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VLPAAREAIAAVDADPRAATKSLVTGGIGTGKTTLLAAMRTTFRSAGRQVLSRPPDAGTPGDGAGYALVV DDAHLLGDDDLDRLTDLAGDPASTVVIATQALMHRSRLQVLMTVLARENPEVALRPLTAAQVQEAATSAL GASVGPELTRLLVSVTGGFPFLVSAALSAIPDGAQSARQAAHFALIERLARLDGHLLDTLLVMTLSPGLG PDDVAAALRIPADEAVAAVDSARATALIDPAHTSQFLAAVHDGIAQIVGAARHHDVEMAVLDSQLALCTL TADLALRIADHGVRDDRLATALTDFAARVPDRPARAARLYRAATDAGTTAVRPALADALVLTGDCVTAGR LADDLLTSQDPDERAAAVRIAASIALHDGAARQAADLFAWLGPAPDAVVGAAETIAALAVGDAAAVRSTA QGPPSGPPTAVARSARAITEGLVMTLDQPYPAAIARLSQAIAVDAVHGVLPDTPAALVTLAALHGGDPVR ARSVIGRAVLADSRPDRADATFVTSRHRLLQGWAYMQDGQLAAAAAAIPADGDPRLHRRDALWAAALHTG IARRSGDTGAMQMHWRSAMDVLAESSADLFTVLPLGELWIAASRLRQVDQVRHSLDEVFGLLAALGDPLL WSIPLHWAGVHAGILANSPDAVAPHGAALTAAAPHAQFAKALAAAGRTWLRVLADRVDVAEVTAAARGLA LHGHTWDATRLAGQAALQTTDSRAAQAMLQLARDLKATVAASDASVPSSATDTVAPPPAVPQRVSSTQLS EREREVAELLLQGLPYREIGSQLFISAKTVEHHVARIRRRLGAESRSEMLSMLRAALDTPASR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0277 | - | - | 100% (833) | response regulator receiver protein |
| M. gilvum PYR-GCK | Mflv_1156 | - | 2e-17 | 23.88% (934) | regulatory protein, LuxR |
| M. gilvum PYR-GCK | Mflv_4479 | - | 8e-15 | 25.57% (876) | regulatory protein, LuxR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0346c | - | 0.0 | 55.89% (832) | transcriptional regulatory protein |
| M. tuberculosis H37Rv | Rv0339c | - | 0.0 | 55.89% (832) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_01753 | - | 9e-05 | 36.54% (52) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4292 | - | 1e-172 | 44.98% (816) | LuxR family transcriptional regulator |
| M. marinum M | MMAR_0612 | - | 0.0 | 54.40% (829) | transcriptional regulatory protein |
| M. avium 104 | MAV_0578 | - | 3e-15 | 24.61% (841) | transcriptional regulator, LuxR family protein |
| M. smegmatis MC2 155 | MSMEG_0691 | - | 0.0 | 61.16% (829) | putative transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_4413 | - | 2e-12 | 25.50% (647) | PUTATIVE putative response regulator receiver protein |
| M. ulcerans Agy99 | MUL_2876 | - | 9e-08 | 32.03% (153) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0620 | - | 0.0 | 66.87% (830) | response regulator receiver protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0346c|M.bovis_AF2122/97 ----------------------------------------MQHRGCKNRG
Rv0339c|M.tuberculosis_H37Rv ----------------------------------------MQHRGCKNRG
MMAR_0612|M.marinum_M -----------------------------------------MSEGHASRD
Mflv_0277|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0620|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0691|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4292|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0578|M.avium_104 -----------------------MIGGELLIGRDSELAAIRRALNGADHH
TH_4413|M.thermoresistible__bu --------------------------------------------------
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01753|M.leprae_Br4923 MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTDLHRGCTVTLFLGDVEG
Mb0346c|M.bovis_AF2122/97 QAYDASVTDSLTEVPPAARRALLELANAPTVPVKVLITGGIGTGKTTVLA
