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M. abscessus ATCC 19977 MAB_3907c (-)

annotation: LuxR transcriptional regulator
coordinates: 3956705 - 3959410
length: 901

TTTTGTIDGRGQAPRLSPAKVHPDLHSYPMARSWQLLDRQTEFGAVRSAMADDSTCGAVLVGAAGVGKTT
LARAVTKSLDADVRWVACTESSRSIPLGVFAHWIQASGSRDPTALIAAARESIVSTANPIIGIDDAHLLD
DLSATLLHQIAVDHVGHVVATVRSGEPVPDAVTALWKDNYLQRFELDPLTQRQSIALVEKVLGGPLEGLS
ADVMWRSSRGNPLFLRHLVEGSMQAGSLTEVNGVWQLRGDAVVPSGLDTLIGDRLEHVDDTVFSALKVLS
MCEPLDIDTLCEIASDEAVDAAEIADLIRVERDGVRTVVRFSHPMFGEAVRRRVGTASGRRLRGKLVRVL
RDRDLGTASNRIRLARLSIDCDEPVDVDLLVTAAKDAVYLSNLPLGEELARAAVDGGGGLQAAAMLSRSL
LWQGRPEQAEEILAAFDPDDLDELSLVLWGIPRISIAFWSMGENERAHELLALLHERVRHHILKPVVDAT
DAAIALHENRFDEGLARAHAVLSDPVAPKQAVEFAAFGVGLTLPVAGRGHEFEPIAQRCRDDKKRTTDGL
IAAMVRYCDVLALTYTGQLDLAEERVAEYTKFSSAGQFLAWAIARIMAGVVATQRGLFREAIEAFEQALA
AQRADRPLPWQLPARLLLARAYAALGRAVDGERVLDEAREHSGPHVAIHMPQMMLAKAWLVAARGSDRGA
VDAARRAADAAHSAGQYALEAEALHHAARFGDRTVGRRIESLCTRVHGPLTGLYARHALAVAHSDITGLE
AVSADFEAAGLLLSAADAAAQAVALRMRAGDRGKGSDAAARVLRMADRCGGVVTPAILAAAKPLPISSRE
REIAVLIGEGLSDKDIATRLQLSVRTVEGHIYRARMKLDADDREEFAKIVGSDLKPPEAS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_3907c--100% (901)LuxR transcriptional regulator
M. abscessus ATCC 19977MAB_4519c-7e-0837.19% (121) two-component LuxR family response regulator
M. abscessus ATCC 19977MAB_4498c-1e-0731.54% (149) two-component LuxR family response regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1236c-5e-7634.16% (565) hypothetical protein Mb1236c
M. gilvum PYR-GCKMflv_4479-1e-15340.19% (841) regulatory protein, LuxR
M. tuberculosis H37RvRv1204c-5e-7634.16% (565) hypothetical protein Rv1204c
M. leprae Br4923MLBr_01753-8e-1022.00% (900) putative transcriptional regulator
M. marinum MMMAR_4234-7e-6131.52% (533) hypothetical protein MMAR_4234
M. avium 104MAV_2362-1e-13535.71% (868) TPR repeat-containing protein
M. smegmatis MC2 155MSMEG_4205-0.063.61% (871) putative transcriptional regulator
M. thermoresistible (build 8)TH_4663-3e-9434.27% (639) PUTATIVE putative regulatory protein, LuxR
M. ulcerans Agy99MUL_0955-4e-6131.52% (533) hypothetical protein MUL_0955
M. vanbaalenii PYR-1Mvan_4065-0.062.49% (861) response regulator receiver protein

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_4205|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4065|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_3907c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2362|M.avium_104                --------------------------------------------------
MMAR_4234|M.marinum_M               --------------------------------------------------
MUL_0955|M.ulcerans_Agy99           --------------------------------------------------
Mb1236c|M.bovis_AF2122/97           --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK          --------------------------------------------------
TH_4663|M.thermoresistible__bu      --------------------------------------------------
MLBr_01753|M.leprae_Br4923          MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTDLHRGCTVTLFLGDVEG
                                                                                      

MSMEG_4205|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4065|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_3907c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2362|M.avium_104                --------------------------------------------------
MMAR_4234|M.marinum_M               --------------------------------------------------
MUL_0955|M.ulcerans_Agy99           --------------------------------------------------
Mb1236c|M.bovis_AF2122/97           --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK          --------------------------------------------------
TH_4663|M.thermoresistible__bu      --------------------------------------------------
MLBr_01753|M.leprae_Br4923          LAELSETQPDEAADAIARLDCVVSEAVAAHGGVQQVVQGVRGNFLATFAR
                                                                                      

