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MTTATTSPVHAYQGVSDTEFSEWEQVAARVAGELSATALTRDRANQNPIAEIELLRRYGLLSFATAREFG GAGGSLVQALQLGRIIAAADGSIGQLLVYHYSNGVWTYILGSPTQREYISRGVGGHGWFQGSVSNPRDPG ITVTRTEEGYRVNGKRTFATGVAVADLITVLLYEAEPINAIIPSERDGLRFNDDWDNLGQRLTASGSVEF DNVLLRHDEVLTGLDEYSGLDGSRERRDGLRALFSQLIFVHLYLGIAEGALAAGVAYIRDKGRPWPEAHS TDVTEDPYHQQLLGRLSAGIAAGVALADSATKEFEQALAFGEAPTEAQWGALAIRVDQAKSVATEISLDV THNIYQATGARSTANSVGLDIYWRNARTHTTHDPLPYRQREIGRHLLTDQWPSPRSLNGLGRLAETTQGK KP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4123 | - | - | 100% (422) | monooxygenase |
| M. abscessus ATCC 19977 | MAB_1422c | - | 7e-31 | 28.83% (385) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0075 | - | 5e-09 | 22.54% (386) | putative hydroxylase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3121c | - | 1e-11 | 24.43% (393) | hypothetical protein Mb3121c |
| M. gilvum PYR-GCK | Mflv_4548 | - | 2e-13 | 22.93% (375) | acyl-CoA dehydrogenase type 2 |
| M. tuberculosis H37Rv | Rv3094c | - | 1e-11 | 24.43% (393) | hypothetical protein Rv3094c |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_1556 | - | 2e-11 | 24.68% (385) | dehydrogenase |
| M. avium 104 | MAV_3806 | - | 7e-34 | 38.65% (207) | dibenzothiophene desulfurization enzyme C |
| M. smegmatis MC2 155 | MSMEG_4592 | - | 4e-36 | 31.44% (388) | acyl-CoA dehydrogenase family protein |
| M. thermoresistible (build 8) | TH_3393 | - | 6e-36 | 31.22% (394) | PUTATIVE Acyl-CoA dehydrogenase, type 2, C-terminal domain |
| M. ulcerans Agy99 | MUL_3474 | - | 8e-10 | 24.18% (397) | dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_3173 | - | 1e-36 | 29.23% (390) | acyl-CoA dehydrogenase type 2 |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_4123|M.abscessus_ATCC_1997 ------MTTATTSPVHAYQGVSDTEFSEWEQVAARVAGELSATALTRDRA
MAV_3806|M.avium_104 --------------------------------------------------
MSMEG_4592|M.smegmatis_MC2_155 ------------MIVPAPELRTDLSAEQFLDDLAGTAAVIAGSAAERDAE
TH_3393|M.thermoresistible__bu -------------VTEPLTMARIVDTAEALAVAARLSGSFAAEASTRDAE
Mvan_3173|M.vanbaalenii_PYR-1 ---------MATDITDRIPDTLLRTPADALAAAEEVAEAIAAGSAERERA
Mb3121c|M.bovis_AF2122/97 -----------MNQ----------SETEIEILAEKIARWARARSAEIERD
Rv3094c|M.tuberculosis_H37Rv -----------MNQ----------SETEIEILAEKIARWARARSAEIERD
MMAR_1556|M.marinum_M -----------MNQPDLSAAPLRRADSEMENLAEKIALTAREMSAEIDRD
MUL_3474|M.ulcerans_Agy99 MTEPPSLPGVLMNQPDLSAAPLRRADSEMEDLAEKIALTAREMSAEIDRD
