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M. abscessus ATCC 19977 MAB_4519c (-)

annotation: two-component LuxR family response regulator
coordinates: 4601169 - 4601837
length: 222

TGNTDSEQISVMVVDDHPMWRDGVSRDLQAAGLRVVATADGVASSGRIAATVKPDVVLMDMQLTDGDGAQ
ATAAVLSASPHSHILVLSASAEREDVLEAVKAGATGYLVKSASAAELIDAVRATAKGQAVFTPGLAGLVL
GEFRRMSSAPAADADETPRLSDRETEVLRLVAKGLSAKQIATRLSLSHRTVENHVQSTLRKLQLGNRVEL
TRYAIEHGLDE*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_4519c--100% (222)two-component LuxR family response regulator
M. abscessus ATCC 19977MAB_3714c-2e-3440.93% (215) two-component LuxR family response regulator
M. abscessus ATCC 19977MAB_0060-6e-3037.50% (216) nitrate/nitrite response transcriptional regulatory protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0867cnarL1e-3038.07% (218) nitrate/nitrite response transcriptional regulatory protein
M. gilvum PYR-GCKMflv_3579-1e-8475.81% (215) two component LuxR family transcriptional regulator
M. tuberculosis H37RvRv0844cnarL8e-3138.07% (218) nitrate/nitrite response transcriptional regulatory protein
M. leprae Br4923MLBr_02123-9e-1128.40% (169) two-component response regulator
M. marinum MMMAR_3959-3e-8272.02% (218) two-component transcriptional regulatory protein
M. avium 104MAV_4114-7e-8272.35% (217) response regulator receiver domain-containing protein
M. smegmatis MC2 155MSMEG_3240-3e-8575.00% (212) DNA-binding response regulator, LuxR family protein
M. thermoresistible (build 8)TH_3563-2e-8573.73% (217) PUTATIVE DNA-binding response regulator, LuxR family protein
M. ulcerans Agy99MUL_3814-8e-8271.56% (218) two component transcriptional regulatory protein
M. vanbaalenii PYR-1Mvan_2836-2e-8275.83% (211) two component LuxR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb0867c|M.bovis_AF2122/97           MS-NPQPEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAAALEL
Rv0844c|M.tuberculosis_H37Rv        MS-NPQPEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAAALEL
Mflv_3579|M.gilvum_PYR-GCK          -M--GIDRT-SVMVVDDHPIWRDAVARDLADDG-FDVVATADGVASAKRR
Mvan_2836|M.vanbaalenii_PYR-1       -----------MMVVDDHPIWRDAVARDLADDG-FDVVATADGVASAKRR
MSMEG_3240|M.smegmatis_MC2_155      MM--TDAAP-TVMVVDDHPIWRDAVARDLADDG-FDVVATADGVASASRR
TH_3563|M.thermoresistible__bu      MG--EPQQP-TVMVVDDHPIWREAVARDLAEAG-LSVVATADGVAAARRR
MMAR_3959|M.marinum_M               MS--EHESP-TVMVVDDHPIWRDAVARDLSDDG-FAVVATADGVATAQRR
MUL_3814|M.ulcerans_Agy99           MS--EHESP-TVMVVDDHPIWRDAVARDLSDDG-FAVVATADGVATAQRR
MAV_4114|M.avium_104                MT--DDATPTTVMVVDDHPIWRDAVARDLAESG-FAVVATADGVATAQRR
MAB_4519c|M.abscessus_ATCC_199      MTGNTDSEQISVMVVDDHPMWRDGVSRDLQAAG-LRVVATADGVASSGRI
MLBr_02123|M.leprae_Br4923          MD--TGVSSPRVLVVDDDSDVLASLERGLRLSG--FEVSTAIDGAEALRN
                                               ::* **..    .: * *   *    *. * . * : . 

Mb0867c|M.bovis_AF2122/97           IKAHLPDVALLDYRMPGMDGAQVPAAVRSYELPTRVLLISAHDEPAIVYQ
Rv0844c|M.tuberculosis_H37Rv        IKAHLPDVALLDYRMPGMDGAQVAAAVRSYELPTRVLLISAHDEPAIVYQ
Mflv_3579|M.gilvum_PYR-GCK          AAVVRPDVVVMDMRLGDGDGAQATTEVLAVSPSSRILVLSASDERDDVLE
Mvan_2836|M.vanbaalenii_PYR-1       AAVVQPAVVLMDMRLADGDGAQATAEVLAVSPSSRVLVLSASDERDDVLE
MSMEG_3240|M.smegmatis_MC2_155      AAVVRPDVVLMDMRLGDGSGAQATAEVLAVSPRSRVLVLSASDERDDVLQ
TH_3563|M.thermoresistible__bu      AAAVRPDVVLMDMRLPDGDGARATAEVRAVSPDSRVLVLSASEERDDVLE
MMAR_3959|M.marinum_M               AAIVKPDVVVMDMRLADGDGVQATTEVLKVSPATRVLVLSASDEREDVLE
MUL_3814|M.ulcerans_Agy99           AAIVKPDVVVMDMRLADGDGVQATTEVLKVSPATRVLVLSTSDEREDVLE
MAV_4114|M.avium_104                AGVVRPDVVVMDMQLPDGDGAQATAAVLAVSPSSRVLVLSASDERDDVLQ
MAB_4519c|M.abscessus_ATCC_199      AATVKPDVVLMDMQLTDGDGAQATAAVLSASPHSHILVLSASAEREDVLE
MLBr_02123|M.leprae_Br4923          ATETRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVA
                                         * . ::* .:   .*. . : :   .    : ::*:  .      