MSMEG_4205|M.smegmatis_MC2_155      ---------------------------------MSRQWQLLDRPDEIDAI
Mvan_4065|M.vanbaalenii_PYR-1       ---------------------------------MAPIWQIVDRPAEFGAV
MAB_3907c|M.abscessus_ATCC_199      ---MTTTTGTIDGRGQAPRLSPAKVHPDLHSYPMARSWQLLDRQTEFGAV
MAV_2362|M.avium_104                ----------------------------------------MGREAELRRS
MMAR_4234|M.marinum_M               ---------------------------------MPIRWNVPQHAAALEQL
MUL_0955|M.ulcerans_Agy99           ----------------------------------------------MEQL
Mb1236c|M.bovis_AF2122/97           -------------------------------------------MRVWKHV
Rv1204c|M.tuberculosis_H37Rv        -------------------------------------------MRVWKHV
Mflv_4479|M.gilvum_PYR-GCK          ---------------------------------------MTAGLGLARTQ
TH_4663|M.thermoresistible__bu      --------------------------------------------------
MLBr_01753|M.leprae_Br4923          ASDATACALDLQLAPIVPVRFRIALHTGEVQISNDDVNNVVFMMVQAAGL
                                                                                      

MSMEG_4205|M.smegmatis_MC2_155      RSALESTDTCGVVLVGAAGVG-----------KTTLARTVTSALTNK---
Mvan_4065|M.vanbaalenii_PYR-1       RSALTGNESCGVVLVGDPGVG-----------KTTLARAVAGSLRSQ---
MAB_3907c|M.abscessus_ATCC_199      RSAMADDSTCGAVLVGAAGVG-----------KTTLARAVTKSLDAD---
MAV_2362|M.avium_104                LAALSNAEFHGVALVGDAGVG-----------KSTLARMLAKTVESAGR-
MMAR_4234|M.marinum_M               DVALSDLARPGAVILGPDGVG-----------KSTLARLAAEHFAQRHP-
MUL_0955|M.ulcerans_Agy99           DVALSDLARPGAVILGPDGVG-----------KSTLARLAAEHFAQRHP-
Mb1236c|M.bovis_AF2122/97           EAAVDSPDRCGVVLVGPHGVG-----------KTLLAQLAAEQVMSEDGR
Rv1204c|M.tuberculosis_H37Rv        EAAVDSPDRCGVVLVGPHGVG-----------KTLLAQLAAEQVMSEDGR
Mflv_4479|M.gilvum_PYR-GCK          VESAIVASRLRAVLVGAAGVG-----------KTSMARKLARDYARKHP-
TH_4663|M.thermoresistible__bu      ------------VLVGPAGAG-----------KTELARTVLQHRRREQP-
MLBr_01753|M.leprae_Br4923          LDLACGGQTVLSSITGDLVVDGLPADTWLVDLGSHLLRDLARPVRVMQLC
                                                 : *   ..            : : :            

MSMEG_4205|M.smegmatis_MC2_155      ---VHWTACTESSRSIPLG------------------------AFAHWVG
Mvan_4065|M.vanbaalenii_PYR-1       ---VHWVASTQSSRSIPLG------------------------VFAHLVG
MAB_3907c|M.abscessus_ATCC_199      ---VRWVACTESSRSIPLG------------------------VFAHWIQ
MAV_2362|M.avium_104                --TVRFALGTQTGSAVPLG------------------------AFSHAVS
MMAR_4234|M.marinum_M               ATVIRWVTGTPTERTVPFG------------------------AFSHLVE
MUL_0955|M.ulcerans_Agy99           ATVIRWVTGTPTERAVPLG------------------------AFSHLVE
Mb1236c|M.bovis_AF2122/97           SGRARWVVGTAPGRAIPFG------------------------AFRHLIS
Rv1204c|M.tuberculosis_H37Rv        SGRARWVVGTAPGRAIPFG------------------------AFRHLIS
Mflv_4479|M.gilvum_PYR-GCK          RLTSHWVSATASARDIPFA------------------------AFSHLID
TH_4663|M.thermoresistible__bu      HTVLHWVAGTASASRIPFG------------------------AFSHLVE
MLBr_01753|M.leprae_Br4923          HRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAAQIKELQELLTEKRLLT
                                        :          :* .                        .  : : 

