For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MIVPAPELRTDLSAEQFLDDLAGTAAVIAGSAAERDAERRYPTAEYDALRDVGFWRLTVPREYGGLGFGY QTLMSAVITVAAADGSLGQLPQNHFNTLERIALAGSGDLRARVFGRVAEGAVLGNATAEPRERPPGENTT TLRRNGKTYCLTGRKVYATGALLGDIIAVQARDESGELVTALVDRYAHGVTIVDDWSGFGQRTTASGTAV FDGVEVDETGVLRFGSDPHPRYRASAQSQLLHCAIDTGIAQGAFEAAVRLAHQVHGGRGSGAVEFTDDVL GVSRLGELWITVEGARAIVTHAAQALDALTDTDPLDKVLDAFYRVAAAKSISTEAALTVTAALIDIGGAS STRTELRLDRFWRDARTHTVHDAVRWKPYSIGRRLLTGDVADAWSIAHPFTPVDDLVHLASTRA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4592 | - | - | 100% (414) | acyl-CoA dehydrogenase family protein |
| M. smegmatis MC2 155 | MSMEG_2650 | - | 6e-68 | 40.26% (385) | acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_4097 | - | 5e-43 | 33.24% (376) | acyl-CoA dehydrogenase domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3302c | fadE25 | 5e-15 | 25.82% (364) | acyl-CoA dehydrogenase FADE25 |
| M. gilvum PYR-GCK | Mflv_4367 | - | 4e-15 | 23.82% (382) | butyryl-CoA dehydrogenase |
| M. tuberculosis H37Rv | Rv3274c | fadE25 | 5e-15 | 25.82% (364) | acyl-CoA dehydrogenase FADE25 |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 3e-14 | 25.76% (361) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_1422c | - | 2e-41 | 32.55% (381) | putative acyl-CoA dehydrogenase |
| M. marinum M | MMAR_1262 | fadE25 | 2e-15 | 24.65% (357) | acyl-CoA dehydrogenase FadE25 |
| M. avium 104 | MAV_3422 | - | 7e-34 | 31.79% (390) | acyl-CoA dehydrogenase domain-containing protein |
| M. thermoresistible (build 8) | TH_3393 | - | 8e-65 | 40.81% (370) | PUTATIVE Acyl-CoA dehydrogenase, type 2, C-terminal domain |
| M. ulcerans Agy99 | MUL_2626 | fadE25 | 4e-15 | 24.65% (357) | acyl-CoA dehydrogenase FadE25 |
| M. vanbaalenii PYR-1 | Mvan_3173 | - | 2e-43 | 32.16% (398) | acyl-CoA dehydrogenase type 2 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1262|M.marinum_M MAGWAGNPSFDLFQLPEEHQELRAAIRALAEKEIAPHAADVDENSRFPQE
MUL_2626|M.ulcerans_Agy99 MAGWAGNPSFDLFQLPEEHQELRAAIRALAEKEIAPHAADVDENSRFPQE
Mb3302c|M.bovis_AF2122/97 MVGWAGNPSFDLFKLPEEHDEMRSAIRALAEKEIAPHAAEVDEKARFPEE
Rv3274c|M.tuberculosis_H37Rv MVGWAGNPSFDLFKLPEEHDEMRSAIRALAEKEIAPHAAEVDEKARFPEE
MLBr_00737|M.leprae_Br4923 MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE
Mflv_4367|M.gilvum_PYR-GCK MSRLAQT-----LGLTEFQTEIVSTVRQFVDKEVIPTAQELEHADTYPQA
MSMEG_4592|M.smegmatis_MC2_155 ----MIVPAPELRTDLSAEQFLDDLAGTAAVIAGSAAERDAER--RYPTA
TH_3393|M.thermoresistible__bu -----VTEPLTMARIVDTAEALAVAARLSGSFAAEASTRDAER--LLPYE
Mvan_3173|M.vanbaalenii_PYR-1 -MATDITDRIPDTLLRTPADALAAAEEVAEAIAAGSAERERAG--AVLTP
MAB_1422c|M.abscessus_ATCC_199 ------MTSAPSVLEIRALPGTDTYRNLLAQVAEGARDRDLD--DENPFD
MAV_3422|M.avium_104 ------MPVAFHRQDT--PAGAAAVQPVLAEIAADYRLRLADGGTEPPLR