Rv0339c|M.tuberculosis_H37Rv QAYDASVTDSLTEVPPAARRALLELANAPTVPVKVLITGGIGTGKTTVLA
MMAR_0612|M.marinum_M ---DTSAPPDSAAVPAPARGLIDELASGGATSVKALIGGGIGTGKTTVLG
Mflv_0277|M.gilvum_PYR-GCK -------------MLPAAREAIAAVDADPRAATKSLVTGGIGTGKTTLLA
Mvan_0620|M.vanbaalenii_PYR-1 --MTTPAAPRLSDLPPAAREAVAAMEADPHAPVKLVVVGGAGSGKSTVLT
MSMEG_0691|M.smegmatis_MC2_155 --MANPAPEHAVDLPRAVQEMLAGVPSRP---AKLLVSGGIGTGKSTVLA
MAB_4292|M.abscessus_ATCC_1997 ------MSGTFDGIASAITAITGPLSAGH--AVKVLVNGTAGSGKTFVLS
MAV_0578|M.avium_104 RGVVIAGAAGVGKTWLARAALRRAGASGEQIKWIVGTQSAQALPLGAFIG
TH_4413|M.thermoresistible__bu --------------------------------------------------
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01753|M.leprae_Br4923 LAELSETQPDEAADAIARLDCVVSEAVAAHGGVQQVVQGVRGNFLATFAR
Mb0346c|M.bovis_AF2122/97 AARDTLRRSGLTVLACPPPDGEPPE---TALVIDD---------------
Rv0339c|M.tuberculosis_H37Rv AARDTLRRSGLTVLACPPPDGEPPE---TALVIDD---------------
MMAR_0612|M.marinum_M TVRDALRRAGVTVRAHPTKDCDPSE---VALVVDD---------------
Mflv_0277|M.gilvum_PYR-GCK AMRTTFRSAGRQVLSRPPDAGTPGDGAGYALVVDD---------------
Mvan_0620|M.vanbaalenii_PYR-1 AVRAVLRASDRPVRSRPRGGETAED---TVTVVDD---------------
MSMEG_0691|M.smegmatis_MC2_155 AVRATLREAGRTVLTRPP---RPDDDQGAVFVIDD---------------
MAB_4292|M.abscessus_ATCC_1997 RIREALGSAGTPAVNHVPEAAPGPN--TGPFVIDD---------------
MAV_0578|M.avium_104 LLGDAMSEPLTSVRRVIETFVARQRRGRVVVGVDD---------------
TH_4413|M.thermoresistible__bu --------------------------------------------------
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01753|M.leprae_Br4923 ASDATACALDLQLAPIVPVRFRIALHTGEVQISNDDVNNVVFMMVQAAGL
Mb0346c|M.bovis_AF2122/97 -------AQLLTDTELLRLTERVADSRLTVVAAAEAREHHR---------
Rv0339c|M.tuberculosis_H37Rv -------AQLLTDTELLRLTERVADSRLTVVAAAEAREHHR---------
MMAR_0612|M.marinum_M -------AHLLAEDELLRLAEWVADPRATVVVGAQLHQQHH---------
Mflv_0277|M.gilvum_PYR-GCK -------AHLLGDDDLDRLTDLAGDPASTVVIATQALMHRS---------
Mvan_0620|M.vanbaalenii_PYR-1 -------AHLLDRAELDQLTELVTDPTAGVVIATEPLAHHG---------
MSMEG_0691|M.smegmatis_MC2_155 -------AHHLADDEIDCLTERSTDPSSTVVVAAEPLAHRP---------
MAB_4292|M.abscessus_ATCC_1997 -------ADSLTDRQLETLRAVVENDPAAIIVVAAAPRRNP---------
MAV_0578|M.avium_104 -------AHLLDGLSALVVHQLAQSGGVRLVVTVRTGSHQPDAVTALWKD
TH_4413|M.thermoresistible__bu --------------------------------------------------
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01753|M.leprae_Br4923 LDLACGGQTVLSSITGDLVVDGLPADTWLVDLGSHLLRDLARPVRVMQLC
Mb0346c|M.bovis_AF2122/97 ------ALRALTMALERDRPRISLGPLPVAEH------------------
Rv0339c|M.tuberculosis_H37Rv ------ALRALTMALERDRPRISLGPLPVAEH------------------
MMAR_0612|M.marinum_M ------ALRALATAIERERPQISLGPLPVADQ------------------
Mflv_0277|M.gilvum_PYR-GCK ------RLQVLMTVLARENPEVALRPLTAAQVQEAATSALGASVGPELTR
Mvan_0620|M.vanbaalenii_PYR-1 ------PLRELVTALEREHAAVALGPLPPVEVSRIAAAALGLPAAPELVR
MSMEG_0691|M.smegmatis_MC2_155 ------VLRALATALERENPIVALGPMSTAEVGRLLTATLGSPPPPDTVR
MAB_4292|M.abscessus_ATCC_1997 ------ALRSLFQALERESPAITLGPVNATDIGRMS------PLAAPFAE
MAV_0578|M.avium_104 DLLTRLDLEPLSAAATREVIESTLGGPVDARCAARFRRLTGGNTLFLRQL