MSMEG_4205|M.smegmatis_MC2_155      AT----ASRDPIALLASARESLVA--------------------------
Mvan_4065|M.vanbaalenii_PYR-1       TS----VSRDATALLASARESLVS--------------------------
MAB_3907c|M.abscessus_ATCC_199      AS----GSRDPTALIAAARESIVS--------------------------
MAV_2362|M.avium_104                LM----AVNEPAVMLAAAHNTLSQ--------------------------
MMAR_4234|M.marinum_M               I----AELGKPAALLRAARASLGRKV------------------------
MUL_0955|M.ulcerans_Agy99           I----AELGKPAALLRAARASLGRKV------------------------
Mb1236c|M.bovis_AF2122/97           LPASGADIGRPAALLRAARSSLTG--------------------------
Rv1204c|M.tuberculosis_H37Rv        LPASGADIGRPAALLRAARSSLTG--------------------------
Mflv_4479|M.gilvum_PYR-GCK          V----SGGEEPTTLLRAARESLR---------------------------
TH_4663|M.thermoresistible__bu      T----GGGGEPATVLRTARESLCGPVLR----------------------
MLBr_01753|M.leprae_Br4923          LVGPGGVGKTRLALQVVARVADEFSGELSYFDLAPDTDHDIFPITVLDNL
                                                .:   *: :                             

MSMEG_4205|M.smegmatis_MC2_155      -----DGDVVVGVDDAHLLDQLSATLLHQFAVDHAGHVVATVRNGEPVPD
Mvan_4065|M.vanbaalenii_PYR-1       -----QGECVVGVDDAHLLDELSATLLHQIAVDQSGRILATVRSGEPVPD
MAB_3907c|M.abscessus_ATCC_199      -----TANPIIGIDDAHLLDDLSATLLHQIAVDHVGHVVATVRSGEPVPD
MAV_2362|M.avium_104                -----DKNLVVVVDDAQLLDPLSATLVNQLAAWRSARLIVTIRSGEPVLD
MMAR_4234|M.marinum_M               ----RQGELLLIVDDAHDLDILSATLVYQLALAGAARMIVTARAEVAP-E
MUL_0955|M.ulcerans_Agy99           ----RQGELLLIVDDAHDLDILSATLVYQLALAGAARMIVTARAEVAP-E
Mb1236c|M.bovis_AF2122/97           ----DAGDLLLVVDDAHNLDPLSATLVYQLARAGAARLVVTVASEAEPPD
Rv1204c|M.tuberculosis_H37Rv        ----DAGDLLLVVDDAHNLDPLSATLVYQLARAGAARLVVTVASEAEPPD
Mflv_4479|M.gilvum_PYR-GCK          ----SAHGLLLVVDDAHHLDTLSATLVHQLAVTDNAHIMLTVREGEPVPD
TH_4663|M.thermoresistible__bu      --DRTRTGLLLIVDDAHHLDTLSATLVHQVAVSTPASLLLTVRDGEPVPD
MLBr_01753|M.leprae_Br4923          RRCIGDRRMLMVLDNCEYLLDVCANVMTTLLG-ACPSLTILATSREPIGV
                                             :: :*:.. *  :.*.::  .       :            

MSMEG_4205|M.smegmatis_MC2_155      AVTSLWKDGYLQRFELQPFSKQQSIALIETVLGGTLEGLSADVMWESSGG
Mvan_4065|M.vanbaalenii_PYR-1       AVTSLWKDGYLRRIELQPFSKEQSVRLVESVVGGRLEGLSADLMWESSGG
MAB_3907c|M.abscessus_ATCC_199      AVTALWKDNYLQRFELDPLTQRQSIALVEKVLGGPLEGLSADVMWRSSRG
MAV_2362|M.avium_104                AVTALLKERLLLTVHVDPFTREQTELLAGTVLGGPVDPWVVDELLQRSSG
MMAR_4234|M.marinum_M               AIAALWTDNLLDRIDVAPPD------------------------------
MUL_0955|M.ulcerans_Agy99           AIAALCTDNLLDRIDVAPPD------------------------------
Mb1236c|M.bovis_AF2122/97           AIAALWSDDLLTRVAIEPLDRAQTAAFVESALDATLDVADADELFRRSLG
Rv1204c|M.tuberculosis_H37Rv        AIAALWSDDLLTRVAIEPLDRAQTAAFVESALDATLDVADADELFRRSLG
Mflv_4479|M.gilvum_PYR-GCK          AVTALWKDSILSRHDIAPFDRRESGLLLEQILGGTVEDVSTVRMFEISQG
TH_4663|M.thermoresistible__bu      AITALWKDDLLARIDIEPFSQAECERLLADALGGRVESASAERLYAISEG
MLBr_01753|M.leprae_Br4923          AGEVIWRVSMLSPADEAVELFTERAALVQPGFSVTDGNRQIVTEICQRLD
                                    *   :     *                                       

