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ANPAPEHAVDLPRAVQEMLAGVPSRPAKLLVSGGIGTGKSTVLAAVRATLREAGRTVLTRPPRPDDDQGA VFVIDDAHHLADDEIDCLTERSTDPSSTVVVAAEPLAHRPVLRALATALERENPIVALGPMSTAEVGRLL TATLGSPPPPDTVRAVLAVTAGLPFLVRAVATSAAEPEEAARYALIERVRHLGEQTRDTLLLTSLSLDLG PDDVAGALRVSGTDASVLVDRARAGGLVEPAYDKRFLRLVHTSVAQIAGTSRHHDIEIALLHSQLEKATL SPELAVRLAEHGVRDDRLAAALTDHAVQVRGQPARAARLYRAAARAGSAALNARLADALALSGDCATAGR MADDLLSSDDPAERAAAVRIAASIAMHDGSAAQAADLFRWLGPYPDAAVGSAGTVALLAAGDAEAARAAL NTELSGPPTSAARAARSLAEGLVASLDQPFTTTVARLGQAVTADPHTDSVGPDTPAALVALAALHGGDSV RARSVIGRAVRTGAPGAENGTPPPAPFWAARHRLLLGWVKMLDGQLTAAGADVSAVESGPPLHRRDALWA AALRTAIARRSGDSGAIQRHWFAAMEVLAEYSIDLYSLLPLGELWVAAARMRRIDRLEHPLAEAFGLLDA LGKPVLWSMPLHWAGVHAGILANSPGAVAPHGQALTAAAGHSPFARALAGAGRTWLRVLANHVDVDEVAA AARGLAQFGLTWDATRLASQAALQTSDARVSQAMLQLARDLKQSGAADDVSAPETPRAPVATQAGAPAGS ARLSDREREVAELLLLGMPYRDIGNQLFISAKTVEHHVARIRRRLGAESRSEMLSMLRAMFSPQG*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_0691 | - | - | 100% (836) | putative transcriptional regulatory protein |
M. smegmatis MC2 155 | MSMEG_1901 | - | 8e-14 | 25.33% (754) | DNA-binding HTH domain-containing protein |
M. smegmatis MC2 155 | MSMEG_3290 | - | 2e-10 | 23.96% (768) | regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0346c | - | 0.0 | 59.40% (830) | transcriptional regulatory protein |
M. gilvum PYR-GCK | Mflv_0277 | - | 0.0 | 61.16% (829) | response regulator receiver protein |
M. tuberculosis H37Rv | Rv0339c | - | 0.0 | 59.40% (830) | transcriptional regulatory protein |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_4292 | - | 0.0 | 46.59% (822) | LuxR family transcriptional regulator |
M. marinum M | MMAR_0612 | - | 0.0 | 58.51% (834) | transcriptional regulatory protein |
M. avium 104 | MAV_0578 | - | 4e-17 | 24.03% (874) | transcriptional regulator, LuxR family protein |
M. thermoresistible (build 8) | TH_4413 | - | 5e-11 | 24.51% (559) | PUTATIVE putative response regulator receiver protein |
M. ulcerans Agy99 | MUL_2876 | - | 4e-08 | 30.61% (147) | putative regulatory protein |
