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LSSGRDRLLSAALRLFAAKGYAATSVADIQRESGLAPGSGALYKHFGSKRELLEAAVAHRIESIVTAREQ YDAGQPGSVEQAVRTAGQLIWNNLKQSEDLLKVMLREPDELGDLDEKTWQVITDNAYQRFADELAASNRA GRTSIPDPEAAAAVAIGSLSYAATLQALTGRLPGNTDEDRYFEAWVNQTVSVLAQYTNRRKPLNDNDNDS GAQT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0146 | - | - | 100% (215) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_0586 | - | 2e-08 | 28.12% (160) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_0603 | - | 2e-06 | 45.28% (53) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1561 | - | 3e-11 | 31.89% (185) | transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2198 | - | 3e-07 | 27.15% (151) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1534 | - | 3e-11 | 31.89% (185) | transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3313c | - | 7e-15 | 29.73% (185) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0150 | - | 3e-96 | 85.92% (206) | TetR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0532 | - | 2e-87 | 75.24% (210) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3524 | - | 5e-08 | 26.62% (154) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4947 | - | 3e-96 | 84.29% (210) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0170 | - | 1e-07 | 41.56% (77) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0150|M.marinum_M -------MVSEYSLTMSTSGRDRLLSAALKLFAAKGYAATSVADIQRCSG
MUL_4947|M.ulcerans_Agy99 ---------------MSTSGRDRLLSAALKLFAVKGYAATSVADIQRCSG
MAV_0146|M.avium_104 ---------------MLSSGRDRLLSAALRLFAAKGYAATSVADIQRESG
MSMEG_0532|M.smegmatis_MC2_155 ----------------MSAARDRLMAAALKLFAAKGYAATSVAEIQQQAG
Mb1561|M.bovis_AF2122/97 MSRASARRRRAVSDEDKSQRRDEILAAAKIVFAHKGFHATTVADIAKQAG
Rv1534|M.tuberculosis_H37Rv MSRASARRRRAVSDEDKSQRRDEILAAAKIVFAHKGFHATTVADIAKQAG
MAB_3313c|M.abscessus_ATCC_199 --------------MGEISTKERLVTEAMRLFGEQGYKATSVAQIEKAAG
Mvan_0170|M.vanbaalenii_PYR-1 ------MTTASSAQMPPQSARQRVLDVALALFTRHGYAGTSLQMIADEMG
Mflv_2198|M.gilvum_PYR-GCK -----------MRSVDDLTAAARIRDAAVELFGAEGFAVS-VRTIAAAAG
TH_3524|M.thermoresistible__bu --------------VRGHRNREALIAAAIDLFTVNGYEQTTVEQIAEAAG
: * :* .*: : : * *
MMAR_0150|M.marinum_M LAPGSGALYKHFGSKHELLEAAVEHRIDSIVAAREQYDAGE-PGGVEQAV
MUL_4947|M.ulcerans_Agy99 LAPGSGALYKHFGSKHELLEAAVEHRIDSIVAAREQYDAGE-PGGVEQAV
MAV_0146|M.avium_104 LAPGSGALYKHFGSKRELLEAAVAHRIESIVTAREQYDAGQ-PGSVEQAV
MSMEG_0532|M.smegmatis_MC2_155 LAPGSGALYKHFGSKRELLEAAITHRIDNIVAAREQYDAEK-PRTVEDAV
Mb1561|M.bovis_AF2122/97 LAYG--LIYWYFDSKDDLFHALMAGEEEALRAHVAAELARV-GGSTEAPL
Rv1534|M.tuberculosis_H37Rv LAYG--LIYWYFDSKDDLFHALMAGEEEALRAHVAAELARV-GGSTEAPL