MSMEG_4205|M.smegmatis_MC2_155      NPLFLRNMVEGAVDAGTLTEVNGVWQFRGPTVIPSGLAELLDDRLAHAGE
Mvan_4065|M.vanbaalenii_PYR-1       NPLFLRHLVEGSIDAGTLRKVGDVWQLRGPTAVPSGLASLLQDRLDHAGP
MAB_3907c|M.abscessus_ATCC_199      NPLFLRHLVEGSMQAGSLTEVNGVWQLRGDAVVPSGLDTLIGDRLEHVDD
MAV_2362|M.avium_104                NPLLLRGFLTAGRDTGALFRTAEGWQLRGPLRGDRELHDALEYRLQSLSS
MMAR_4234|M.marinum_M               ----------------------------GKTKQS--EPADVDEFIAELPA
MUL_0955|M.ulcerans_Agy99           ----------------------------GQTKQS--EPADVDEFIAELPA
Mb1236c|M.bovis_AF2122/97           NPLYLRHLID----GGGLEHVDGRWRCRDEDRRP--LSGVIDEYLCALPE
Rv1204c|M.tuberculosis_H37Rv        NPLYLRHLID----GGGLEHVDGRWRCRDEDRRP--LSGVIDEYLCALPE
Mflv_4479|M.gilvum_PYR-GCK          NPLYLRHLVDAALGTGSLRQVEGVWQLRGEMTLSPQLTTLIDAHLTNLPE
TH_4663|M.thermoresistible__bu      NPLYLRHLVTGTVASGALREVEGIWQLRGEVALTPQLSTLIDQHLSALPD
MLBr_01753|M.leprae_Br4923          GMPLAIELAAARIRTLSLTEIADG--LDDRFRLLTGGARTAVRRQQTLRA
                                                                .                     

MSMEG_4205|M.smegmatis_MC2_155      DVMNALKLLSLCEPLDIDAFAELAG---EEAVDSAEMRGLIRIVTDAGGT
Mvan_4065|M.vanbaalenii_PYR-1       DVLNALRLLALCEPLDIHALTELAG---DDAVDAAEACDLIRFQQD-GTV
MAB_3907c|M.abscessus_ATCC_199      TVFSALKVLSMCEPLDIDTLCEIAS---DEAVDAAEIADLIRVERD-GVR
MAV_2362|M.avium_104                EEREVVEILATAGLLNWDILRDICD---AEAVAALERRGLIRLVTD-GSH
MMAR_4234|M.marinum_M               PARAVLDYLTVEEPLSLADLTVLAGEGAVQQAVELGAAETRVRGEP-DEP
MUL_0955|M.ulcerans_Agy99           PARAVLDYLTVEEPLSLADLTVLAGEGAVQQAVELGAAETRVRGEP-DEP
Mb1236c|M.bovis_AF2122/97           PARAVVDYLAIAEPLARTDLVALVGGEQLDTLGQAEAAGAVRVGPD-SDT
Rv1204c|M.tuberculosis_H37Rv        PARAVVDYLAIAEPLARTDLVALVGGEQLDTLGQAEAAGAVRVGPD-SDT
Mflv_4479|M.gilvum_PYR-GCK          PVRSVLEFLAIDDPLSVDDLAALTG---IDAVDAAETCGVVTITDR-AGA
TH_4663|M.thermoresistible__bu      QIRTVLAYLAIEEPLTVADLSDLVS---PEAVEAAEAAGAVTVDER-GAD
MLBr_01753|M.leprae_Br4923          SMDWSYALLTESERALFRRLSAISGTFDLKVAYAVGHDDLEEPDQVFDRL
                                            *:         :  : .    .                    

MSMEG_4205|M.smegmatis_MC2_155      LTARFAHPLFAEVVRRRVGTASARKLRGRIAKILRDRD--------LSTA
Mvan_4065|M.vanbaalenii_PYR-1       LNARFSHPLVGDVVRDRIGHATERRLKGQLVELLRRRE--------LSTA
MAB_3907c|M.abscessus_ATCC_199      TVVRFSHPMFGEAVRRRVGTASGRRLRGKLVRVLRDRD--------LGTA
MAV_2362|M.avium_104                AVAQLTHPMLGEAATRHAGMVRTRQLNGKLARALQKHERTGSRHLRLPHL
MMAR_4234|M.marinum_M               AVVYTAHPLFAKRARVALGDDGARQRRTELVTLLSQHP--------NEHL
MUL_0955|M.ulcerans_Agy99           AVVYTAHPLFAKRARVALGDDGARQRRTELVTLLSQHP--------NEHL
Mb1236c|M.bovis_AF2122/97           SEIFVGHPLYADRARAVLTAEHAHALRVSLVAQLAKHP--------SDHV
Rv1204c|M.tuberculosis_H37Rv        SEIFVGHPLYADRARAVLTAEHAHALRVSLVAQLAKHP--------SDHV
Mflv_4479|M.gilvum_PYR-GCK          LYAHPFHPIYTERVRSSLGLLAMRRLRKLLAGRMSVRA--------PGNL
TH_4663|M.thermoresistible__bu      LIVHPAHPLYTETVRAGLGRLTRRSLRTALVARWSRRP--------PDNV
MLBr_01753|M.leprae_Br4923          TMLIDKSLVIVEGRQGGSRYRLLETVRQYAMKKLEESNE-------VDLV
                                            :  .           .  .                       

MSMEG_4205|M.smegmatis_MC2_155      ASRIRLAQLCIESDRGAD---VDLLITAAKDAVFLSNLPLGEQLARAAFD
Mvan_4065|M.vanbaalenii_PYR-1       ASRIRMAQLSIDSDQLLD---IDLLISATKDAIYLFNMPLGQRLAKVAFD
MAB_3907c|M.abscessus_ATCC_199      SNRIRLARLSIDCDEPVD---VDLLVTAAKDAVYLSNLPLGEELARAAVD
MAV_2362|M.avium_104                QSRIRLAEFMLHSDMEPD---LDVITEAARDALAMSNVQLGEELARFALD
MMAR_4234|M.marinum_M               SDRLRLASLALDTDALQP---VDDVVESAEQALRLGDLTLAERLAQAALD
MUL_0955|M.ulcerans_Agy99           SDRLRLASLALDTDALQP---VDDVVESAEQALRLGDLTLAERLAQAALD
Mb1236c|M.bovis_AF2122/97           SDQLRLSSLAIDVPASATPAAVTDAATAAGQALRLGDVRLAERLARAALD
Rv1204c|M.tuberculosis_H37Rv        SDQLRLSSLAIDVPASATPAAVTDAATAAGQALRLGDVRLAERLARAALD
Mflv_4479|M.gilvum_PYR-GCK          STRLRMAALAMGTDEPPS---ADELVGLSWEAMRLGDLALGERLARAALD
TH_4663|M.thermoresistible__bu      SDRLRLAALAVNSQTPPP---ATDLIATSWEAMQLGDLLLGEQLARGALG
MLBr_01753|M.leprae_Br4923          LARHRDHYMALGALLDTPG-DIDHEQLVEQVETELDNLRSAFAWSRETGD
                                      : *   : :                       : ::  .   :: : .

MSMEG_4205|M.smegmatis_MC2_155      HGGGLPAATLLS----------RALLWQGHPAQADNILARFPPDHMDEME
Mvan_4065|M.vanbaalenii_PYR-1       RTGSLEAAELLS----------RTLLWQGRPAAAEAILARFSPDDLDELQ
MAB_3907c|M.abscessus_ATCC_199      GGGGLQAAAMLS----------RSLLWQGRPEQAEEILAAFDPDDLDELS
MAV_2362|M.avium_104                RGGGLPAALVLA----------EAVSWQGRGEEAGFVLAHAEPDGDDDWL
MMAR_4234|M.marinum_M               RSGGLQARLVLG----------QALAWRGRGREAGQVLTAVDPGQLSEAE
MUL_0955|M.ulcerans_Agy99           RSGGLQARLVLG----------QALAWRGRGREAGQVLTAVDPGQLSEAE
Mb1236c|M.bovis_AF2122/97           RSDALAARLPLA----------YALGWQGRGREADAVLAAVNPAELTETE
Rv1204c|M.tuberculosis_H37Rv        RSDALAARLPLA----------YALGWQGRGREADAVLAAVNPAELTETE
Mflv_4479|M.gilvum_PYR-GCK          QADGLAARLPLA----------HSLSWQGRGRDADDVLNPVDPDTLTQWD
TH_4663|M.thermoresistible__bu      QSDTLAARLPLA----------HALAWQGRGREADDVLAAVDPDRLTEFD
MLBr_01753|M.leprae_Br4923          IAGALQLASSLQPIWFGRGHMYEGLAWFDSIFEHKNIEHLVAPKEVLARA
                                      . *     *             : * .       :     *       