TH_4413|M.thermoresistible__bu ------------------VVRRSGG-------------------------
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01753|M.leprae_Br4923 HRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAAQIKELQELLTEKRLLT
Mb0346c|M.bovis_AF2122/97 -LRDCTAGLPFLIHAVSARAQA----------------------------
Rv0339c|M.tuberculosis_H37Rv -LRDCTAGLPFLIHAVSARAQA----------------------------
MMAR_0612|M.marinum_M -LRDSTAGVPFLVEAVSRGTGS----------------------------
Mflv_0277|M.gilvum_PYR-GCK LLVSVTGGFPFLVSAALSAIPDG---------------------------
Mvan_0620|M.vanbaalenii_PYR-1 ALLSATAGLPFLLRPALAAAGDG---------------------------
MSMEG_0691|M.smegmatis_MC2_155 AVLAVTAGLPFLVRAVATSAAE----------------------------
MAB_4292|M.abscessus_ATCC_1997 QIAAASGGVLALTAAAVERLGDPDP-------------------------
MAV_0578|M.avium_104 LSDQMAAGRMRRVAGVWMWDGDV---------------------------
TH_4413|M.thermoresistible__bu --------------------------------------------------
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01753|M.leprae_Br4923 LVGPGGVGKTRLALQVVARVADEFSGELSYFDLAPDTDHDIFPITVLDNL
Mb0346c|M.bovis_AF2122/97 --------------------------------------------------
Rv0339c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0612|M.marinum_M --------------------------------------------------
Mflv_0277|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0620|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0691|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4292|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0578|M.avium_104 --------------------------------------------------
TH_4413|M.thermoresistible__bu --------------------------------------------------
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01753|M.leprae_Br4923 RRCIGDRRMLMVLDNCEYLLDVCANVMTTLLGACPSLTILATSREPIGVA
Mb0346c|M.bovis_AF2122/97 ------------------------PAQAAKVALIERLRRLDEPTLDTLLM
Rv0339c|M.tuberculosis_H37Rv ------------------------PAQAAKVALIERLRRLDEPTLDTLLM
MMAR_0612|M.marinum_M ------------------------PVPAARFALIERLRRLDEPTLDALLI
Mflv_0277|M.gilvum_PYR-GCK ---------------------AQSARQAAHFALIERLARLDGHLLDTLLV
Mvan_0620|M.vanbaalenii_PYR-1 ---------------------VASMRQAARFGLIERLRGFDERLLDTLLV
MSMEG_0691|M.smegmatis_MC2_155 ------------------------PEEAARYALIERVRHLGEQTRDTLLL
MAB_4292|M.abscessus_ATCC_1997 ---------------------LQSALRAIDTRVDELLRRLSPMAQAAVLL
MAV_0578|M.avium_104 -----------------------AVSASLSDTVGRQLGRLTPPLALVVDT
TH_4413|M.thermoresistible__bu -------------------------APGLIALIEERIGLLAEPVGDVVDI
MUL_2876|M.ulcerans_Agy99 ------------------------------MGFSPRRAIPERTVGGVIDV
MLBr_01753|M.leprae_Br4923 GEVIWRVSMLSPADEAVELFTERAALVQPGFSVTDGNRQIVTEICQRLDG
. :
Mb0346c|M.bovis_AF2122/97 MSLTHELGV------------SDVAAALGISVTDARGLVDRAHASGLIES
Rv0339c|M.tuberculosis_H37Rv MSLTHELGV------------SDVAAALGISVTDARGLVDRAHASGLIES
MMAR_0612|M.marinum_M MSLTQESGT------------TDVAAALGVSTSDARQLVDRVHASGLVEP
Mflv_0277|M.gilvum_PYR-GCK MTLSPGLGP------------DDVAAALRIPADEAVAAVDSARATALIDP
Mvan_0620|M.vanbaalenii_PYR-1 SSLSFDLGP------------DDVAAALRLSSQEALTAVDRARASGLIEP
