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MSTSGRDRLLSAALKLFAVKGYAATSVADIQRCSGLAPGSGALYKHFGSKHELLEAAVEHRIDSIVAARE QYDAGEPGGVEQAVRTAGHLIWTNLKQSEDLLKVMLREPGALGDLDEKTWQIITDNAYQRFADELAASNR SGRTRIPDPEAAASVAIASLSYALTLQALTGRSPGNIDDSRYFEAWVNQTVSMLSQYTNPAPSRKPQADN KFQE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4947 | - | - | 100% (214) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_0145 | - | 2e-06 | 34.57% (81) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_4120 | - | 4e-06 | 35.62% (73) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0310 | - | 4e-10 | 45.45% (77) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4599 | - | 1e-07 | 42.62% (61) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0302 | - | 4e-10 | 45.45% (77) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3313c | - | 3e-15 | 32.82% (131) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0150 | - | 1e-114 | 99.03% (206) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0146 | - | 3e-96 | 84.29% (210) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0532 | - | 3e-83 | 76.41% (195) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3524 | - | 3e-08 | 27.33% (150) | PUTATIVE - |
| M. vanbaalenii PYR-1 | Mvan_5283 | - | 6e-08 | 37.66% (77) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4947|M.ulcerans_Agy99 -----------MSTSGRDRLLSAALKLFAVKGYAATSVADIQRCSGLAPG
MMAR_0150|M.marinum_M ---MVSEYSLTMSTSGRDRLLSAALKLFAAKGYAATSVADIQRCSGLAPG
MAV_0146|M.avium_104 -----------MLSSGRDRLLSAALRLFAAKGYAATSVADIQRESGLAPG
MSMEG_0532|M.smegmatis_MC2_155 ------------MSAARDRLMAAALKLFAAKGYAATSVAEIQQQAGLAPG
Mb0310|M.bovis_AF2122/97 -MGVPAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPS
Rv0302|M.tuberculosis_H37Rv -MGVPAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPS
MAB_3313c|M.abscessus_ATCC_199 ----------MGEISTKERLVTEAMRLFGEQGYKATSVAQIEKAAGLTPG
TH_3524|M.thermoresistible__bu ----------VRGHRNREALIAAAIDLFTVNGYEQTTVEQIAEAAGVAPR
Mflv_4599|M.gilvum_PYR-GCK MNKVVVAGRTRVGGERRERILASATELIAERGYHAVSMADIGVASGVVGP
Mvan_5283|M.vanbaalenii_PYR-1 ----MSSGQAPQANTRRDELLQLAATMFAERGLRATTVRDIADSAGILSG
:: :: : :: .* .:: :* .*:
MUL_4947|M.ulcerans_Agy99 SGALYKHFGSKHELLEAAVEHRIDSIVAAREQYDAGE-PGGVEQAVRTAG
MMAR_0150|M.marinum_M SGALYKHFGSKHELLEAAVEHRIDSIVAAREQYDAGE-PGGVEQAVRTAG
MAV_0146|M.avium_104 SGALYKHFGSKRELLEAAVAHRIESIVTAREQYDAGQ-PGSVEQAVRTAG
MSMEG_0532|M.smegmatis_MC2_155 SGALYKHFGSKRELLEAAITHRIDNIVAAREQYDAEK-PRTVEDAVRSAG
Mb0310|M.bovis_AF2122/97 S--IYWHFGSKEGVLAAMMERGAQRFFAAIPTWDEAH-GPVEQRSERQLT