M. vanbaalenii PYR-1 | Mvan_0620 | - | 0.0 | 63.46% (843) | response regulator receiver protein |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_0277|M.gilvum_PYR-GCK ----------------------------------------MLPAAREAIA Mvan_0620|M.vanbaalenii_PYR-1 -----------------------------MTTPAAPRLSDLPPAAREAVA MSMEG_0691|M.smegmatis_MC2_155 -----------------------------MANPAPEHAVDLPRAVQEMLA Mb0346c|M.bovis_AF2122/97 -----------------MQHRGCKNRGQAYDASVTDSLTEVPPAARRALL Rv0339c|M.tuberculosis_H37Rv -----------------MQHRGCKNRGQAYDASVTDSLTEVPPAARRALL MMAR_0612|M.marinum_M ------------------MSEGHASRD---DTSAPPDSAAVPAPARGLID MAB_4292|M.abscessus_ATCC_1997 ---------------------------------MSGTFDGIASAITAITG MAV_0578|M.avium_104 MIGGELLIGRDSELAAIRRALNGADHHRGVVIAGAAGVGKTWLARAALRR TH_4413|M.thermoresistible__bu -------------------------------------------------- MUL_2876|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0277|M.gilvum_PYR-GCK AVDADPRAATKSLVTGGIGTGKTTLLAAMRTTFRSAGRQVLSRPPDAGTP Mvan_0620|M.vanbaalenii_PYR-1 AMEADPHAPVKLVVVGGAGSGKSTVLTAVRAVLRASDRPVRSRPRGGETA MSMEG_0691|M.smegmatis_MC2_155 GVPSRP---AKLLVSGGIGTGKSTVLAAVRATLREAGRTVLTRPP---RP Mb0346c|M.bovis_AF2122/97 ELANAPTVPVKVLITGGIGTGKTTVLAAARDTLRRSGLTVLACPPPDGEP Rv0339c|M.tuberculosis_H37Rv ELANAPTVPVKVLITGGIGTGKTTVLAAARDTLRRSGLTVLACPPPDGEP MMAR_0612|M.marinum_M ELASGGATSVKALIGGGIGTGKTTVLGTVRDALRRAGVTVRAHPTKDCDP MAB_4292|M.abscessus_ATCC_1997 PLSAGH--AVKVLVNGTAGSGKTFVLSRIREALGSAGTPAVNHVPEAAPG MAV_0578|M.avium_104 AGASGEQIKWIVGTQSAQALPLGAFIGLLGDAMSEPLTSVRRVIETFVAR TH_4413|M.thermoresistible__bu -------------------------------------------------- MUL_2876|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0277|M.gilvum_PYR-GCK GDGAGYALVVDDAHLLGDDDLDRLTDLAGDPASTVVIATQALMHRS---- Mvan_0620|M.vanbaalenii_PYR-1 ED---TVTVVDDAHLLDRAELDQLTELVTDPTAGVVIATEPLAHHG---- MSMEG_0691|M.smegmatis_MC2_155 DDDQGAVFVIDDAHHLADDEIDCLTERSTDPSSTVVVAAEPLAHRP---- Mb0346c|M.bovis_AF2122/97 PE---TALVIDDAQLLTDTELLRLTERVADSRLTVVAAAEAREHHR---- Rv0339c|M.tuberculosis_H37Rv PE---TALVIDDAQLLTDTELLRLTERVADSRLTVVAAAEAREHHR---- MMAR_0612|M.marinum_M SE---VALVVDDAHLLAEDELLRLAEWVADPRATVVVGAQLHQQHH---- MAB_4292|M.abscessus_ATCC_1997 