MSMEG_0691|M.smegmatis_MC2_155 TSLSLDLGP------------DDVAGALRVSGTDASVLVDRARAGGLVEP
MAB_4292|M.abscessus_ATCC_1997 MSLNPGIGA------------SDVAAALALP--DAADLVDEALASGLIAG
MAV_0578|M.avium_104 LSQCEPLPVD---------LLCDLASREDLVAAEAMGLVTVERTPRALMA
TH_4413|M.thermoresistible__bu LAVGEPVDLG---------LLTRLTDPAAVEEADVRGLIAIEDGDRALVR
MUL_2876|M.ulcerans_Agy99 VDMP------------------DPPAFPTLADDEHPGWASRPIRESDATR
MLBr_01753|M.leprae_Br4923 MPLAIELAAARIRTLSLTEIADGLDDRFRLLTGGARTAVRRQQTLRASMD
:
Mb0346c|M.bovis_AF2122/97 SHTAAFLQSVHDAIAQIVGNAHHHEVETSLLRSQLDIS--PVSAELALRL
Rv0339c|M.tuberculosis_H37Rv SHTAAFLQSVHDAIAQIVGNAHHHEVETSLLRSQLDIS--PVSAELALRL
MMAR_0612|M.marinum_M SHPPAFVQLVHEAVVHIVGNTHHHEVETSLLRSQLDIS--PMSQDLALRL
Mflv_0277|M.gilvum_PYR-GCK AHTSQFLAAVHDGIAQIVGAARHHDVEMAVLDSQLALC--TLTADLALRI
Mvan_0620|M.vanbaalenii_PYR-1 AHPLAFQRTLHDAVAQVVGAARHHDIEVSVLLSQLELS--TLTADLALRL
MSMEG_0691|M.smegmatis_MC2_155 AYDKRFLRLVHTSVAQIAGTSRHHDIEIALLHSQLEKA--TLSPELAVRL
MAB_4292|M.abscessus_ATCC_1997 PGHVAFAARVHGCAARLLGAARHLDLERSLLRTQLEMG--SVSADLALAL
MAV_0578|M.avium_104 RLAHPLFGELRRAGAGEMYLSTIRGRLATRLAQDQDAD-MQATVRRALLT
TH_4413|M.thermoresistible__bu -LAHPLYGEVRRRRAAVTRLRRLRGLVADELAQAADADDLAQVVRRTTLL
MUL_2876|M.ulcerans_Agy99 HYREAFGDCNVDP----------TDDPMAVVAEAIDVN---------AAA
MLBr_01753|M.leprae_Br4923 WSYALLTESERALFRRLSAISGTFDLKVAYAVGHDDLEEPDQVFDRLTML
:
Mb0346c|M.bovis_AF2122/97 AEHGLRDERLADILTRYAADTRDASVRCARLYRAAVHAGAKG--LTVRLA
Rv0339c|M.tuberculosis_H37Rv AEHGLRDERLADILTRYAADTRDASVRCARLYRAAVHAGAKG--LTVRLA
MMAR_0612|M.marinum_M AEHGLHGERLATALAGYASAARGEPAQTARLYRAAVAAGATG--LKSQLA
Mflv_0277|M.gilvum_PYR-GCK ADHGVRDDRLATALTDFAARVPDRPARAARLYRAATDAGTTA--VRPALA
Mvan_0620|M.vanbaalenii_PYR-1 AEHGLRDERLATALTDLAGRTRGHPARAARLYRAAAEAGASA--PGVRLA
MSMEG_0691|M.smegmatis_MC2_155 AEHGVRDDRLAAALTDHAVQVRGQPARAARLYRAAARAGSAA--LNARLA
MAB_4292|M.abscessus_ATCC_1997 VGHGLRDLEVARLLSNWATTESD-PLSAADLYRAALTAGAEPDPIRVPLA
MAV_0578|M.avium_104 LESDLDPQPELYLESARHAMTLLDLDLADRLANAAARAGAP--GAAGVRA
TH_4413|M.thermoresistible__bu LDSDRRPDVDLFVRAARGAARIGDLPLAERLSGAAVRAGATV-EAAIVHA
MUL_2876|M.ulcerans_Agy99 VRHALESQGDVHAVNALETLLDLSSLEREMIEDGAARRTLALLQVQEALS
MLBr_01753|M.leprae_Br4923 IDKSLVIVEGRQGGSRYRLLETVRQYAMKKLEESNEVDLVLARHRDHYMA
: . :
Mb0346c|M.bovis_AF2122/97 DALARTGDCTAAATLADDLLSS------------PDATERAAAVRVAASV
Rv0339c|M.tuberculosis_H37Rv DALARTGDCTAAATLADDLLSS------------PDATERAAAVRVAASV
MMAR_0612|M.marinum_M DALARTGDCAGAAELADELLGS------------ADSAQRAAAVRIAASV
Mflv_0277|M.gilvum_PYR-GCK DALVLTGDCVTAGRLADDLLTS------------QDPDERAAAVRIAASI
Mvan_0620|M.vanbaalenii_PYR-1 DALALTGDCGTAGRLADDLLTA------------PDPAERAAAVRIAASV
MSMEG_0691|M.smegmatis_MC2_155 DALALSGDCATAGRMADDLLSS------------DDPAERAAAVRIAASI
MAB_4292|M.abscessus_ATCC_1997 ESLARAGDLAAAAAQADEVLAS------------TDPAQRTAGVRVAAAI
MAV_0578|M.avium_104 MNLVLLGRGEQAEEALRAITDGADG---------DASDRHYWATVRAANL
TH_4413|M.thermoresistible__bu RALTWLGRGDQAETVLAAI---------------DVADHTRLAFMRASNM
MUL_2876|M.ulcerans_Agy99 KLRAVDDVAMIVDRAPRELVES-------------------CGFDRAVLF
MLBr_01753|M.leprae_Br4923 LGALLDTPGDIDHEQLVEQVETELDNLRSAFAWSRETGDIAGALQLASSL
. * .
