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TTPAAPRLSDLPPAAREAVAAMEADPHAPVKLVVVGGAGSGKSTVLTAVRAVLRASDRPVRSRPRGGETA EDTVTVVDDAHLLDRAELDQLTELVTDPTAGVVIATEPLAHHGPLRELVTALEREHAAVALGPLPPVEVS RIAAAALGLPAAPELVRALLSATAGLPFLLRPALAAAGDGVASMRQAARFGLIERLRGFDERLLDTLLVS SLSFDLGPDDVAAALRLSSQEALTAVDRARASGLIEPAHPLAFQRTLHDAVAQVVGAARHHDIEVSVLLS QLELSTLTADLALRLAEHGLRDERLATALTDLAGRTRGHPARAARLYRAAAEAGASAPGVRLADALALTG DCGTAGRLADDLLTAPDPAERAAAVRIAASVALHDGGAEQAHSLFEWLGPVPDTVVAAAATIAAVAAGDA AAARSTAQMPAPGPPTSTARAASGLAAGLVMTLDQPYPAAVARLSQALGTDLGQAMALPDTPAALVTLAA LHGGDPVRARSVVGRAVHTDGQRESEDATFVTRRHRLLQGWAYMQDGQLHAASAAVRAAGDPGPHRRDAL WAAALQTAVARRSGDSGAMQKHWYSAMEVLAEYSIDVFTVLPLGELWVAAARMRQVERLRHTLDEVFAML VGLGDPVLWAVPLHWAGVHAGILANSPDSVAPHGQALTAAAPHSSFARALAAAGRTWLKVLANQVDADEV SSAARGLAQYGHTWDATRLAGQAALQTTDPRVSQAMLQLARDLKDAVAGEAPVDLPDGAPPSAAASAGPS GRPAAAHLSDREREVAELLLQGLPYRDIGAQLFISAKTVEHHVARIRRRLGAESRSELLSMLRALTDSPT RS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0620 | - | - | 100% (843) | response regulator receiver protein |
| M. vanbaalenii PYR-1 | Mvan_3871 | - | 5e-16 | 25.00% (860) | regulatory protein, LuxR |
| M. vanbaalenii PYR-1 | Mvan_0243 | - | 3e-14 | 24.13% (891) | regulatory protein, LuxR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0346c | - | 0.0 | 58.67% (830) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_0277 | - | 0.0 | 66.87% (830) | response regulator receiver protein |
| M. tuberculosis H37Rv | Rv0339c | - | 0.0 | 58.67% (830) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_01753 | - | 2e-06 | 25.39% (445) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4292 | - | 1e-172 | 44.77% (813) | LuxR family transcriptional regulator |
| M. marinum M | MMAR_0612 | - | 0.0 | 57.09% (839) | transcriptional regulatory protein |
| M. avium 104 | MAV_2364 | - | 2e-20 | 25.25% (887) | TPR repeat-containing protein |
| M. smegmatis MC2 155 | MSMEG_0691 | - | 0.0 | 63.46% (843) | putative transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_4663 | - | 3e-08 | 25.38% (465) | PUTATIVE putative regulatory protein, LuxR |
| M. ulcerans Agy99 | MUL_2876 | - | 3e-08 | 30.87% (149) | putative regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0346c|M.bovis_AF2122/97 --------------------------------------------------
Rv0339c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0612|M.marinum_M --------------------------------------------------
Mvan_0620|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0277|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0691|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4292|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
MAV_2364|M.avium_104 --------------------------------------------------
TH_4663|M.thermoresistible__bu --------------------------------------------------
MLBr_01753|M.leprae_Br4923 MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTDLHRGCTVTLFLGDVEG
Mb0346c|M.bovis_AF2122/97 --------------------------MQHRGCKNRGQAYDASVTDSLTEV
Rv0339c|M.tuberculosis_H37Rv --------------------------MQHRGCKNRGQAYDASVTDSLTEV