MAB_3313c|M.abscessus_ATCC_199 LTPGSGGLYHHFKSKEALLEAGIDRQLDRRRAMRDIRALFGGLGDLRNEL
Mvan_0170|M.vanbaalenii_PYR-1 VTKG--SLYYHFRAREDLLRALVGPLIEQLRAIVEHAEAQR-----SPSV
Mflv_2198|M.gilvum_PYR-GCK VSPG--LVIHHFGSKDQLHKACDAYVAETVRAAKSESIQTSDPATWLAQM
TH_3524|M.thermoresistible__bu VAPR--TFFRHFAAKEDILFHGYADRLAEATRRFRAARSGS----LWKAL
:: . :* :: : :
MMAR_0150|M.marinum_M R------TAGHLIWTNLKQSEDLLKVMLR------EPGALGDLDEKTWQI
MUL_4947|M.ulcerans_Agy99 R------TAGHLIWTNLKQSEDLLKVMLR------EPGALGDLDEKTWQI
MAV_0146|M.avium_104 R------TAGQLIWNNLKQSEDLLKVMLR------EPDELGDLDEKTWQV
MSMEG_0532|M.smegmatis_MC2_155 R------SAGQLIWTNLTQSEELLRVMLR------EPDELGDLDEKTWQV
Mb1561|M.bovis_AF2122/97 RALLQ--AAVQATFEFFETDKATVKLLFR------DAYALGGRFEEHLGG
Rv1534|M.tuberculosis_H37Rv RALLQ--AAVQATFEFFETDKATVKLLFR------DAYALGGRFEEHLGG
MAB_3313c|M.abscessus_ATCC_199 T------MMGRYVLAVLDEESQLLQIASS------VPSGRPARLDHAYAA
Mvan_0170|M.vanbaalenii_PYR-1 R--------AEHVLTGYARLAAANRALVA------VTSGD--------PS
Mflv_2198|M.gilvum_PYR-GCK AEIEEYAPLMAYLVRSLQAGGELGKMLWRTMTNDVEQYLEDGVRAGTVKP
TH_3524|M.thermoresistible__bu A------EASEAVATAIAENPGIFLVRAR-------MYGELPALRATMLR
MMAR_0150|M.marinum_M ITDNAYQRFADELAASNRSGRTRIPDPEAAASVAIASLSYAATLQALTGR
MUL_4947|M.ulcerans_Agy99 ITDNAYQRFADELAASNRSGRTRIPDPEAAASVAIASLSYALTLQALTGR
MAV_0146|M.avium_104 ITDNAYQRFADELAASNRAGRTSIPDPEAAAAVAIGSLSYAATLQALTGR
MSMEG_0532|M.smegmatis_MC2_155 ITDNAYQRFADELAASNRAGRTEIPDPEATAAVAIASLSYVATLHALNGR
Mb1561|M.bovis_AF2122/97 IYERFIDDIEAVVVAAQRRG-EVVEAPSRMAAYTLAALVGQLAHRRLN--
Rv1534|M.tuberculosis_H37Rv IYERFIDDIEAVVVAAQRRG-EVVEAPSRMAAYTLAALVGQLAHRRLN--
MAB_3313c|M.abscessus_ATCC_199 LFDGLYGELSDWVQG--WAPDISKQDAESIGVLGVNALLGKRATSAVFRG
Mvan_0170|M.vanbaalenii_PYR-1 VVEVIHADPDWADLIDRQIGLLAAVQPGLAGRVRATIVMAGIAATAAPGV
Mflv_2198|M.gilvum_PYR-GCK SADPRARAFFLSMASGGGFLLYLQLHESTDIRVVLRDYSEAMVLPALELY
TH_3524|M.thermoresistible__bu INDDWIDQMTTEVARWLGSDAAVDVRPRLAATVINGANRTAIDLWVSADG
:
MMAR_0150|M.marinum_M SPGNIDDSRYFEAWVNQTVSMLSQYTN-PAPSRKP--------
MUL_4947|M.ulcerans_Agy99 SPGNIDDSRYFEAWVNQTVSMLSQYTN-PAPSRKPQADNKFQE
MAV_0146|M.avium_104 LPGNTDEDRYFEAWVNQTVSVLAQYTNRRKPLNDNDNDSGAQT
MSMEG_0532|M.smegmatis_MC2_155 TPGNVDHDRFFEAWVAQTVAAIEQHRT------DNQTDNR---
Mb1561|M.bovis_AF2122/97 TDDNVTAAQVADFVVSLVLDGLRPRALAVGARGGRAART----
Rv1534|M.tuberculosis_H37Rv TDDNVTAAQVADFVVSLVLDGLRPRALAVGARGGRAART----
MAB_3313c|M.abscessus_ATCC_199 AARDIADEDYVVEWTALLAMRIESLR-----------------
Mvan_0170|M.vanbaalenii_PYR-1 VEADEAELCRQLIDAGRRTLGLRAPRA----------------
Mflv_2198|M.gilvum_PYR-GCK THGLLTDSTMYDAFVAERAHDHSSPSTGARDA-----------
TH_3524|M.thermoresistible__bu KGDLVELMADAVRLVRPTLDRIERESRTVANPVRRRDVV----
.