Mb0346c|M.bovis_AF2122/97 AVHDGNTGHAAELFGWLGPHPDTMVSSAATIVFAANGDLATARATLRLKD
Rv0339c|M.tuberculosis_H37Rv AVHDGNTGHAAELFGWLGPHPDTMVSSAATIVFAANGDLATARATLRLKD
MMAR_0612|M.marinum_M AAHEGNAGQAAELFGWLGPYPDAVVGSSAAIVLAAVGDLQTARAALDVKD
Mflv_0277|M.gilvum_PYR-GCK ALHDGAARQAADLFAWLGPAPDAVVGAAETIAALAVGDAAAVRSTAQGPP
Mvan_0620|M.vanbaalenii_PYR-1 ALHDGGAEQAHSLFEWLGPVPDTVVAAAATIAAVAAGDAAAARSTAQMPA
MSMEG_0691|M.smegmatis_MC2_155 AMHDGSAAQAADLFRWLGPYPDAAVGSAGTVALLAAGDAEAARAALNTEL
MAB_4292|M.abscessus_ATCC_1997 ACHNGDSGQAAALYSWLGADMDGLTALSASPVFVGTGQLAKGRKSLEDNV
MAV_0578|M.avium_104 VWMLGRPADAALVLDGLAARPETPAQAAARCAVQACLDAVAARCQLAAER
TH_4413|M.thermoresistible__bu LWALSDPEGAKRLIGQAAAG--MPADQRAHLDAFCAVHAAAMGQPDEVFR
MUL_2876|M.ulcerans_Agy99 RVHEGRLVMESAYFGEDREGAEKMVAFAQSVAPLLDHMLIETQMIR----
MLBr_01753|M.leprae_Br4923 QPIWFGRGHMYEGLAWFDSIFEHKNIEHLVAPKEVLARAVANKVMLHAIL
Mb0346c|M.bovis_AF2122/97 AGPPTMAARCARNLAEGLLLTMDQPYPVAMAKLGQAIATEQSLSQVIPDS
Rv0339c|M.tuberculosis_H37Rv AGPPTMAARCARNLAEGLLLTMDQPYPVAMAKLGQAIATEQSLSQVIPDS
MMAR_0612|M.marinum_M TGPPTMAARAARGLADGLLLTMGQPYPVAMAKLGQAIAAEQPITEATPDS
Mflv_0277|M.gilvum_PYR-GCK SGPPTAVARSARAITEGLVMTLDQPYPAAIARLSQAIAVDAVHG-VLPDT
Mvan_0620|M.vanbaalenii_PYR-1 PGPPTSTARAASGLAAGLVMTLDQPYPAAVARLSQALGTDLGQAMALPDT
MSMEG_0691|M.smegmatis_MC2_155 SGPPTSAARAARSLAEGLVASLDQPFTTTVARLGQAVTADPHTDSVGPDT
MAB_4292|M.abscessus_ATCC_1997 GAPPTTSATAQRNAALGVIASVEGRGQEALSLLGQAVTQQPSTSSFIPDS
MAV_0578|M.avium_104 ARAALDSESLPD--FHAMMASLALIMAMGALGQVDDLTAVAEQALRRATT
TH_4413|M.thermoresistible__bu HAGAVVVDELPG--IIGAETAWALTLAAGEAGRTAEAVAAADTGYRLTAR
MUL_2876|M.ulcerans_Agy99 -------------------------------RHAPAIVRDARNDPRVNRP
MLBr_01753|M.leprae_Br4923 ASSPPDGSDLVTQAQQALTMAREIGDSAVLARALTACGFSSGYDTEVARP
Mb0346c|M.bovis_AF2122/97 PAALVTLAAIHAGD-----PVRARSVIGRAVRAG----------------
Rv0339c|M.tuberculosis_H37Rv PAALVTLAAIHAGD-----PVRARSVIGRAVRAG----------------
MMAR_0612|M.marinum_M PAALVTLAAIHGGD-----PVRARSVIGRAVRSG----------------
Mflv_0277|M.gilvum_PYR-GCK PAALVTLAALHGGD-----PVRARSVIGRAVLADSRPD--------RA--
Mvan_0620|M.vanbaalenii_PYR-1 PAALVTLAALHGGD-----PVRARSVVGRAVHTDGQRE--------SE--
MSMEG_0691|M.smegmatis_MC2_155 PAALVALAALHGGD-----SVRARSVIGRAVRTGAPGA--------ENGT
MAB_4292|M.abscessus_ATCC_1997 TVALAALTMLHSGD-----TARARSILTGAIRADR---------------