Mflv_4548|M.gilvum_PYR-GCK ------------------------MSERVLDRLNELAGQFKEQAVEAEKL
MAB_4123|M.abscessus_ATCC_1997 NQNPIAEIELLRRYGLLSFATAREFGGAGGSLVQALQLGRIIAAADGSIG
MAV_3806|M.avium_104 --------------------------------------------------
MSMEG_4592|M.smegmatis_MC2_155 RRYPTAEYDALRDVGFWRLTVPREYGGLGFGYQTLMSAVITVAAADGSLG
TH_3393|M.thermoresistible__bu RLLPYEQVCELKRSGLLTLSVPAEHGGLDVPATVLAEVFRLLAHGDPSVA
Mvan_3173|M.vanbaalenii_PYR-1 GAVLTPQLRLVAESGLLGISVPTAHGGPGLPASTVVEVLRRLARADGAVG
Mb3121c|M.bovis_AF2122/97 RRLPDELVTRLREAGLLRATMPREVAAPELAPGRALRCAEAVARGDASAG
Rv3094c|M.tuberculosis_H37Rv RRLPDELVTRLREAGLLRATMPREVAAPELAPGRALRCAEAVARGDASAG
MMAR_1556|M.marinum_M RRLPDELVARLGEAGLLRATMPREVQAAELAPGPALRCAEAVARGDASAG
MUL_3474|M.ulcerans_Agy99 RRLPDELVARLGEAGLLRATMPREVQAAELAPGPALRCAEAVARGDASAG
Mflv_4548|M.gilvum_PYR-GCK GKLPDATVKSMKSIGSIRLLQPKKHGGLEVHPREFAETVMATAALDPAAG
MAB_4123|M.abscessus_ATCC_1997 QLLVYHYSNGVWTYILGSPTQREYISRGVGGHGWFQGSVSNPRDPGITVT
MAV_3806|M.avium_104 --------------------------------------------------
MSMEG_4592|M.smegmatis_MC2_155 QLPQNHFNTLERIALAGSGDLRARVFGRVAEGAVLGNATAEPRERPPGEN
TH_3393|M.thermoresistible__bu QIPHSHFTFLEVLRLQGTERQRGFFYGLVLEGALFANAQSERGPHPIDVD
Mvan_3173|M.vanbaalenii_PYR-1 QLLLSHFVVAQAISGLGHTQPAPRIYADLLAGAQLGNASAERGTAHALDR
Mb3121c|M.bovis_AF2122/97 WCVSIAITSALLVAYLPARSREEMFGGGRGVAAGVWAPRGTARSVDGG--
Rv3094c|M.tuberculosis_H37Rv WCVSIAITSALLVAYLPARSREEMFGGGRGVAAGVWAPRGTARSVDGG--
MMAR_1556|M.marinum_M WCVSIAITSALLVAYLPASSRDEMFGAGRSVAAGVWAPRGKAKSVDGG--
MUL_3474|M.ulcerans_Agy99 WCVSIAITSALLVAYLPASSRDEMFGAGRSVAAGVWAPRGKAKSVDGG--
Mflv_4548|M.gilvum_PYR-GCK WVNGVVGVHPYQLAYADPKVGEEIWADDIDTWVASPYAPQGVAVPTDGG-
MAB_4123|M.abscessus_ATCC_1997 RTEEG------YRVNGKRTFATGVAVADLITVLLYEAEP-----------
MAV_3806|M.avium_104 --------------------------------------------------
MSMEG_4592|M.smegmatis_MC2_155 TTTLRRNGK-TYCLTGRKVYATGALLGDIIAVQARD---------ESGEL
TH_3393|M.thermoresistible__bu TTVLLRRGAGDYLLTGRKFYSTGALFADWIVVRASVPADAADAPTAATPK
Mvan_3173|M.vanbaalenii_PYR-1 RTTVTRRDG-HWVLNGTKYYATGTLGATWIAVAARIEG------RENGDT
Mb3121c|M.bovis_AF2122/97 -----------VVVSGRWPFCSGINHADIMFAGCFVDDR----------Q
Rv3094c|M.tuberculosis_H37Rv -----------VVVSGRWPFCSGINHADIMFAGCFVDDR----------Q
MMAR_1556|M.marinum_M -----------VVVSGRWPFCSGINHADMMFAGCFVEGQ----------P
MUL_3474|M.ulcerans_Agy99 -----------VVVSGRWPFCSGINHADMMFAGCFVEGQ----------P
Mflv_4548|M.gilvum_PYR-GCK -----------YIFTGRWQFSSGTDACDWIILGAMVGDAKG---VPLMPP