MSMEG_4205|M.smegmatis_MC2_155      LVQWGIPRLSILFWSMGDVPLAHQVLGELNSRVTHPILQLIIDATEAG--
Mvan_4065|M.vanbaalenii_PYR-1       LVRWGTPRASHLFWAMGDVERAHEVISLVRERTTHPSLRLFVEAAAAA--
MAB_3907c|M.abscessus_ATCC_199      LVLWGIPRISIAFWSMGENERAHELLALLHERVRHHILKPVVDATDAA--
MAV_2362|M.avium_104                IARWGCLRAANLFWGCGDAEAARREADTVKKRVSSEAGLHLIDALELS--
MMAR_4234|M.marinum_M               LMAWAVPQAANQFWMLGEPERATAFLQTTRNRVTDLTARTTLDALTAT--
MUL_0955|M.ulcerans_Agy99           LMAWAVPQAANQFWMLGEPERATAFLQTTRNRVTDLTARTTLDALTAT--
Mb1236c|M.bovis_AF2122/97           LMAWAIPRAANRFWMLNEPERATAFLQTTRSRVTEPTARSTLDALAAT--
Rv1204c|M.tuberculosis_H37Rv        LMAWAIPRAANRFWMLNEPERATAFLQTTRSRVTEPTARSTLDALAAT--
Mflv_4479|M.gilvum_PYR-GCK          LMAWTLPKAANRFWMLSESEEAVEYLRQMRARITERGALHTIDALAAT--
TH_4663|M.thermoresistible__bu      IMAWTLPKAANQFWMLSESAEAIALLDRMRTRLHQPAAVTAFDALAAT--
MLBr_01753|M.leprae_Br4923          VANKVMLHAILASSPPDGSDLVTQAQQALTMAREIGDSAVLARALTACGF
                                    :      :        .    .                     *      

MSMEG_4205|M.smegmatis_MC2_155      MAVHENRITEGLAIAERVLDHPECPRQATDFAAFACGLAMPVAGRGEAFL
Mvan_4065|M.vanbaalenii_PYR-1       MAVHENRIDEGIAAALQVLDNPLAPGQAVEFAAFAAGLAMPVAGRGDEFE
MAB_3907c|M.abscessus_ATCC_199      IALHENRFDEGLARAHAVLSDPVAPKQAVEFAAFGVGLTLPVAGRGHEFE
MAV_2362|M.avium_104                MAFFRGDVETTTELGPGLCESDAVP-MATTWAAVPTCAALAATGRYSEVG
MMAR_4234|M.marinum_M               FAMNSGNVPRAITLATEVLAEPSADDTAIAWAASAAALASARMGRFADVP
MUL_0955|M.ulcerans_Agy99           FAMNSGNVPRAITLATEVLAEPSADDTAIAWAASAAALASARMGRFADVP
Mb1236c|M.bovis_AF2122/97           FAMNSGNLPRAITLATEVLSGPAADDMAVAWAASAAALSSARMGRFGDVD
Rv1204c|M.tuberculosis_H37Rv        FAMNSGNLPRAITLATEVLSGPAADDMAVAWAASAAALSSARMGRFGDVD
Mflv_4479|M.gilvum_PYR-GCK          FAMNAGDPAEAVTVAKGILAADDAQDLAVAWASAAATLSSARMGRFAEVD
TH_4663|M.thermoresistible__bu      FAMNAGQPRTALELAGRVLQTPESQDLAVAWAAATATLSSARMARFDEVE
MLBr_01753|M.leprae_Br4923          SSGYDTEVARPYFAEAVELARTQGDKWTLSQIRLWGVVGFCVSGDPVALR
                                     :                         :               .    . 

MSMEG_4205|M.smegmatis_MC2_155      PIASRCRAQRK-TTDGMIRIMVFYGEVLALAYTGQFDLARQRAEEYAEFS
Mvan_4065|M.vanbaalenii_PYR-1       PIAARCRADQK-PTDGMIRVMVRYCDVLALTHLGELDLAGRRAAEYADFS
MAB_3907c|M.abscessus_ATCC_199      PIAQRCRDDKKRTTDGLIAAMVRYCDVLALTYTGQLDLAEERVAEYTKFS
MAV_2362|M.avium_104                RIADIGVRAAMSCGMGLHRFNIGISEIIAATDAGD-DRAAERIYKRYAAM
MMAR_4234|M.marinum_M               QLAQRASEAEH---PGLLRFTVGLAQITTLLMAGEVAQAQELAQRFTDFA
MUL_0955|M.ulcerans_Agy99           QLAQRASEAEH---PGLLRFTVGLAQITTLLMAGEVAQAQELAQRFTDFA
Mb1236c|M.bovis_AF2122/97           RLAERASAAEH---PGLLRFTVGLAQITSLLLAGDVAPAQELAKRFTDFA
Rv1204c|M.tuberculosis_H37Rv        RLAERASAAEH---PGLLRFTVGLAQITSLLLAGDVAPAQELAKRFTDFA
Mflv_4479|M.gilvum_PYR-GCK          GLAQRGLDAAH---PGLLRFTLGLGQTLALIMNADVASAEHLARHYLSFS
TH_4663|M.thermoresistible__bu      THAARGLAAQH---PGLLRFTIGLGQITRLILAGXLTRADFLAHHYLSFC
MLBr_01753|M.leprae_Br4923          AAAEAADDLAQEIGDRFVSLQCRLLLSIAQLWQGDMDGAIVRSGEVVAGA
                                      *             :                .    *     .     