MAV_0578|M.avium_104 SFEASHMRFWFGAV-----YGRACRLTGRIDEFVS---------------
TH_4413|M.thermoresistible__bu FSDAAYTRFTLTDA-----HVTALILAGRIAAAVD---------------
MUL_2876|M.ulcerans_Agy99 IVDFSLTHSYVAAP-----VMPTGKMIG----------------------
MLBr_01753|M.leprae_Br4923 YFAEAVELARTQGDKWTLSQIRLWGVVGFCVSGDPVALRAAAEAADDLAQ
:
Mb0346c|M.bovis_AF2122/97 --ADPLFQRRHLLLSGWIKMQEGQLPSASADVAAASA-------------
Rv0339c|M.tuberculosis_H37Rv --ADPLFQRRHLLLSGWIKMQEGQLPSASADVAAASA-------------
MMAR_0612|M.marinum_M --TDQVFHQRHLLLSGWIKMQEGQLPSASADVAAACS-------------
Mflv_0277|M.gilvum_PYR-GCK --DATFVTSRHRLLQGWAYMQDGQLAAAAAAIPAD-G-------------
Mvan_0620|M.vanbaalenii_PYR-1 --DATFVTRRHRLLQGWAYMQDGQLHAASAAVRAA-G-------------
MSMEG_0691|M.smegmatis_MC2_155 PPPAPFWAARHRLLLGWVKMLDGQLTAAGADVSAVES-------------
MAB_4292|M.abscessus_ATCC_1997 --RHDVFGVRHRLLAAWIAMLSGDLSGAVQWLPGA---------------
MAV_0578|M.avium_104 --TARRLADSARDVPGLAYANLALLLGNAELARGAAA-------------
TH_4413|M.thermoresistible__bu --TATVLDRQVGDLPGGTALLARGVAGRAALAAGRLD-------------
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01753|M.leprae_Br4923 EIGDRFVSLQCRLLLSIAQLWQGDMDGAIVRSGEVVAGAEAAHDTVTRTF
Mb0346c|M.bovis_AF2122/97 -----GTHLHRRDALWAAALQTAISRRTGDIGALQQHWYAAMEALAEYSL
Rv0339c|M.tuberculosis_H37Rv -----GTHLHRRDALWAAALQTAISRRTGDIGALQQHWYAAMEALAEYSL
MMAR_0612|M.marinum_M -----GAPMHRRDALWAAALETAIARRSGDAGALQKHWNAAMEVLGEYSL
Mflv_0277|M.gilvum_PYR-GCK -----DPRLHRRDALWAAALHTGIARRSGDTGAMQMHWRSAMDVLAESSA
Mvan_0620|M.vanbaalenii_PYR-1 -----DPGPHRRDALWAAALQTAVARRSGDSGAMQKHWYSAMEVLAEYSI
MSMEG_0691|M.smegmatis_MC2_155 -----GPPLHRRDALWAAALRTAIARRSGDSGAIQRHWFAAMEVLAEYSI
MAB_4292|M.abscessus_ATCC_1997 -----QVELSRRDRLFAESLRTGIARRHGDTGPLRQHWQASMDALSAYSI
MAV_0578|M.avium_104 -----EAARLVQEALAGAQIHEVTSGLRPASY---FALAEAHGRLGHPAQ
TH_4413|M.thermoresistible__bu -----DAVAWLRDVVSVLFSADTAGGFYGFGYRYQHPYATALAVLGHTAA
MUL_2876|M.ulcerans_Agy99 --------FLHADRLYSGRIVDEIDR------------------------
MLBr_01753|M.leprae_Br4923 GLYVQTRALVHRDVSAALVTAGLVVEAAAELSGVYQGIGYAAMVFAALAM
:
Mb0346c|M.bovis_AF2122/97 DLFALLPLGELWVAAARMRQVDQLQHTLDQALTLLDSLGNPALWS-----
Rv0339c|M.tuberculosis_H37Rv DLFALLPLGELWVAAARMRQVDQLQHTLDQALTLLDSLGNPALWS-----
MMAR_0612|M.marinum_M DLFALLPLGELWVAAARNRQVDQLQHTLDQAFSLLNSLGNPVLWS-----
Mflv_0277|M.gilvum_PYR-GCK DLFTVLPLGELWIAASRLRQVDQVRHSLDEVFGLLAALGDPLLWS-----
