AGALRSVTGAIKDLERRQKSRQTRASRDALDRVLIDLATYFRDALLVSAN
MAV_0520|M.avium_104 AGAMRGAAGAIKDLERRQKSRQTRASRDALDRALIDLATYFRDALMASSG
MAB_0491|M.abscessus_ATCC_1997 ATALRGSAGVLKDLERKQKSRQTRASRDALDRTLIDLATYFRDALVLSFG
******: :
Mflv_1396|M.gilvum_PYR-GCK ATD---VVANHPDMADKVAALAAHAPPDKLLRCIEAVLECREALAVNVKP
Mvan_5394|M.vanbaalenii_PYR-1 ATD---VVANHPDMAEKVAAMAAHASPEKLLRCIEAVLECREALAVNVKP
TH_0617|M.thermoresistible__bu ADG---IRREHPDMADKVAALAAHAPPEKLLRCIEAVLECREALAVNVKP
MSMEG_6153|M.smegmatis_MC2_155 ANT---VTANHPDMAEKVAALAAHAAPDRLLRCIEAVLECREALAVNVKP
Mb3668c|M.bovis_AF2122/97 AGG---VRANHPDMADRVAALAAHAPPERLLRCIEAVLACREALAVNVKP
Rv3644c|M.tuberculosis_H37Rv AGG---VRANHPDMADRVAALAAHAPPERLLRCIEAVLACREALAVNVKP
MUL_4220|M.ulcerans_Agy99 ADQ---PRANHPDMADRVAALAAHATPERLLRCIEAVLNCREALSINVKP
MMAR_5136|M.marinum_M ADQ---PRANHPDMADRVAALAAHATPERLLRCIEAVLNCREALSINVKP
MLBr_00202|M.leprae_Br4923 AGS---VQPNHPDMADRVAVLACHATPERLLRCIEAVLECREALAVNVKP
MAV_0520|M.avium_104 AGA---VRANHPDMAERVAALAAHAPPERLLRCIEAVLECREALAVNVKP
MAB_0491|M.abscessus_ATCC_1997 AAGQGRVALHHPDMADRLGPMVDRVPPEQLLKCIEAVLECREALAVNVKP
* .*****:::. :. :..*::**:****** *****::****
Mflv_1396|M.gilvum_PYR-GCK KFAVDAMVGTVGQALRS--
Mvan_5394|M.vanbaalenii_PYR-1 KFAVDAMVGTVGQALRS--
TH_0617|M.thermoresistible__bu KFAVDAMVATVGQALRG--
MSMEG_6153|M.smegmatis_MC2_155 KFAVDAMVATIGQALRG--
Mb3668c|M.bovis_AF2122/97 KFAVDAMVATIGQELR---
Rv3644c|M.tuberculosis_H37Rv KFAVDAMVATIGQELR---
MUL_4220|M.ulcerans_Agy99 KFAVDAMVAAIGQQLR---
MMAR_5136|M.marinum_M KFAVDAMVAAIGQQLQ---
MLBr_00202|M.leprae_Br4923 KFAVDALVATIGQELRY--
MAV_0520|M.avium_104 KFAVDAMVATIGQQLG---
MAB_0491|M.abscessus_ATCC_1997 KFAIDALVATAGQALRPSE
***:**:*.: ** *