MMAR_0612|M.marinum_M ---------------------------MSEGHASRD---DTSAPPDSAAV
Mvan_0620|M.vanbaalenii_PYR-1 --------------------------------------MTTPAAPRLSDL
Mflv_0277|M.gilvum_PYR-GCK -------------------------------------------------M
MSMEG_0691|M.smegmatis_MC2_155 --------------------------------------MANPAPEHAVDL
MAB_4292|M.abscessus_ATCC_1997 ------------------------------------------MSGTFDGI
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
MAV_2364|M.avium_104 -----------------------MEFRRSLAALNNGEFHGVALVGDGGVG
TH_4663|M.thermoresistible__bu -----------------------------VLVGPAGAGKTELARTVLQHR
MLBr_01753|M.leprae_Br4923 LAELSETQPDEAADAIARLDCVVSEAVAAHGGVQQVVQGVRGNFLATFAR
Mb0346c|M.bovis_AF2122/97 PPAARRALLELANAPTVPVKVLITGGIGTGKTT-----------VLAAAR
Rv0339c|M.tuberculosis_H37Rv PPAARRALLELANAPTVPVKVLITGGIGTGKTT-----------VLAAAR
MMAR_0612|M.marinum_M PAPARGLIDELASGGATSVKALIGGGIGTGKTT-----------VLGTVR
Mvan_0620|M.vanbaalenii_PYR-1 PPAAREAVAAMEADPHAPVKLVVVGGAGSGKST-----------VLTAVR
Mflv_0277|M.gilvum_PYR-GCK LPAAREAIAAVDADPRAATKSLVTGGIGTGKTT-----------LLAAMR
MSMEG_0691|M.smegmatis_MC2_155 PRAVQEMLAGVPSRP---AKLLVSGGIGTGKST-----------VLAAVR
MAB_4292|M.abscessus_ATCC_1997 ASAITAITGPLSAGH--AVKVLVNGTAGSGKTF-----------VLSRIR
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
MAV_2364|M.avium_104 KSTLARMLAKTVESAGRTVRFALGTQTGWAVPL-----------GAFSRA
TH_4663|M.thermoresistible__bu RREQPHTVLHWVAGTASASRIPFGAFSHLVETG-----------GGGEPA
MLBr_01753|M.leprae_Br4923 ASDATACALDLQLAPIVPVRFRIALHTGEVQISNDDVNNVVFMMVQAAGL
Mb0346c|M.bovis_AF2122/97 DTLRRSGLTVLACPPPDGEPPE---TALVIDDAQLLT-------------
Rv0339c|M.tuberculosis_H37Rv DTLRRSGLTVLACPPPDGEPPE---TALVIDDAQLLT-------------
MMAR_0612|M.marinum_M DALRRAGVTVRAHPTKDCDPSE---VALVVDDAHLLA-------------
Mvan_0620|M.vanbaalenii_PYR-1 AVLRASDRPVRSRPRGGETAED---TVTVVDDAHLLD-------------
Mflv_0277|M.gilvum_PYR-GCK TTFRSAGRQVLSRPPDAGTPGDGAGYALVVDDAHLLG-------------
MSMEG_0691|M.smegmatis_MC2_155 ATLREAGRTVLTRPP---RPDDDQGAVFVIDDAHHLA-------------
MAB_4292|M.abscessus_ATCC_1997 EALGSAGTPAVNHVPEAAPGPN--TGPFVIDDADSLT-------------
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
MAV_2364|M.avium_104 VSLGVGHEPAIMLAAAHNTLGQDKNLVVVVDEAQLLD-------------
TH_4663|M.thermoresistible__bu TVLRTARESLCGPVLRDRTRTG---LLLIVDDAHHLD-------------
MLBr_01753|M.leprae_Br4923 LDLACGGQTVLSSITGDLVVDGLPADTWLVDLGSHLLRDLARPVRVMQLC
Mb0346c|M.bovis_AF2122/97 --------------------------------DTELLRLTERVADSRLTV
Rv0339c|M.tuberculosis_H37Rv --------------------------------DTELLRLTERVADSRLTV
MMAR_0612|M.marinum_M --------------------------------EDELLRLAEWVADPRATV
Mvan_0620|M.vanbaalenii_PYR-1 --------------------------------RAELDQLTELVTDPTAGV
Mflv_0277|M.gilvum_PYR-GCK --------------------------------DDDLDRLTDLAGDPASTV
MSMEG_0691|M.smegmatis_MC2_155 --------------------------------DDEIDCLTERSTDPSSTV
MAB_4292|M.abscessus_ATCC_1997 --------------------------------DRQLETLRAVVENDPAAI
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
MAV_2364|M.avium_104 --------------------------------PLSATLVNQLAAGRSARL