PN--TGPFVIDDADSLTDRQLETLRAVVENDPAAIIVVAAAPRRNP---- MAV_0578|M.avium_104 QRRGRVVVGVDDAHLLDGLSALVVHQLAQSGGVRLVVTVRTGSHQPDAVT TH_4413|M.thermoresistible__bu -------------------------------------------------- MUL_2876|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0277|M.gilvum_PYR-GCK -----------RLQVLMTVLARENPEVALRPLTAAQVQEAATSALGASVG Mvan_0620|M.vanbaalenii_PYR-1 -----------PLRELVTALEREHAAVALGPLPPVEVSRIAAAALGLPAA MSMEG_0691|M.smegmatis_MC2_155 -----------VLRALATALERENPIVALGPMSTAEVGRLLTATLGSPPP Mb0346c|M.bovis_AF2122/97 -----------ALRALTMALERDRPRISLGPLPVAEH------------- Rv0339c|M.tuberculosis_H37Rv -----------ALRALTMALERDRPRISLGPLPVAEH------------- MMAR_0612|M.marinum_M -----------ALRALATAIERERPQISLGPLPVADQ------------- MAB_4292|M.abscessus_ATCC_1997 -----------ALRSLFQALERESPAITLGPVNATDIGRMS------PLA MAV_0578|M.avium_104 ALWKDDLLTRLDLEPLSAAATREVIESTLGGPVDARCAARFRRLTGGNTL TH_4413|M.thermoresistible__bu -----------------------VVRRSGG-------------------- MUL_2876|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0277|M.gilvum_PYR-GCK PELTRLLVSVTGGFPFLVSAALSAIPDG--AQSARQAAHFALIERLARLD Mvan_0620|M.vanbaalenii_PYR-1 PELVRALLSATAGLPFLLRPALAAAGDG--VASMRQAARFGLIERLRGFD MSMEG_0691|M.smegmatis_MC2_155 PDTVRAVLAVTAGLPFLVRAVATSAAE------PEEAARYALIERVRHLG Mb0346c|M.bovis_AF2122/97 ------LRDCTAGLPFLIHAVSARAQA------PAQAAKVALIERLRRLD Rv0339c|M.tuberculosis_H37Rv ------LRDCTAGLPFLIHAVSARAQA------PAQAAKVALIERLRRLD MMAR_0612|M.marinum_M ------LRDSTAGVPFLVEAVSRGTGS------PVPAARFALIERLRRLD MAB_4292|M.abscessus_ATCC_1997 APFAEQIAAASGGVLALTAAAVERLGDPDPLQSALRAIDTRVDELLRRLS MAV_0578|M.avium_104 FLRQLLSDQMAAGRMRRVAGVWMWDGDV----AVSASLSDTVGRQLGRLT TH_4413|M.thermoresistible__bu ----------------------------------APGLIALIEERIGLLA MUL_2876|M.ulcerans_Agy99 ---------------------------------------MGFSPRRAIPE . Mflv_0277|M.gilvum_PYR-GCK GHLLDTLLVMTLSPGLGP---DDVAAALRIPADEAVAAVDSARATALIDP Mvan_0620|M.vanbaalenii_PYR-1 ERLLDTLLVSSLSFDLGP---DDVAAALRLSSQEALTAVDRARASGLIEP MSMEG_0691|M.smegmatis_MC2_155 EQTRDTLLLTSLSLDLGP---DDVAGALRVSGTDASVLVDRARAGGLVEP Mb0346c|M.bovis_AF2122/97 