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SSSPSALSRVERKKREMRQEILDSAFACFAEQGYHATGVADIAGRIGIGHGTFYRYFKSKRDIIEHVIDD VTGQIFEAIGAENAAGLADDIEQYRQQSVRIGAALAHLFRENPHLPLLLLEAGSVDSELRERVFGMLSTS DHLTEAYLRHGVEKGYLRADLDTEYTARAVTGMILANGLHASRGGEVQDTERFSAAVIALMYGGIGP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1525c | - | - | 100% (208) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1379c | - | 1e-41 | 40.89% (203) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4946 | - | 4e-28 | 36.93% (176) | putative transcriptional regulator, TetR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3587c | - | 2e-09 | 25.00% (200) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1483 | - | 1e-10 | 25.25% (202) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3557c | - | 2e-09 | 25.00% (200) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 8e-06 | 35.48% (62) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_5046 | - | 3e-09 | 25.12% (203) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0603 | - | 5e-10 | 26.94% (193) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1565 | - | 3e-10 | 28.40% (169) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2600 | - | 7e-10 | 24.35% (193) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_0905 | - | 4e-08 | 31.11% (90) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1893 | - | 6e-09 | 24.14% (203) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3587c|M.bovis_AF2122/97 ------------MDRVAG-----------------QVNSRRGELLELAAA
Rv3557c|M.tuberculosis_H37Rv ------------MDRVAG-----------------QVNSRRGELLELAAA
MMAR_5046|M.marinum_M ------------MERMTG-----------------QANSRRGELLGLAAV
MAV_0603|M.avium_104 ---------------MTG-----------------PANSRRDELLELAAA
Mflv_1483|M.gilvum_PYR-GCK ---------------MDR-----------------ALPSRRDELLQLAAT
MAB_1525c|M.abscessus_ATCC_199 -----MSSSPSALSRVER-----------------KKREMRQEILDSAFA
MSMEG_1565|M.smegmatis_MC2_155 -MRQTRAARSGPGRPAGT-----------------DSVDTRQRVIDAACR
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
TH_2600|M.thermoresistible__bu -MSKPRVRNRYSSGPTRG-------------------EQRRERLLQALED
Mvan_1893|M.vanbaalenii_PYR-1 -----MPPGPAESLSAKG-------------------RQTRDAIEQAARK
MUL_0905|M.ulcerans_Agy99 --MTTGSAIRSRKTPTGR-------------------EEVAAAVLEAAAD
. :
Mb3587c|M.bovis_AF2122/97 MFAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLFA
Rv3557c|M.tuberculosis_H37Rv MFAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLFA
MMAR_5046|M.marinum_M MFAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLREFLDWLFA
MAV_0603|M.avium_104 MFAERGLRATTVRDIADSAGILSGSLYHHFSSKEEMVDEVLRSFLDWLFA
Mflv_1483|M.gilvum_PYR-GCK MFADRGLRATTVRDIADSAGILSGSLYHHFKSKEQMVEEVLKDFLDWLFT
MAB_1525c|M.abscessus_ATCC_199 CFAEQGYHATGVADIAGRIGIGHGTFYRYFKSKRDIIEHVIDDVTGQIFE
MSMEG_1565|M.smegmatis_MC2_155 CFAQFGYGPATNNQIAEMAGVTAGSVYYHFGTKNKLFEAVCDDVYGKILT