TH_4663|M.thermoresistible__bu --------------------------------TLSATLVHQVAVSTPASL
MLBr_01753|M.leprae_Br4923 HRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAAQIKELQELLTEKRLLT
Mb0346c|M.bovis_AF2122/97 VAAAEAREHHRALRALTMALERDRP------------RISLGPLPVAEH-
Rv0339c|M.tuberculosis_H37Rv VAAAEAREHHRALRALTMALERDRP------------RISLGPLPVAEH-
MMAR_0612|M.marinum_M VVGAQLHQQHHALRALATAIERERP------------QISLGPLPVADQ-
Mvan_0620|M.vanbaalenii_PYR-1 VIATEPLAHHGPLRELVTALEREHA------------AVALGPLPPVEVS
Mflv_0277|M.gilvum_PYR-GCK VIATQALMHRSRLQVLMTVLARENP------------EVALRPLTAAQVQ
MSMEG_0691|M.smegmatis_MC2_155 VVAAEPLAHRPVLRALATALERENP------------IVALGPMSTAEVG
MAB_4292|M.abscessus_ATCC_1997 IVVAAAPRRNPALRSLFQALERESP------------AITLGPVNATDIG
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
MAV_2364|M.avium_104 IVTIRS-GEPVLDAVTALLKERLLL------------TVHVDPFTREQTE
TH_4663|M.thermoresistible__bu LLTVRD-GEPVPDAITALWKDDLLA------------RIDIEPFSQAECE
MLBr_01753|M.leprae_Br4923 LVGPGGVGKTRLALQVVARVADEFSGELSYFDLAPDTDHDIFPITVLDNL
Mb0346c|M.bovis_AF2122/97 ------------------LRDCTAGLPFLIHAVSARAQA-----------
Rv0339c|M.tuberculosis_H37Rv ------------------LRDCTAGLPFLIHAVSARAQA-----------
MMAR_0612|M.marinum_M ------------------LRDSTAGVPFLVEAVSRGTGS-----------
Mvan_0620|M.vanbaalenii_PYR-1 RIAAAALGLPAAPELVRALLSATAGLPFLLRPALAAAGDG----------
Mflv_0277|M.gilvum_PYR-GCK EAATSALGASVGPELTRLLVSVTGGFPFLVSAALSAIPDG----------
MSMEG_0691|M.smegmatis_MC2_155 RLLTATLGSPPPPDTVRAVLAVTAGLPFLVRAVATSAAE-----------
MAB_4292|M.abscessus_ATCC_1997 RMS------PLAAPFAEQIAAASGGVLALTAAAVERLGDPDP--------
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
MAV_2364|M.avium_104 LLAGAVLGGPVDTRLVDELFERSAGNLLLLRGFLTAGVESG---------
TH_4663|M.thermoresistible__bu RLLADALGGRVESASAERLYAISEGNPLYLRHLVTGTVASG---------
MLBr_01753|M.leprae_Br4923 RRCIGDRRMLMVLDNCEYLLDVCANVMTTLLGACPSLTILATSREPIGVA
Mb0346c|M.bovis_AF2122/97 ------------------------PAQAAKVALIERLRRLDEPTLDTLLM
Rv0339c|M.tuberculosis_H37Rv ------------------------PAQAAKVALIERLRRLDEPTLDTLLM
MMAR_0612|M.marinum_M ------------------------PVPAARFALIERLRRLDEPTLDALLI
Mvan_0620|M.vanbaalenii_PYR-1 ---------------------VASMRQAARFGLIERLRGFDERLLDTLLV
Mflv_0277|M.gilvum_PYR-GCK ---------------------AQSARQAAHFALIERLARLDGHLLDTLLV
MSMEG_0691|M.smegmatis_MC2_155 ------------------------PEEAARYALIERVRHLGEQTRDTLLL
MAB_4292|M.abscessus_ATCC_1997 ---------------------LQSALRAIDTRVDELLRRLSPMAQAAVLL
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
MAV_2364|M.avium_104 -----------------------ALVHTEQGWQLQGPLRGDRELHDALEY
TH_4663|M.thermoresistible__bu -----------------------ALREVEGIWQLRGEVALTPQLSTLIDQ
MLBr_01753|M.leprae_Br4923 GEVIWRVSMLSPADEAVELFTERAALVQPGFSVTDGNRQIVTEICQRLDG
Mb0346c|M.bovis_AF2122/97 MSLTHELGVSDVAAALGISVTDARGLVDRAHASGLIESSHTAAFLQSVHD
Rv0339c|M.tuberculosis_H37Rv MSLTHELGVSDVAAALGISVTDARGLVDRAHASGLIESSHTAAFLQSVHD
MMAR_0612|M.marinum_M MSLTQESGTTDVAAALGVSTSDARQLVDRVHASGLVEPSHPPAFVQLVHE
Mvan_0620|M.vanbaalenii_PYR-1 SSLSFDLGPDDVAAALRLSSQEALTAVDRARASGLIEPAHPLAFQRTLHD
Mflv_0277|M.gilvum_PYR-GCK MTLSPGLGPDDVAAALRIPADEAVAAVDSARATALIDPAHTSQFLAAVHD
MSMEG_0691|M.smegmatis_MC2_155 TSLSLDLGPDDVAGALRVSGTDASVLVDRARAGGLVEPAYDKRFLRLVHT
MAB_4292|M.abscessus_ATCC_1997 MSLNPGIGASDVAAALALP--DAADLVDEALASGLIAGPGHVAFAARVHG
MUL_2876|M.ulcerans_Agy99 MGFSPR---RAIPERTVGGVIDVVDMPDPPAFPTLADDEHPGWASRPIRE
MAV_2364|M.avium_104 RLQSLSSEEREVVEVLATAELLEWEILRDICDADAMASLERRGLIQLVTD
TH_4663|M.thermoresistible__bu HLSALPDQIRTVLAYLAIEEPLTVADLSDLVSPEAVEAAEAAGAVTVDER
MLBr_01753|M.leprae_Br4923 MPLAIELAAARIRTLSLTEIADGLDDRFRLLTGGARTAVRRQQTLRASMD
:
Mb0346c|M.bovis_AF2122/97 AIAQIVGN-----------------------AHHHEVETSLLRSQLDISP
Rv0339c|M.tuberculosis_H37Rv AIAQIVGN-----------------------AHHHEVETSLLRSQLDISP
MMAR_0612|M.marinum_M AVVHIVGN-----------------------THHHEVETSLLRSQLDISP
Mvan_0620|M.vanbaalenii_PYR-1 AVAQVVGA-----------------------ARHHDIEVSVLLSQLELST
Mflv_0277|M.gilvum_PYR-GCK GIAQIVGA-----------------------ARHHDVEMAVLDSQLALCT
MSMEG_0691|M.smegmatis_MC2_155 SVAQIAGT-----------------------SRHHDIEIALLHSQLEKAT
MAB_4292|M.abscessus_ATCC_1997 CAARLLGA-----------------------ARHLDLERSLLRTQLEMGS
MUL_2876|M.ulcerans_Agy99 SDATRHYR-----------------------EAFGDCNVDPTDDPMAVVA
MAV_2364|M.avium_104 GSHTLVQLNH--------------PMLGEAATRHAGVVRSRQLNGILAKT
TH_4663|M.thermoresistible__bu GADLIVHP----------------------AHPLYTETVRAGLGRLTRRS
MLBr_01753|M.leprae_Br4923 WSYALLTESERALFRRLSAISGTFDLKVAYAVGHDDLEEPDQVFDRLTML
Mb0346c|M.bovis_AF2122/97 VSAELALRLAEHGLRDERLADILTRYAADTRDASVRCARLYR---AAVHA
Rv0339c|M.tuberculosis_H37Rv VSAELALRLAEHGLRDERLADILTRYAADTRDASVRCARLYR---AAVHA
MMAR_0612|M.marinum_M MSQDLALRLAEHGLHGERLATALAGYASAARGEPAQTARLYR---AAVAA
Mvan_0620|M.vanbaalenii_PYR-1 LTADLALRLAEHGLRDERLATALTDLAGRTRGHPARAARLYR---AAAEA
Mflv_0277|M.gilvum_PYR-GCK LTADLALRIADHGVRDDRLATALTDFAARVPDRPARAARLYR---AATDA
MSMEG_0691|M.smegmatis_MC2_155 LSPELAVRLAEHGVRDDRLAAALTDHAVQVRGQPARAARLYR---AAARA
MAB_4292|M.abscessus_ATCC_1997 VSADLALALVGHGLRDLEVARLLSNWATTESD-PLSAADLYR---AALTA
MUL_2876|M.ulcerans_Agy99 EAIDVNAAAVRHALESQGDVHAVN-----ALETLLDLSSLER---EMIED
MAV_2364|M.avium_104 LRKHLRAAGRRSQISDPRGRIQLAQFIMRSDLEPDLDVVIKA---AADAM
TH_4663|M.thermoresistible__bu LRTALVARWSRRPPDNVSDRLRLAALAVNSQTPPPATDLIAT---SWEAM
MLBr_01753|M.leprae_Br4923 IDKSLVIVEGRQGGSRYRLLETVRQYAMKKLEESNEVDLVLARHRDHYMA
: : :
Mb0346c|M.bovis_AF2122/97 GAKG--LTVRLADALARTGDCTAAATLADDLLSSPDATERAAAVRVAASV
Rv0339c|M.tuberculosis_H37Rv GAKG--LTVRLADALARTGDCTAAATLADDLLSSPDATERAAAVRVAASV
MMAR_0612|M.marinum_M GATG--LKSQLADALARTGDCAGAAELADELLGSADSAQRAAAVRIAASV
Mvan_0620|M.vanbaalenii_PYR-1 GASA--PGVRLADALALTGDCGTAGRLADDLLTAPDPAERAAAVRIAASV
Mflv_0277|M.gilvum_PYR-GCK GTTA--VRPALADALVLTGDCVTAGRLADDLLTSQDPDERAAAVRIAASI
MSMEG_0691|M.smegmatis_MC2_155 GSAA--LNARLADALALSGDCATAGRMADDLLSSDDPAERAAAVRIAASI
MAB_4292|M.abscessus_ATCC_1997 GAEPDPIRVPLAESLARAGDLAAAAAQADEVLASTDPAQRTAGVRVAAAI
MUL_2876|M.ulcerans_Agy99 GAAR--RTLALLQVQEALSKLRAVDDVAMIVDRAPRELVESCGFDRAVLF
MAV_2364|M.avium_104 AMSNVVLGEQLATFAVDRGGGLAAALVLAEAVSWQGRGEEADSILLGADV
TH_4663|M.thermoresistible__bu QLGDLLLGEQLARGALGQSDTLAARLPLAHALAWQGRGREADDVLAAVDP
MLBr_01753|M.leprae_Br4923 LGALLDTPGDIDHEQLVEQVETELDNLRSAFAWSRETGDIAGALQLASSL
: : . .
Mb0346c|M.bovis_AF2122/97 AVHDGNTGHAAELFGWLGPHPDTMVSSAATIVFAANGDLATARATLRLKD
Rv0339c|M.tuberculosis_H37Rv AVHDGNTGHAAELFGWLGPHPDTMVSSAATIVFAANGDLATARATLRLKD
MMAR_0612|M.marinum_M AAHEGNAGQAAELFGWLGPYPDAVVGSSAAIVLAAVGDLQTARAALDVKD
Mvan_0620|M.vanbaalenii_PYR-1 ALHDGGAEQAHSLFEWLGPVPDTVVAAAATIAAVAAGDAAAARSTAQMPA
Mflv_0277|M.gilvum_PYR-GCK ALHDGAARQAADLFAWLGPAPDAVVGAAETIAALAVGDAAAVRSTAQGPP
MSMEG_0691|M.smegmatis_MC2_155 AMHDGSAAQAADLFRWLGPYPDAAVGSAGTVALLAAGDAEAARAALNTEL
MAB_4292|M.abscessus_ATCC_1997 ACHNGDSGQAAALYSWLGADMDGLTALSASPVFVGTGQLAKGRKSLEDNV
MUL_2876|M.ulcerans_Agy99 RVHEGRLVMESAYFGEDREGAEKMVAFAQSVAPLLDHMLIET--------
MAV_2364|M.avium_104 DDADEWLIARWGCLRAANLAWGCGDAEGATRVLAEVKQRLATEGSLQLID
TH_4663|M.thermoresistible__bu DRLTEFDIMAWTLPKAANQFWMLSESAEAIALLDRMRTRLHQPAAVTAFD
MLBr_01753|M.leprae_Br4923 QPIWFGRGHMYEGLAWFDSIFEHKNIEHLVAPKEVLARAVANKVMLHAIL
Mb0346c|M.bovis_AF2122/97 AGPPTM----------------AARCARNLAEGLL-LTMDQPYPVAMAKL
Rv0339c|M.tuberculosis_H37Rv AGPPTM----------------AARCARNLAEGLL-LTMDQPYPVAMAKL
MMAR_0612|M.marinum_M TGPPTM----------------AARAARGLADGLL-LTMGQPYPVAMAKL
Mvan_0620|M.vanbaalenii_PYR-1 PGPPTS----------------TARAASGLAAGLV-MTLDQPYPAAVARL
Mflv_0277|M.gilvum_PYR-GCK SGPPTA----------------VARSARAITEGLV-MTLDQPYPAAIARL
MSMEG_0691|M.smegmatis_MC2_155 SGPPTS----------------AARAARSLAEGLV-ASLDQPFTTTVARL
MAB_4292|M.abscessus_ATCC_1997 GAPPTT----------------SATAQRNAALGVI-ASVEGRGQEALSLL
MUL_2876|M.ulcerans_Agy99 --------------------------------------------QMIRRH
MAV_2364|M.avium_104 ALDVSIG---------------FFRGDIARTIELG-PRLCEPDVVPMATV
TH_4663|M.thermoresistible__bu ALAATFA---------------MNAGQPRTALELAGRVLQTPESQDLAVA
MLBr_01753|M.leprae_Br4923 ASSPPDGSDLVTQAQQALTMAREIGDSAVLARALTACGFSSGYDTEVARP
:
Mb0346c|M.bovis_AF2122/97 GQAIATEQSLSQVIPDSPAALVTLAAIHAGDPVRARSVIGRAVRAG----
Rv0339c|M.tuberculosis_H37Rv GQAIATEQSLSQVIPDSPAALVTLAAIHAGDPVRARSVIGRAVRAG----
MMAR_0612|M.marinum_M GQAIAAEQPITEATPDSPAALVTLAAIHGGDPVRARSVIGRAVRSG----
Mvan_0620|M.vanbaalenii_PYR-1 SQALGTDLGQAMALPDTPAALVTLAALHGGDPVRARSVVGRAVHTDGQRE