MMAR_1262|M.marinum_M ALDALNASGFNAVHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN
MUL_2626|M.ulcerans_Agy99 ALDALNASGFNALHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN
Mb3302c|M.bovis_AF2122/97 ALVALNSSGFNAVHIPEEYGGQGADSVATCIVIEEVARVDASASLIPAVN
Rv3274c|M.tuberculosis_H37Rv ALVALNSSGFNAVHIPEEYGGQGADSVATCIVIEEVARVDASASLIPAVN
MLBr_00737|M.leprae_Br4923 ALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN
Mflv_4367|M.gilvum_PYR-GCK IVDAMREMGLFGLMIPEEYGGLGESLLTYALCVEELARGWMSVSGVINTH
MSMEG_4592|M.smegmatis_MC2_155 EYDALRDVGFWRLTVPREYGGLGFGYQTLMSAVITVAAADGSLGQLPQNH
TH_3393|M.thermoresistible__bu QVCELKRSGLLTLSVPAEHGGLDVPATVLAEVFRLLAHGDPSVAQIPHSH
Mvan_3173|M.vanbaalenii_PYR-1 QLRLVAESGLLGISVPTAHGGPGLPASTVVEVLRRLARADGAVGQLLLSH
MAB_1422c|M.abscessus_ATCC_199 QVRLLKEAGFGRLRIPTELGGAGLSVRQLFSAIIDVAQADPIVAHIFRTH
MAV_3422|M.avium_104 GLKLVRDHRLGALRLARELGGAGYTAPEFFDYLVALAAADPDLAHILRIH
: : : :. ** . . :* . : :
MMAR_1262|M.marinum_M KLGTMGLILRGSDDLKKQVLPSLADGAAMASYALSEREAGSDAGAMRTRA
MUL_2626|M.ulcerans_Agy99 KLGTMGLILRGSDELKKQVLPSLADGAAMASYALSEREAGSDAGAMRTRA
Mb3302c|M.bovis_AF2122/97 KLGTMGLILRGSEELKKQVLPALAAEGAMASYALSEREAGSDAASMRTRA
Rv3274c|M.tuberculosis_H37Rv KLGTMGLILRGSEELKKQVLPALAAEGAMASYALSEREAGSDAASMRTRA
MLBr_00737|M.leprae_Br4923 KLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMRTRA
Mflv_4367|M.gilvum_PYR-GCK FIVAYMIRQHGTDAQKSHYLPRMATGETRGAFSMSEPELGSDVAAIRTRA
MSMEG_4592|M.smegmatis_MC2_155 FNTLERIALAGSGDLRARVFGRVAEGAVLGNATAEPRERPPG-ENTTTLR
TH_3393|M.thermoresistible__bu FTFLEVLRLQGTERQRGFFYGLVLEGALFANAQSERGPHPID-VDTTVLL
Mvan_3173|M.vanbaalenii_PYR-1 FVVAQAISGLGHTQPAPRIYADLLAGAQLGNASAERGTAHAL-DRRTTVT
MAB_1422c|M.abscessus_ATCC_199 FWFVEERLRTLADPVSAAWLTKVNEGNLFANAFSEKGSLAVGSLVFNTRL
MAV_3422|M.avium_104 YALVEELQVTPRRPGSDRWIAVVAEGGLIGGANAEQSQKSVGGNHRDTRL
: . . .
MMAR_1262|M.marinum_M KADGD-DWILNGTKCWITNGGKSSWYTVMAVTDP-----EKGANGISAFM
MUL_2626|M.ulcerans_Agy99 KADGD-DWILNGTKCWITNGGKSSWYTVMAVTDP-----ENGANGISAFV
Mb3302c|M.bovis_AF2122/97 KADGD-HWILNGAKCWITNGGKSTWYTVMAVTDP-----DRGANGISAFM
Rv3274c|M.tuberculosis_H37Rv KADGD-HWILNGAKCWITNGGKSTWYTVMAVTDP-----DRGANGISAFM
MLBr_00737|M.leprae_Br4923 KADGD-DWILNGFKCWITNGGKSTWYTVMAVTDP-----DKGANGISAFI
Mflv_4367|M.gilvum_PYR-GCK KNNGDGTYTIDGQKMWLTNGGSSTLVATLVRTDEGA---DKPHRNLTAFL
MSMEG_4592|M.smegmatis_MC2_155 RNGK--TYCLTGRKVYATGALLGDIIAVQARD---------ESGELVTAL
TH_3393|M.thermoresistible__bu RRGAG-DYLLTGRKFYSTGALFADWIVVRASVPADAADAPTAATPKAVAF
Mvan_3173|M.vanbaalenii_PYR-1 RRDG--HWVLNGTKYYATGTLGATWIAVAARIEG------RENGDTATAF
MAB_1422c|M.abscessus_ATCC_199 LPVGD-AYRLNGEKFYSTGTLFADYLTVTATT---------DRDSVASVI
MAV_3422|M.avium_104 VTTPD-GLRLRGRKFYSTGAQFSDYLRITAQD---------DDGAPTAVV
: * * : *. . . .