EPTLDTLLMMSLTHELGV---SDVAAALGISVTDARGLVDRAHASGLIES Rv0339c|M.tuberculosis_H37Rv EPTLDTLLMMSLTHELGV---SDVAAALGISVTDARGLVDRAHASGLIES MMAR_0612|M.marinum_M EPTLDALLIMSLTQESGT---TDVAAALGVSTSDARQLVDRVHASGLVEP MAB_4292|M.abscessus_ATCC_1997 PMAQAAVLLMSLNPGIGA---SDVAAALALP--DAADLVDEALASGLIAG MAV_0578|M.avium_104 PPLALVVDTLSQCEPLPVDLLCDLASREDLVAAEAMGLVTVERTPRALMA TH_4413|M.thermoresistible__bu EPVGDVVDILAVGEPVDLGLLTRLTDPAAVEEADVRGLIAIEDGDRALVR MUL_2876|M.ulcerans_Agy99 RTVGGVIDVVDMP---------DPPAFPTLADDEHPGWASRPIRESDATR .: . : : Mflv_0277|M.gilvum_PYR-GCK AHTSQFLAAVHDGIAQIVGAARHHDVEMAVLDSQLALC--TLTADLALRI Mvan_0620|M.vanbaalenii_PYR-1 AHPLAFQRTLHDAVAQVVGAARHHDIEVSVLLSQLELS--TLTADLALRL MSMEG_0691|M.smegmatis_MC2_155 AYDKRFLRLVHTSVAQIAGTSRHHDIEIALLHSQLEKA--TLSPELAVRL Mb0346c|M.bovis_AF2122/97 SHTAAFLQSVHDAIAQIVGNAHHHEVETSLLRSQLDIS--PVSAELALRL Rv0339c|M.tuberculosis_H37Rv SHTAAFLQSVHDAIAQIVGNAHHHEVETSLLRSQLDIS--PVSAELALRL MMAR_0612|M.marinum_M SHPPAFVQLVHEAVVHIVGNTHHHEVETSLLRSQLDIS--PMSQDLALRL MAB_4292|M.abscessus_ATCC_1997 PGHVAFAARVHGCAARLLGAARHLDLERSLLRTQLEMG--SVSADLALAL MAV_0578|M.avium_104 RLAHPLFGELRRAGAGEMYLSTIRGRLATRLAQDQDAD-MQATVRRALLT TH_4413|M.thermoresistible__bu -LAHPLYGEVRRRRAAVTRLRRLRGLVADELAQAADADDLAQVVRRTTLL MUL_2876|M.ulcerans_Agy99 HYREAFGDCNVDP----------TDDPMAVVAEAIDVN---------AAA : : Mflv_0277|M.gilvum_PYR-GCK ADHGVRDDRLATALTDFAARVPDRPARAARLYRAATDAGTTA--VRPALA Mvan_0620|M.vanbaalenii_PYR-1 AEHGLRDERLATALTDLAGRTRGHPARAARLYRAAAEAGASA--PGVRLA MSMEG_0691|M.smegmatis_MC2_155 AEHGVRDDRLAAALTDHAVQVRGQPARAARLYRAAARAGSAA--LNARLA Mb0346c|M.bovis_AF2122/97 AEHGLRDERLADILTRYAADTRDASVRCARLYRAAVHAGAKG--LTVRLA Rv0339c|M.tuberculosis_H37Rv AEHGLRDERLADILTRYAADTRDASVRCARLYRAAVHAGAKG--LTVRLA MMAR_0612|M.marinum_M AEHGLHGERLATALAGYASAARGEPAQTARLYRAAVAAGATG--LKSQLA MAB_4292|M.abscessus_ATCC_1997 VGHGLRDLEVARLLSNWATTESD-PLSAADLYRAALTAGAEPDPIRVPLA MAV_0578|M.avium_104 LESDLDPQPELYLESARHAMTLLDLDLADRLANAAARAGAP--GAAGVRA TH_4413|M.thermoresistible__bu LDSDRRPDVDLFVRAARGAARIGDLPLAERLSGAAVRAGATV-EAAIVHA MUL_2876|M.ulcerans_Agy99 VRHALESQGDVHAVNALETLLDLSSLEREMIEDGAARRTLALLQVQEALS : .