Mvan_0620|M.vanbaalenii_PYR-1 DVFTVLPLGELWVAAARMRQVERLRHTLDEVFAMLVGLGDPVLWA-----
MSMEG_0691|M.smegmatis_MC2_155 DLYSLLPLGELWVAAARMRRIDRLEHPLAEAFGLLDALGKPVLWS-----
MAB_4292|M.abscessus_ATCC_1997 DLYTLLPVGELWVAAARLRTLDVMTHHLDRAFAVLAHLGDPIAWS-----
MAV_0578|M.avium_104 ANEAIAGARSCVPPDFLF-----MHTGLALATGWALAAGGQLREA-----
TH_4413|M.thermoresistible__bu AATALATLDEREFPSWRY-----LDHERTIALAWLRAAQGAVSTS-----
MUL_2876|M.ulcerans_Agy99 ----------------------------DTVWAFAEGFGYAYERT-----
MLBr_01753|M.leprae_Br4923 GDVAAAVEASEACRPHLGADHGLVAIHLELMAAVALARGDVIVARRLADN
Mb0346c|M.bovis_AF2122/97 ----------NSLHWAGVHAGILANSPESVAPHGQALGAMVAHSTLAQAL
Rv0339c|M.tuberculosis_H37Rv ----------NSLHWAGVHAGILANSPESVAPHGQALGAMVAHSTLAQAL
MMAR_0612|M.marinum_M ----------NSLHWAGVHAGILANSPGAVAPHGQALGAAAAGNALAHAL
Mflv_0277|M.gilvum_PYR-GCK ----------IPLHWAGVHAGILANSPDAVAPHGAALTAAAPHAQFAKAL
Mvan_0620|M.vanbaalenii_PYR-1 ----------VPLHWAGVHAGILANSPDSVAPHGQALTAAAPHSSFARAL
MSMEG_0691|M.smegmatis_MC2_155 ----------MPLHWAGVHAGILANSPGAVAPHGQALTAAAGHSPFARAL
MAB_4292|M.abscessus_ATCC_1997 ----------APLRWAGVHAAILTNSPETLAPHGQALAAGAGSSTYARIL
MAV_0578|M.avium_104 ----------VATAQAAARLARDRGQPTHELACIQAAAQWGDAAGAVRAR
TH_4413|M.thermoresistible__bu ----------IQRLRAEAESARTAGRFAVELLCLQTAVQFGDRTCGPRLH
MUL_2876|M.ulcerans_Agy99 ----------VLLERMRRQHAEVRS-----------------------AL
MLBr_01753|M.leprae_Br4923 SVSATTGWHQMAALTTRARIAMAQGEPELARADIHAALACGADIQASLGI
. . .
Mb0346c|M.bovis_AF2122/97 SDAGRTWLRVLAENVDADEVTAAARSLSHVGLTSDATRLAGQAALQTSDA
Rv0339c|M.tuberculosis_H37Rv SDAGRTWLRVLAENVDADEVTAAARSLSHVGLTSDATRLAGQAALQTSDA
MMAR_0612|M.marinum_M SVAGRTWLRVLADQVDVDEVTVAARSLSGVGLTSDATRLAGQAALQTADA
Mflv_0277|M.gilvum_PYR-GCK AAAGRTWLRVLADRVDVAEVTAAARGLALHGHTWDATRLAGQAALQTTDS
Mvan_0620|M.vanbaalenii_PYR-1 AAAGRTWLKVLANQVDADEVSSAARGLAQYGHTWDATRLAGQAALQTTDP
MSMEG_0691|M.smegmatis_MC2_155 AGAGRTWLRVLANHVDVDEVAAAARGLAQFGLTWDATRLASQAALQTSDA
MAB_4292|M.abscessus_ATCC_1997 ATAGRTWLRVLANHVDGEEVDSAARMLADTGLGWDATRLASQAALHANDP
MAV_0578|M.avium_104 ALADALSLPLADAIACHAEALRAGNGEALLTVAAAYRAIG--DAAAAADA
TH_4413|M.thermoresistible__bu QLEDRVDGPRVAVAARFADALHTGDGSGLRSIADEFEDMG--DMVAAADA
MUL_2876|M.ulcerans_Agy99 ASADEAARALQDADLDLRKIEPVERS------------------------
MLBr_01753|M.leprae_Br4923 SDSMELLAELISQGDNHRQAGRLFGAASAQREKTGEVRFKVWDAGYESAV
.