MMAR_1262|M.marinum_M VHKDD------EGFVV-GPKERKLGIKGSPTTELYFENCRVPGDRMIGE-
MUL_2626|M.ulcerans_Agy99 VHKDD------EGFVV-GPKERKLGIKGSPTTELYFENCRVPGDRMIGE-
Mb3302c|M.bovis_AF2122/97 VHKDD------EGFTV-GPKERKLGIKGSPTTELYFENCRIPGDRIIGE-
Rv3274c|M.tuberculosis_H37Rv VHKDD------EGFTV-GPKERKLGIKGSPTTELYFENCRIPGDRIIGE-
MLBr_00737|M.leprae_Br4923 VHKDD------EGFSI-GPKEKKLGIKGSPTTELYFDKCRIPGDRIIGE-
Mflv_4367|M.gilvum_PYR-GCK IEKPTGFGEVAPGLTI-PGKLDKLGYKGIDTTELIFDGYRADAGDILGEA
MSMEG_4592|M.smegmatis_MC2_155 VDRYA------HGVTI-VDDWSGFGQRTTASGTAVFDGVEVDETGVLRFG
TH_3393|M.thermoresistible__bu VPRHA------PGLTV-IDDWDGMGQRTTASGSVTLDEVRVPADHVVPFT
Mvan_3173|M.vanbaalenii_PYR-1 VRPDQ------EGVTLDLESWSAFGQRGTASGEVRLNNVVVDDDLLIDEG
MAB_1422c|M.abscessus_ATCC_199 VPGDR------DGVRL-VDDWDGFGQRRTGTGTTIFSQVDVAADEILSET
MAV_3422|M.avium_104 IPVDR------AGVEH-LDDWDGIGQRQTGSGTTVFNDVAVADDEVFPLG
: *. . :* : : :. :.
MMAR_1262|M.marinum_M PGTGFK--TALATLDHTRPTIGAQAVGIAQGALDAAIAYTKDRKQ-----
MUL_2626|M.ulcerans_Agy99 PGTGFK--TALATLDHTRPTIGAQAVGIAQGALDAAIAYTKDRKQ-----
Mb3302c|M.bovis_AF2122/97 PGTGFK--TALATLDHTRPTIGAQAVGIAQGALDAAIAYTKDRKQ-----
Rv3274c|M.tuberculosis_H37Rv PGTGFK--TALATLDHTRPTIGAQAVGIAQGALDAAIAYTKDRKQ-----
MLBr_00737|M.leprae_Br4923 PGTGFK--TALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQ-----
Mflv_4367|M.gilvum_PYR-GCK PGQGFF--QMMDGVEVGRVNVSARACGVGIRAFELAVKYAQQRST-----
MSMEG_4592|M.smegmatis_MC2_155 SDP----HPRYRASAQSQLLHCAIDTGIAQGAFEAAVRLAHQVHG----G
TH_3393|M.thermoresistible__bu PIF----RRPTVYGARAQLWHAALDVGIATAALEEGVRLAARARP----H
Mvan_3173|M.vanbaalenii_PYR-1 PPPDPITADPSVLGAFDQALHAAIDIGIARAALEDGAVFVRTRSRPWKEA
MAB_1422c|M.abscessus_ATCC_199 PYDAAP--VPTTQYASLQLYILAIVAGVLRAVVDDGEALLRSRQR---NF
MAV_3422|M.avium_104 --STIG--VNRARGALVQLYLHAVAAGILRSLTEDAAALVRGRRR---TY
: * *: : .