Rv0302|M.tuberculosis_H37Rv S--IYWHFGSKEGVLAAMMERGAQRFFAAIPTWDEAH-GPVEQRSERQLT
MAB_3313c|M.abscessus_ATCC_199 SGGLYHHFKSKEALLEAGIDRQLDRRRAMRDIRALFGGLGDLRNELTMMG
TH_3524|M.thermoresistible__bu T--FFRHFAAKEDILFHGYA---DRLAEATRRFRAAR-SGSLWKALAEAS
Mflv_4599|M.gilvum_PYR-GCK A--IYRHFNSKSDLLAALFERVVDKLLKRATAIVEQS-RDEAEALTLLVS
Mvan_5283|M.vanbaalenii_PYR-1 S--LYHHFSSKEEMVDEVLRGFLDWLFDRYQQIVATE-----PNPLERLK
: :: ** :* :: :
MUL_4947|M.ulcerans_Agy99 HLIWTNLKQSEDL-LKVMLREPGALGDLDEKTWQIITDNAYQRFADELAA
MMAR_0150|M.marinum_M HLIWTNLKQSEDL-LKVMLREPGALGDLDEKTWQIITDNAYQRFADELAA
MAV_0146|M.avium_104 QLIWNNLKQSEDL-LKVMLREPDELGDLDEKTWQVITDNAYQRFADELAA
MSMEG_0532|M.smegmatis_MC2_155 QLIWTNLTQSEEL-LRVMLREPDELGDLDEKTWQVITDNAYQRFADELAA
Mb0310|M.bovis_AF2122/97 ELVSLQSQHPDFLRLFYLLSMERSQDPVVAAVVRRVRNTAIARFRDSITH
Rv0302|M.tuberculosis_H37Rv ELVSLQSQHPDFLRLFYLLSMERSQDPAVAAVVRRVRNTAIARFRDSITH
MAB_3313c|M.abscessus_ATCC_199 RYVLAVLDEESQL-LQIASSVPSGRPARLDHAYAALFDGLYGELSDWVQG
TH_3524|M.thermoresistible__bu EAVATAIAENPGI--FLVRARMYGELPALRATMLRINDDWIDQMTTEVAR
Mflv_4599|M.gilvum_PYR-GCK DQVALVMDQRELA--MVYYREVHNLSDQHQSRLRRKQRLYLEEWVHLVGE
Mvan_5283|M.vanbaalenii_PYR-1 GLFMASFEAIETRHAEVVIYQDEAKRLSAQGRFAYVEERNKEQRKMWVDV
. . :
MUL_4947|M.ulcerans_Agy99 SNRSGRTRIPDPEAAASV-AIASLSYALTLQALTGRSPGNIDDSRYFEAW
MMAR_0150|M.marinum_M SNRSGRTRIPDPEAAASV-AIASLSYAATLQALTGRSPGNIDDSRYFEAW
MAV_0146|M.avium_104 SNRAGRTSIPDPEAAAAV-AIGSLSYAATLQALTGRLPGNTDEDRYFEAW
MSMEG_0532|M.smegmatis_MC2_155 SNRAGRTEIPDPEATAAV-AIASLSYVATLHALNGRTPGNVDHDRFFEAW
Mb0310|M.bovis_AF2122/97 LLPSDIPPGKADLVVAEL-TAFAVALSDGVYFAGHLEPDTTDVERMYRRL
Rv0302|M.tuberculosis_H37Rv LLPSDIPPGKADLVVAEL-TAFAVALSDGVYFAGHLEPDTTDVERMYRRL
MAB_3313c|M.abscessus_ATCC_199 --WAPDISKQDAESIGVL-GVNALLGKRATSAVFRGAARDIADEDYVVEW
TH_3524|M.thermoresistible__bu WLGSDAAVDVRPRLAATV-INGANRTAIDLWVSADGKGDLVELMADAVRL
Mflv_4599|M.gilvum_PYR-GCK LRPAVDEIELRAMVHGAIGAIQSILHYRGTGLAPEQTSALLVAMGHAVLG
Mvan_5283|M.vanbaalenii_PYR-1 LTQGIDEGYFRPDVDVDL-VYRFIRDTTWVSVRWYQPGGPLTAQQVGRQY
. :
MUL_4947|M.ulcerans_Agy99 VNQTVSMLSQYTN-PAPSRKPQADNKFQE
MMAR_0150|M.marinum_M VNQTVSMLSQYTN-PAPSRKP--------
MAV_0146|M.avium_104 VNQTVSVLAQYTNRRKPLNDNDNDSGAQT
MSMEG_0532|M.smegmatis_MC2_155 VAQTVAAIEQHRTDNQTDNR---------
Mb0310|M.bovis_AF2122/97 RQALEALIPVLLEET--------------
Rv0302|M.tuberculosis_H37Rv RQALEALIPVLLEET--------------
MAB_3313c|M.abscessus_ATCC_199 TALLAMRIESLR-----------------
TH_3524|M.thermoresistible__bu VRPTLDRIERESRTVANPVRRRDVV----
Mflv_4599|M.gilvum_PYR-GCK VPASSHQVRGVNTEPSCPRPGTPQH----
Mvan_5283|M.vanbaalenii_PYR-1 LSIVLGGITAEPTSKESTNG---------
: