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TTTTGTIDGRGQAPRLSPAKVHPDLHSYPMARSWQLLDRQTEFGAVRSAMADDSTCGAVLVGAAGVGKTT LARAVTKSLDADVRWVACTESSRSIPLGVFAHWIQASGSRDPTALIAAARESIVSTANPIIGIDDAHLLD DLSATLLHQIAVDHVGHVVATVRSGEPVPDAVTALWKDNYLQRFELDPLTQRQSIALVEKVLGGPLEGLS ADVMWRSSRGNPLFLRHLVEGSMQAGSLTEVNGVWQLRGDAVVPSGLDTLIGDRLEHVDDTVFSALKVLS MCEPLDIDTLCEIASDEAVDAAEIADLIRVERDGVRTVVRFSHPMFGEAVRRRVGTASGRRLRGKLVRVL RDRDLGTASNRIRLARLSIDCDEPVDVDLLVTAAKDAVYLSNLPLGEELARAAVDGGGGLQAAAMLSRSL LWQGRPEQAEEILAAFDPDDLDELSLVLWGIPRISIAFWSMGENERAHELLALLHERVRHHILKPVVDAT DAAIALHENRFDEGLARAHAVLSDPVAPKQAVEFAAFGVGLTLPVAGRGHEFEPIAQRCRDDKKRTTDGL IAAMVRYCDVLALTYTGQLDLAEERVAEYTKFSSAGQFLAWAIARIMAGVVATQRGLFREAIEAFEQALA AQRADRPLPWQLPARLLLARAYAALGRAVDGERVLDEAREHSGPHVAIHMPQMMLAKAWLVAARGSDRGA VDAARRAADAAHSAGQYALEAEALHHAARFGDRTVGRRIESLCTRVHGPLTGLYARHALAVAHSDITGLE AVSADFEAAGLLLSAADAAAQAVALRMRAGDRGKGSDAAARVLRMADRCGGVVTPAILAAAKPLPISSRE REIAVLIGEGLSDKDIATRLQLSVRTVEGHIYRARMKLDADDREEFAKIVGSDLKPPEAS*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_3907c | - | - | 100% (901) | LuxR transcriptional regulator |
M. abscessus ATCC 19977 | MAB_4519c | - | 7e-08 | 37.19% (121) | two-component LuxR family response regulator |
M. abscessus ATCC 19977 | MAB_4498c | - | 1e-07 | 31.54% (149) | two-component LuxR family response regulator |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1236c | - | 5e-76 | 34.16% (565) | hypothetical protein Mb1236c |
M. gilvum PYR-GCK | Mflv_4479 | - | 1e-153 | 40.19% (841) | regulatory protein, LuxR |
M. tuberculosis H37Rv | Rv1204c | - | 5e-76 | 34.16% (565) | hypothetical protein Rv1204c |
M. leprae Br4923 | MLBr_01753 | - | 8e-10 | 22.00% (900) | putative transcriptional regulator |
M. marinum M | MMAR_4234 | - | 7e-61 | 31.52% (533) | hypothetical protein MMAR_4234 |
M. avium 104 | MAV_2362 | - | 1e-135 | 35.71% (868) | TPR repeat-containing protein |
M. smegmatis MC2 155 | MSMEG_4205 | - | 0.0 | 63.61% (871) | putative transcriptional regulator |
M. thermoresistible (build 8) | TH_4663 | - | 3e-94 | 34.27% (639) | PUTATIVE putative regulatory protein, LuxR |
M. ulcerans Agy99 | MUL_0955 | - | 4e-61 | 31.52% (533) | hypothetical protein MUL_0955 |
M. vanbaalenii PYR-1 | Mvan_4065 | - | 0.0 | 62.49% (861) | response regulator receiver protein |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_4205|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4065|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3907c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2362|M.avium_104 -------------------------------------------------- MMAR_4234|M.marinum_M -------------------------------------------------- MUL_0955|M.ulcerans_Agy99 -------------------------------------------------- Mb1236c|M.bovis_AF2122/97 -------------------------------------------------- Rv1204c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_4479|M.gilvum_PYR-GCK -------------------------------------------------- TH_4663|M.thermoresistible__bu -------------------------------------------------- MLBr_01753|M.leprae_Br4923 MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTDLHRGCTVTLFLGDVEG MSMEG_4205|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4065|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3907c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_2362|M.avium_104 -------------------------------------------------- MMAR_4234|M.marinum_M -------------------------------------------------- MUL_0955|M.ulcerans_Agy99 -------------------------------------------------- Mb1236c|M.bovis_AF2122/97 -------------------------------------------------- Rv1204c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_4479|M.gilvum_PYR-GCK -------------------------------------------------- TH_4663|M.thermoresistible__bu -------------------------------------------------- MLBr_01753|M.leprae_Br4923 LAELSETQPDEAADAIARLDCVVSEAVAAHGGVQQVVQGVRGNFLATFAR MSMEG_4205|M.smegmatis_MC2_155 ---------------------------------MSRQWQLLDRPDEIDAI Mvan_4065|M.vanbaalenii_PYR-1 ---------------------------------MAPIWQIVDRPAEFGAV MAB_3907c|M.abscessus_ATCC_199 ---MTTTTGTIDGRGQAPRLSPAKVHPDLHSYPMARSWQLLDRQTEFGAV MAV_2362|M.avium_104 ----------------------------------------MGREAELRRS MMAR_4234|M.marinum_M ---------------------------------MPIRWNVPQHAAALEQL MUL_0955|M.ulcerans_Agy99 ----------------------------------------------MEQL Mb1236c|M.bovis_AF2122/97 -------------------------------------------MRVWKHV Rv1204c|M.tuberculosis_H37Rv -------------------------------------------MRVWKHV Mflv_4479|M.gilvum_PYR-GCK ---------------------------------------MTAGLGLARTQ TH_4663|M.thermoresistible__bu -------------------------------------------------- MLBr_01753|M.leprae_Br4923 ASDATACALDLQLAPIVPVRFRIALHTGEVQISNDDVNNVVFMMVQAAGL MSMEG_4205|M.smegmatis_MC2_155 RSALESTDTCGVVLVGAAGVG-----------KTTLARTVTSALTNK--- Mvan_4065|M.vanbaalenii_PYR-1 RSALTGNESCGVVLVGDPGVG-----------KTTLARAVAGSLRSQ--- MAB_3907c|M.abscessus_ATCC_199 RSAMADDSTCGAVLVGAAGVG-----------KTTLARAVTKSLDAD--- MAV_2362|M.avium_104 LAALSNAEFHGVALVGDAGVG-----------KSTLARMLAKTVESAGR- MMAR_4234|M.marinum_M DVALSDLARPGAVILGPDGVG-----------KSTLARLAAEHFAQRHP- MUL_0955|M.ulcerans_Agy99 DVALSDLARPGAVILGPDGVG-----------KSTLARLAAEHFAQRHP- Mb1236c|M.bovis_AF2122/97 EAAVDSPDRCGVVLVGPHGVG-----------KTLLAQLAAEQVMSEDGR Rv1204c|M.tuberculosis_H37Rv EAAVDSPDRCGVVLVGPHGVG-----------KTLLAQLAAEQVMSEDGR Mflv_4479|M.gilvum_PYR-GCK VESAIVASRLRAVLVGAAGVG-----------KTSMARKLARDYARKHP- TH_4663|M.thermoresistible__bu ------------VLVGPAGAG-----------KTELARTVLQHRRREQP- MLBr_01753|M.leprae_Br4923 LDLACGGQTVLSSITGDLVVDGLPADTWLVDLGSHLLRDLARPVRVMQLC : * .. : : : MSMEG_4205|M.smegmatis_MC2_155 ---VHWTACTESSRSIPLG------------------------AFAHWVG Mvan_4065|M.vanbaalenii_PYR-1 ---VHWVASTQSSRSIPLG------------------------VFAHLVG MAB_3907c|M.abscessus_ATCC_199 ---VRWVACTESSRSIPLG------------------------VFAHWIQ MAV_2362|M.avium_104 --TVRFALGTQTGSAVPLG------------------------AFSHAVS MMAR_4234|M.marinum_M ATVIRWVTGTPTERTVPFG------------------------AFSHLVE MUL_0955|M.ulcerans_Agy99 ATVIRWVTGTPTERAVPLG------------------------AFSHLVE Mb1236c|M.bovis_AF2122/97 SGRARWVVGTAPGRAIPFG------------------------AFRHLIS Rv1204c|M.tuberculosis_H37Rv SGRARWVVGTAPGRAIPFG------------------------AFRHLIS Mflv_4479|M.gilvum_PYR-GCK RLTSHWVSATASARDIPFA------------------------AFSHLID TH_4663|M.thermoresistible__bu HTVLHWVAGTASASRIPFG------------------------AFSHLVE MLBr_01753|M.leprae_Br4923 HRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAAQIKELQELLTEKRLLT : :* . . : : MSMEG_4205|M.smegmatis_MC2_155 AT----ASRDPIALLASARESLVA-------------------------- Mvan_4065|M.vanbaalenii_PYR-1 TS----VSRDATALLASARESLVS-------------------------- MAB_3907c|M.abscessus_ATCC_199 AS----GSRDPTALIAAARESIVS-------------------------- MAV_2362|M.avium_104 LM----AVNEPAVMLAAAHNTLSQ-------------------------- MMAR_4234|M.marinum_M I----AELGKPAALLRAARASLGRKV------------------------ MUL_0955|M.ulcerans_Agy99 I----AELGKPAALLRAARASLGRKV------------------------ Mb1236c|M.bovis_AF2122/97 LPASGADIGRPAALLRAARSSLTG-------------------------- Rv1204c|M.tuberculosis_H37Rv LPASGADIGRPAALLRAARSSLTG-------------------------- Mflv_4479|M.gilvum_PYR-GCK V----SGGEEPTTLLRAARESLR--------------------------- TH_4663|M.thermoresistible__bu T----GGGGEPATVLRTARESLCGPVLR---------------------- MLBr_01753|M.leprae_Br4923 LVGPGGVGKTRLALQVVARVADEFSGELSYFDLAPDTDHDIFPITVLDNL .: *: : MSMEG_4205|M.smegmatis_MC2_155 -----DGDVVVGVDDAHLLDQLSATLLHQFAVDHAGHVVATVRNGEPVPD Mvan_4065|M.vanbaalenii_PYR-1 -----QGECVVGVDDAHLLDELSATLLHQIAVDQSGRILATVRSGEPVPD MAB_3907c|M.abscessus_ATCC_199 -----TANPIIGIDDAHLLDDLSATLLHQIAVDHVGHVVATVRSGEPVPD MAV_2362|M.avium_104 -----DKNLVVVVDDAQLLDPLSATLVNQLAAWRSARLIVTIRSGEPVLD MMAR_4234|M.marinum_M ----RQGELLLIVDDAHDLDILSATLVYQLALAGAARMIVTARAEVAP-E MUL_0955|M.ulcerans_Agy99 ----RQGELLLIVDDAHDLDILSATLVYQLALAGAARMIVTARAEVAP-E Mb1236c|M.bovis_AF2122/97 ----DAGDLLLVVDDAHNLDPLSATLVYQLARAGAARLVVTVASEAEPPD Rv1204c|M.tuberculosis_H37Rv ----DAGDLLLVVDDAHNLDPLSATLVYQLARAGAARLVVTVASEAEPPD Mflv_4479|M.gilvum_PYR-GCK ----SAHGLLLVVDDAHHLDTLSATLVHQLAVTDNAHIMLTVREGEPVPD TH_4663|M.thermoresistible__bu --DRTRTGLLLIVDDAHHLDTLSATLVHQVAVSTPASLLLTVRDGEPVPD MLBr_01753|M.leprae_Br4923 RRCIGDRRMLMVLDNCEYLLDVCANVMTTLLG-ACPSLTILATSREPIGV :: :*:.. * :.*.:: . : MSMEG_4205|M.smegmatis_MC2_155 AVTSLWKDGYLQRFELQPFSKQQSIALIETVLGGTLEGLSADVMWESSGG Mvan_4065|M.vanbaalenii_PYR-1 AVTSLWKDGYLRRIELQPFSKEQSVRLVESVVGGRLEGLSADLMWESSGG MAB_3907c|M.abscessus_ATCC_199 AVTALWKDNYLQRFELDPLTQRQSIALVEKVLGGPLEGLSADVMWRSSRG MAV_2362|M.avium_104 AVTALLKERLLLTVHVDPFTREQTELLAGTVLGGPVDPWVVDELLQRSSG MMAR_4234|M.marinum_M AIAALWTDNLLDRIDVAPPD------------------------------ MUL_0955|M.ulcerans_Agy99 AIAALCTDNLLDRIDVAPPD------------------------------ Mb1236c|M.bovis_AF2122/97 AIAALWSDDLLTRVAIEPLDRAQTAAFVESALDATLDVADADELFRRSLG Rv1204c|M.tuberculosis_H37Rv AIAALWSDDLLTRVAIEPLDRAQTAAFVESALDATLDVADADELFRRSLG Mflv_4479|M.gilvum_PYR-GCK AVTALWKDSILSRHDIAPFDRRESGLLLEQILGGTVEDVSTVRMFEISQG TH_4663|M.thermoresistible__bu AITALWKDDLLARIDIEPFSQAECERLLADALGGRVESASAERLYAISEG MLBr_01753|M.leprae_Br4923 AGEVIWRVSMLSPADEAVELFTERAALVQPGFSVTDGNRQIVTEICQRLD * : * MSMEG_4205|M.smegmatis_MC2_155 NPLFLRNMVEGAVDAGTLTEVNGVWQFRGPTVIPSGLAELLDDRLAHAGE Mvan_4065|M.vanbaalenii_PYR-1 NPLFLRHLVEGSIDAGTLRKVGDVWQLRGPTAVPSGLASLLQDRLDHAGP MAB_3907c|M.abscessus_ATCC_199 NPLFLRHLVEGSMQAGSLTEVNGVWQLRGDAVVPSGLDTLIGDRLEHVDD MAV_2362|M.avium_104 NPLLLRGFLTAGRDTGALFRTAEGWQLRGPLRGDRELHDALEYRLQSLSS MMAR_4234|M.marinum_M ----------------------------GKTKQS--EPADVDEFIAELPA MUL_0955|M.ulcerans_Agy99 ----------------------------GQTKQS--EPADVDEFIAELPA Mb1236c|M.bovis_AF2122/97 NPLYLRHLID----GGGLEHVDGRWRCRDEDRRP--LSGVIDEYLCALPE Rv1204c|M.tuberculosis_H37Rv NPLYLRHLID----GGGLEHVDGRWRCRDEDRRP--LSGVIDEYLCALPE Mflv_4479|M.gilvum_PYR-GCK NPLYLRHLVDAALGTGSLRQVEGVWQLRGEMTLSPQLTTLIDAHLTNLPE TH_4663|M.thermoresistible__bu NPLYLRHLVTGTVASGALREVEGIWQLRGEVALTPQLSTLIDQHLSALPD MLBr_01753|M.leprae_Br4923 GMPLAIELAAARIRTLSLTEIADG--LDDRFRLLTGGARTAVRRQQTLRA . MSMEG_4205|M.smegmatis_MC2_155 DVMNALKLLSLCEPLDIDAFAELAG---EEAVDSAEMRGLIRIVTDAGGT Mvan_4065|M.vanbaalenii_PYR-1 DVLNALRLLALCEPLDIHALTELAG---DDAVDAAEACDLIRFQQD-GTV MAB_3907c|M.abscessus_ATCC_199 TVFSALKVLSMCEPLDIDTLCEIAS---DEAVDAAEIADLIRVERD-GVR MAV_2362|M.avium_104 EEREVVEILATAGLLNWDILRDICD---AEAVAALERRGLIRLVTD-GSH MMAR_4234|M.marinum_M PARAVLDYLTVEEPLSLADLTVLAGEGAVQQAVELGAAETRVRGEP-DEP MUL_0955|M.ulcerans_Agy99 PARAVLDYLTVEEPLSLADLTVLAGEGAVQQAVELGAAETRVRGEP-DEP Mb1236c|M.bovis_AF2122/97 PARAVVDYLAIAEPLARTDLVALVGGEQLDTLGQAEAAGAVRVGPD-SDT Rv1204c|M.tuberculosis_H37Rv PARAVVDYLAIAEPLARTDLVALVGGEQLDTLGQAEAAGAVRVGPD-SDT Mflv_4479|M.gilvum_PYR-GCK PVRSVLEFLAIDDPLSVDDLAALTG---IDAVDAAETCGVVTITDR-AGA TH_4663|M.thermoresistible__bu QIRTVLAYLAIEEPLTVADLSDLVS---PEAVEAAEAAGAVTVDER-GAD MLBr_01753|M.leprae_Br4923 SMDWSYALLTESERALFRRLSAISGTFDLKVAYAVGHDDLEEPDQVFDRL *: : : . . MSMEG_4205|M.smegmatis_MC2_155 LTARFAHPLFAEVVRRRVGTASARKLRGRIAKILRDRD--------LSTA