MMAR_1262|M.marinum_M ---FGKSISDFQAVQFMLADMAMKVESARLMVYSAAARAE----------
MUL_2626|M.ulcerans_Agy99 ---FGKSISDFQAVQFMLADMAMKVESARLMVYSAAARAE----------
Mb3302c|M.bovis_AF2122/97 ---FGESISTFQAVQFMLADMAMKVEAARLMVYSAAARAE----------
Rv3274c|M.tuberculosis_H37Rv ---FGESISTFQAVQFMLADMAMKVEAARLMVYSAAARAE----------
MLBr_00737|M.leprae_Br4923 ---FGESISTFQSIQFMLADMAMKVEAARLIVYAAAARAE----------
Mflv_4367|M.gilvum_PYR-GCK ---FGKPIAEHQAIAFQLAEMATKVEAAHLMMVNAARHKD----------
MSMEG_4592|M.smegmatis_MC2_155 RGSGAVEFTDDVLGVSRLGELWITVEGARAIVTHAAQALDALTDT-----
TH_3393|M.thermoresistible__bu FESGAPVATDDPTLIQSAGEVAVTVRAAQALLGEAARAVDAATAD-----
Mvan_3173|M.vanbaalenii_PYR-1 LDAGIERADQEPHVVRRFGELTARLYALEALLARGTALIDEAYAAP---E
MAB_1422c|M.abscessus_ATCC_199 SHALTERPVDDPLLQRTLGELSATAFAAEATVLAAADAIEAATATLRDGV
MAV_3422|M.avium_104 TFASADTPTADPQLLQIVGEIDAVAYTAHALVRNAAAELAPALQAARDTG
.:: . : .:
MMAR_1262|M.marinum_M ---RGESNLGFISAASKCLASDVAMEVTTDAVQLFGGAGYTVDFPVERMM
MUL_2626|M.ulcerans_Agy99 ---RGESNLGFISAASKCLASDVAMEVTTDAVQLFGGAGYTVDFPVERMM
Mb3302c|M.bovis_AF2122/97 ---RGEPDLGFISAASKCFASDVAMEVTTDAVQLFGGAGYTTDFPVERFM
Rv3274c|M.tuberculosis_H37Rv ---RGEPDLGFISAASKCFASDVAMEVTTDAVQLFGGAGYTTDFPVERFM
MLBr_00737|M.leprae_Br4923 ---RGEPDLGFISAASKCFASDIAMEVTTDAVQLFGGAGYTSDFPVERFM
Mflv_4367|M.gilvum_PYR-GCK ---SGERND-VAAGMAKYFASEVCAEVTQQSFRIHGGYGYSKEYEIERLM
MSMEG_4592|M.smegmatis_MC2_155 DPLDKVLDAFYRVAAAKSISTEAALTVTAALIDIGGASSTRTELRLDRFW
TH_3393|M.thermoresistible__bu LTEDTAAAASIAVATAKVAAERAALRASTALFELGGTRSATVSANLSRFW
Mvan_3173|M.vanbaalenii_PYR-1 VTRDAAAQASLTVAAAKALAQQDAVEIAGAIFELTGTSGTDGAVNLDRHW
MAB_1422c|M.abscessus_ATCC_199 PDAQLAQEAQVAVAKAKVHIDAVALDAATKLLDLGGASAASRTRNLDRHW
MAV_3422|M.avium_104 IDPELEAAASIAAARVKVAIQEPALRAASRVFDAGGASAVQASALLDRHW
. * . : . * . :.*
MMAR_1262|M.marinum_M RDAKITQIYEGTNQIQRVVMSRALLR------------------------
MUL_2626|M.ulcerans_Agy99 RDAKITQIYEGTNQIQRVVMSRALLR------------------------
Mb3302c|M.bovis_AF2122/97 RDAKITQIYEGTNQIQRVVMSRALLR------------------------
Rv3274c|M.tuberculosis_H37Rv RDAKITQIYEGTNQIQRVVMSRALLR------------------------
MLBr_00737|M.leprae_Br4923 RDAKITQIYEGTNQIQRVVMSRALLR------------------------
Mflv_4367|M.gilvum_PYR-GCK RDAPFLLIGEGTSEIQKNIISKRLLADYRV--------------------
MSMEG_4592|M.smegmatis_MC2_155 RDARTHTVHDAVRWKPYSIGRRLLTGDVADAWSIAHPFTPVDDLVHLAST
TH_3393|M.thermoresistible__bu RDARTHTLHDPTRWKLHHIGRYLLSGTRPPRHGQL---------------
Mvan_3173|M.vanbaalenii_PYR-1 RNVRVHSLHDPARWKYVHLGNHTLHDTRPPRLGLIL--------------
MAB_1422c|M.abscessus_ATCC_199 RNIRTISLHNPVHYKARVIGQNLLHGTPLPANAYF---------------
MAV_3422|M.avium_104 RNLRTLFSHNPTVYKARVLGDVVVNGAALPDTSFF---------------
*: : . : :
MMAR_1262|M.marinum_M --
MUL_2626|M.ulcerans_Agy99 --
Mb3302c|M.bovis_AF2122/97 --
Rv3274c|M.tuberculosis_H37Rv --
MLBr_00737|M.leprae_Br4923 --
Mflv_4367|M.gilvum_PYR-GCK --
MSMEG_4592|M.smegmatis_MC2_155 RA
TH_3393|M.thermoresistible__bu --
Mvan_3173|M.vanbaalenii_PYR-1 --
MAB_1422c|M.abscessus_ATCC_199 --
MAV_3422|M.avium_104 --