MSMEG_4205|M.smegmatis_MC2_155      SAGQFAGWAIAKIMAGAAAMHSGRFRDAISAIEQALAALNAEISLPWQL-
Mvan_4065|M.vanbaalenii_PYR-1       SVGQFLAWAIAKIMAGVVATARGEFPDAVTCIEQALAALNAETSLPWQL-
MAB_3907c|M.abscessus_ATCC_199      SAGQFLAWAIARIMAGVVATQRGLFREAIEAFEQALAAQRADRPLPWQL-
MAV_2362|M.avium_104                AEGLPGAEAMVDAMLGVVRLARGEFPAACAAFTRSISLFAKGFPSPWLV-
MMAR_4234|M.marinum_M               EL-QQPGRAIGEVLLAHVLIVKGEFGAAAAMLEPAAAELERTG-YSWGP-
MUL_0955|M.ulcerans_Agy99           EL-QQPGRAIGEVLLAHVLIVKGEFGTAAAMVEPAAAELERTG-YSWGP-
Mb1236c|M.bovis_AF2122/97           --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK          EF-QQPGRAIGEVLLGHTLLASGRFGDAVTLLRQAAAALTYTG-YSWGP-
TH_4663|M.thermoresistible__bu      EF-QQPGRAIGEVLLAHILIARGDLPTATTLLRQAAAALSSTG-YSWGP-
MLBr_01753|M.leprae_Br4923          EAAHDTVTRTFGLYVQTRALVHRDVSAALVTAGLVVEAAAELSGVYQGIG
                                                                                      

MSMEG_4205|M.smegmatis_MC2_155      -PGRLLLARAYAAVGEVIEAERVLDDAMEHSG----------AFMALHEP
Mvan_4065|M.vanbaalenii_PYR-1       -PGRLLLARAYAALGRTDEAERVLNDAAEHSG----------PSAAIHEP
MAB_3907c|M.abscessus_ATCC_199      -PARLLLARAYAALGRAVDGERVLDEAREHSG----------PHVAIHMP
MAV_2362|M.avium_104                -VVGAFQAQAEGARGDSTAAAAALWRADRAYG----------PHAAVFLP
MMAR_4234|M.marinum_M               -LSLMLLATAIAQQGNIAETAKALRRAETRHG----------TKSALFAP
MUL_0955|M.ulcerans_Agy99           -LSLMLLATAIAQQGNIAETAKALRRAETRHG----------TKSALFAP
Mb1236c|M.bovis_AF2122/97           --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK          -LALTGLAQALGQQGRAADASAVLTRAEASHG----------MRSALYAP
TH_4663|M.thermoresistible__bu      -LALMQLTQVLGARGDADGASEALRRAEHSHG----------TRSELYAP
MLBr_01753|M.leprae_Br4923          YAAMVFAALAMGDVAAAVEASEACRPHLGADHGLVAIHLELMAAVALARG
                                                                                      

MSMEG_4205|M.smegmatis_MC2_155      QRTLAKACVAAAKGAHRSAIDIARSAADLARSSEQHAVEAEALHHCARFG
Mvan_4065|M.vanbaalenii_PYR-1       QRLISRSWYAAAKGMERRALELARAAAEIARQSGQYALEAEALHHATRFG
MAB_3907c|M.abscessus_ATCC_199      QMMLAKAWLVAARGSDRGAVDAARRAADAAHSAGQYALEAEALHHAARFG
MAV_2362|M.avium_104                ELELARAWERAAAGDTQAATTHATQAAEIARAAGMHAAEMRTRHAAVRFG
MMAR_4234|M.marinum_M               ELSLARAWAKATVRDQAGALFDTREAARAAERGKQSAVALCVWHDAVRLG
MUL_0955|M.ulcerans_Agy99           ELSLARAWAKATVRDQAGALFDTREAARAAERGKQSAVALCVWHDAVRLG
Mb1236c|M.bovis_AF2122/97           --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK          DLALARAWTLAAARDLRGAVASARDAVHAAVQSGQDAVALRALQDCARLG
TH_4663|M.thermoresistible__bu      ELALX-XXXWRGLRDESGHLAAYRITVDDRLP-----ETLADLWD----G
MLBr_01753|M.leprae_Br4923          DVIVARRLADNSVSATTGWHQMAALTTRARIAMAQGEPELARADIHAALA
                                                                                      

