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VSEYSLTMSTSGRDRLLSAALKLFAAKGYAATSVADIQRCSGLAPGSGALYKHFGSKHELLEAAVEHRID SIVAAREQYDAGEPGGVEQAVRTAGHLIWTNLKQSEDLLKVMLREPGALGDLDEKTWQIITDNAYQRFAD ELAASNRSGRTRIPDPEAAASVAIASLSYAATLQALTGRSPGNIDDSRYFEAWVNQTVSMLSQYTNPAPS RKP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0150 | - | - | 100% (214) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1444 | - | 7e-14 | 53.23% (62) | TetR family transcriptional regulator |
| M. marinum M | MMAR_5046 | - | 2e-07 | 35.80% (81) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0310 | - | 4e-10 | 45.45% (77) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4599 | - | 9e-08 | 42.62% (61) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0302 | - | 4e-10 | 45.45% (77) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3313c | - | 2e-15 | 32.82% (131) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0146 | - | 3e-96 | 85.92% (206) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0532 | - | 3e-84 | 77.44% (195) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2855 | - | 2e-08 | 30.43% (161) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4947 | - | 1e-114 | 99.03% (206) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5283 | - | 4e-08 | 37.66% (77) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0150|M.marinum_M ----------------------------MVSEYSLTMSTSGRDRLLSAAL
MUL_4947|M.ulcerans_Agy99 ------------------------------------MSTSGRDRLLSAAL
MAV_0146|M.avium_104 ------------------------------------MLSSGRDRLLSAAL
MSMEG_0532|M.smegmatis_MC2_155 -------------------------------------MSAARDRLMAAAL
Mb0310|M.bovis_AF2122/97 --------------------------MGVPAKKKQQQGERSRESILDATE
Rv0302|M.tuberculosis_H37Rv --------------------------MGVPAKKKQQQGERSRESILDATE
MAB_3313c|M.abscessus_ATCC_199 -----------------------------------MGEISTKERLVTEAM
Mflv_4599|M.gilvum_PYR-GCK -------------------------MNKVVVAGRTRVGGERRERILASAT
TH_2855|M.thermoresistible__bu LSQSPDNATSSSRAGSGAGSGAGSGAEPIGRDTPRRRPRIRPEEIVSAAA
Mvan_5283|M.vanbaalenii_PYR-1 -----------------------------MSSGQAPQANTRRDELLQLAA
: :: :
MMAR_0150|M.marinum_M KLFAAKGYAATSVADIQRCSGLAPGSGALYKHFGSKHELLEAAVEHRIDS
MUL_4947|M.ulcerans_Agy99 KLFAVKGYAATSVADIQRCSGLAPGSGALYKHFGSKHELLEAAVEHRIDS
MAV_0146|M.avium_104 RLFAAKGYAATSVADIQRESGLAPGSGALYKHFGSKRELLEAAVAHRIES
MSMEG_0532|M.smegmatis_MC2_155 KLFAAKGYAATSVAEIQQQAGLAPGSGALYKHFGSKRELLEAAITHRIDN
Mb0310|M.bovis_AF2122/97 RLMATKGYAATSISDIRDACGLAPSS--IYWHFGSKEGVLAAMMERGAQR
Rv0302|M.tuberculosis_H37Rv RLMATKGYAATSISDIRDACGLAPSS--IYWHFGSKEGVLAAMMERGAQR
MAB_3313c|M.abscessus_ATCC_199 RLFGEQGYKATSVAQIEKAAGLTPGSGGLYHHFKSKEALLEAGIDRQLDR
Mflv_4599|M.gilvum_PYR-GCK ELIAERGYHAVSMADIGVASGVVGPA--IYRHFNSKSDLLAALFERVVDK
TH_2855|M.thermoresistible__bu EFFAREGYANVGMRDVAEAVGIRGAS--LYHHFGSKEEILYAICLTVTKE
Mvan_5283|M.vanbaalenii_PYR-1 TMFAERGLRATTVRDIADSAGILSGS--LYHHFSSKEEMVDEVLRGFLDW
::. .* . : :: *: : :* ** ** :: .