Mflv_0277|M.gilvum_PYR-GCK SQAIAVDAVHG-VLPDTPAALVTLAALHGGDPVRARSVIGRAVLADSRPD
MSMEG_0691|M.smegmatis_MC2_155 GQAVTADPHTDSVGPDTPAALVALAALHGGDSVRARSVIGRAVRTGAPGA
MAB_4292|M.abscessus_ATCC_1997 GQAVTQQPSTSSFIPDSTVALAALTMLHSGDTARARSILTGAIRADR---
MUL_2876|M.ulcerans_Agy99 APAIVRDARNDPRVNRPIVDFSLTHSYVAAPVMPTGKMIG----------
MAV_2364|M.avium_104 WAAVATCGALTAVGRFSEVGRIAAAGVRATAQCRAGAQRFAIGLAEVMAA
TH_4663|M.thermoresistible__bu WAAATATLSSARMARFDEVETHAARGLAAQHPGLLRFTIGLGQITRLILA
MLBr_01753|M.leprae_Br4923 YFAEAVELARTQGDKWTLSQIRLWGVVGFCVSGDPVALRAAAEAADDLAQ
*
Mb0346c|M.bovis_AF2122/97 ------ADPLFQRRHLLLSGWIKMQEGQLPSASADVAAASAGTHLHRRDA
Rv0339c|M.tuberculosis_H37Rv ------ADPLFQRRHLLLSGWIKMQEGQLPSASADVAAASAGTHLHRRDA
MMAR_0612|M.marinum_M ------TDQVFHQRHLLLSGWIKMQEGQLPSASADVAAACSGAPMHRRDA
Mvan_0620|M.vanbaalenii_PYR-1 SE----DATFVTRRHRLLQGWAYMQDGQLHAASAAVRAA-GDPGPHRRDA
Mflv_0277|M.gilvum_PYR-GCK RA----DATFVTSRHRLLQGWAYMQDGQLAAAAAAIPAD-GDPRLHRRDA
MSMEG_0691|M.smegmatis_MC2_155 ENGTPPPAPFWAARHRLLLGWVKMLDGQLTAAGADVSAVESGPPLHRRDA
MAB_4292|M.abscessus_ATCC_1997 ------RHDVFGVRHRLLAAWIAMLSGDLSGAVQWLPGA--QVELSRRDR
MUL_2876|M.ulcerans_Agy99 -----------------FLHADRLYSGRIVDEIDR---------------
MAV_2364|M.avium_104 T-----AAGDYPAAERIHKRYAALATGLPAAEAMVDAMLGVLQLTRGELQ
TH_4663|M.thermoresistible__bu GX--------LTRADFLAHHYLSFCEFQQPGRAIGEVLLAHILIARGDLP
MLBr_01753|M.leprae_Br4923 EIG----DRFVSLQCRLLLSIAQLWQGDMDGAIVRSGEVVAGAEAAHDTV
:
Mb0346c|M.bovis_AF2122/97 LWAAALQTAISRRTGDIGALQQHWYAAMEALAEYSLDLFALLPLGELWVA
Rv0339c|M.tuberculosis_H37Rv LWAAALQTAISRRTGDIGALQQHWYAAMEALAEYSLDLFALLPLGELWVA
MMAR_0612|M.marinum_M LWAAALETAIARRSGDAGALQKHWNAAMEVLGEYSLDLFALLPLGELWVA
Mvan_0620|M.vanbaalenii_PYR-1 LWAAALQTAVARRSGDSGAMQKHWYSAMEVLAEYSIDVFTVLPLGELWVA
Mflv_0277|M.gilvum_PYR-GCK LWAAALHTGIARRSGDTGAMQMHWRSAMDVLAESSADLFTVLPLGELWIA
MSMEG_0691|M.smegmatis_MC2_155 LWAAALRTAIARRSGDSGAIQRHWFAAMEVLAEYSIDLYSLLPLGELWVA
MAB_4292|M.abscessus_ATCC_1997 LFAESLRTGIARRHGDTGPLRQHWQASMDALSAYSIDLYTLLPVGELWVA