* : Mflv_0277|M.gilvum_PYR-GCK DALVLTGDCVTAGRLADDLLTS---QDPDERAAAVRIAASIALHDGAARQ Mvan_0620|M.vanbaalenii_PYR-1 DALALTGDCGTAGRLADDLLTA---PDPAERAAAVRIAASVALHDGGAEQ MSMEG_0691|M.smegmatis_MC2_155 DALALSGDCATAGRMADDLLSS---DDPAERAAAVRIAASIAMHDGSAAQ Mb0346c|M.bovis_AF2122/97 DALARTGDCTAAATLADDLLSS---PDATERAAAVRVAASVAVHDGNTGH Rv0339c|M.tuberculosis_H37Rv DALARTGDCTAAATLADDLLSS---PDATERAAAVRVAASVAVHDGNTGH MMAR_0612|M.marinum_M DALARTGDCAGAAELADELLGS---ADSAQRAAAVRIAASVAAHEGNAGQ MAB_4292|M.abscessus_ATCC_1997 ESLARAGDLAAAAAQADEVLAS---TDPAQRTAGVRVAAAIACHNGDSGQ MAV_0578|M.avium_104 MNLVLLGRGEQAEEALRAITDGADGDASDRHYWATVRAANLVWMLGRPAD TH_4413|M.thermoresistible__bu RALTWLGRGDQAETVLAAI------DVADHTRLAFMRASNMLWALSDPEG MUL_2876|M.ulcerans_Agy99 KLRAVDDVAMIVDRAPRELVES----------CGFDRAVLFRVHEGRLVM . . . : . * . . Mflv_0277|M.gilvum_PYR-GCK AADLFAWLGPAPDAVVGAAETIAALAVGDAAAVRSTAQGPPSGPPTAVAR Mvan_0620|M.vanbaalenii_PYR-1 AHSLFEWLGPVPDTVVAAAATIAAVAAGDAAAARSTAQMPAPGPPTSTAR MSMEG_0691|M.smegmatis_MC2_155 AADLFRWLGPYPDAAVGSAGTVALLAAGDAEAARAALNTELSGPPTSAAR Mb0346c|M.bovis_AF2122/97 AAELFGWLGPHPDTMVSSAATIVFAANGDLATARATLRLKDAGPPTMAAR Rv0339c|M.tuberculosis_H37Rv AAELFGWLGPHPDTMVSSAATIVFAANGDLATARATLRLKDAGPPTMAAR MMAR_0612|M.marinum_M AAELFGWLGPYPDAVVGSSAAIVLAAVGDLQTARAALDVKDTGPPTMAAR MAB_4292|M.abscessus_ATCC_1997 AAALYSWLGADMDGLTALSASPVFVGTGQLAKGRKSLEDNVGAPPTTSAT MAV_0578|M.avium_104 AALVLDGLAARPETPAQAAARCAVQACLDAVAARCQLAAERARAALDSES TH_4413|M.thermoresistible__bu AKRLIGQAAAG--MPADQRAHLDAFCAVHAAAMGQPDEVFRHAGAVVVDE MUL_2876|M.ulcerans_Agy99 ESAYFGEDREGAEKMVAFAQSVAPLLDHMLIETQMIR------------- . Mflv_0277|M.gilvum_PYR-GCK SARAITEGLVMTLDQPYPAAIARLSQAIAVDAVHG-VLPDTPAALVTLAA Mvan_0620|M.vanbaalenii_PYR-1 AASGLAAGLVMTLDQPYPAAVARLSQALGTDLGQAMALPDTPAALVTLAA MSMEG_0691|M.smegmatis_MC2_155 AARSLAEGLVASLDQPFTTTVARLGQAVTADPHTDSVGPDTPAALVALAA Mb0346c|M.bovis_AF2122/97 CARNLAEGLLLTMDQPYPVAMAKLGQAIATEQSLSQVIPDSPAALVTLAA Rv0339c|M.tuberculosis_H37Rv CARNLAEGLLLTMDQPYPVAMAKLGQAIATEQSLSQVIPDSPAALVTLAA MMAR_0612|M.marinum_M AARGLADGLLLTMGQPYPVAMAKLGQAIAAEQPITEATPDSPAALVTLAA MAB_4292|M.abscessus_ATCC_1997 