Mb0867c|M.bovis_AF2122/97           ALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAGEIRQRAA
Rv0844c|M.tuberculosis_H37Rv        ALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAGEIRQRAA
Mflv_3579|M.gilvum_PYR-GCK          AVKAGATGYLVKSASKQELGDAVRATAQGRAVFTPGLAGLVLGEFRRIEQ
Mvan_2836|M.vanbaalenii_PYR-1       AVKAGATGYLVKSASKQELGDAVRATAQGRAVFTPGLAGLVLGEFRRIER
MSMEG_3240|M.smegmatis_MC2_155      AVKAGATGYLVKSASRTELADAVRATAEGRAVFTPGLAGLVLGEYRRIAQ
TH_3563|M.thermoresistible__bu      AVKAGATGYLVKSASKTELVDAVHATAQGRAVFTPGLAGLVLGEYRRISR
MMAR_3959|M.marinum_M               AVKAGATGYLVKSASKAELADAVRATAAGRAVFTPSLAGLVLGEYRRIAQ
MUL_3814|M.ulcerans_Agy99           AVKTGATGYLVKSASKAELADAVRATAAGRAVFTPSLAGLVLGEYRRIAQ
MAV_4114|M.avium_104                AVKAGAAGYLVKSASKAELAQAVTDTAAGRAVFTPSLAGLVLGEYRRIAQ
MAB_4519c|M.abscessus_ATCC_199      AVKAGATGYLVKSASAAELIDAVRATAKGQAVFTPGLAGLVLGEFRRMSS
MLBr_02123|M.leprae_Br4923          GLEAGADDYLVKPFVLAELVARVKALLRRRGATATSSSETIAVGPLEVDI
                                    .:: ** .:*:*     *:   *      : . :..    :     .   

Mb0867c|M.bovis_AF2122/97           P--------VAPVLSAREREVLNRIACGQSIPAIAAELYVAPS-------
Rv0844c|M.tuberculosis_H37Rv        P--------VAPVLSAREREVLNRIACGQSIPAIAAELYVAPS-------
Mflv_3579|M.gilvum_PYR-GCK          S---SPAGADGPTLTERETEILRYVAKGLTAKQIASRLSLSHR-------
Mvan_2836|M.vanbaalenii_PYR-1       D---SPAG---PTLTERETEILRHVAKGLTAKQIASRLSLSHR-------
MSMEG_3240|M.smegmatis_MC2_155      QP--AQEGPATPTLTERETEILRYVAKGLTAKQIAARLSLSHR-------
TH_3563|M.thermoresistible__bu      Q---PGAGPDAPRLTERETEILRYVAKGLTAKQIAAQLSLSHR-------
MMAR_3959|M.marinum_M               T---ADSSQDRPSLTERETEILRYVAKGLSAKQIAEKLSLSHR-------
MUL_3814|M.ulcerans_Agy99           T---ADSSQDRPSLTERETEILRYVAKGLSAKQIAEKLSLSHR-------
MAV_4114|M.avium_104                S---KDDGPTRPRLTDRETEVLRYVAKGLSAKQIAEKLSLSHR-------
MAB_4519c|M.abscessus_ATCC_199      AP--AADADETPRLSDRETEVLRLVAKGLSAKQIATRLSLSHR-------
MLBr_02123|M.leprae_Br4923          PGRRARVNGVDVDLTKREFDLLAVLAEHKTTVLSRAQLLELVWGYDFAAD
                                                 *: ** ::*  :*   :      .*            

Mb0867c|M.bovis_AF2122/97           --TVKTHVQRLYEKLGVSDRAAAVAEAMRQRLLD---
Rv0844c|M.tuberculosis_H37Rv        --TVKTHVQRLYEKLGVSDRAAAVAEAMRQRLLD---
Mflv_3579|M.gilvum_PYR-GCK          --TVENHVQATFRKLQVGNRVELARYAIEHGLDE---
Mvan_2836|M.vanbaalenii_PYR-1       --TVENHVQATFRKLQIGNRVELARYAIEHGLDE---
MSMEG_3240|M.smegmatis_MC2_155      --TVENHVQATFRKLQVANRVELARYAIEHGLDE---
TH_3563|M.thermoresistible__bu      --TVENHVQATFRKLQVANRVELARYAIEHGLDE---
MMAR_3959|M.marinum_M               --TVENHVQATFRKLQVANRVELTRYAIEHGLDK---
MUL_3814|M.ulcerans_Agy99           --TVENHVQATFRKLQLANRVELTRYAIEHGLDK---
MAV_4114|M.avium_104                --TVENHVQATFRKLQVANRVELARYAIEHGLDEEP-
MAB_4519c|M.abscessus_ATCC_199      --TVENHVQSTLRKLQLGNRVELTRYAIEHGLDE---
MLBr_02123|M.leprae_Br4923          TNVVDVFIGYLRRKLEANSGPRLLHTVRGVGFVLRMQ
                                      .*. .:    .**   .       .    :