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
MAV_2364|M.avium_104 EACATLDRSISQLSQGFPLPWQLVVGALQAQAEGARGDSAAAAVALRRVE
TH_4663|M.thermoresistible__bu TATTLLRQAAAALS-STGYSWGPLALMQLTQVLGARGDADGASEALRRAE
MLBr_01753|M.leprae_Br4923 TRTFGLYVQTRALVHRDVSAALVTAGLVVEAAAELSGVYQGIGYAAMVFA
Mb0346c|M.bovis_AF2122/97 AARMRQVDQLQHTLDQALTLLDSLGNPALWSNSLHWAGVHAG-------I
Rv0339c|M.tuberculosis_H37Rv AARMRQVDQLQHTLDQALTLLDSLGNPALWSNSLHWAGVHAG-------I
MMAR_0612|M.marinum_M AARNRQVDQLQHTLDQAFSLLNSLGNPVLWSNSLHWAGVHAG-------I
Mvan_0620|M.vanbaalenii_PYR-1 AARMRQVERLRHTLDEVFAMLVGLGDPVLWAVPLHWAGVHAG-------I
Mflv_0277|M.gilvum_PYR-GCK ASRLRQVDQVRHSLDEVFGLLAALGDPLLWSIPLHWAGVHAG-------I
MSMEG_0691|M.smegmatis_MC2_155 AARMRRIDRLEHPLAEAFGLLDALGKPVLWSMPLHWAGVHAG-------I
MAB_4292|M.abscessus_ATCC_1997 AARLRTLDVMTHHLDRAFAVLAHLGDPIAWSAPLRWAGVHAA-------I
MUL_2876|M.ulcerans_Agy99 --------------DTVWAFAEGFG----------YAYERTV-------L
MAV_2364|M.avium_104 EAYGPHVAVFLPELELARAWERAAAGDTAG------AQTQAM-------Q
TH_4663|M.thermoresistible__bu HSHGTRSELYAPELALXXXXWRGLRDES--------GHLAAY-------R
MLBr_01753|M.leprae_Br4923 ALAMGDVAAAVEASEACRPHLGADHGLVAIHLELMAAVALARGDVIVARR
. :
Mb0346c|M.bovis_AF2122/97 LANSPESVAPHGQALGAMVAHSTLAQALSDAGRTWLRVLAENVDADEVTA
Rv0339c|M.tuberculosis_H37Rv LANSPESVAPHGQALGAMVAHSTLAQALSDAGRTWLRVLAENVDADEVTA
MMAR_0612|M.marinum_M LANSPGAVAPHGQALGAAAAGNALAHALSVAGRTWLRVLADQVDVDEVTV
Mvan_0620|M.vanbaalenii_PYR-1 LANSPDSVAPHGQALTAAAPHSSFARALAAAGRTWLKVLANQVDADEVSS
Mflv_0277|M.gilvum_PYR-GCK LANSPDAVAPHGAALTAAAPHAQFAKALAAAGRTWLRVLADRVDVAEVTA
MSMEG_0691|M.smegmatis_MC2_155 LANSPGAVAPHGQALTAAAGHSPFARALAGAGRTWLRVLANHVDVDEVAA
MAB_4292|M.abscessus_ATCC_1997 LTNSPETLAPHGQALAAGAGSSTYARILATAGRTWLRVLANHVDGEEVDS
MUL_2876|M.ulcerans_Agy99 LERMRR---QHAEVRSALASADEAARALQDADLDLR-----KIEPVERSP
MAV_2364|M.avium_104 AAQTARKAGMHLVEMRARHAALRFGDRAQAARVDELASILNSPSAQAVAG
TH_4663|M.thermoresistible__bu ITVDDRLPETLADLWDGSAAEVWTAIEFSGTTAHPMITAGCALRSEKKPE
MLBr_01753|M.leprae_Br4923 LADNSVSATTGWHQMAALTTRARIAMAQGEPELARADIHAALACGADIQA
. . .