AQRNAALGVIASVEGRGQEALSLLGQAVTQQPSTSSFIPDSTVALAALTM MAV_0578|M.avium_104 LPD--FHAMMASLALIMAMGALGQVDDLTAVAEQALRRATTSFEASHMRF TH_4413|M.thermoresistible__bu LPG--IIGAETAWALTLAAGEAGRTAEAVAAADTGYRLTARFSDAAYTRF MUL_2876|M.ulcerans_Agy99 ----------------------RHAPAIVRDARNDPRVNRPIVDFSLTHS Mflv_0277|M.gilvum_PYR-GCK LHGGDPVRARSVIGRAVLADSRPDRA----DATFVTSRHRLLQGWAYMQD Mvan_0620|M.vanbaalenii_PYR-1 LHGGDPVRARSVVGRAVHTDGQRESE----DATFVTRRHRLLQGWAYMQD MSMEG_0691|M.smegmatis_MC2_155 LHGGDSVRARSVIGRAVRTGAPGAENGTPPPAPFWAARHRLLLGWVKMLD Mb0346c|M.bovis_AF2122/97 IHAGDPVRARSVIGRAVRAG----------ADPLFQRRHLLLSGWIKMQE Rv0339c|M.tuberculosis_H37Rv IHAGDPVRARSVIGRAVRAG----------ADPLFQRRHLLLSGWIKMQE MMAR_0612|M.marinum_M IHGGDPVRARSVIGRAVRSG----------TDQVFHQRHLLLSGWIKMQE MAB_4292|M.abscessus_ATCC_1997 LHSGDTARARSILTGAIRADR---------RHDVFGVRHRLLAAWIAMLS MAV_0578|M.avium_104 WFGAVYGRACRLTGRIDEFVS---------TARRLADSARDVPGLAYANL TH_4413|M.thermoresistible__bu TLTDAHVTALILAGRIAAAVD---------TATVLDRQVGDLPGGTALLA MUL_2876|M.ulcerans_Agy99 YVAAPVMPTGKMIG------------------------------------ : : Mflv_0277|M.gilvum_PYR-GCK GQLAAAAAAIPAD-GDPRLHRRDALWAAALHTGIARRSGDTGAMQMHWRS Mvan_0620|M.vanbaalenii_PYR-1 GQLHAASAAVRAA-GDPGPHRRDALWAAALQTAVARRSGDSGAMQKHWYS MSMEG_0691|M.smegmatis_MC2_155 GQLTAAGADVSAVESGPPLHRRDALWAAALRTAIARRSGDSGAIQRHWFA Mb0346c|M.bovis_AF2122/97 GQLPSASADVAAASAGTHLHRRDALWAAALQTAISRRTGDIGALQQHWYA Rv0339c|M.tuberculosis_H37Rv GQLPSASADVAAASAGTHLHRRDALWAAALQTAISRRTGDIGALQQHWYA MMAR_0612|M.marinum_M GQLPSASADVAAACSGAPMHRRDALWAAALETAIARRSGDAGALQKHWNA MAB_4292|M.abscessus_ATCC_1997 GDLSGAVQWLPGA--QVELSRRDRLFAESLRTGIARRHGDTGPLRQHWQA MAV_0578|M.avium_104 ALLLGNAELARGAAAEAARLVQEALAGAQIHEVTSGLRPASY---FALAE TH_4413|M.thermoresistible__bu RGVAGRAALAAGRLDDAVAWLRDVVSVLFSADTAGGFYGFGYRYQHPYAT MUL_2876|M.ulcerans_Agy99 ------------------FLHADRLYSGRIVDEIDR-------------- : : Mflv_0277|M.gilvum_PYR-GCK AMDVLAESSADLFTVLPLGELWIAASRLRQVDQVRHSLDEVFGLLAALGD Mvan_0620|M.vanbaalenii_PYR-1 AMEVLAEYSIDVFTVLPLGELWVAAARMRQVERLRHTLDEVFAMLVGLGD MSMEG_0691|M.smegmatis_MC2_155 AMEVLAEYSIDLYSLLPLGELWVAAARMRRIDRLEHPLAEAFGLLDALGK