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
TH_2600|M.thermoresistible__bu LLASRPFAAIEVGDIARAAGLSRSAFYFYFPSKAAAVGAMLGDVFGEISD
Mvan_1893|M.vanbaalenii_PYR-1 LFAERGFHGTTLGDITSAAGKSPAVFYRYFADKEDLLAALAESFLHDVVA
MUL_0905|M.ulcerans_Agy99 LFAERGPAATSIRDIAARSKVNHGLVFRHFGAKEQLVGAVLDYLGTHLTE
:.. :*: .: :* * : :
Mb3587c|M.bovis_AF2122/97 RY-RDIVDSTANPLERLQG---LFMASFEAIEHHHAQVVIYQDEAQRLAS
Rv3557c|M.tuberculosis_H37Rv RY-RDIVDSTANPLERLQG---LFMASFEAIEHHHAQVVIYQDEAQRLAS
MMAR_5046|M.marinum_M RY-LEIVDGEPNPLERLKG---LFLASFEAIEHRHAQVVIYQDEAQRLSS
MAV_0603|M.avium_104 RY-REIIDSESNPLERLKG---LFMASFEAIEHRHAQVVIYQDEAKRLLS
Mflv_1483|M.gilvum_PYR-GCK RY-DEIVAATTDPLERVSG---LFMVSFEAIEHRHAQVVIYQDEAKRLNS
MAB_1525c|M.abscessus_ATCC_199 AIGAENAAGLADDIEQYRQQSVRIGAALAHLFRENPHLPLLLLEAGSVDS
MSMEG_1565|M.smegmatis_MC2_155 RV-MLAVSGSHSVVGLLRA----VLTESMRINHESPELAGFVATAPIDAR
MLBr_00815|M.leprae_Br4923 SV-QQALRTTTNNRQRLHA---AVQAFFDFIEHDGQGYRLIFENDNITEP
TH_2600|M.thermoresistible__bu VLDKWTELGDSVAARRREVY--DSFERVVAIWRQHAPLMAAMFDAASTDA
Mvan_1893|M.vanbaalenii_PYR-1 PSGLSVPLPESPDDDAFFT---MVVTGYWTMFKQNIGIMIAVAQLAATQS
MUL_0905|M.ulcerans_Agy99 LLRAGTPADDLERALDRQMR---VWARTLLDGYPAEQLQTRFPNVAELLG
Mb3587c|M.bovis_AF2122/97 QPR--FSYIEDRNKQQRKMWVDVLNQGIEEGYFRPDLDVDLVYRFIRDTT
Rv3557c|M.tuberculosis_H37Rv QPR--FSYIEDRNKQQRKMWVDVLNQGIEEGYFRPDLDVDLVYRFIRDTT
MMAR_5046|M.marinum_M QPR--FSYLEDRNKEQRKMWVDVLNQGIEEGYFRPDLDVDLVYRFIRDTT
MAV_0603|M.avium_104 QPR--FSYIEDMNRQQRKMWLEVLNQGVDEGYFRPDLDVDLVYRFIRDTT
Mflv_1483|M.gilvum_PYR-GCK LPQ--FGFLDDRNRQQRRMWVEVLKQGIAEGSFRPDIDVDLVYRFIRDTT
MAB_1525c|M.abscessus_ATCC_199 ELR--ERVFG-MLSTSDHLTEAYLRHGVEKGYLRADLDTEYTARAVTGMI
MSMEG_1565|M.smegmatis_MC2_155 RHRELAESFATQGARMADALTDAVRSGQDAGDIAADLDPVRVARLIS-AV
MLBr_00815|M.leprae_Br4923 R-------VAAQVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGIS
TH_2600|M.thermoresistible__bu EVR---AMFEGHIDSFVDGSAARIRHERAVGEAPDGPDPEALARVLVGMN
Mvan_1893|M.vanbaalenii_PYR-1 RFA---LVQNEFRRFGMDIVAASVRRAQEQGYGRELNAEHTAAAIALLFE
MUL_0905|M.ulcerans_Agy99 QVR--------------------VHHGDDTTARLAVANAIALCLGWRLFE
:
Mb3587c|M.bovis_AF2122/97 WVS-VRWYRPGGP-LTAQQVGQQYLAIVLGGITKEGV---
Rv3557c|M.tuberculosis_H37Rv WVS-VRWYRPGGP-LTAQQVGQQYLAIVLGGITKEGV---
MMAR_5046|M.marinum_M WVS-VRWYKPGGA-LTAQQVGQKYLAIVLGGIQKEGV---
MAV_0603|M.avium_104 WVS-VRWYQPGGP-LTAEQVGQQYLAIVLGGITVDAKKD-
Mflv_1483|M.gilvum_PYR-GCK WVS-VRWYQPGGP-LTAEQVGRQYLAIVLGGITEGSK---
MAB_1525c|M.abscessus_ATCC_199 LANGLHASRGGEV-QDTERFSAAVIALMYGGIGP------
MSMEG_1565|M.smegmatis_MC2_155 VDGFAHAAVSADP-DEMDNMNELFQSLLLDTT--------
MLBr_00815|M.leprae_Br4923 VDCARYWLDTNRP-ISKSDAVEGTVQFAWGGLSHVPLTRL
TH_2600|M.thermoresistible__bu VKALERDMRAITSGAPADADLPRVLAFVWGRVLYDA----
Mvan_1893|M.vanbaalenii_PYR-1 NFTTVFVGASGLDVDIDDEAAIATLSRIWKKTLYGY----
MUL_0905|M.ulcerans_Agy99 PMLRSATGLDELADADLRQAVTDEVARIIEPSGRG-----