MMAR_0150|M.marinum_M IVAAREQYDAGE-PGGVEQAVRTAGHLIWTNLKQSEDL-LKVMLREPGAL
MUL_4947|M.ulcerans_Agy99 IVAAREQYDAGE-PGGVEQAVRTAGHLIWTNLKQSEDL-LKVMLREPGAL
MAV_0146|M.avium_104 IVTAREQYDAGQ-PGSVEQAVRTAGQLIWNNLKQSEDL-LKVMLREPDEL
MSMEG_0532|M.smegmatis_MC2_155 IVAAREQYDAEK-PRTVEDAVRSAGQLIWTNLTQSEEL-LRVMLREPDEL
Mb0310|M.bovis_AF2122/97 FFAAIPTWDEAH-GPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQ
Rv0302|M.tuberculosis_H37Rv FFAAIPTWDEAH-GPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQ
MAB_3313c|M.abscessus_ATCC_199 RRAMRDIRALFGGLGDLRNELTMMGRYVLAVLDEESQL-LQIASSVPSGR
Mflv_4599|M.gilvum_PYR-GCK LLKRATAIVEQS-RDEAEALTLLVSDQVALVMDQRELA--MVYYREVHNL
TH_2855|M.thermoresistible__bu PNELNLPLLDAAGTPAERLSALIRAHLEHLIRRRVEHL---VALHDINSL
Mvan_5283|M.vanbaalenii_PYR-1 LFDRYQQIVATEPNPLERLKGLFMASFEAIETRHAEVV---IYQDEAKRL
. . .
MMAR_0150|M.marinum_M GDLDEKTWQIITDNAYQRFADELAASNRSGRTRIPDPEAAASV-AIASLS
MUL_4947|M.ulcerans_Agy99 GDLDEKTWQIITDNAYQRFADELAASNRSGRTRIPDPEAAASV-AIASLS
MAV_0146|M.avium_104 GDLDEKTWQVITDNAYQRFADELAASNRAGRTSIPDPEAAAAV-AIGSLS
MSMEG_0532|M.smegmatis_MC2_155 GDLDEKTWQVITDNAYQRFADELAASNRAGRTEIPDPEATAAV-AIASLS
Mb0310|M.bovis_AF2122/97 DPVVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAEL-TAFAVA
Rv0302|M.tuberculosis_H37Rv DPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAEL-TAFAVA
MAB_3313c|M.abscessus_ATCC_199 PARLDHAYAALFDGLYGELSDWVQG--WAPDISKQDAESIGVL-GVNALL
Mflv_4599|M.gilvum_PYR-GCK SDQHQSRLRRKQRLYLEEWVHLVGELRPAVDEIELRAMVHGAIGAIQSIL
TH_2855|M.thermoresistible__bu TPEHRAIIDDLRRYYQRRVRDVIVAGVRSGEFDVPDPKLAALL--ILDAL
Mvan_5283|M.vanbaalenii_PYR-1 SAQGRFAYVEERNKEQRKMWVDVLTQGIDEGYFRPDVDVDLVYRFIRDTT
. :
MMAR_0150|M.marinum_M YAATLQALTGRSPGNIDDSRYFEAWVNQTVSMLSQYTN-PAPSRKP----
MUL_4947|M.ulcerans_Agy99 YALTLQALTGRSPGNIDDSRYFEAWVNQTVSMLSQYTN-PAPSRKPQADN
MAV_0146|M.avium_104 YAATLQALTGRLPGNTDEDRYFEAWVNQTVSVLAQYTNRRKPLNDNDNDS
MSMEG_0532|M.smegmatis_MC2_155 YVATLHALNGRTPGNVDHDRFFEAWVAQTVAAIEQHRTDNQTDNR-----
Mb0310|M.bovis_AF2122/97 LSDGVYFAGHLEPDTTDVERMYRRLRQALEALIPVLLEET----------
Rv0302|M.tuberculosis_H37Rv LSDGVYFAGHLEPDTTDVERMYRRLRQALEALIPVLLEET----------
MAB_3313c|M.abscessus_ATCC_199 GKRATSAVFRGAARDIADEDYVVEWTALLAMRIESLR-------------
Mflv_4599|M.gilvum_PYR-GCK HYRGTGLAPEQTSALLVAMGHAVLGVPASSHQVRGVNTEPSCPRPGTPQH
TH_2855|M.thermoresistible__bu NGVSGWFHPDRGHSLPDVIAAYTEMIVERVLRARIS--------------
Mvan_5283|M.vanbaalenii_PYR-1 WVSVRWYQPGGPLTAQQVGRQYLSIVLGGITAEPTSKESTNG--------
MMAR_0150|M.marinum_M ----
MUL_4947|M.ulcerans_Agy99 KFQE
MAV_0146|M.avium_104 GAQT
MSMEG_0532|M.smegmatis_MC2_155 ----
Mb0310|M.bovis_AF2122/97 ----
Rv0302|M.tuberculosis_H37Rv ----
MAB_3313c|M.abscessus_ATCC_199 ----
Mflv_4599|M.gilvum_PYR-GCK ----
TH_2855|M.thermoresistible__bu ----
Mvan_5283|M.vanbaalenii_PYR-1 ----