Mb0346c|M.bovis_AF2122/97 AMEALAEYSLDLFALLPLGELWVAAARMRQVDQLQHTLDQALTLLDSLGN Rv0339c|M.tuberculosis_H37Rv AMEALAEYSLDLFALLPLGELWVAAARMRQVDQLQHTLDQALTLLDSLGN MMAR_0612|M.marinum_M AMEVLGEYSLDLFALLPLGELWVAAARNRQVDQLQHTLDQAFSLLNSLGN MAB_4292|M.abscessus_ATCC_1997 SMDALSAYSIDLYTLLPVGELWVAAARLRTLDVMTHHLDRAFAVLAHLGD MAV_0578|M.avium_104 AHGRLGHPAQANEAIAGARSCVPPDFLF-----MHTGLALATGWALAAGG TH_4413|M.thermoresistible__bu ALAVLGHTAAAATALATLDEREFPSWRY-----LDHERTIALAWLRAAQG MUL_2876|M.ulcerans_Agy99 --------------------------------------DTVWAFAEGFGY . Mflv_0277|M.gilvum_PYR-GCK PLLWSIPLHWAGVHAGILANSPDAVAPHGAALTAAAPHAQFAKALAAAGR Mvan_0620|M.vanbaalenii_PYR-1 PVLWAVPLHWAGVHAGILANSPDSVAPHGQALTAAAPHSSFARALAAAGR MSMEG_0691|M.smegmatis_MC2_155 PVLWSMPLHWAGVHAGILANSPGAVAPHGQALTAAAGHSPFARALAGAGR Mb0346c|M.bovis_AF2122/97 PALWSNSLHWAGVHAGILANSPESVAPHGQALGAMVAHSTLAQALSDAGR Rv0339c|M.tuberculosis_H37Rv PALWSNSLHWAGVHAGILANSPESVAPHGQALGAMVAHSTLAQALSDAGR MMAR_0612|M.marinum_M PVLWSNSLHWAGVHAGILANSPGAVAPHGQALGAAAAGNALAHALSVAGR MAB_4292|M.abscessus_ATCC_1997 PIAWSAPLRWAGVHAAILTNSPETLAPHGQALAAGAGSSTYARILATAGR MAV_0578|M.avium_104 QLREAVATAQAAARLARDRGQPTHELACIQAAAQWGDAAGAVRARALADA TH_4413|M.thermoresistible__bu AVSTSIQRLRAEAESARTAGRFAVELLCLQTAVQFGDRTCGPRLHQLEDR MUL_2876|M.ulcerans_Agy99 AYERTVLLERMRRQHAEVRS-----------------------ALASADE : . . . . Mflv_0277|M.gilvum_PYR-GCK TWLRVLADRVDVAEVTAAARGLALHGHTWDATRLAGQAALQTTDSRAAQA Mvan_0620|M.vanbaalenii_PYR-1 TWLKVLANQVDADEVSSAARGLAQYGHTWDATRLAGQAALQTTDPRVSQA MSMEG_0691|M.smegmatis_MC2_155 TWLRVLANHVDVDEVAAAARGLAQFGLTWDATRLASQAALQTSDARVSQA Mb0346c|M.bovis_AF2122/97 TWLRVLAENVDADEVTAAARSLSHVGLTSDATRLAGQAALQTSDARVSGA Rv0339c|M.tuberculosis_H37Rv TWLRVLAENVDADEVTAAARSLSHVGLTSDATRLAGQAALQTSDARVSGA MMAR_0612|M.marinum_M TWLRVLADQVDVDEVTVAARSLSGVGLTSDATRLAGQAALQTADARVSGA MAB_4292|M.abscessus_ATCC_1997 TWLRVLANHVDGEEVDSAARMLADTGLGWDATRLASQAALHANDPKVAAS MAV_0578|M.avium_104 LSLPLADAIACHAEALRAGNGEALLTVAAAYRAIG--DAAAAADAAAQAS TH_4413|M.thermoresistible__bu VDGPRVAVAARFADALHTGDGSGLRSIADEFEDMG--DMVAAADAAAHAA MUL_2876|M.ulcerans_Agy99 