MAB_4123|M.abscessus_ATCC_1997 INAIIPSERDGLRF-NDDWDNLGQRLTASGSVEFDNVLLRHDEVLTGLDE
MAV_3806|M.avium_104 -----------------------MRRTDSGTTEFHNVAVRPDEVLG--KP
MSMEG_4592|M.smegmatis_MC2_155 VTALVDRYAHGVTI-VDDWSGFGQRTTASGTAVFDGVEVDETGVLR----
TH_3393|M.thermoresistible__bu AVAFVPRHAPGLTV-IDDWDGMGQRTTASGSVTLDEVRVPADHVVP----
Mvan_3173|M.vanbaalenii_PYR-1 ATAFVRPDQEGVTLDLESWSAFGQRGTASGEVRLNNVVVDDDLLID----
Mb3121c|M.bovis_AF2122/97 VPSVVALNKDELQV-LDTWHTLGLRGTGSHDCVADDVFVPADRVFS---V
Rv3094c|M.tuberculosis_H37Rv VPSVVALNKDELQV-LDTWHTLGLRGTGSHDCVADDVFVPADRVFS---V
MMAR_1556|M.marinum_M VPSVVALPKDDLRA-LDTWHTLGLRGTGSHDCVAEEVFVPADRVFS---V
MUL_3474|M.ulcerans_Agy99 VPSVVALPKDDLRA-LDTWHTLGLCGTGSHDCVAEEVFVPADRVFS---V
Mflv_4548|M.gilvum_PYR-GCK QMLHMILPRKDYQIVDDSWDVVGLRGTGSKDVIVDGAFVPTYRTMDGMKV
* * . . : .
MAB_4123|M.abscessus_ATCC_1997 YSGLDGSRER-RDGLRAL----FSQLIFVHLYLGIAEGALAAGVAYIRDK
MAV_3806|M.avium_104 NAILEAFLASGRGSLFGP----IVQLVFSSVYLGIARGALETAREYTRTQ
MSMEG_4592|M.smegmatis_MC2_155 -FGSDP----HPRYRASA----QSQLLHCAIDTGIAQGAFEAAVRLAHQV
TH_3393|M.thermoresistible__bu -FTPIF----RRPTVYGA----RAQLWHAALDVGIATAALEEGVRLAARA
Mvan_3173|M.vanbaalenii_PYR-1 -EGPPPDPITADPSVLGA----FDQALHAAIDIGIARAALEDGAVFVRTR
Mb3121c|M.bovis_AF2122/97 FDGPIVDRPLYRFPVFG-----FFALSIGAAALGNARAAIDDLVELAGGK
Rv3094c|M.tuberculosis_H37Rv FDGPIVDRPLYRFPVFG-----FFALSIGAAALGNARAAIDDLVELAGGK
MMAR_1556|M.marinum_M FDGPSIDRPLYRFPVFG-----FFALSIGAAALGNARAAIDDLVELAGDK
MUL_3474|M.ulcerans_Agy99 FDGPTIDRPLYRFPVFG-----FFALSIGAAALGNARAAIDDLVELAGDK
Mflv_4548|M.gilvum_PYR-GCK MDGSAQIEAGMTEPLYKMPWSTMFPLGISSATIGICEGALAAHLDYQRER
* . .*:
MAB_4123|M.abscessus_ATCC_1997 GRP---WPEAHSTDVTEDPYHQQLLGRLSAGIAAGVALADSATKEFEQAL
MAV_3806|M.avium_104 ARP---WTPAGVTQAVEDPYTIRSYGEFGIQLQAADAAAREAAQLLQAAW
MSMEG_4592|M.smegmatis_MC2_155 HG----GRGSGAVEFTDDVLGVSRLGELWITVEGARAIVTHAAQALDALT
TH_3393|M.thermoresistible__bu RP----HFESGAPVATDDPTLIQSAGEVAVTVRAAQALLGEAARAVDAAT
Mvan_3173|M.vanbaalenii_PYR-1 SRPWKEALDAGIERADQEPHVVRRFGELTARLYALEALLARGTALIDEAY
Mb3121c|M.bovis_AF2122/97 KG------LGSTRTLAERSATQAAAATAESALGAARALFYEVIEAAWQVS
Rv3094c|M.tuberculosis_H37Rv KG------LGSTRTLAERSATQAAAATAESALGAARALFYEVIEAAWQVS
MMAR_1556|M.marinum_M KG------LGAKRTLAERSATQTAVATAEAALGAARALFYEAIDSAWQAS
MUL_3474|M.ulcerans_Agy99 KG------LGAKRTLAERSATQTAVATAEAALGAARALFYEAIDSAWQAS
Mflv_4548|M.gilvum_PYR-GCK VG-------ANGTAIKDDPYVMYAIGDAAAEIEASRNTLLSNVDRVYDIV
. : . : .