Mvan_4065|M.vanbaalenii_PYR-1 LNARFSHPLVGDVVRDRIGHATERRLKGQLVELLRRRE--------LSTA MAB_3907c|M.abscessus_ATCC_199 TVVRFSHPMFGEAVRRRVGTASGRRLRGKLVRVLRDRD--------LGTA MAV_2362|M.avium_104 AVAQLTHPMLGEAATRHAGMVRTRQLNGKLARALQKHERTGSRHLRLPHL MMAR_4234|M.marinum_M AVVYTAHPLFAKRARVALGDDGARQRRTELVTLLSQHP--------NEHL MUL_0955|M.ulcerans_Agy99 AVVYTAHPLFAKRARVALGDDGARQRRTELVTLLSQHP--------NEHL Mb1236c|M.bovis_AF2122/97 SEIFVGHPLYADRARAVLTAEHAHALRVSLVAQLAKHP--------SDHV Rv1204c|M.tuberculosis_H37Rv SEIFVGHPLYADRARAVLTAEHAHALRVSLVAQLAKHP--------SDHV Mflv_4479|M.gilvum_PYR-GCK LYAHPFHPIYTERVRSSLGLLAMRRLRKLLAGRMSVRA--------PGNL TH_4663|M.thermoresistible__bu LIVHPAHPLYTETVRAGLGRLTRRSLRTALVARWSRRP--------PDNV MLBr_01753|M.leprae_Br4923 TMLIDKSLVIVEGRQGGSRYRLLETVRQYAMKKLEESNE-------VDLV : . . . MSMEG_4205|M.smegmatis_MC2_155 ASRIRLAQLCIESDRGAD---VDLLITAAKDAVFLSNLPLGEQLARAAFD Mvan_4065|M.vanbaalenii_PYR-1 ASRIRMAQLSIDSDQLLD---IDLLISATKDAIYLFNMPLGQRLAKVAFD MAB_3907c|M.abscessus_ATCC_199 SNRIRLARLSIDCDEPVD---VDLLVTAAKDAVYLSNLPLGEELARAAVD MAV_2362|M.avium_104 QSRIRLAEFMLHSDMEPD---LDVITEAARDALAMSNVQLGEELARFALD MMAR_4234|M.marinum_M SDRLRLASLALDTDALQP---VDDVVESAEQALRLGDLTLAERLAQAALD MUL_0955|M.ulcerans_Agy99 SDRLRLASLALDTDALQP---VDDVVESAEQALRLGDLTLAERLAQAALD Mb1236c|M.bovis_AF2122/97 SDQLRLSSLAIDVPASATPAAVTDAATAAGQALRLGDVRLAERLARAALD Rv1204c|M.tuberculosis_H37Rv SDQLRLSSLAIDVPASATPAAVTDAATAAGQALRLGDVRLAERLARAALD Mflv_4479|M.gilvum_PYR-GCK STRLRMAALAMGTDEPPS---ADELVGLSWEAMRLGDLALGERLARAALD TH_4663|M.thermoresistible__bu SDRLRLAALAVNSQTPPP---ATDLIATSWEAMQLGDLLLGEQLARGALG MLBr_01753|M.leprae_Br4923 LARHRDHYMALGALLDTPG-DIDHEQLVEQVETELDNLRSAFAWSRETGD : * : : : :: . :: : . MSMEG_4205|M.smegmatis_MC2_155 HGGGLPAATLLS----------RALLWQGHPAQADNILARFPPDHMDEME Mvan_4065|M.vanbaalenii_PYR-1 RTGSLEAAELLS----------RTLLWQGRPAAAEAILARFSPDDLDELQ MAB_3907c|M.abscessus_ATCC_199 GGGGLQAAAMLS----------RSLLWQGRPEQAEEILAAFDPDDLDELS MAV_2362|M.avium_104 RGGGLPAALVLA----------EAVSWQGRGEEAGFVLAHAEPDGDDDWL MMAR_4234|M.marinum_M RSGGLQARLVLG----------QALAWRGRGREAGQVLTAVDPGQLSEAE MUL_0955|M.ulcerans_Agy99 RSGGLQARLVLG----------QALAWRGRGREAGQVLTAVDPGQLSEAE Mb1236c|M.bovis_AF2122/97 RSDALAARLPLA----------YALGWQGRGREADAVLAAVNPAELTETE Rv1204c|M.tuberculosis_H37Rv RSDALAARLPLA----------YALGWQGRGREADAVLAAVNPAELTETE Mflv_4479|M.gilvum_PYR-GCK QADGLAARLPLA----------HSLSWQGRGRDADDVLNPVDPDTLTQWD TH_4663|M.thermoresistible__bu QSDTLAARLPLA----------HALAWQGRGREADDVLAAVDPDRLTEFD MLBr_01753|M.leprae_Br4923 IAGALQLASSLQPIWFGRGHMYEGLAWFDSIFEHKNIEHLVAPKEVLARA . * * : * . : * MSMEG_4205|M.smegmatis_MC2_155 LVQWGIPRLSILFWSMGDVPLAHQVLGELNSRVTHPILQLIIDATEAG-- Mvan_4065|M.vanbaalenii_PYR-1 LVRWGTPRASHLFWAMGDVERAHEVISLVRERTTHPSLRLFVEAAAAA-- MAB_3907c|M.abscessus_ATCC_199 