MSMEG_4205|M.smegmatis_MC2_155      DRTVARRLQGLVDRVDGPLARLYAQHAAAVAAADPVALDAVSSAFEQAGL
Mvan_4065|M.vanbaalenii_PYR-1       DRSTAPRLAELTGVVHGSVVGLLARHAAAFAAGDAAALDVVSADFESAGL
MAB_3907c|M.abscessus_ATCC_199      DRTVGRRIESLCTRVHGPLTGLYARHALAVAHSDITGLEAVSADFEAAGL
MAV_2362|M.avium_104                DRSQTARLERLARILDTPLAEAAADHARGLTQRDGDLLDAAAQQFADLGA
MMAR_4234|M.marinum_M               DTRALAPVTRLAAEIDCKVGNIVVRHARALADNDAGALASVADELAAIGM
MUL_0955|M.ulcerans_Agy99           DTRALAPVTRLAAEIDCKVGNIVVRHARALANNDAGALASVADELAAIGM
Mb1236c|M.bovis_AF2122/97           --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK          DTHGLATAVRLSDRIGCVTGPLCVAHLRALAAGDGAALDAVSADLETAGL
TH_4663|M.thermoresistible__bu      SAAEVWTAIEFS---GTTAHPMITAG----------------CALRSEKK
MLBr_01753|M.leprae_Br4923          CGADIQASLGISDSMELLAELISQGDNHRQAGRLFGAASAQREKTGEVRF
                                                                                      

MSMEG_4205|M.smegmatis_MC2_155      MLSAADAAAQAVLLHDKAGHRRQSTESAAHALQLAGRCGGAATPAIRAAA
Mvan_4065|M.vanbaalenii_PYR-1       MLSAADAAAQAALLHDSAGDRRRTNESGANALRLAEKCGGATTPAIKAAA
MAB_3907c|M.abscessus_ATCC_199      LLSAADAAAQAVALRMRAGDRGKGSDAAARVLRMADRCGGVVTPAILAAA
MAV_2362|M.avium_104                LACAADAAAQAAGEHARRGDRGKKFESSAWAHALASRY-ELHTPAVEAAA
MMAR_4234|M.marinum_M               HAAAADAAAQAERAGGR---------------------------------
MUL_0955|M.ulcerans_Agy99           HAAAADAAAQAERAGGR---------------------------------
Mb1236c|M.bovis_AF2122/97           --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK          PAAAADAAAQATFAHQRRGDRAGEVASRSRASRLSQVCGAPATPALEQVL
TH_4663|M.thermoresistible__bu      PEAAGPLPALTPQRGLHR--PALEALAPTSGRRLPG--------------
MLBr_01753|M.leprae_Br4923          KVWDAGYESAVAVLRGAMGCKDFDSAWAEGAAMPIDDAITYAQRGRGNRK
                                                                                      

MSMEG_4205|M.smegmatis_MC2_155      RPLP----VTAREREVAALVAQGLLNREIAERLTVSVRTVEGHIYRACIK
Mvan_4065|M.vanbaalenii_PYR-1       RPLP----LTPREREIAELVAAGLSNRHIAEQLVLSVRTVEGHVYRACFK
MAB_3907c|M.abscessus_ATCC_199      KPLP----ISSREREIAVLIGEGLSDKDIATRLQLSVRTVEGHIYRARMK
MAV_2362|M.avium_104                RPLP----FSGRERQIVNLVAAGLSNREIADRLVISVRTVEGHLYRLFTK
MMAR_4234|M.marinum_M               --------------------------------------------------
MUL_0955|M.ulcerans_Agy99           --------------------------------------------------
Mb1236c|M.bovis_AF2122/97           --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK          NPMP----LTGREREVAVMVSQGLTNKAIAQRLSVSVRTVEGHVYRACMK
TH_4663|M.thermoresistible__bu      EPVP----LPDGLLDSLFWPVRGVRSTARQRRTARQVETES---------
MLBr_01753|M.leprae_Br4923          RPTTGWESLTPAEHNVIRLVSEGLDTKDIAARLFVSVRTVHTHLTRIYSK
                                                                                      

MSMEG_4205|M.smegmatis_MC2_155      LGVADRDELARMIWTD----------LTPLEADPR-------
Mvan_4065|M.vanbaalenii_PYR-1       LDVADRDELAKLIRKK----------S---------------
MAB_3907c|M.abscessus_ATCC_199      LDADDREEFAKIVGSD----------LKPPEAS---------
MAV_2362|M.avium_104                LGINSREQLTLLVAREPRGRRELLGHSNPSLGDQDDVHPHAG
MMAR_4234|M.marinum_M               ------------------------------------------
MUL_0955|M.ulcerans_Agy99           ------------------------------------------
Mb1236c|M.bovis_AF2122/97           ------------------------------------------
Rv1204c|M.tuberculosis_H37Rv        ------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK          FGVPDRAALASTVGGMHGREGTA-------------------
TH_4663|M.thermoresistible__bu      ---VDTAPVSRT------------------------------
MLBr_01753|M.leprae_Br4923          LGLTSRVQLVQEAARHN-------------------------