Mb0346c|M.bovis_AF2122/97 RVSGAMLQLARDLKLGNDFGEPPSGAGDTEPASGTPPAPRQPPAGSPLSD
Rv0339c|M.tuberculosis_H37Rv RVSGAMLQLARDLKLGNDFGEPPSGAGDTEPASGTPPAPRQPPAGSPLSD
MMAR_0612|M.marinum_M RVSGAMLQLARDLKLASGFDEPT----DAEPVAGAAPAPRQPPAGSPLSD
Mflv_0277|M.gilvum_PYR-GCK RAAQAMLQLARDLKATVA-ASDASVPSSATDTVAPPPAVPQRVSSTQLSE
Mvan_0620|M.vanbaalenii_PYR-1 RVSQAMLQLARDLKDAVAGEAPVDLPDGAPPSAAASAGPSGRPAAAHLSD
MSMEG_0691|M.smegmatis_MC2_155 RVSQAMLQLARDLKQSGA-ADDVSAPETPRAPVATQAGAP--AGSARLSD
MAB_4292|M.abscessus_ATCC_1997 KVAASMLALARDLR----------SPSAAADGESTPSSAVHSPTSTRLSE
MAV_0578|M.avium_104 AAQASAAFVEGQQHQRGRYAAALAGELAEECGGLCTPALR-TPAGLKLSG
TH_4413|M.thermoresistible__bu AAHAAIAHRRRGLRGSALACSAHAQGLAERCGGAHTPALRRAAEDLPLTD
MUL_2876|M.ulcerans_Agy99 -------------------------------PAARSLAEVQTRVMAMLTR
MLBr_01753|M.leprae_Br4923 AVLRGAMGCKDFDSAWAEGAAMPIDDAITYAQRGRGNRKRPTTGWESLTP
*:
Mb0346c|M.bovis_AF2122/97 REREVAELLLLGMPYRDIGARLFISAKTVEHHVARIRQRLGAGSRSEMLS
Rv0339c|M.tuberculosis_H37Rv REREVAELLLLGMPYRDIGARLFISAKTVEHHVARIRQRLGAGSRSEMLS
MMAR_0612|M.marinum_M REREVAELLLLGMPYRDIGAQLFISAKTVEHHVARIRRRLGAGSRSEMLS
Mflv_0277|M.gilvum_PYR-GCK REREVAELLLQGLPYREIGSQLFISAKTVEHHVARIRRRLGAESRSEMLS
Mvan_0620|M.vanbaalenii_PYR-1 REREVAELLLQGLPYRDIGAQLFISAKTVEHHVARIRRRLGAESRSELLS
MSMEG_0691|M.smegmatis_MC2_155 REREVAELLLLGMPYRDIGNQLFISAKTVEHHVARIRRRLGAESRSEMLS
MAB_4292|M.abscessus_ATCC_1997 REREVAELLLRGLPYRDIGAQLFISAKTVEHHVARIRRRLGAESRSDMFS
MAV_0578|M.avium_104 RQRDVIELAVAGLSNRQIAERLVMSVRTVEGHIYRACQRVGAQSRDELAT
TH_4413|M.thermoresistible__bu REREIVLLLGAGLTNREIADTLTLSVRTVENHIYKSMLKTGTSSRDELAA
MUL_2876|M.ulcerans_Agy99 REVEVLRLMAAGRTNQQIADELVISAGTVKSHVKRVLRKLHATNRAEAAS
MLBr_01753|M.leprae_Br4923 AEHNVIRLVSEGLDTKDIAARLFVSVRTVHTHLTRIYSKLGLTSRVQLVQ
: :: * * ::*. * :*. **. *: : : .* :
Mb0346c|M.bovis_AF2122/97 MLRAMLAPESLTADERR-----
Rv0339c|M.tuberculosis_H37Rv MLRAMLAPESLTADERR-----
MMAR_0612|M.marinum_M MLRAMLTAPG------------
Mflv_0277|M.gilvum_PYR-GCK MLRAALDTPASR----------
Mvan_0620|M.vanbaalenii_PYR-1 MLRALTDSPTRS----------
MSMEG_0691|M.smegmatis_MC2_155 MLRAMFSPQG------------
MAB_4292|M.abscessus_ATCC_1997 MLRAILTP--------------
MAV_0578|M.avium_104 IIRSRPAGRES-----------
TH_4413|M.thermoresistible__bu LLPRSPRPSDPRRAPRSPRRID
MUL_2876|M.ulcerans_Agy99 AYVRLASVSEVG----------
MLBr_01753|M.leprae_Br4923 EAARHN----------------