AARALQDADLDLRKIEPVERS----------------------------- . . Mflv_0277|M.gilvum_PYR-GCK MLQLARDLKATVA-ASDASVPSSATDTVAPPPAVPQRVSSTQLSEREREV Mvan_0620|M.vanbaalenii_PYR-1 MLQLARDLKDAVAGEAPVDLPDGAPPSAAASAGPSGRPAAAHLSDREREV MSMEG_0691|M.smegmatis_MC2_155 MLQLARDLKQSGA-ADDVSAPETPRAPVATQAGAP--AGSARLSDREREV Mb0346c|M.bovis_AF2122/97 MLQLARDLKLGNDFGEPPSGAGDTEPASGTPPAPRQPPAGSPLSDREREV Rv0339c|M.tuberculosis_H37Rv MLQLARDLKLGNDFGEPPSGAGDTEPASGTPPAPRQPPAGSPLSDREREV MMAR_0612|M.marinum_M MLQLARDLKLASGFDEPT----DAEPVAGAAPAPRQPPAGSPLSDREREV MAB_4292|M.abscessus_ATCC_1997 MLALARDLR----------SPSAAADGESTPSSAVHSPTSTRLSEREREV MAV_0578|M.avium_104 AAFVEGQQHQRGRYAAALAGELAEECGGLCTPALR-TPAGLKLSGRQRDV TH_4413|M.thermoresistible__bu IAHRRRGLRGSALACSAHAQGLAERCGGAHTPALRRAAEDLPLTDREREI MUL_2876|M.ulcerans_Agy99 --------------------------PAARSLAEVQTRVMAMLTRREVEV . *: *: :: Mflv_0277|M.gilvum_PYR-GCK AELLLQGLPYREIGSQLFISAKTVEHHVARIRRRLGAESRSEMLSMLRAA Mvan_0620|M.vanbaalenii_PYR-1 AELLLQGLPYRDIGAQLFISAKTVEHHVARIRRRLGAESRSELLSMLRAL MSMEG_0691|M.smegmatis_MC2_155 AELLLLGMPYRDIGNQLFISAKTVEHHVARIRRRLGAESRSEMLSMLRAM Mb0346c|M.bovis_AF2122/97 AELLLLGMPYRDIGARLFISAKTVEHHVARIRQRLGAGSRSEMLSMLRAM Rv0339c|M.tuberculosis_H37Rv AELLLLGMPYRDIGARLFISAKTVEHHVARIRQRLGAGSRSEMLSMLRAM MMAR_0612|M.marinum_M AELLLLGMPYRDIGAQLFISAKTVEHHVARIRRRLGAGSRSEMLSMLRAM MAB_4292|M.abscessus_ATCC_1997 AELLLRGLPYRDIGAQLFISAKTVEHHVARIRRRLGAESRSDMFSMLRAI MAV_0578|M.avium_104 IELAVAGLSNRQIAERLVMSVRTVEGHIYRACQRVGAQSRDELATIIRSR TH_4413|M.thermoresistible__bu VLLLGAGLTNREIADTLTLSVRTVENHIYKSMLKTGTSSRDELAALLPRS MUL_2876|M.ulcerans_Agy99 LRLMAAGRTNQQIADELVISAGTVKSHVKRVLRKLHATNRAEAASAYVRL * * . ::*. * :*. **: *: : : : .* : : Mflv_0277|M.gilvum_PYR-GCK LDTPASR---------- Mvan_0620|M.vanbaalenii_PYR-1 TDSPTRS---------- MSMEG_0691|M.smegmatis_MC2_155 FSPQG------------ Mb0346c|M.bovis_AF2122/97 LAPESLTADERR----- Rv0339c|M.tuberculosis_H37Rv LAPESLTADERR----- MMAR_0612|M.marinum_M LTAPG------------ MAB_4292|M.abscessus_ATCC_1997 LTP-------------- MAV_0578|M.avium_104 PAGRES----------- TH_4413|M.thermoresistible__bu PRPSDPRRAPRSPRRID MUL_2876|M.ulcerans_Agy99 ASVSEVG----------