Mb0346c|M.bovis_AF2122/97 -----------------------AARSLSHVG---LTSDATRLAGQAALQ
Rv0339c|M.tuberculosis_H37Rv -----------------------AARSLSHVG---LTSDATRLAGQAALQ
MMAR_0612|M.marinum_M -----------------------AARSLSGVG---LTSDATRLAGQAALQ
Mvan_0620|M.vanbaalenii_PYR-1 -----------------------AARGLAQYG---HTWDATRLAGQAALQ
Mflv_0277|M.gilvum_PYR-GCK -----------------------AARGLALHG---HTWDATRLAGQAALQ
MSMEG_0691|M.smegmatis_MC2_155 -----------------------AARGLAQFG---LTWDATRLASQAALQ
MAB_4292|M.abscessus_ATCC_1997 -----------------------AARMLADTG---LGWDATRLASQAALH
MUL_2876|M.ulcerans_Agy99 -----------------------AARSLAEVQ---TR-------------
MAV_2364|M.avium_104 -----------------------HARGLAQHDGDLLDAAAHRFADLGALA
TH_4663|M.thermoresistible__bu -----------------------AAGPLPALT------------------
MLBr_01753|M.leprae_Br4923 SLGISDSMELLAELISQGDNHRQAGRLFGAASAQREKTGEVRFKVWDAGY
. :
Mb0346c|M.bovis_AF2122/97 TSDARVSGAMLQLARDLKLGNDFGEPPSGAGDTEPASGTPPAPRQPPAGS
Rv0339c|M.tuberculosis_H37Rv TSDARVSGAMLQLARDLKLGNDFGEPPSGAGDTEPASGTPPAPRQPPAGS
MMAR_0612|M.marinum_M TADARVSGAMLQLARDLKLASGFDEPT----DAEPVAGAAPAPRQPPAGS
Mvan_0620|M.vanbaalenii_PYR-1 TTDPRVSQAMLQLARDLKDAVAGEAPVDLPDGAPPSAAASAGPSGRPAAA
Mflv_0277|M.gilvum_PYR-GCK TTDSRAAQAMLQLARDLKATVA-ASDASVPSSATDTVAPPPAVPQRVSST
MSMEG_0691|M.smegmatis_MC2_155 TSDARVSQAMLQLARDLKQSGA-ADDVSAPETPRAPVATQAGAP--AGSA
MAB_4292|M.abscessus_ATCC_1997 ANDPKVAASMLALARDLR----------SPSAAADGESTPSSAVHSPTST
MUL_2876|M.ulcerans_Agy99 -----------------------------------------------VMA
MAV_2364|M.avium_104 FAADAAAQAASEHARRGDRRKEVESSTWAHALAGQCGSRTPALDAAARPL
TH_4663|M.thermoresistible__bu ------------------------------------PQRGLHRPALEALA
MLBr_01753|M.leprae_Br4923 ESAVAVLRGAMGCKDFDSAWAEGAAMPIDDAITYAQRGRGNRKRPTTGWE
Mb0346c|M.bovis_AF2122/97 PLSDREREVAELLLLGMPYRDIGARLFISAKTVEHHVARIRQRLGAGSRS
Rv0339c|M.tuberculosis_H37Rv PLSDREREVAELLLLGMPYRDIGARLFISAKTVEHHVARIRQRLGAGSRS
MMAR_0612|M.marinum_M PLSDREREVAELLLLGMPYRDIGAQLFISAKTVEHHVARIRRRLGAGSRS
Mvan_0620|M.vanbaalenii_PYR-1 HLSDREREVAELLLQGLPYRDIGAQLFISAKTVEHHVARIRRRLGAESRS
Mflv_0277|M.gilvum_PYR-GCK QLSEREREVAELLLQGLPYREIGSQLFISAKTVEHHVARIRRRLGAESRS
MSMEG_0691|M.smegmatis_MC2_155 RLSDREREVAELLLLGMPYRDIGNQLFISAKTVEHHVARIRRRLGAESRS
MAB_4292|M.abscessus_ATCC_1997 RLSEREREVAELLLRGLPYRDIGAQLFISAKTVEHHVARIRRRLGAESRS
MUL_2876|M.ulcerans_Agy99 MLTRREVEVLRLMAAGRTNQQIADELVISAGTVKSHVKRVLRKLHATNRA
MAV_2364|M.avium_104 PFSGRERQIVNLVAAGLSNREIADRLVISVRTVEGHLYRLFTKLGINNRD
TH_4663|M.thermoresistible__bu PTSGRRLPGEPVPLP----DGLLDSLFWPVRGVRSTARQRRTARQVETES
MLBr_01753|M.leprae_Br4923 SLTPAEHNVIRLVSEGLDTKDIAARLFVSVRTVHTHLTRIYSKLGLTSRV
: . : : *. .. *. : ..
Mb0346c|M.bovis_AF2122/97 EMLSMLRAMLAPESLTADERR
Rv0339c|M.tuberculosis_H37Rv EMLSMLRAMLAPESLTADERR
MMAR_0612|M.marinum_M EMLSMLRAMLTAPG-------
Mvan_0620|M.vanbaalenii_PYR-1 ELLSMLRALTDSPTRS-----
Mflv_0277|M.gilvum_PYR-GCK EMLSMLRAALDTPASR-----
MSMEG_0691|M.smegmatis_MC2_155 EMLSMLRAMFSPQG-------
MAB_4292|M.abscessus_ATCC_1997 DMFSMLRAILTP---------
MUL_2876|M.ulcerans_Agy99 EAASAYVRLASVSEVG-----
MAV_2364|M.avium_104 QLIQLIRRDAS----------
TH_4663|M.thermoresistible__bu VDTAPVSRT------------
MLBr_01753|M.leprae_Br4923 QLVQEAARHN-----------