MAB_4123|M.abscessus_ATCC_1997 AFGE------APTEAQWGALAIRVDQAKSVATEISLDVTHNIYQATGARS
MAV_3806|M.avium_104 DKGD------ALTSQERGELMVQISGVKAIATQAALDVTSRIFEVIGARG
MSMEG_4592|M.smegmatis_MC2_155 DT---------DPLDKVLDAFYRVAAAKSISTEAALTVTAALIDIGGASS
TH_3393|M.thermoresistible__bu AD---------LTEDTAAAASIAVATAKVAAERAALRASTALFELGGTRS
Mvan_3173|M.vanbaalenii_PYR-1 AAP-------EVTRDAAAQASLTVAAAKALAQQDAVEIAGAIFELTGTSG
Mb3121c|M.bovis_AF2122/97 HDAE----------AVPVTMRNRLRLAATHAVRTSADVVRSMYDLAGGTA
Rv3094c|M.tuberculosis_H37Rv HDAE----------AVPVTMRNRLRLAATHAVRTSADVVRSMYDLAGGTA
MMAR_1556|M.marinum_M HNPD----------PVPVALRNRLRLAATHAARTSADVVRIMYDLAGSSA
MUL_3474|M.ulcerans_Agy99 HNPDPVPVPVPVPVPVPVALRNRLRLAATHAARTSADVVRTMYDLAGSSA
Mflv_4548|M.gilvum_PYR-GCK DSGR----------EVTFETRAAVRRSQIKAVWRAVAAVDQIFARSGGNA
: : : : * .
MAB_4123|M.abscessus_ATCC_1997 TANSVGLDIYWRNARTHTTHDPLPYRQREIGRHLLTDQWPSPRSLNGLGR
MAV_3806|M.avium_104 THPKYGFDRFWRNIRTHTLHDPVSYKIAEVGNYVLNQRYPIP----GFTS
MSMEG_4592|M.smegmatis_MC2_155 TRTELRLDRFWRDARTHTVHDAVRWKPYSIGRRLLTGDVADAWSIAHPFT
TH_3393|M.thermoresistible__bu ATVSANLSRFWRDARTHTLHDPTRWKLHHIGRYLLSGTRPPRHGQL----
Mvan_3173|M.vanbaalenii_PYR-1 TDGAVNLDRHWRNVRVHSLHDPARWKYVHLGNHTLHDTRPPRLGLIL---
Mb3121c|M.bovis_AF2122/97 IYDNAPLQRRFRDAFTATAHFQVNEASRELPGRVLLDQPADVSML-----
Rv3094c|M.tuberculosis_H37Rv IYDNAPLQRRFRDAFTATAHFQVNEASRELPGRVLLDQPADVSML-----
MMAR_1556|M.marinum_M IYDGSPLQRRFRDAFTATAHFQVNEASRELPGRVLLGQHCDTSML-----
MUL_3474|M.ulcerans_Agy99 IYDGSPLQRRFRDAFTATAHFQVNEASRELPGRVLLGQHCDTSML-----
Mflv_4548|M.gilvum_PYR-GCK LRMDKPLQRYWRDAHAGVAHAIHVPGTVYHASALSSLGVDPQGPLRAMI-
:. :*: . *
MAB_4123|M.abscessus_ATCC_1997 LAETTQGKKP---
MAV_3806|M.avium_104 -------------
MSMEG_4592|M.smegmatis_MC2_155 PVDDLVHLASTRA
TH_3393|M.thermoresistible__bu -------------
Mvan_3173|M.vanbaalenii_PYR-1 -------------
Mb3121c|M.bovis_AF2122/97 -------------
Rv3094c|M.tuberculosis_H37Rv -------------
MMAR_1556|M.marinum_M -------------
MUL_3474|M.ulcerans_Agy99 -------------
Mflv_4548|M.gilvum_PYR-GCK -------------