LVLWGIPRISIAFWSMGENERAHELLALLHERVRHHILKPVVDATDAA-- MAV_2362|M.avium_104 IARWGCLRAANLFWGCGDAEAARREADTVKKRVSSEAGLHLIDALELS-- MMAR_4234|M.marinum_M LMAWAVPQAANQFWMLGEPERATAFLQTTRNRVTDLTARTTLDALTAT-- MUL_0955|M.ulcerans_Agy99 LMAWAVPQAANQFWMLGEPERATAFLQTTRNRVTDLTARTTLDALTAT-- Mb1236c|M.bovis_AF2122/97 LMAWAIPRAANRFWMLNEPERATAFLQTTRSRVTEPTARSTLDALAAT-- Rv1204c|M.tuberculosis_H37Rv LMAWAIPRAANRFWMLNEPERATAFLQTTRSRVTEPTARSTLDALAAT-- Mflv_4479|M.gilvum_PYR-GCK LMAWTLPKAANRFWMLSESEEAVEYLRQMRARITERGALHTIDALAAT-- TH_4663|M.thermoresistible__bu IMAWTLPKAANQFWMLSESAEAIALLDRMRTRLHQPAAVTAFDALAAT-- MLBr_01753|M.leprae_Br4923 VANKVMLHAILASSPPDGSDLVTQAQQALTMAREIGDSAVLARALTACGF : : . . * MSMEG_4205|M.smegmatis_MC2_155 MAVHENRITEGLAIAERVLDHPECPRQATDFAAFACGLAMPVAGRGEAFL Mvan_4065|M.vanbaalenii_PYR-1 MAVHENRIDEGIAAALQVLDNPLAPGQAVEFAAFAAGLAMPVAGRGDEFE MAB_3907c|M.abscessus_ATCC_199 IALHENRFDEGLARAHAVLSDPVAPKQAVEFAAFGVGLTLPVAGRGHEFE MAV_2362|M.avium_104 MAFFRGDVETTTELGPGLCESDAVP-MATTWAAVPTCAALAATGRYSEVG MMAR_4234|M.marinum_M FAMNSGNVPRAITLATEVLAEPSADDTAIAWAASAAALASARMGRFADVP MUL_0955|M.ulcerans_Agy99 FAMNSGNVPRAITLATEVLAEPSADDTAIAWAASAAALASARMGRFADVP Mb1236c|M.bovis_AF2122/97 FAMNSGNLPRAITLATEVLSGPAADDMAVAWAASAAALSSARMGRFGDVD Rv1204c|M.tuberculosis_H37Rv FAMNSGNLPRAITLATEVLSGPAADDMAVAWAASAAALSSARMGRFGDVD Mflv_4479|M.gilvum_PYR-GCK FAMNAGDPAEAVTVAKGILAADDAQDLAVAWASAAATLSSARMGRFAEVD TH_4663|M.thermoresistible__bu FAMNAGQPRTALELAGRVLQTPESQDLAVAWAAATATLSSARMARFDEVE MLBr_01753|M.leprae_Br4923 SSGYDTEVARPYFAEAVELARTQGDKWTLSQIRLWGVVGFCVSGDPVALR : : . . MSMEG_4205|M.smegmatis_MC2_155 PIASRCRAQRK-TTDGMIRIMVFYGEVLALAYTGQFDLARQRAEEYAEFS Mvan_4065|M.vanbaalenii_PYR-1 PIAARCRADQK-PTDGMIRVMVRYCDVLALTHLGELDLAGRRAAEYADFS MAB_3907c|M.abscessus_ATCC_199 PIAQRCRDDKKRTTDGLIAAMVRYCDVLALTYTGQLDLAEERVAEYTKFS MAV_2362|M.avium_104 RIADIGVRAAMSCGMGLHRFNIGISEIIAATDAGD-DRAAERIYKRYAAM MMAR_4234|M.marinum_M QLAQRASEAEH---PGLLRFTVGLAQITTLLMAGEVAQAQELAQRFTDFA MUL_0955|M.ulcerans_Agy99 QLAQRASEAEH---PGLLRFTVGLAQITTLLMAGEVAQAQELAQRFTDFA Mb1236c|M.bovis_AF2122/97 RLAERASAAEH---PGLLRFTVGLAQITSLLLAGDVAPAQELAKRFTDFA Rv1204c|M.tuberculosis_H37Rv RLAERASAAEH---PGLLRFTVGLAQITSLLLAGDVAPAQELAKRFTDFA Mflv_4479|M.gilvum_PYR-GCK GLAQRGLDAAH---PGLLRFTLGLGQTLALIMNADVASAEHLARHYLSFS TH_4663|M.thermoresistible__bu THAARGLAAQH---PGLLRFTIGLGQITRLILAGXLTRADFLAHHYLSFC MLBr_01753|M.leprae_Br4923 AAAEAADDLAQEIGDRFVSLQCRLLLSIAQLWQGDMDGAIVRSGEVVAGA * : . * . MSMEG_4205|M.smegmatis_MC2_155 SAGQFAGWAIAKIMAGAAAMHSGRFRDAISAIEQALAALNAEISLPWQL- Mvan_4065|M.vanbaalenii_PYR-1 SVGQFLAWAIAKIMAGVVATARGEFPDAVTCIEQALAALNAETSLPWQL- MAB_3907c|M.abscessus_ATCC_199 SAGQFLAWAIARIMAGVVATQRGLFREAIEAFEQALAAQRADRPLPWQL- MAV_2362|M.avium_104 AEGLPGAEAMVDAMLGVVRLARGEFPAACAAFTRSISLFAKGFPSPWLV- MMAR_4234|M.marinum_M EL-QQPGRAIGEVLLAHVLIVKGEFGAAAAMLEPAAAELERTG-YSWGP- MUL_0955|M.ulcerans_Agy99 EL-QQPGRAIGEVLLAHVLIVKGEFGTAAAMVEPAAAELERTG-YSWGP- Mb1236c|M.bovis_AF2122/97 -------------------------------------------------- Rv1204c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_4479|M.gilvum_PYR-GCK EF-QQPGRAIGEVLLGHTLLASGRFGDAVTLLRQAAAALTYTG-YSWGP- TH_4663|M.thermoresistible__bu EF-QQPGRAIGEVLLAHILIARGDLPTATTLLRQAAAALSSTG-YSWGP- MLBr_01753|M.leprae_Br4923 EAAHDTVTRTFGLYVQTRALVHRDVSAALVTAGLVVEAAAELSGVYQGIG MSMEG_4205|M.smegmatis_MC2_155 -PGRLLLARAYAAVGEVIEAERVLDDAMEHSG----------AFMALHEP Mvan_4065|M.vanbaalenii_PYR-1 -PGRLLLARAYAALGRTDEAERVLNDAAEHSG----------PSAAIHEP MAB_3907c|M.abscessus_ATCC_199 -PARLLLARAYAALGRAVDGERVLDEAREHSG----------PHVAIHMP MAV_2362|M.avium_104 -VVGAFQAQAEGARGDSTAAAAALWRADRAYG----------PHAAVFLP MMAR_4234|M.marinum_M -LSLMLLATAIAQQGNIAETAKALRRAETRHG----------TKSALFAP MUL_0955|M.ulcerans_Agy99 -LSLMLLATAIAQQGNIAETAKALRRAETRHG----------TKSALFAP Mb1236c|M.bovis_AF2122/97 -------------------------------------------------- Rv1204c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_4479|M.gilvum_PYR-GCK -LALTGLAQALGQQGRAADASAVLTRAEASHG----------MRSALYAP TH_4663|M.thermoresistible__bu -LALMQLTQVLGARGDADGASEALRRAEHSHG----------TRSELYAP MLBr_01753|M.leprae_Br4923 YAAMVFAALAMGDVAAAVEASEACRPHLGADHGLVAIHLELMAAVALARG MSMEG_4205|M.smegmatis_MC2_155 QRTLAKACVAAAKGAHRSAIDIARSAADLARSSEQHAVEAEALHHCARFG Mvan_4065|M.vanbaalenii_PYR-1 QRLISRSWYAAAKGMERRALELARAAAEIARQSGQYALEAEALHHATRFG MAB_3907c|M.abscessus_ATCC_199 QMMLAKAWLVAARGSDRGAVDAARRAADAAHSAGQYALEAEALHHAARFG MAV_2362|M.avium_104 ELELARAWERAAAGDTQAATTHATQAAEIARAAGMHAAEMRTRHAAVRFG MMAR_4234|M.marinum_M ELSLARAWAKATVRDQAGALFDTREAARAAERGKQSAVALCVWHDAVRLG MUL_0955|M.ulcerans_Agy99 ELSLARAWAKATVRDQAGALFDTREAARAAERGKQSAVALCVWHDAVRLG Mb1236c|M.bovis_AF2122/97 -------------------------------------------------- Rv1204c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_4479|M.gilvum_PYR-GCK DLALARAWTLAAARDLRGAVASARDAVHAAVQSGQDAVALRALQDCARLG TH_4663|M.thermoresistible__bu ELALX-XXXWRGLRDESGHLAAYRITVDDRLP-----ETLADLWD----G MLBr_01753|M.leprae_Br4923 DVIVARRLADNSVSATTGWHQMAALTTRARIAMAQGEPELARADIHAALA MSMEG_4205|M.smegmatis_MC2_155 DRTVARRLQGLVDRVDGPLARLYAQHAAAVAAADPVALDAVSSAFEQAGL Mvan_4065|M.vanbaalenii_PYR-1 DRSTAPRLAELTGVVHGSVVGLLARHAAAFAAGDAAALDVVSADFESAGL MAB_3907c|M.abscessus_ATCC_199 DRTVGRRIESLCTRVHGPLTGLYARHALAVAHSDITGLEAVSADFEAAGL MAV_2362|M.avium_104 DRSQTARLERLARILDTPLAEAAADHARGLTQRDGDLLDAAAQQFADLGA MMAR_4234|M.marinum_M DTRALAPVTRLAAEIDCKVGNIVVRHARALADNDAGALASVADELAAIGM MUL_0955|M.ulcerans_Agy99 DTRALAPVTRLAAEIDCKVGNIVVRHARALANNDAGALASVADELAAIGM Mb1236c|M.bovis_AF2122/97 -------------------------------------------------- Rv1204c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_4479|M.gilvum_PYR-GCK DTHGLATAVRLSDRIGCVTGPLCVAHLRALAAGDGAALDAVSADLETAGL TH_4663|M.thermoresistible__bu SAAEVWTAIEFS---GTTAHPMITAG----------------CALRSEKK MLBr_01753|M.leprae_Br4923 CGADIQASLGISDSMELLAELISQGDNHRQAGRLFGAASAQREKTGEVRF MSMEG_4205|M.smegmatis_MC2_155 MLSAADAAAQAVLLHDKAGHRRQSTESAAHALQLAGRCGGAATPAIRAAA Mvan_4065|M.vanbaalenii_PYR-1 MLSAADAAAQAALLHDSAGDRRRTNESGANALRLAEKCGGATTPAIKAAA MAB_3907c|M.abscessus_ATCC_199 LLSAADAAAQAVALRMRAGDRGKGSDAAARVLRMADRCGGVVTPAILAAA MAV_2362|M.avium_104 LACAADAAAQAAGEHARRGDRGKKFESSAWAHALASRY-ELHTPAVEAAA MMAR_4234|M.marinum_M HAAAADAAAQAERAGGR--------------------------------- MUL_0955|M.ulcerans_Agy99 HAAAADAAAQAERAGGR--------------------------------- Mb1236c|M.bovis_AF2122/97 -------------------------------------------------- Rv1204c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_4479|M.gilvum_PYR-GCK PAAAADAAAQATFAHQRRGDRAGEVASRSRASRLSQVCGAPATPALEQVL TH_4663|M.thermoresistible__bu PEAAGPLPALTPQRGLHR--PALEALAPTSGRRLPG-------------- MLBr_01753|M.leprae_Br4923 KVWDAGYESAVAVLRGAMGCKDFDSAWAEGAAMPIDDAITYAQRGRGNRK MSMEG_4205|M.smegmatis_MC2_155 RPLP----VTAREREVAALVAQGLLNREIAERLTVSVRTVEGHIYRACIK Mvan_4065|M.vanbaalenii_PYR-1 RPLP----LTPREREIAELVAAGLSNRHIAEQLVLSVRTVEGHVYRACFK MAB_3907c|M.abscessus_ATCC_199 KPLP----ISSREREIAVLIGEGLSDKDIATRLQLSVRTVEGHIYRARMK MAV_2362|M.avium_104 RPLP----FSGRERQIVNLVAAGLSNREIADRLVISVRTVEGHLYRLFTK MMAR_4234|M.marinum_M -------------------------------------------------- MUL_0955|M.ulcerans_Agy99 -------------------------------------------------- Mb1236c|M.bovis_AF2122/97 -------------------------------------------------- Rv1204c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_4479|M.gilvum_PYR-GCK NPMP----LTGREREVAVMVSQGLTNKAIAQRLSVSVRTVEGHVYRACMK TH_4663|M.thermoresistible__bu EPVP----LPDGLLDSLFWPVRGVRSTARQRRTARQVETES--------- MLBr_01753|M.leprae_Br4923 RPTTGWESLTPAEHNVIRLVSEGLDTKDIAARLFVSVRTVHTHLTRIYSK MSMEG_4205|M.smegmatis_MC2_155 LGVADRDELARMIWTD----------LTPLEADPR------- Mvan_4065|M.vanbaalenii_PYR-1 LDVADRDELAKLIRKK----------S--------------- MAB_3907c|M.abscessus_ATCC_199 LDADDREEFAKIVGSD----------LKPPEAS--------- MAV_2362|M.avium_104 LGINSREQLTLLVAREPRGRRELLGHSNPSLGDQDDVHPHAG MMAR_4234|M.marinum_M ------------------------------------------ MUL_0955|M.ulcerans_Agy99 ------------------------------------------ Mb1236c|M.bovis_AF2122/97 ------------------------------------------ Rv1204c|M.tuberculosis_H37Rv ------------------------------------------ Mflv_4479|M.gilvum_PYR-GCK FGVPDRAALASTVGGMHGREGTA------------------- TH_4663|M.thermoresistible__bu ---VDTAPVSRT------------------------------ MLBr_01753|M.leprae_Br4923 LGLTSRVQLVQEAARHN-------------------------